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Inositol 1,4,5-trisphosphate Receptor Mutations associated with Human Disease. 与人类疾病相关的肌醇1,4,5-三磷酸受体突变。
Messenger (Los Angeles, Calif. : Print) Pub Date : 2018-06-01 DOI: 10.1166/MSR.2018.1075
L. Terry, K. Alzayady, Esraa Furati, D. Yule
{"title":"Inositol 1,4,5-trisphosphate Receptor Mutations associated with Human Disease.","authors":"L. Terry, K. Alzayady, Esraa Furati, D. Yule","doi":"10.1166/MSR.2018.1075","DOIUrl":"https://doi.org/10.1166/MSR.2018.1075","url":null,"abstract":"Calcium release into the cytosol via the inositol 1,4,5-trisphosphate receptor (IP3R) calcium channel is important for a variety of cellular processes. As a result, impairment or inhibition of this release can result in disease. Recently, mutations in all four domains of the IP3R have been suggested to cause diseases such as ataxia, cancer, and anhidrosis; however, most of these mutations have not been functionally characterized. In this review we summarize the reported mutations, as well as the associated symptoms. Additionally, we use clues from transgenic animals, receptor stoichiometry, and domain location of mutations to speculate on the effects of individual mutations on receptor structure and function and the overall mechanism of disease.","PeriodicalId":74176,"journal":{"name":"Messenger (Los Angeles, Calif. : Print)","volume":"6 1-2 1","pages":"29-44"},"PeriodicalIF":0.0,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1166/MSR.2018.1075","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48671333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 30
Seminal CD38: Ever-Expanding Breadth of Its Function in Reproductive Biology 精子CD38:在生殖生物学中不断扩展的功能广度
Messenger (Los Angeles, Calif. : Print) Pub Date : 2018-06-01 DOI: 10.1166/msr.2018.1065
U. Kim
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引用次数: 0
CD38 in the Nucleus Accumbens is Critical in Paternal Behavior in Mice 伏隔核CD38在小鼠父系行为中起关键作用
Messenger (Los Angeles, Calif. : Print) Pub Date : 2018-06-01 DOI: 10.1166/MSR.2018.1063
Shirin Akther, Jing Zhong, Mingkun Liang, Stanislav M. Cherepanov, O. Lopatina, A. Salmina, C. Tsuji, T. Tsuji, Yasuhiko Yamamoto, S. Yokoyama, H. Higashida
{"title":"CD38 in the Nucleus Accumbens is Critical in Paternal Behavior in Mice","authors":"Shirin Akther, Jing Zhong, Mingkun Liang, Stanislav M. Cherepanov, O. Lopatina, A. Salmina, C. Tsuji, T. Tsuji, Yasuhiko Yamamoto, S. Yokoyama, H. Higashida","doi":"10.1166/MSR.2018.1063","DOIUrl":"https://doi.org/10.1166/MSR.2018.1063","url":null,"abstract":"","PeriodicalId":74176,"journal":{"name":"Messenger (Los Angeles, Calif. : Print)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42063183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modulation of IP3 Receptor Stability and Its Implication in Cell Death and Disease IP3受体稳定性的调节及其在细胞死亡和疾病中的意义
Messenger (Los Angeles, Calif. : Print) Pub Date : 2018-06-01 DOI: 10.1166/msr.2018.1071
Bruno Seitaj, G. Bultynck, Hristina Ivanova
{"title":"Modulation of IP3 Receptor Stability and Its Implication in Cell Death and Disease","authors":"Bruno Seitaj, G. Bultynck, Hristina Ivanova","doi":"10.1166/msr.2018.1071","DOIUrl":"https://doi.org/10.1166/msr.2018.1071","url":null,"abstract":"","PeriodicalId":74176,"journal":{"name":"Messenger (Los Angeles, Calif. : Print)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1166/msr.2018.1071","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48454572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
A Ca2+-Calmodulin-Dependent Protein Kinase II Inhibitor Suppresses Cell Migration of CD38-Expressing Human Embryonic Kidney Cells: A Preliminary Report 钙调素依赖性蛋白激酶II抑制剂抑制表达cd38的人胚胎肾细胞的细胞迁移:初步报告
Messenger (Los Angeles, Calif. : Print) Pub Date : 2018-06-01 DOI: 10.1166/MSR.2018.1064
M. Hashii, Yukie Tanaka, Y. Higuchi, Ryosuke Gabata, Makoto Tsubomoto, Noriko Iwatsuka, Mitsuyo Teramachi, T. Kamijima, S. Yokoyama, S. Matsukawa, H. Higashida
{"title":"A Ca2+-Calmodulin-Dependent Protein Kinase II Inhibitor Suppresses Cell Migration of CD38-Expressing Human Embryonic Kidney Cells: A Preliminary Report","authors":"M. Hashii, Yukie Tanaka, Y. Higuchi, Ryosuke Gabata, Makoto Tsubomoto, Noriko Iwatsuka, Mitsuyo Teramachi, T. Kamijima, S. Yokoyama, S. Matsukawa, H. Higashida","doi":"10.1166/MSR.2018.1064","DOIUrl":"https://doi.org/10.1166/MSR.2018.1064","url":null,"abstract":"","PeriodicalId":74176,"journal":{"name":"Messenger (Los Angeles, Calif. : Print)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1166/MSR.2018.1064","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43936513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The Contributions of Cd38 and Cd157 Gene Deletion in Neurobehavioral Outcomes Cd38和Cd157基因缺失对神经行为结果的影响
Messenger (Los Angeles, Calif. : Print) Pub Date : 2018-06-01 DOI: 10.1166/MSR.2018.1067
O. Lopatina, Satoka Kasai, Stanislav M. Cherepanov, Kazumi Furuhara, T. Yoshihara, A. Shabalova, M. Gerasimenko, C. Tsuji, S. Yokoyama, H. Higashida, A. Salmina
{"title":"The Contributions of Cd38 and Cd157 Gene Deletion in Neurobehavioral Outcomes","authors":"O. Lopatina, Satoka Kasai, Stanislav M. Cherepanov, Kazumi Furuhara, T. Yoshihara, A. Shabalova, M. Gerasimenko, C. Tsuji, S. Yokoyama, H. Higashida, A. Salmina","doi":"10.1166/MSR.2018.1067","DOIUrl":"https://doi.org/10.1166/MSR.2018.1067","url":null,"abstract":"","PeriodicalId":74176,"journal":{"name":"Messenger (Los Angeles, Calif. : Print)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49298888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Possible Involvement of the Dopaminergic System in Emotional Deficiency in CD157/BST1 Knockout Mice 多巴胺能系统可能参与CD157/BST1基因敲除小鼠的情绪缺陷
Messenger (Los Angeles, Calif. : Print) Pub Date : 2018-06-01 DOI: 10.1166/MSR.2018.1070
T. Yoshihara, K. Shiba, K. Ishihara, H. Higashida
{"title":"Possible Involvement of the Dopaminergic System in Emotional Deficiency in CD157/BST1 Knockout Mice","authors":"T. Yoshihara, K. Shiba, K. Ishihara, H. Higashida","doi":"10.1166/MSR.2018.1070","DOIUrl":"https://doi.org/10.1166/MSR.2018.1070","url":null,"abstract":"","PeriodicalId":74176,"journal":{"name":"Messenger (Los Angeles, Calif. : Print)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49636525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
TRPM2, a New Player, in Cyclic ADP-Ribose/CD38-Dependent Oxytocin Release in the Hypothalamus TRPM2，一个新的参与者，在下丘脑循环ADP核糖/CD38依赖性催产素释放中
Messenger (Los Angeles, Calif. : Print) Pub Date : 2018-06-01 DOI: 10.1166/MSR.2018.1068
T. Tsuji, Mingkun Liang, O. Lopatina, Teruko Yuhi, C. Tsuji, Jing Zhong, Shirin Akther, Tomoko Nishimura, S. Amina, Hong-Xiang Liu, M. Hashii, Kazumi Furuhara, Yasuhiko Yamamoto, S. Yokoyama, H. Higashida
{"title":"TRPM2, a New Player, in Cyclic ADP-Ribose/CD38-Dependent Oxytocin Release in the Hypothalamus","authors":"T. Tsuji, Mingkun Liang, O. Lopatina, Teruko Yuhi, C. Tsuji, Jing Zhong, Shirin Akther, Tomoko Nishimura, S. Amina, Hong-Xiang Liu, M. Hashii, Kazumi Furuhara, Yasuhiko Yamamoto, S. Yokoyama, H. Higashida","doi":"10.1166/MSR.2018.1068","DOIUrl":"https://doi.org/10.1166/MSR.2018.1068","url":null,"abstract":"","PeriodicalId":74176,"journal":{"name":"Messenger (Los Angeles, Calif. : Print)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1166/MSR.2018.1068","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43119491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New Insights into the Gating Mechanism of the IP3 Receptor IP3受体门控机制的新见解
Messenger (Los Angeles, Calif. : Print) Pub Date : 2018-06-01 DOI: 10.1166/msr.2018.1072
K. Hamada, K. Mikoshiba
{"title":"New Insights into the Gating Mechanism of the IP3 Receptor","authors":"K. Hamada, K. Mikoshiba","doi":"10.1166/msr.2018.1072","DOIUrl":"https://doi.org/10.1166/msr.2018.1072","url":null,"abstract":"","PeriodicalId":74176,"journal":{"name":"Messenger (Los Angeles, Calif. : Print)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1166/msr.2018.1072","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46075829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Special Section on the Sixth NAD (Asian 3) Meeting in 2017 2017年第六届NAD(亚洲)会议专题部分
Messenger (Los Angeles, Calif. : Print) Pub Date : 2018-06-01 DOI: 10.1166/msr.2018.1062
H. Higashida
{"title":"A Special Section on the Sixth NAD (Asian 3) Meeting in 2017","authors":"H. Higashida","doi":"10.1166/msr.2018.1062","DOIUrl":"https://doi.org/10.1166/msr.2018.1062","url":null,"abstract":"","PeriodicalId":74176,"journal":{"name":"Messenger (Los Angeles, Calif. : Print)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47644245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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