V.L. Wang , M. Derenoncourt , C. Brokus , J. Stevens , J. Carpenter , A. Steck , I. Kuo , J.S. Catalanotti , H. Akselrod , K. Burgan , G. Burkholder , E. Eaton , H. Masur , S. Kottilil , E. Rosenthal , S. Kattakuzhy
{"title":"Major barriers and facilitators of care for patients with infectious complications of opioid use disorder: A multi-site, qualitative analysis of expert stakeholders from the CHOICE protocol","authors":"V.L. Wang , M. Derenoncourt , C. Brokus , J. Stevens , J. Carpenter , A. Steck , I. Kuo , J.S. Catalanotti , H. Akselrod , K. Burgan , G. Burkholder , E. Eaton , H. Masur , S. Kottilil , E. Rosenthal , S. Kattakuzhy","doi":"10.1016/j.josat.2025.209778","DOIUrl":"10.1016/j.josat.2025.209778","url":null,"abstract":"<div><h3>Background</h3><div>Given the rising rates of morbidity and mortality related to Opioid Use Disorder (OUD), hospitalization may be an opportune time to engage individuals with OUD in treatment and prevention. The ‘Continuum of Care in Hospitalized Patients with Opioid Use Disorder and Infectious Complications of Injection Drug Use’ (‘CHOICE’) protocol was a multi-site study developed to understand barriers and facilitators of care for patients with infectious complications of OUD.</div></div><div><h3>Methods</h3><div>The study conducted semi-structured interviews with twenty-four stakeholders (community providers, harm reductionists, and other professionals) from CHOICE sites involved in the continuum of OUD care: Georgia, Maryland, Alabama, and the District of Columbia. The data was coded using qualitative management software (NVivo 11). Subsequent thematic analysis involved a hybrid deductive and inductive approach.</div></div><div><h3>Findings</h3><div>We identified seven key themes, organized through the lens of a Social-Ecologic (SE) Model, an analytical framework that groups themes by level of influence at the individual, institutional, community, and societal/national levels. Major findings from each theme included (1) stigmatization of patients with OUD, and their providers; (2) lack of standardization around evidence-based OUD practices; (3) limited patient and provider resources; (4) poor inter- and intra-institutional communication; (5) the importance of co-localized care and harm reduction; (6) impact of the institutional and pandemic environment; and (7) the restrictive nature of national policies.</div></div><div><h3>Conclusions</h3><div>These common findings across geographically and policy-diverse clinical sites point to a need for targeted policy, training, and clinical interventions at each SE level, and for standards in OUD care to be developed and prioritized.</div></div>","PeriodicalId":73960,"journal":{"name":"Journal of substance use and addiction treatment","volume":"178 ","pages":"Article 209778"},"PeriodicalIF":1.9,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144818547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jennifer McNeely, Katharine A Bradley, Jane M Liebschutz, Geetha A Subramaniam
{"title":"Why is substance use missing from my patient's problem list? CTN research to advance screening, prevention, and treatment of substance use in primary care.","authors":"Jennifer McNeely, Katharine A Bradley, Jane M Liebschutz, Geetha A Subramaniam","doi":"10.1016/j.josat.2025.209780","DOIUrl":"10.1016/j.josat.2025.209780","url":null,"abstract":"<p><p>While approximately one in five Americans with substance use disorder (SUD) receives treatment in addiction treatment programs, a majority have seen a primary care medical provider in the past year. Recognizing the critical role of primary care in addressing prevention and treatment of unhealthy substance use, for over a decade the National Drug Abuse Treatment Clinical Trials Network (CTN) has supported research to build the tools and evidence needed to support the integration of SUD care, while remaining realistic about the barriers to doing so. Authored by primary care and addiction medicine physician researchers, this commentary provides an overview of CTN primary care-focused research, from developing and implementing substance use screening tools to advancing evidence-based SUD treatment delivery in primary care settings. We identify three priority areas for research and practice innovations: 1) identifying effective treatment interventions to address polysubstance use; 2) improving screening and treatment for cannabis use; and 3) building the evidence base for substance use interventions among non-treatment seeking patients who have unhealthy drug use identified through screening. Addressing these areas can help primary care fulfill its potential as a key component of the substance use services continuum of care.</p>","PeriodicalId":73960,"journal":{"name":"Journal of substance use and addiction treatment","volume":" ","pages":"209780"},"PeriodicalIF":1.9,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12427610/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144812725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jon Morgenstern , Svetlana Levak , Sean P. Madden , Alexis Kuerbis , Fredrick Muench
{"title":"Evaluating telehealth and text-based interventions for at-risk drinkers: A pilot study of feasibility and efficacy","authors":"Jon Morgenstern , Svetlana Levak , Sean P. Madden , Alexis Kuerbis , Fredrick Muench","doi":"10.1016/j.josat.2025.209779","DOIUrl":"10.1016/j.josat.2025.209779","url":null,"abstract":"<div><h3>Background</h3><div>At-risk drinking refers to when individuals drink above the recommended guidelines for safe drinking without meeting criteria for severe alcohol use disorder. At-risk drinking is a prevalent, costly public health problem. Effective face-to-face brief interventions for at-risk drinking exist but are not widely available. Digital interventions hold promise to increase access to care and improve treatment for at-risk drinkers.</div></div><div><h3>Objective</h3><div>This pilot study examined the feasibility and efficacy of a fully remote digital alcohol reduction support service for at-risk drinkers.</div></div><div><h3>Methods</h3><div>Participants (N = 163; mean age = 46.2 years, 59.5 % female) were recruited via a website and could select between two 8-week interventions: alcohol adaptive text messaging (Text Support, n = 118; 72.4 %) or a hybrid intervention (Coaching, n = 45; 27.6 %) that combined a brief, alcohol behavioral telehealth therapy with digital tools.</div></div><div><h3>Results</h3><div>Participants selecting Text Support reported significantly lower levels of alcohol consumption, other indicators of alcohol severity, and were significantly more likely to endorse moderation (48.3 % versus 24.4 %) and less likely to endorse abstinence (10.2 % versus 28.9 %) as a drinking goal relative to participants selecting Coaching. Participants across conditions reported significantly reduced drinking from baseline to the end of the 8-week intervention period. However, low compliance with outcome measurement limited the efficacy evaluation.</div></div><div><h3>Conclusion</h3><div>Overall, findings support the feasibility and pilot efficacy of the hybrid intervention. In addition, findings highlight the heterogeneity of at-risk drinkers and suggest that a subgroup may prefer a fully automated digital intervention as opposed to one that includes therapist support.</div></div>","PeriodicalId":73960,"journal":{"name":"Journal of substance use and addiction treatment","volume":"178 ","pages":"Article 209779"},"PeriodicalIF":1.9,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144818546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"TOC (update)","authors":"","doi":"10.1016/S2949-8759(25)00137-7","DOIUrl":"10.1016/S2949-8759(25)00137-7","url":null,"abstract":"","PeriodicalId":73960,"journal":{"name":"Journal of substance use and addiction treatment","volume":"176 ","pages":"Article 209758"},"PeriodicalIF":1.9,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144781021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"C2: editorial board","authors":"","doi":"10.1016/S2949-8759(25)00136-5","DOIUrl":"10.1016/S2949-8759(25)00136-5","url":null,"abstract":"","PeriodicalId":73960,"journal":{"name":"Journal of substance use and addiction treatment","volume":"176 ","pages":"Article 209757"},"PeriodicalIF":1.9,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144780776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hannah S. Szlyk , Devin E. Banks , Nathaniel A. Dell , William D. Hutson , Lucy Meigs
{"title":"Something does not add up: Rethinking how we compensate for research participation among people who use drugs","authors":"Hannah S. Szlyk , Devin E. Banks , Nathaniel A. Dell , William D. Hutson , Lucy Meigs","doi":"10.1016/j.josat.2025.209774","DOIUrl":"10.1016/j.josat.2025.209774","url":null,"abstract":"<div><div>In this commentary, we draw upon the care ethics framework to discuss why and how substance use researchers should re-evaluate traditional best practices for participant compensation. We encourage researchers to have conversations with community partners and potential participants alike on how compensation can convey appreciation, whether the participants have a need for the specific type of compensation, and if participants are able to capably and conveniently use it. When planned poorly, compensation can cause harm to participants and communities and undermine research efforts. Three case examples are provided to illustrate these points. Lastly, we urge researchers to update their respective institutions about barriers to equitable compensation that may be embedded within the research infrastructure. Overall, compensation has the potential to strengthen collaborations between researchers and community members and provide a strong foundation for rigorous and impactful substance use recovery research.</div></div>","PeriodicalId":73960,"journal":{"name":"Journal of substance use and addiction treatment","volume":"177 ","pages":"Article 209774"},"PeriodicalIF":1.9,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144767143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The ethics we abandon – A medical student perspective on a familiar face","authors":"Sarah Petelinsek","doi":"10.1016/j.josat.2025.209773","DOIUrl":"10.1016/j.josat.2025.209773","url":null,"abstract":"","PeriodicalId":73960,"journal":{"name":"Journal of substance use and addiction treatment","volume":"177 ","pages":"Article 209773"},"PeriodicalIF":1.9,"publicationDate":"2025-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144757672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Miriam T.H. Harris , Megan Hall , Sylvia Ellison , JaNae Holloway , Carly Bridden , Sarah M. Bagley , Mackenzie Bullard , Deborah Chassler , Avik Chatterjee , Anindita Dasgupta , Mari-Lynn Drainoni , Dawn E. Gruss , Elizabeth Jadovich , Rachel Katz , Christine Mayotte , Jessica L. Neufeld , Emmanuel Oga , LaShawn Glasgow
{"title":"Tailored strategies to reduce opioid overdose deaths for pregnant and postpartum women: Examples and lessons learned from the HEALing Communities Study","authors":"Miriam T.H. Harris , Megan Hall , Sylvia Ellison , JaNae Holloway , Carly Bridden , Sarah M. Bagley , Mackenzie Bullard , Deborah Chassler , Avik Chatterjee , Anindita Dasgupta , Mari-Lynn Drainoni , Dawn E. Gruss , Elizabeth Jadovich , Rachel Katz , Christine Mayotte , Jessica L. Neufeld , Emmanuel Oga , LaShawn Glasgow","doi":"10.1016/j.josat.2025.209766","DOIUrl":"10.1016/j.josat.2025.209766","url":null,"abstract":"<div><h3>Introduction</h3><div>Pregnant and postpartum women (PPW) face substantial barriers to opioid use disorder (OUD) care despite overdose being a leading cause of maternal mortality in the United States. In this study, we leveraged data from the Helping End Addictions Long Term (HEALing) Communities Study (HCS), a community-engaged implementation trial aimed at reducing opioid overdose deaths, to 1) describe evidence-based practice (EBP) strategies designed to reach PPW and 2) review implementation determinants.</div></div><div><h3>Methods</h3><div>We analyzed data from 50 communities across Massachusetts, New York, and Ohio that implemented the Communities That HEAL intervention from January 2020 through December 2023. HCS community coalitions used the HCS Opioid-overdose Reduction Continuum of Care Approach (ORCCA) menu to inform the selection of overdose education naloxone distribution (OEND) and medication for OUD (MOUD) EBP strategies. We used the ORCCA tracker, an HCS tool documenting strategy selection and implementation details, to identify and summarize strategies designed for PPW. We reviewed written community action and implementation plans to analyze and summarize implementation determinants.</div></div><div><h3>Results</h3><div>The 50 communities included in this analysis selected 29 EBP strategies designed to reach PPW, and 21 (72.4 %) of the selected strategies were implemented, accounting for 3.5 % of all implemented strategies. Most (85.7 %) focused on MOUD, 31.0 % were based in rural communities, and 66.7 %, 23.8 %, and 9.5 % were delivered in healthcare sectors, behavioral health sectors, and criminal legal sectors, respectively. Barriers to implementing OUD strategies intended for PPW included a lack of staff or services with adequate experience, and stigma preventing delivery and engagement. Facilitators included leveraging existing services and community expertise to expand OUD care.</div></div><div><h3>Conclusion</h3><div>Our findings indicate a need for greater awareness of OUD among PPW and research on implementation approaches for EBPs that effectively reach this group. Leveraging existing community programs that serve PPW with substance use disorders could help expand tailored services.</div></div>","PeriodicalId":73960,"journal":{"name":"Journal of substance use and addiction treatment","volume":"177 ","pages":"Article 209766"},"PeriodicalIF":1.9,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144748826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tyler G. Erath , Rosalie LaCroix , Erin O'Keefe , Michael DeSarno , Stephen T. Higgins , Richard A. Rawson
{"title":"Interest in contingency management and reducing stimulant use among syringe service program participants","authors":"Tyler G. Erath , Rosalie LaCroix , Erin O'Keefe , Michael DeSarno , Stephen T. Higgins , Richard A. Rawson","doi":"10.1016/j.josat.2025.209763","DOIUrl":"10.1016/j.josat.2025.209763","url":null,"abstract":"<div><h3>Introduction</h3><div>Expanding access to effective treatment for stimulant use disorder (StimUD) is increasingly urgent as US fatal drug poisonings involving stimulants have rapidly increased. Limited information is available regarding interest in StimUD treatment among syringe service program (SSP) participants including interest in contingency management (CM).</div></div><div><h3>Methods</h3><div>We surveyed SSP participants in Burlington, Vermont regarding their interests in reducing and stopping stimulant use, participating in CM, and examined associations between sociodemographics, drug use, and health/treatment variables with interest in reducing and stopping stimulant use using multivariable logistic regression.</div></div><div><h3>Results</h3><div>Among 139 participants, 64.6 % reported interest in reducing and 59.7 % in stopping stimulant use. Overall, 82.8 % of participants reported interest in CM to reduce or stop stimulant use. Interest in reducing use was greater (odds ratio[95 % CI]) among participants currently receiving substance use disorder (SUD) treatment (3.84[1.61–9.14], <em>p</em> < .01), without Hepatitis C viral (HCV) infection (2.61[1.14–5.98], <em>p</em> = .02), and being somewhat (19.29[2.25–165.65], <em>p</em> = .01) or very (19.65[2.34–164.84], <em>p</em> = .01) concerned about anxiety. Interest in stopping use was greater among participants currently receiving SUD treatment (4.98[1.97–12.62], <em>p</em> < .01), without HCV infection (2.87[1.22–6.74], <em>p</em> = .02), participants whose primary drug was opioids compared to both stimulants and opioids (28.13[2.95–267.93], <em>p</em> < .01), and participants whose primary drug was stimulants compared to both stimulants and opioids (12.81[1.45–113.43], <em>p</em> = .02).</div></div><div><h3>Conclusions</h3><div>Results demonstrate interest in stimulant use treatment among this sample of SSP participants, with strong interest in CM. As community-based programs with high social acceptability for their non-judgmental services, SSPs are a novel setting to examine providing evidence-based CM for StimUD.</div></div>","PeriodicalId":73960,"journal":{"name":"Journal of substance use and addiction treatment","volume":"177 ","pages":"Article 209763"},"PeriodicalIF":1.9,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144757671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Coleen Leung , Christina Marel , Maree Teesson , Jack Wilson , Shane Darke , Paul S. Haber , Katherine L. Mills
{"title":"Correlates and predictors of PTSD among people with heroin dependence: Findings from the 18–20-year follow-up of the Australian Treatment Outcomes Study (ATOS)","authors":"Coleen Leung , Christina Marel , Maree Teesson , Jack Wilson , Shane Darke , Paul S. Haber , Katherine L. Mills","doi":"10.1016/j.josat.2025.209772","DOIUrl":"10.1016/j.josat.2025.209772","url":null,"abstract":"<div><h3>Introduction</h3><div>Cross-sectional studies have shown a well-established relationship between post-traumatic stress disorder (PTSD) and substance use disorders, particularly, heroin dependence. The present study examines the prevalence, correlates and predictors of PTSD over the longer term among people with a history of heroin dependence.</div></div><div><h3>Method</h3><div>This study explored PTSD outcomes at the 18–20-year follow-up of the Australian Treatment Outcomes Study, a prospective longitudinal study of 615 people with heroin dependence recruited from Sydney, Australia in 2001–2002. Structured interviews asked participants about demographic characteristics, drug use history and dependence, mental health and patterns of treatment seeking for heroin dependence. Group comparisons between those with and without PTSD were conducted to identify correlates of PTSD at 18–20-years. Logistic regression with backwards stepwise elimination was conducted to identify baseline predictors of PTSD at 18–20-years follow-up.</div></div><div><h3>Results</h3><div>Of the 615 people assessed at baseline, 393 provided complete PTSD data at 18–20-year follow-up. Of those, 16% met diagnostic criteria for current PTSD. Individuals with PTSD had increased odds of meeting criteria for cannabis dependence, being in current opiate treatment, experiencing a major depressive episode in the past month and lifetime suicide attempt (ORs range 1.85–4.32). Baseline predictors of PTSD at 18–20-year follow-up included female sex, a history of incarceration and current PTSD diagnosis.</div></div><div><h3>Conclusions</h3><div>This study showed PTSD remained prevalent among a cohort of people with a history of heroin dependence, and was associated with poorer long-term clinical outcomes across substance use and mental health domains. Additionally, individuals with PTSD demonstrated poorer occupational functioning and greater treatment utilisation. The finding that baseline PTSD diagnosis was a predictor of PTSD at 18–20-years stresses the need to provide effective and immediate evidence-based treatment for those with co-occurring PTSD and heroin dependence.</div></div>","PeriodicalId":73960,"journal":{"name":"Journal of substance use and addiction treatment","volume":"177 ","pages":"Article 209772"},"PeriodicalIF":1.9,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144767144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}