Journal of neuroendovascular therapy最新文献

{"title":"A Case of Coil Embolization for an Angiographically Occult Ruptured Anterior Communicating Artery Aneurysm.","authors":"Naoya Iwabuchi, Ryosuke Tashiro, Kaoru Shoji, Masayuki Ezura, Kenichi Sato, Hidenori Endo","doi":"10.5797/jnet.cr.2024-0118","DOIUrl":"10.5797/jnet.cr.2024-0118","url":null,"abstract":"<p><strong>Objective: </strong>We report a case in which coil embolization was performed for an angiographically occult ruptured anterior communicating artery aneurysm (Acom AN).</p><p><strong>Case presentation: </strong>A 91-year-old man was admitted to our hospital because of sudden deterioration of consciousness. Computed tomography (CT) revealed a diffuse subarachnoid hemorrhage in the basal cisterns, and CT angiography identified a 5-mm Acom AN. The next day, a catheter angiogram slightly visualized the neck portion of the Acom AN, despite no apparent visualization of the aneurysmal sac. We suspected intraluminal thrombosis of ruptured Acom AN, and intraaneurysmal coil embolization was performed to prevent re-rupture. By referring to the size and projection of the aneurysmal sac on CT angiography, a microcatheter was guided into the neck portion, and 3 platinum coils were successfully placed within the aneurysm without any complications. Eight days after coil embolization, recanalization of the aneurysm was suspected on magnetic resonance imaging (MRI). Another MRI obtained 17 days after coil embolization revealed gradual recanalization of the aneurysm, which was confirmed on catheter angiogram obtained 22 days after coil embolization. Additional intraaneurysmal coil embolization resulted in complete occlusion. Subsequently, the patient had an uneventful course without rebleeding and was transferred to a rehabilitation center.</p><p><strong>Conclusion: </strong>We performed intraaneurysmal coil embolization for an angiographically occult ruptured Acom AN by referencing the neck position, aneurysm projection, and aneurysm size on CT angiography. Thus, angiographically occult aneurysms can be treated with endovascular coil embolization despite the need for close follow-up studies to detect recanalization.</p>","PeriodicalId":73856,"journal":{"name":"Journal of neuroendovascular therapy","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12162250/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"World's First Artificial Intelligence-Based Evaluation of Rist Catheter Stability in Transradial Procedures: A Feasibility Study.","authors":"Shunsuke Tanoue, Yuya Sakakura, Kenichi Kono","doi":"10.5797/jnet.oa.2025-0028","DOIUrl":"10.5797/jnet.oa.2025-0028","url":null,"abstract":"<p><strong>Objective: </strong>Artificial intelligence (AI) holds promise for advancing neuroendovascular therapy through device evaluation, but its application in real-world clinical settings remains limited. We aimed to validate the feasibility of AI-based quantitative device evaluation during actual procedures by assessing the stability of the Rist radial access guide catheter (Medtronic, Dublin, Ireland), a novel device designed for the increasingly adopted transradial approach (TRA), during flow diverter stent (FDS) placement.</p><p><strong>Methods: </strong>We retrospectively analyzed 4 cases of FDS placement using Rist via the TRA. Rist was tracked in recorded fluoroscopic videos using the AI technology of Neuro-Vascular Assist (iMed Technologies, Tokyo, Japan). The movement distance of Rist during FDS placement was calculated as a stability indicator.</p><p><strong>Results: </strong>All procedures were successfully completed without any complications. Rist was introduced from the radial artery and positioned in the distal internal carotid artery. The maximum movement distances of the Rist during the procedures were 3.36, 6.63, 1.79, and 0.33 mm for each case, respectively, with an average of 3.03 mm. The maximum movement distances per minute were 1.68, 2.34, 1.19, and 0.46 mm/min, respectively, with a mean of 1.42 mm/min. These measurements suggest sufficient stability for the FDS procedures.</p><p><strong>Conclusion: </strong>This study demonstrates the feasibility of using AI technology to quantitatively analyze Rist stability in TRA procedures. To the best of our knowledge, this is the 1st clinical evaluation of device function in a clinical setting using AI technology. Further studies with more cases are required to validate these findings. This method is promising for real-world device evaluation and development.</p>","PeriodicalId":73856,"journal":{"name":"Journal of neuroendovascular therapy","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12182977/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial Intelligence in Neuroendovascular Procedures.","authors":"Kenichi Kono","doi":"10.5797/jnet.ra.2024-0107","DOIUrl":"10.5797/jnet.ra.2024-0107","url":null,"abstract":"<p><p>Recent advances in artificial intelligence (AI) have significantly transformed neuroendovascular procedures, offering innovative solutions for image analysis, procedural assistance, and clinical decision-making. This review examines the current state and future potential of AI applications in neuroendovascular interventions, focusing on 3 topics: AI-based image recognition, real-time procedural assistance, and future developments. From a research perspective, deep learning algorithms have demonstrated reasonable accuracy in vascular structure analysis and device detection, successfully identifying critical conditions such as vascular perforation, aneurysm location, and vessel occlusions. Real-time AI assistance systems may have potential clinical utility in various procedures, including carotid artery stenting, aneurysm coiling, and liquid embolization, potentially enhancing procedural safety and operator awareness. The future of AI in neuroendovascular procedures shows promise in integration with robotic systems and applications in medical education. While current systems have some limitations, ongoing technological advances suggest an expanding role of AI in enhancing procedural safety, standardization, and patient outcomes.</p>","PeriodicalId":73856,"journal":{"name":"Journal of neuroendovascular therapy","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11873741/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanical Thrombectomy for Medium-Vessel Occlusion with a Right-Sided Aortic Arch: A Case Report.","authors":"Seigo Kimura, Ryokichi Yagi, Akiko Marutani, Fumihisa Kishi, Daiji Ogawa, Keiichi Yamada, Hirokatsu Taniguchi, Masahiko Wanibuchi","doi":"10.5797/jnet.cr.2024-0094","DOIUrl":"10.5797/jnet.cr.2024-0094","url":null,"abstract":"<p><strong>Objective: </strong>A right-sided aortic arch is a rare vascular anomaly, and neuroendovascular therapy through the right-sided aortic arch is extremely rare. Herein, we report the case of a patient with a right-sided aortic arch who performed a mechanical thrombectomy for medium-vessel occlusion.</p><p><strong>Case presentation: </strong>An 84-year-old woman could not respond to her family during a conversation at 8:50 am. She was brought to our hospital at 10:30 am on the same day. A diffusion-weighted image of head magnetic resonance imaging revealed a high-intensity area in the left temporal lobe. Head magnetic resonance angiography revealed a loss of the inferior trunk of the left middle cerebral artery. A mechanical thrombectomy was performed. The guiding catheter ascended on the right side from the midline, and the patient was considered to have a right-sided aortic arch. Selecting the left common carotid artery was difficult due to its unusual origin from the ascending aorta. Internal carotid angiography revealed left temporo-occipital artery occlusion. Mechanical thrombectomy was performed using Solitaire X 3× 20 mm (Covidien, Irvine, CA, USA), and recanalization was achieved. Contrast-enhanced chest and abdominal computed tomography revealed a right-sided aortic arch with an aberrant left subclavian artery. She was transferred to a recovery hospital with a modified Rankin Scale score of 1.</p><p><strong>Conclusion: </strong>Understanding the branching patterns and classifications of the right-sided aortic arch is necessary for physicians performing mechanical thrombectomy.</p>","PeriodicalId":73856,"journal":{"name":"Journal of neuroendovascular therapy","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11851021/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143506561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Middle Meningeal Artery Embolization Does Not Confer Protection against Symptomatic Recurrence in Patients with Early Antithrombotic Therapy Following Surgery for Chronic Subdural Hematomas.","authors":"Hussein A Zeineddine, Bryden H Dawes, William W Wroe, Bronson Ciavarra, Salvatore A D'Amato, Hyun Woo Kim, Nimer Adeeb, Gabriel Galan Castro, Michael I Nahhas, Peng Roc Chen, Spiros L Blackburn, Sunil A Sheth, Ching-Jen Chen, Ryan S Kitagawa, Mark J Dannenbaum, Juan Carlos Martinez-Gutierrez","doi":"10.5797/jnet.oa.2025-0013","DOIUrl":"10.5797/jnet.oa.2025-0013","url":null,"abstract":"<p><strong>Objective: </strong>Middle meningeal artery embolization (MMAE) has emerged as a promising treatment, both as an adjunct to surgery and as a primary treatment for chronic subdural hematoma (cSDH). Here, we evaluate the efficacy of MMAE following surgery in reducing the likelihood of reoperation in patients requiring early introduction of antithrombotics.</p><p><strong>Methods: </strong>From our prospectively collected registry of patients with cSDH, we identified patients treated with surgical evacuation, either in combination with or without MMAE. Patients were included if they had a clinical indication requiring early antithrombotics within 7 days of surgery. The primary outcome was the rate of reoperation. The secondary outcomes included recurrence in midline shift or changes in cSDH width based on imaging findings.</p><p><strong>Results: </strong>Among 43 patients (53 total cSDHs) who met the inclusion criteria for the study, the median age was 71 years, 13% were female, the mean SDH thickness was 17.9 mm, and the most commonly used postoperative antithrombotic was aspirin. Sixteen cSDHs in 13 patients were treated with MMAE + surgery, while 37 cSDHs in 30 patients were treated with surgery alone. There was no difference in reoperation rates between the 2 groups (8.1% vs. 0%, surgery alone vs. surgery + MMAE, <i>p</i> = 0.55), nor in the rate of recurrence (24.3% vs. 12.5%, surgery alone vs. surgery + MMAE, <i>p</i> = 0.47).</p><p><strong>Conclusion: </strong>In this single-center cohort study, we found no clear benefit in reduced rates of reoperation or recurrence for adjunctive MMAE in patients with cSDH treated with surgical evaluation. Despite this, encouraging trends were observed in the MMAE + surgery group.</p>","PeriodicalId":73856,"journal":{"name":"Journal of neuroendovascular therapy","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12086019/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144096361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dural Arteriovenous Fistula with Shunt Restricted to the Superior Orbital Fissure: A Case Report.","authors":"Naoto Mukada, Kazuki Wakabayashi, Naoko Miyamoto, Isao Naito, Hideaki Kohga","doi":"10.5797/jnet.cr.2024-0113","DOIUrl":"10.5797/jnet.cr.2024-0113","url":null,"abstract":"<p><strong>Objective: </strong>Dural arteriovenous fistulas (DAVFs) in the superior orbital fissure (SOF) are extremely rare. We report a case of DAVF in the SOF and discuss the characteristics of angioarchitecture and the treatment strategies.</p><p><strong>Case presentation: </strong>A 72-year-old woman presented with chemosis, exophthalmos. Digital subtraction angiography revealed a right SOF DAVF mainly supplied from the accessory meningeal artery and the ophthalmic artery, which drained into the facial vein (FV) through the superior ophthalmic vein (SOV) without drainage into the cavernous sinus. A microcatheter was introduced into the shunt pouch via the FV and SOV, and coil embolization of the shunt pouch and SOV was performed, resulting in complete occlusion. However, 1 month later, DAVF recurred, with increased intraocular pressure and decreased vision. A semi-emergent transarterial glue embolization from the accessory meningeal artery was performed and complete occlusion was obtained.</p><p><strong>Conclusion: </strong>SOF DAVFs often lack cavernous sinus drainage, and transvenous embolization via the FV is recommended if FV drainage is present, but transarterial embolization may be the next treatment of choice if transvenous embolization is unsuccessful.</p>","PeriodicalId":73856,"journal":{"name":"Journal of neuroendovascular therapy","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12104572/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144152834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parent Artery Occlusion for Subarachnoid Hemorrhage due to Right Frontopolar Artery Dissection: A Case Report.","authors":"Ryota Miyake, Katsuma Iwaki, Taku Hongo, Morio Takasaki, Hideki Nakajima, Yasuhiro Fujimoto","doi":"10.5797/jnet.cr.2025-0023","DOIUrl":"10.5797/jnet.cr.2025-0023","url":null,"abstract":"<p><strong>Objective: </strong>We report a case of subarachnoid hemorrhage (SAH) due to the ruptured dissection aneurysm of the frontopolar artery (FPA), which was successfully treated with parent artery occlusion (PAO).</p><p><strong>Case presentation: </strong>A 42-year-old woman was brought to our hospital suffering from sudden severe headache and vomiting. Four days prior to admission, she experienced a mild frontal headache. Head computed tomography (CT) revealed SAH with a right medial frontal lobe hematoma. On the day of admission, we performed cerebral angiography, and a fusiform aneurysm was found in the FPA branching from the proximal right anterior cerebral artery (A1), which was suspected to be the dissection. We performed PAO for the right FPA. The patient was discharged with mRS:0 on the 27th day of admission. Several reports describe that the FPA usually bifurcate from the A2 segment, and it is rarely dissected. However, in our case, the FPA originated from the distal part of the A1 segment, and the dissection aneurysm of FPA ruptured.</p><p><strong>Conclusion: </strong>To the best of our knowledge, this is the first reported case of SAH due to a ruptured dissection aneurysm of FPA treated by PAO.</p>","PeriodicalId":73856,"journal":{"name":"Journal of neuroendovascular therapy","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12229740/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144577147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case of Flow Diverter Placement for a Recurrent Large Thrombosed Middle Cerebral Artery Aneurysm.","authors":"Yusuke Tanaka, Masato Tsuchimochi, Raisa Funatsuya, Noriaki Sekiguchi, Naoyuki Noda, Koji Suzuki, Yasuhiro Uriu, Shin Tanino, Kosuke Miyahara","doi":"10.5797/jnet.cr.2024-0088","DOIUrl":"10.5797/jnet.cr.2024-0088","url":null,"abstract":"<p><strong>Objective: </strong>There are only a few reports about flow diverter (FD) placement for large thrombosed aneurysms of the middle cerebral artery (MCA). We present a case of FD placement for a recurrent large thrombosed aneurysm of MCA at our hospital.</p><p><strong>Case presentation: </strong>A 72-year-old man with transient visual field disturbance underwent craniotomy for a large aneurysm in the left MCA; dome clipping was performed because of severe arteriosclerosis. Over several years, the residual aneurysm gradually increased in size, and despite antiplatelet therapy, the patient experienced repeated cerebral infarctions due to intra-aneurysmal thrombosis. A closer examination revealed that the M2 superior trunk was occluded. Thus, we performed FD placement, without further complications. After 6 months, the aneurysm was confirmed to be occluded with an O'Kelly-Marotta grading scale (OKM grade) of D. There was no enlargement of the thrombus inside the aneurysm, and the patient is currently under follow-up observation.</p><p><strong>Conclusion: </strong>FD placement may be an option for large thrombosed aneurysms of MCA that are difficult to treat with conventional methods.</p>","PeriodicalId":73856,"journal":{"name":"Journal of neuroendovascular therapy","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787943/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143124136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Basic Knowledge and Overview of Brain AVMs.","authors":"Michihiro Tanaka","doi":"10.5797/jnet.ra.2024-0037","DOIUrl":"10.5797/jnet.ra.2024-0037","url":null,"abstract":"<p><p>Brain arteriovenous malformations (AVMs) are intricate networks of blood vessels in which arteries connect directly to veins, bypassing the capillary system. This aberration can lead to serious neurological manifestations, including seizures, headaches, and hemorrhagic strokes. The embryonic development of AVMs implicates possible disruptions in arteriovenous differentiation during angiogenesis, improper regression of the primary capillary plexus, or the retention of fetal vasculature as contributing factors. Additionally, genetic mutations and environmental influences during pregnancy may facilitate AVM formation, with identified mutations in genes such as endoglin, activin receptor-like kinase 1, SMAD family member 4, and RAS p21 protein activator 1 disrupting vascular development. Such mutations are associated with conditions like hereditary hemorrhagic telangiectasia and capillary malformation-arteriovenous malformation syndrome, thus highlighting the essential role of genetic counseling in AVM management. This review underscores the importance of a deep comprehension of the embryological and genetic foundations of AVMs to refine diagnostic, therapeutic, and prognostic approaches. The paper advocates for advanced research on intervention strategies and emphasizes the significance of a genetics-focused approach in the clinical management of AVMs.</p>","PeriodicalId":73856,"journal":{"name":"Journal of neuroendovascular therapy","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11864997/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143525400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thrombectomy for Anterior Circulation Stroke with a Hybrid Cell Design Stent Retriever: A Multicenter Registry.","authors":"Luís Henrique de Castro-Afonso, Felipe Padovani Trivelato, Eduardo Wajnberg, Eduardo Siqueira Waihrich, Thiago Giansante Abud, Saulo Villas Boas Alves, Anderson Matsubara, Marco Tulio Salles Rezende, João Francisco Santoro Araujo, Guilherme Seizem Nakiri, Daniel Giansante Abud","doi":"10.5797/jnet.oa.2024-0083","DOIUrl":"10.5797/jnet.oa.2024-0083","url":null,"abstract":"<p><strong>Objective: </strong>Thrombectomy is the standard recanalization treatment for acute ischemic stroke (AIS) due to large vessel occlusions (LVO). However, thrombectomy was validated using a few brands of devices. New types of thrombectomy devices have been developed, and assessing their safety and efficacy is essential. This study aimed to evaluate the safety and efficacy of thrombectomy with the Aperio Hybrid stent retriever (Acandis, Pforzheim, Germany) in the treatment of patients with AIS due to anterior circulation LVO.</p><p><strong>Methods: </strong>This was a multicenter registry of thrombectomy in the treatment of stroke due to anterior circulation LVO. Between January 2022 and January 2024, a total of 128 patients were included.</p><p><strong>Results: </strong>The mean procedure time was 62 minutes. The rates of the main outcomes were recanalization (extended treatment in cerebral ischemia 2b-3) 102/128 (79.7%), symptomatic intracranial hemorrhage 9/128 (7.0%), good clinical outcome (modified Rankin Scale = 0-2) 67/128 (52.3%), and mortality 24/128 (18.7%) at 3 months.</p><p><strong>Conclusion: </strong>This study showed that, in a multicenter real-life scenario, the Aperio hybrid stent retriever was safe and effective for thrombectomy of anterior circulation strokes. The outcomes of this study were similar to those of previous large thrombectomy studies.</p>","PeriodicalId":73856,"journal":{"name":"Journal of neuroendovascular therapy","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11864990/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143525441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}