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Journal of exploratory research in pharmacology最新文献

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Hypertonic Saline and Aprotinin Inhibit Furin and Nasal Protease to Reduce SARS-CoV-2 Specific Furin Site Cleavage Activity 高渗盐水和抑酶蛋白抑制Furin和鼻腔蛋白酶降低SARS-CoV-2特异性Furin位点切割活性
Journal of exploratory research in pharmacology Pub Date : 2022-08-03 DOI: 10.14218/jerp.2021.00058
Clarissa Li, Adam W. Li
{"title":"Hypertonic Saline and Aprotinin Inhibit Furin and Nasal Protease to Reduce SARS-CoV-2 Specific Furin Site Cleavage Activity","authors":"Clarissa Li, Adam W. Li","doi":"10.14218/jerp.2021.00058","DOIUrl":"https://doi.org/10.14218/jerp.2021.00058","url":null,"abstract":"","PeriodicalId":73746,"journal":{"name":"Journal of exploratory research in pharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45176784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
LC-MS Analysis and Biological Activities of Ziziphus spina-christi L. (Christ’s Thorn, Jujube) Leaves from Tunisia Oasis 突尼斯绿洲酸枣叶的LC-MS分析及其生物活性
Journal of exploratory research in pharmacology Pub Date : 2022-07-28 DOI: 10.14218/jerp.2022.00001
M. Elaloui, B. Essghaier, H. Ghazghazi, R. Chaouachi, Salima Bahri, S. Hamdi, Rania Ben Nasr, J. M. Jemâa, Y. Ammari, A. Laamouri
{"title":"LC-MS Analysis and Biological Activities of Ziziphus spina-christi L. (Christ’s Thorn, Jujube) Leaves from Tunisia Oasis","authors":"M. Elaloui, B. Essghaier, H. Ghazghazi, R. Chaouachi, Salima Bahri, S. Hamdi, Rania Ben Nasr, J. M. Jemâa, Y. Ammari, A. Laamouri","doi":"10.14218/jerp.2022.00001","DOIUrl":"https://doi.org/10.14218/jerp.2022.00001","url":null,"abstract":"","PeriodicalId":73746,"journal":{"name":"Journal of exploratory research in pharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42470457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Transcriptomic Identification of Key Genes in Human Peripheral Blood Mononuclear Cells for the Prognosis of Sepsis 人外周血单核细胞关键基因转录组学鉴定与脓毒症预后的关系
Journal of exploratory research in pharmacology Pub Date : 2022-06-02 DOI: 10.14218/jerp.2022.00023
Yang Xiao, Yan-Jun Wang, Jian-Gang Xie, Xiao-Chuang Wang
{"title":"Transcriptomic Identification of Key Genes in Human Peripheral Blood Mononuclear Cells for the Prognosis of Sepsis","authors":"Yang Xiao, Yan-Jun Wang, Jian-Gang Xie, Xiao-Chuang Wang","doi":"10.14218/jerp.2022.00023","DOIUrl":"https://doi.org/10.14218/jerp.2022.00023","url":null,"abstract":"","PeriodicalId":73746,"journal":{"name":"Journal of exploratory research in pharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43090389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Exploring Polyphenol Based Bioactive Antioxidants of Underutilized Herb Amaranthus Spinosus L. for Medicinal Purposes 未充分利用的苋属植物多酚类抗氧化剂的药用研究
Journal of exploratory research in pharmacology Pub Date : 2022-06-02 DOI: 10.14218/jerp.2022.00012
Agnideepa Kar, S. Bhattacharjee
{"title":"Exploring Polyphenol Based Bioactive Antioxidants of Underutilized Herb Amaranthus Spinosus L. for Medicinal Purposes","authors":"Agnideepa Kar, S. Bhattacharjee","doi":"10.14218/jerp.2022.00012","DOIUrl":"https://doi.org/10.14218/jerp.2022.00012","url":null,"abstract":"","PeriodicalId":73746,"journal":{"name":"Journal of exploratory research in pharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44855231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment with Hibiscus sabdarrifa L Anthocyanins Improve Hematological Parameters in Rats Exposed to Cadmium Hibiscus sabdarifa L花青素对镉暴露大鼠血液学参数的改善作用
Journal of exploratory research in pharmacology Pub Date : 2022-05-20 DOI: 10.14218/jerp.2022.00003
O. Orororo, S. Asagba
{"title":"Treatment with Hibiscus sabdarrifa L Anthocyanins Improve Hematological Parameters in Rats Exposed to Cadmium","authors":"O. Orororo, S. Asagba","doi":"10.14218/jerp.2022.00003","DOIUrl":"https://doi.org/10.14218/jerp.2022.00003","url":null,"abstract":"","PeriodicalId":73746,"journal":{"name":"Journal of exploratory research in pharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45758375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anti-inflammatory Effects of Tabersonine in Rheumatoid Arthritis Tabersonine对类风湿性关节炎的抗炎作用
Journal of exploratory research in pharmacology Pub Date : 2022-04-29 DOI: 10.14218/jerp.2022.00013
Ruojia Zhang, Shu-Feng Li, Haojun Shi, Jian-Li Zhao, Yun Geng, H. Fan, Yuang Zhang, Dan-dan Shi, Ting Wang, Xifeng Li, Ting T. Zhang, Ji-hong Pan, Luna Ge, Jin-Xiang Han
{"title":"Anti-inflammatory Effects of Tabersonine in Rheumatoid Arthritis","authors":"Ruojia Zhang, Shu-Feng Li, Haojun Shi, Jian-Li Zhao, Yun Geng, H. Fan, Yuang Zhang, Dan-dan Shi, Ting Wang, Xifeng Li, Ting T. Zhang, Ji-hong Pan, Luna Ge, Jin-Xiang Han","doi":"10.14218/jerp.2022.00013","DOIUrl":"https://doi.org/10.14218/jerp.2022.00013","url":null,"abstract":"","PeriodicalId":73746,"journal":{"name":"Journal of exploratory research in pharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45217783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Targeting MYC to Combat Pancreatic Cancer 靶向MYC对抗胰腺癌
Journal of exploratory research in pharmacology Pub Date : 2022-04-28 DOI: 10.14218/jerp.2021.00015
Yu-hong Liu, Yi-Xiang Gan, Jun Chen, Ya-Xin Jiang, Fei Huang, D. Tang
{"title":"Targeting MYC to Combat Pancreatic Cancer","authors":"Yu-hong Liu, Yi-Xiang Gan, Jun Chen, Ya-Xin Jiang, Fei Huang, D. Tang","doi":"10.14218/jerp.2021.00015","DOIUrl":"https://doi.org/10.14218/jerp.2021.00015","url":null,"abstract":"","PeriodicalId":73746,"journal":{"name":"Journal of exploratory research in pharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48664592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ozone Therapy for Prevention and Treatment of COVID-19 臭氧疗法预防和治疗COVID-19
Journal of exploratory research in pharmacology Pub Date : 2022-04-27 DOI: 10.14218/jerp.2022.00015
Gregorio Martínez-Sánchez
{"title":"Ozone Therapy for Prevention and Treatment of COVID-19","authors":"Gregorio Martínez-Sánchez","doi":"10.14218/jerp.2022.00015","DOIUrl":"https://doi.org/10.14218/jerp.2022.00015","url":null,"abstract":"<abstract><p>The pandemic of Coronavirus Disease 2019 (COVID-19), caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2), represents an unprecedented threat to health and the world economy. According to the scientific background and preliminary clinical trials, ozone therapy (OT) may help as complementary therapy in prophylaxis, treatment, and in the recovery of convalescents. During the COVID-19 pandemic, the number of registered clinical trials using OT on COVID-19 represented an increment of 36% compared to the total number of previously recorded clinical studies. At present, papers that report an intervention in COVID-19 patients total 25. Four trials have been done in prophylaxis, there are 3 manuscripts enrolled convalescents, and there is 1 meta-analysis. Manuscripts with outcomes, indexed in the MedLine database, represent 73%. The most widely used routes of administration for the intervention in COVID-19 patients are ozonated saline solution and major autohemotherapy. Preliminary results are encouraging, indicating that OT reduces inflammation indices, decreases the time of assisted respiration, decreases C-reactive protein, improves oxygen saturation, could decrease mortality, and makes polymerase chain reaction tests negative in shorter periods. When trained medical doctors follow the correct protocols and use certified devices, the improvements that have been reported allow the patients to recover more quickly. However, it is considered that larger clinical studies are needed.</p></abstract>","PeriodicalId":73746,"journal":{"name":"Journal of exploratory research in pharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138527487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Physicochemical and in Vitro Antioxidant Properties of Juice and Cake Filters from Carissa edulis Vahl Fruits 芒果汁和滤饼器的理化和体外抗氧化性能
Journal of exploratory research in pharmacology Pub Date : 2022-04-14 DOI: 10.14218/jerp.2022.00004
Deli Kafache, Markusse Deli, B. R. T. Galani, Aurelie Solange Ntso Agume, A. A. Bouba, N. Njintang
{"title":"Physicochemical and in Vitro Antioxidant Properties of Juice and Cake Filters from Carissa edulis Vahl Fruits","authors":"Deli Kafache, Markusse Deli, B. R. T. Galani, Aurelie Solange Ntso Agume, A. A. Bouba, N. Njintang","doi":"10.14218/jerp.2022.00004","DOIUrl":"https://doi.org/10.14218/jerp.2022.00004","url":null,"abstract":"","PeriodicalId":73746,"journal":{"name":"Journal of exploratory research in pharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41325151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Role of Hridayarnava Rasa on Erythrocyte Membrane Stabilization via Na+/K+ ATPase Activity in Atherosclerosis-induced Rabbits 水仙草通过Na+/K+ atp酶活性对动脉粥样硬化家兔红细胞膜稳定的作用
Journal of exploratory research in pharmacology Pub Date : 2022-03-15 DOI: 10.14218/jerp.2021.00041
S. Chitra, R. Arunadevi, N. Sudesh, R. Ilavarasan, Devi Veeraswamy Sharmila, K. Manish
{"title":"Role of Hridayarnava Rasa on Erythrocyte Membrane Stabilization via Na+/K+ ATPase Activity in Atherosclerosis-induced Rabbits","authors":"S. Chitra, R. Arunadevi, N. Sudesh, R. Ilavarasan, Devi Veeraswamy Sharmila, K. Manish","doi":"10.14218/jerp.2021.00041","DOIUrl":"https://doi.org/10.14218/jerp.2021.00041","url":null,"abstract":"","PeriodicalId":73746,"journal":{"name":"Journal of exploratory research in pharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44257952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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