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Journal of exploratory research in pharmacology最新文献

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Medical Application of Liposomes 脂质体的医学应用
Journal of exploratory research in pharmacology Pub Date : 2023-09-04 DOI: 10.14218/jerp.2023.00002
Biswajit Basu, B. Prajapati, Ayon Dutta, Himanshu Paliwal
{"title":"Medical Application of Liposomes","authors":"Biswajit Basu, B. Prajapati, Ayon Dutta, Himanshu Paliwal","doi":"10.14218/jerp.2023.00002","DOIUrl":"https://doi.org/10.14218/jerp.2023.00002","url":null,"abstract":"Liposomes are a potential drug delivery system involving encapsulation into a phospholipid-based vesicular carrier system. In comparison with conventional delivery systems, liposomes may be advantageous due to site-specific targeting, controlled release patterns, enhance stability, and reduce associated toxicity, among other processes. Several researchers in the last decade have attempted to develop simple or modified forms of liposomes for the effective delivery of various types of therapeutic agents. This review is focused on a discussion about some of the recent literature on the medical application of liposomes. An account of the mode of action of different types of liposomes as a supporting basis for their superior therapeutic efficiency was provided. The application of liposomes in the delivery of anticancer, anti-bacterial, and anti-fungal drugs, among others, was discussed. Along with this discussion, liposomal carriers for the management of diseases related to the respiratory and nervous system were included along with a special emphasis on the outcomes of current literature. The information gathered through this review will be useful in furnishing ideas about the current status of research studies conducted on the formulation and development of liposomal carriers.","PeriodicalId":73746,"journal":{"name":"Journal of exploratory research in pharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49422748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Utilization of Ketamine for Major Depression 氯胺酮在抑郁症中的应用
Journal of exploratory research in pharmacology Pub Date : 2023-08-28 DOI: 10.14218/jerp.2023.00027
Ryan Dao, A. Aggarwal
{"title":"Utilization of Ketamine for Major Depression","authors":"Ryan Dao, A. Aggarwal","doi":"10.14218/jerp.2023.00027","DOIUrl":"https://doi.org/10.14218/jerp.2023.00027","url":null,"abstract":"","PeriodicalId":73746,"journal":{"name":"Journal of exploratory research in pharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45824443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of Ketamine Therapy in the Treatment of Refractory Major Depressive Disorder 氯胺酮治疗难治性重度抑郁症的疗效观察
Journal of exploratory research in pharmacology Pub Date : 2023-07-25 DOI: 10.14218/jerp.2023.00023
H. van Oers
{"title":"Efficacy of Ketamine Therapy in the Treatment of Refractory Major Depressive Disorder","authors":"H. van Oers","doi":"10.14218/jerp.2023.00023","DOIUrl":"https://doi.org/10.14218/jerp.2023.00023","url":null,"abstract":"","PeriodicalId":73746,"journal":{"name":"Journal of exploratory research in pharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43057387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of TRPV1 in Health and Disease TRPV1在健康和疾病中的作用
Journal of exploratory research in pharmacology Pub Date : 2023-07-18 DOI: 10.14218/jerp.2023.00013
S. Jaffal
{"title":"Role of TRPV1 in Health and Disease","authors":"S. Jaffal","doi":"10.14218/jerp.2023.00013","DOIUrl":"https://doi.org/10.14218/jerp.2023.00013","url":null,"abstract":"","PeriodicalId":73746,"journal":{"name":"Journal of exploratory research in pharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41752383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neuronal Protective Effect of Nosustrophine in Cell Culture Models 鼻营养素对细胞培养模型神经元的保护作用
Journal of exploratory research in pharmacology Pub Date : 2023-07-17 DOI: 10.14218/jerp.2023.00021
Iván Carrera, V. Lombardi, V. Naidoo, Olaia A. Martínez-Iglesias, L. Corzo, R. Cacabelos
{"title":"Neuronal Protective Effect of Nosustrophine in Cell Culture Models","authors":"Iván Carrera, V. Lombardi, V. Naidoo, Olaia A. Martínez-Iglesias, L. Corzo, R. Cacabelos","doi":"10.14218/jerp.2023.00021","DOIUrl":"https://doi.org/10.14218/jerp.2023.00021","url":null,"abstract":"","PeriodicalId":73746,"journal":{"name":"Journal of exploratory research in pharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49479882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ustekinumab in Dermatology: Approved Indications and Off-label Uses Ustekinumab在皮肤病学:批准适应症和说明书外使用
Journal of exploratory research in pharmacology Pub Date : 2023-07-14 DOI: 10.14218/jerp.2022.00044
A. Chehad, N. Boutrid, H. Rahmoune
{"title":"Ustekinumab in Dermatology: Approved Indications and Off-label Uses","authors":"A. Chehad, N. Boutrid, H. Rahmoune","doi":"10.14218/jerp.2022.00044","DOIUrl":"https://doi.org/10.14218/jerp.2022.00044","url":null,"abstract":"","PeriodicalId":73746,"journal":{"name":"Journal of exploratory research in pharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43536118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determination of Brain Distribution of Amino Acid Neurotransmitters in Pigs and Rats by HPLC-UV 高效液相色谱-紫外分光光度法测定猪和大鼠脑内氨基酸神经递质分布
Journal of exploratory research in pharmacology Pub Date : 2023-07-13 DOI: 10.14218/jerp.2023.00029
Si Meng, Mo-Huan Tang, Xue-Jiao Zhao, Zhao-Ying Liu
{"title":"Determination of Brain Distribution of Amino Acid Neurotransmitters in Pigs and Rats by HPLC-UV","authors":"Si Meng, Mo-Huan Tang, Xue-Jiao Zhao, Zhao-Ying Liu","doi":"10.14218/jerp.2023.00029","DOIUrl":"https://doi.org/10.14218/jerp.2023.00029","url":null,"abstract":"The","PeriodicalId":73746,"journal":{"name":"Journal of exploratory research in pharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48197959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neurotoxic or Protective Cannabis Components: Delta-9-Tetrahydrocannabinol (Δ9THC) and Cannabidol (CBD) 神经毒性或保护性大麻成分:delta -9-四氢大麻酚(Δ9THC)和大麻酚(CBD)
Journal of exploratory research in pharmacology Pub Date : 2023-07-12 DOI: 10.14218/jerp.2023.00017
Marilyn H. Silva
{"title":"Neurotoxic or Protective Cannabis Components: Delta-9-Tetrahydrocannabinol (Δ9THC) and Cannabidol (CBD)","authors":"Marilyn H. Silva","doi":"10.14218/jerp.2023.00017","DOIUrl":"https://doi.org/10.14218/jerp.2023.00017","url":null,"abstract":"","PeriodicalId":73746,"journal":{"name":"Journal of exploratory research in pharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43517519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nanotechnology-based Therapeutic Strategies for Dry Eye Disease 基于纳米技术的干眼病治疗策略
Journal of exploratory research in pharmacology Pub Date : 2023-07-04 DOI: 10.14218/jerp.2023.00034
A. Philip
{"title":"Nanotechnology-based Therapeutic Strategies for Dry Eye Disease","authors":"A. Philip","doi":"10.14218/jerp.2023.00034","DOIUrl":"https://doi.org/10.14218/jerp.2023.00034","url":null,"abstract":"Dry eye disease (DED) is a prevalent ocular condition affecting a significant proportion of the global population. Character-ized by disruption of tear film homeostasis, DED results in dryness, discomfort, impaired visual clarity, and potential corneal damage. Despite its severe consequences, consistently effective treatments for DED remain elusive, leaving the majority of patients with persistent symptoms. This review aims to examine recent advancements in DED therapy, emphasizing the role of nanotechnology-based delivery systems in the development of novel treatments. By harnessing the potential of cutting-edge nanotechnology, we aspire to unveil innovative therapeutic strategies that address the unmet needs of patients with DED. Furthermore, we will discuss the current challenges, limitations, and future associated with these novel nanotechnology-based therapies for managing DED.","PeriodicalId":73746,"journal":{"name":"Journal of exploratory research in pharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42835193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New Topical Treatment for Psoriasis 银屑病的新局部治疗方法
Journal of exploratory research in pharmacology Pub Date : 2023-07-04 DOI: 10.14218/jerp.2023.00015
José Miguel Ingelmo Calvo, José Ruiz Cobo, M. Allam
{"title":"New Topical Treatment for Psoriasis","authors":"José Miguel Ingelmo Calvo, José Ruiz Cobo, M. Allam","doi":"10.14218/jerp.2023.00015","DOIUrl":"https://doi.org/10.14218/jerp.2023.00015","url":null,"abstract":"© 2023 The Author(s). This article has been published under the terms of Creative Commons Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0), which permits noncommercial unrestricted use, distribution, and reproduction in any medium, provided that the following statement is provided. “This article has been published in Journal of Exploratory Research in Pharmacology at https://doi.org/10.14218/JERP.2023.00015 and can also be viewed on the Journal’s website at https://www.xiahepublishing.com/journal/jerp ”.","PeriodicalId":73746,"journal":{"name":"Journal of exploratory research in pharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47666044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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