{"title":"Deep Cancers in Uncontrolled Diabetes and Weight Loss","authors":"","doi":"10.29011/2574-7568.010117","DOIUrl":"https://doi.org/10.29011/2574-7568.010117","url":null,"abstract":"","PeriodicalId":73707,"journal":{"name":"Journal of diabetes and treatment","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42634932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Incident New Onset Diabetes after COVID-19 Infection: Results from a National Multicenter Cohort","authors":"","doi":"10.29011/2574-7568.010114","DOIUrl":"https://doi.org/10.29011/2574-7568.010114","url":null,"abstract":"","PeriodicalId":73707,"journal":{"name":"Journal of diabetes and treatment","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45704324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Role of Technology in the Performance Measure of Insulin Cold Chains","authors":"","doi":"10.29011/2574-7568.010116","DOIUrl":"https://doi.org/10.29011/2574-7568.010116","url":null,"abstract":"","PeriodicalId":73707,"journal":{"name":"Journal of diabetes and treatment","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45735839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Upregulated Serum Glycated Albumin Contributes To Early Diabetic Nephropathy Diagnosis","authors":"","doi":"10.29011/2574-7568.010115","DOIUrl":"https://doi.org/10.29011/2574-7568.010115","url":null,"abstract":"","PeriodicalId":73707,"journal":{"name":"Journal of diabetes and treatment","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44464720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retrospective Study to Assess the Effect of Telmisartan on Urine Albumin-To-Creatinine Ratio (UACR) in Indian Hypertensive Patients with Diabetes","authors":"","doi":"10.29011/2574-7568.010113","DOIUrl":"https://doi.org/10.29011/2574-7568.010113","url":null,"abstract":"","PeriodicalId":73707,"journal":{"name":"Journal of diabetes and treatment","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41325382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Natamba, I. Sekitoleko, A. Namara, S. Tumwesigire, Salome Tino, M. Mirembe, Andrew Abaasa, M. Mubiru, A. Kakande, Faridah Nansubuga, D. Zaake, Brian Agaba, Betty Nakabuye, Ben Ayiko, H. Kalema, Nekemiah Katusiime, S. Nakubulwa, M. Sekikubo, J. Milln, A. Nakimuli, Emily L Webb, M. Nyirenda
{"title":"The Burden and Risk Factors of Hyperglycaemia in Pregnancy in Uganda: A Cross-Sectional Study","authors":"B. Natamba, I. Sekitoleko, A. Namara, S. Tumwesigire, Salome Tino, M. Mirembe, Andrew Abaasa, M. Mubiru, A. Kakande, Faridah Nansubuga, D. Zaake, Brian Agaba, Betty Nakabuye, Ben Ayiko, H. Kalema, Nekemiah Katusiime, S. Nakubulwa, M. Sekikubo, J. Milln, A. Nakimuli, Emily L Webb, M. Nyirenda","doi":"10.29011/2574-7568.010112","DOIUrl":"https://doi.org/10.29011/2574-7568.010112","url":null,"abstract":"Aims: Hyperglycaemia in pregnancy (HIP) is a major determinant of maternal and offspring adverse outcomes, but there are little data from sub-Saharan Africa. This study examined the burden and risk factors of HIP in Uganda. Materials and Methods: We collected data sociodemographic, anthropometric and clinical data from approximately 4000 pregnant women attending antenatal clinics in Uganda. Oral glucose tolerance test performed at 24-28 weeks gestation to screen for hyperglycaemia. Prevalence was defined as the number of participants diagnosed with HIP as a proportion of the total number of participants enrolled into the study, during the study period. Univariable and multivariable Poisson regression models were fitted to calculate prevalence ratios for association between risk factors and the outcome. Results: Using the 2013 WHO criteria, 8.5% (95% CI: 7.7-9.4%) of the women had HIP. In multivariable analyses, older maternal age (>30 years) and mid-gestation obesity were the key factors associated with hyperglyceamia; other factors, such as HIV infection, were less important. Conclusions: This study reveals a high prevalence of HIP in Uganda, with obesity an important contributor. Cost-effective interventions are urgently needed to mitigate this major health threat in Africa, where the rates of obesity are increasing.","PeriodicalId":73707,"journal":{"name":"Journal of diabetes and treatment","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48907686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exploring the Potential Health Benefits of Plants and Fruits Traditionally Consumed in the Yucatan Peninsula","authors":"","doi":"10.29011/2574-7568.010111","DOIUrl":"https://doi.org/10.29011/2574-7568.010111","url":null,"abstract":"","PeriodicalId":73707,"journal":{"name":"Journal of diabetes and treatment","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44006249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Variation in Glycemic and Extra Glycemic Parameters with Initiation of Remogliflozin Etabonate in Patients of T2DM Having a Good Glycemic Control with other SGLT2 Inhibitors","authors":"","doi":"10.29011/2574-7568.010110","DOIUrl":"https://doi.org/10.29011/2574-7568.010110","url":null,"abstract":"","PeriodicalId":73707,"journal":{"name":"Journal of diabetes and treatment","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45476239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohd., Y. Bajuri, Zalizawati Zainol, Raja Zahratul Azma Raja, Sabudin, A. Gafor, N. Sukor, Joerg Flemmig, Friedrich-Wilhelm Kuehne
{"title":"Redox-active clearance of Highly Glycated RBCs: A new Frontier for the Treatment of Diabetic Vasculopathies","authors":"Mohd., Y. Bajuri, Zalizawati Zainol, Raja Zahratul Azma Raja, Sabudin, A. Gafor, N. Sukor, Joerg Flemmig, Friedrich-Wilhelm Kuehne","doi":"10.29011/2574-7568.010109","DOIUrl":"https://doi.org/10.29011/2574-7568.010109","url":null,"abstract":"Objective On the global scale, 24-54% of the diabetic patients do not reach Quality Assurance (QA) target hemoglobin A1c (HbA1c) values, despite Standard of Care (SOC) treatment with glucose-lowering drugs. An alternative approach to lower highly glycated Red Blood Cells (RBCs) directly is needed to reduce the risk for development of diabetic vascular complications. HbA1c > 7.0% (53.0 mmol/mol) is associated with increasing incidence of vascular pathologies and inflammation. We tested an alternative approach to avoid pathological effects of excess glycation via direct redox-active clearance of highly glycated Red Blood Cells (RBCs) with the objective to rapidly terminate the trigger of endothelial damage and thereby to reduce the risk for development/ progression of diabetic vascular complications. We report results from a controlled clinical trial in 20 patients with high HbA1c, elevated Neutrophil-Lymphocyte Ratio (NLR) values and diabetic foot ulcer (DFU), using the chlorite-based drug WF10. HbA1c was observed, with 83% of the patients achieving HbA1c ≤ 7.0% (53.0 mmol/ mol), versus 25% in the SOC group. Lowering HbA1c to Fasting Blood Sugar- (FBS-) ratios and changes in hematological markers indicate a removal of highly glycated, pre-hemolytic RBCs by the drug. In patients with peripheral artery disease (PAD), mean Ankle Branchial Index- (ABI-) values improved from 0.83 to 1.01. The median","PeriodicalId":73707,"journal":{"name":"Journal of diabetes and treatment","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49445257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Increase in Outpatient Visits for New-Onset Type 2 Diabetes in Alabama Youth during the COVID-19 Pandemic","authors":"","doi":"10.29011/2574-7568.010107","DOIUrl":"https://doi.org/10.29011/2574-7568.010107","url":null,"abstract":"","PeriodicalId":73707,"journal":{"name":"Journal of diabetes and treatment","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44413230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}