Journal of dentistry and oral epidemiology最新文献_第3页

Comparison Between Preoperative Inflammation Based Scores and TNM Staging in Patients with Oral Cancer 口腔癌患者术前炎症评分与TNM分期的比较

Journal of dentistry and oral epidemiology Pub Date : 2022-07-11 DOI: 10.54289/jdoe2200104

Bhargav Ram

{"title":"Comparison Between Preoperative Inflammation Based Scores and TNM Staging in Patients with Oral Cancer","authors":"Bhargav Ram","doi":"10.54289/jdoe2200104","DOIUrl":"https://doi.org/10.54289/jdoe2200104","url":null,"abstract":"Abstract Background: India, one of the countries with the highest incidence of oral cancer, accounting for 30% of all new oral cancer cases in the world. Therefore, strong diagnostic markers are critical for the diagnosis and survival of patients suffering from oral cancer. Based on this relationship between inflammation and cancer progression, several inflammation-based scores have been demonstrated to have diagnostic and prognostic value in many types of malignant solid tumours. Objective: To compare the correlation between systemic inflammation based prognostic scores and tumour node metastasis (TNM) stage in patients undergoing oral cancer treatment. Methods: The inflammation-based scores were calculated for 120 patients with oral squamous cell carcinoma divided into four groups based on TNM staging. Neutrophil lymphocyte ratio (NLR), platelet lymphocyte ratio (PLR), tumour size, nodes involved were analysed. Statistics were performed to compare the diagnostic value of the selected scores and TNM stage. Results: This current study compares 30 patients in each stage of TNM stages 1,2,3 and 4. The mean tumour size is 1.8 x 1.41, 3.23x2.28, 2.85x2.43 and 3.78x 3.06 in stage 1,2,3 and 4 respectively. The largest lymph node measurable was 1.33x1.36 in stage 3 and 1.84x 1.38 in stage 4. The number of lymph nodes involved in stage 3 are 1.1 and 2.82 in stage 4. The mean NLR in stage 1,2,3 and 4 were 2.68, 2.72, 3.17 and 3.68 respectively. The mean PLR in stage 1, 2,3 and 4 were 106.4, 117.8, 108.2 and 182.2 respectively. Conclusion: The present study indicates that elevated NLR and PLR values are associated with advanced stages of TNM staging for Oral squamous cell carcinoma.","PeriodicalId":73703,"journal":{"name":"Journal of dentistry and oral epidemiology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47039071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of Periodontal Disease Status in Acute Leukemia (Myeloid and Lymphoblastic) Greek Patients: A Case - Control Study 希腊急性白血病(髓性和淋巴细胞性)患者牙周病状况的调查:一项病例对照研究

Journal of dentistry and oral epidemiology Pub Date : 2022-05-31 DOI: 10.54289/jdoe2200103

N. Chrysanthakopoulos

{"title":"Investigation of Periodontal Disease Status in Acute Leukemia (Myeloid and Lymphoblastic) Greek Patients: A Case - Control Study","authors":"N. Chrysanthakopoulos","doi":"10.54289/jdoe2200103","DOIUrl":"https://doi.org/10.54289/jdoe2200103","url":null,"abstract":"Objectives: Oral manifestations in acute leukemia patients is a serious medical condition. The aim of the current research was to compare the periodontal condition in a group of acute, myeloid and lymphoblastic, leukemia (AM/ALL) patients with a control group of healthy individuals. Methods: 98 patients with AM/ALL and 196 controls were selected. The clinical measurements used to diagnose periodontal condition concerned probing depths (PPDs), clinical attachment loss (CAL), gingival index (GI), bleeding on probing (BOP), and oral hygiene habits. The models of chi-square test and logistic regression were used to assess the possible differences between AM/ALL patients and controls. Results: The mean ages were 65.7 ± 3.4 years and 66.2 ± 2.8 years for cases and controls, respectively. AM/ALL patients had worst periodontal parameters such as PPD (p = 0.052, OR =1.725, 95% CI = 0.995-2.00), tooth-brushing frequency (p = 0.046, OR = 0.581, 95% CI = 0.341-0.00), GI (p = 0.091, OR = 1.632, 95% CI = 0.924-2.88), and BOP (p = 0.011, OR = 2.05, 95% CI = 1.18-3.563), after adjustment for smoking, socio-economic and educational status, compared with healthy individuals. Conclusion: Individuals with AM/ALL presented deeper periodontal pockets than healthy controls, worse gingival inflammation, and bleeding on probing than healthy controls and poor oral hygiene practices such as daily tooth brushing.","PeriodicalId":73703,"journal":{"name":"Journal of dentistry and oral epidemiology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42978075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Use of a New Clinical Reasoning Framework to Facilitate The Assessment and Management of Temporomandibular Disorders 使用一种新的临床推理框架来促进颞下颌疾病的评估和管理

Journal of dentistry and oral epidemiology Pub Date : 2022-03-02 DOI: 10.54289/jdoe2200101

Alexander Weden

引用次数: 0

Effect of Bone Remodeling on Dental Implant Fatigue Limit Predicted Using 3D Finite Element Analysis. 三维有限元分析预测骨重塑对种植体疲劳极限的影响。

Journal of dentistry and oral epidemiology Pub Date : 2022-01-01 DOI: 10.54289/jdoe2200102

Megha Satpathy, Yuanyuan Duan, Logan Betts, Matthew Priddy, Jason A Griggs

{"title":"Effect of Bone Remodeling on Dental Implant Fatigue Limit Predicted Using 3D Finite Element Analysis.","authors":"Megha Satpathy, Yuanyuan Duan, Logan Betts, Matthew Priddy, Jason A Griggs","doi":"10.54289/jdoe2200102","DOIUrl":"https://doi.org/10.54289/jdoe2200102","url":null,"abstract":"Background: To evaluate the effect of bone remodelling around a reduced-diameter dental implant on its fatigue limit using finite element analysis (FEA).Methods: A dental implant assembly, which included a reduced-diameter dental implant (Biomet-3i external hex), an abutment (GingiHue®) and a connector screw (Gold-Tite Square screw), was scanned using micro-computed tomography (Skyscan 1172). Its dimensions were measured using Mimics (Materialise) and an optical microscope (Keyence). The digital replicas of the physical specimens were constructed using SOLIDWORKS (Dassault Systems). A cylindrical bone specimen holder with two layers (cortical and cancellous bone) was designed in SOLIDWORKS. Two assemblies were created: (a) Model 1: Having non-remodelled bone; (b) Model 2: Cancellous bone remodelled at the regions adjacent to the implant screw threads. FEA was performed in ABAQUS (SIMULIA). In Model 1, the Young's modulus of cortical and cancellous bone were 20 GPa and 14 GPa, respectively. For Model 2, the region of the cancellous bone adjacent to the implant screw threads was assigned a Young's modulus of 20 GPa. fe-safe (SIMULIA) was used to estimate the fatigue limit.Results: The maximum von Mises stress under 100 N load was 439.9 MPa for both models 1 and 2 and was located at the connector screw. The fatigue limit was 116.4 N for both models 1 and 2.Conclusions: The results suggest that implant fatigue resistance tested according to ISO 14801 may be accurately predicted without bothering to simulate the non-homogeneous stiffness that occurs at the bone-implant interface in the clinical case.","PeriodicalId":73703,"journal":{"name":"Journal of dentistry and oral epidemiology","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968486/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10859853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

The Effect of Premedication with Curcumin on Post-Operative Pain in Single Visit Endodontic Treatment of Acute Pulpitis in Mandibular Molars: A Randomized Controlled Trial 姜黄素预用药对下颌磨牙急性牙髓病单次正畸治疗术后疼痛的影响：一项随机对照试验

Journal of dentistry and oral epidemiology Pub Date : 2021-12-25 DOI: 10.54289/jdoe2100111

Ghada El Hilaly Mohamed Eid

{"title":"The Effect of Premedication with Curcumin on Post-Operative Pain in Single Visit Endodontic Treatment of Acute Pulpitis in Mandibular Molars: A Randomized Controlled Trial","authors":"Ghada El Hilaly Mohamed Eid","doi":"10.54289/jdoe2100111","DOIUrl":"https://doi.org/10.54289/jdoe2100111","url":null,"abstract":"Objective: The purpose of this randomized double-blind clinical trial was to compare the effect of a single pretreatment dose of Curcumin and placebo on post-operative pain for patients diagnosed with symptomatic irreversible pulpitis in mandibular molars treated in single visit. Methods: Forty-four patients with severe to moderate pain randomly received either Curcumin (400mg +20 mg pepper) or placebo (420 mg Starch) one hour before starting root canal treatment (n = 22 per group). Participants rated their pain using visual analogue pain scale (VAS): preoperatively and at 5 time points: immediately post-operative, 8, 12, 24 and 48 hours postoperative. Patients also stated emergency analgesic intake. The need for supplemental anesthesia during treatment was recorded. Mann-Whitney U-test compared the two groups at each time point, while Repeated-Measure ANOVA and Wilcoxon Signed Rank test compared time points within each group. A p-value <0.05 was considered statistically significant. Results: Baseline characteristics of both groups showed non-significant differences (P > 05). Curcumin group at 8, 12 and 24 hours revealed statistically significantly less VAS values (44.2, 26.7, 19.1) than the placebo (58.5, 43.3, 30.3), respectively, (P > 05). All patients in Curcumin group did not need emergency analgesics. Curcumin group revealed statistically significantly lower percentages for the need of supplemental anesthesia (27.3%) compared to placebo (68.2%), (P < 05). Conclusion: Single preoperative oral dose of Curcumin proved to be an effective premedication that reduced post-operative pain as well as the need of supplemental anesthesia for patients diagnosed with symptomatic irreversible pulpitis of mandibular molars.","PeriodicalId":73703,"journal":{"name":"Journal of dentistry and oral epidemiology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49056953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Abutment and Orthodontics for Endurance of Dental Crowns 基台与正畸对牙冠耐久性的影响

Journal of dentistry and oral epidemiology Pub Date : 2021-12-20 DOI: 10.54289/jdoeop1

Ramya Chowdary

引用次数: 0

Treatment with Oral Appliances in Obstructive Sleep Apnea 阻塞性睡眠呼吸暂停患者口腔辅助器具的治疗

Journal of dentistry and oral epidemiology Pub Date : 2021-12-10 DOI: 10.54289/jdoe2100108

Palak Srivastava

引用次数: 0

What do Patients Use for Treating Their Oral Ulcers? And How do these Treatments Affect Their Quality of Life? 病人用什么治疗口腔溃疡?这些治疗如何影响他们的生活质量?

Journal of dentistry and oral epidemiology Pub Date : 2021-12-07 DOI: 10.54289/jdoe2100109

Ayat Gamal-AbdelNaser

{"title":"What do Patients Use for Treating Their Oral Ulcers? And How do these Treatments Affect Their Quality of Life?","authors":"Ayat Gamal-AbdelNaser","doi":"10.54289/jdoe2100109","DOIUrl":"https://doi.org/10.54289/jdoe2100109","url":null,"abstract":"Objectives: Oral ulceration forms a major category of oral lesions. Due to its effect on the quality of life, the patients seek treatment using various substances. This study investigated the types of treatments used by a sample of patients having all types of oral ulcers and its positive and negative effects on the patients' lives. Methods: This cross-sectional study included patients having different types of oral ulcers. Participants provided information about their previous treatments, the source of recommendation of its use and side effects linked to them. They filled the oral health impact profile-14 questionnaire to report the change in their quality of life after treatment. The patients' educational and social levels were tested as predictors for the use of non-conventional treatments. Results: Correct pharmaceutical treatments were administered y 34% of the participants; the most effective of which were systemic and topical steroids by ulcerative oral lichen planus patients; and vitamin supplements in recurrent aphthous stomatitis patients. The majority (64.2%) of the previously treated patients used non-conventional treatments, the most widely used of which was Tahini. Half of the patients using non-conventional treatments suffered side effects. The source of information of the self-medication was attributed mainly to the patients themselves, followed by friends and family members. Conclusion: This study reflects the widely spread habit of self-medication in our sample of patients having oral ulcers. It highlights the negative influence of these remedies.","PeriodicalId":73703,"journal":{"name":"Journal of dentistry and oral epidemiology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46110028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Does the Use of Botulinum Toxin Reduce the Intensity of Myofascial Pain in Adult Patients? A Systematic Review and Meta-Analysis 肉毒杆菌毒素的使用能减轻成年患者的肌筋膜疼痛强度吗？系统综述与荟萃分析

Journal of dentistry and oral epidemiology Pub Date : 2021-11-27 DOI: 10.54289/jdoe2100107

L. Wambier

{"title":"Does the Use of Botulinum Toxin Reduce the Intensity of Myofascial Pain in Adult Patients? A Systematic Review and Meta-Analysis","authors":"L. Wambier","doi":"10.54289/jdoe2100107","DOIUrl":"https://doi.org/10.54289/jdoe2100107","url":null,"abstract":"Objective: A systematic review was performed to evaluate if the use of botulinum toxin was able to reduce the intensity of myofascial pain compared to other treatments in adult patients. Material and Methods: A comprehensive search was carried out in the MEDLINE via Pub-Meb, Scopus, Web of Science, LILACS, BBO and Cochrane Library. In addition, the gray literature was also researched. The risk of bias tool from the Cochrane Collaboration was used by two independent reviewers for quality assessment of the studies. Results: A total of 4372 studies were identified, 9 remained in qualitative study, 8 of these studies were considered at “unclear” risk of bias and just one study was “low” risk of bias in the key domains. Only two studies presented similar data to be included in the meta-analysis. Both studies evaluated the pain relief used the botulinum toxin (BTX-A) versus saline solution. The meta-analysis demonstrated that after 3 months follow-up the pain relief was 15.70 (95 % confidence interval [CI] = 0.80 to 30.61; p = 0.04). Conclusion: The BTX-A reduced the intensity of myofascial pain compared to saline solution in adults after 3 months. However, further studies should be conducted to corroborate this finding.","PeriodicalId":73703,"journal":{"name":"Journal of dentistry and oral epidemiology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43800511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PEEK as a Potential Material for Dental Implants and its Biomechanical Properties and Osteoblast Cell Response 聚醚醚酮作为牙种植体的潜在材料及其生物力学性能和成骨细胞反应

Journal of dentistry and oral epidemiology Pub Date : 2021-11-23 DOI: 10.54289/jdoe2100106

Randall S. Williamson

{"title":"PEEK as a Potential Material for Dental Implants and its Biomechanical Properties and Osteoblast Cell Response","authors":"Randall S. Williamson","doi":"10.54289/jdoe2100106","DOIUrl":"https://doi.org/10.54289/jdoe2100106","url":null,"abstract":"Proper osseointegration is crucial for the success of dental and orthopedic implants. Titanium-6Aluminum-4Vanadium (TAV) is one of the most popular implant materials; however, polyetheretherketone (PEEK) has gained the interest of implant researchers and manufacturers over the past several years due to its lower modulus of elasticity compared to metallic implant materials. Porosity and patterned surface morphologies are thought to improve mechanical interlocking and play an important role in the differentiation of pre-osteoblasts into mature osteoblasts. This study aimed to determine the effects a macro patterned PEEK surface has on the material’s mechanical properties and the proliferation, differentiation, and maturation of pre-osteoblasts. Mechanical testing data indicated that the macro patterning improved the mechanical interlocking and has no detrimental effect on compression strength. DNA data and live/dead imaging showed that pre-osteoblasts on solid PEEK specimens did not readily differentiate but instead encouraged proliferation only. However, ALP data in comparison to the DNA data showed that cells on patterned PEEK specimens more readily entered the differentiation pathway to mineralization. This is further confirmed by the patterned PEEK specimens showing an overall higher amount of cell mineralization. Clinical significance: This study concludes that surface macro patterning of PEEK material increases the mechanical interlocking and enhances the osseointegration capability without diminishing mechanical properties.","PeriodicalId":73703,"journal":{"name":"Journal of dentistry and oral epidemiology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44256915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0