{"title":"Dermoscopic features of Clear Cell Acanthoma: A Case Report and Review of the Literature","authors":"Moustaide K, A. N, Gallouj S, Mernissi Fz","doi":"10.46619/joccr.2019.2-1048","DOIUrl":"https://doi.org/10.46619/joccr.2019.2-1048","url":null,"abstract":"Clear cell acanthoma is an uncommon type of benign epithelial tumor. Typically, it is a solitary lesion found on the lower limbs. It presents as a nodule or small plaque with slow and well-defined growth. Diagnosis used to be clinical and histopathological, but the advent of dermoscopy has led to an increase in diagnostic accuracy. We describe a case in which dermoscopy proved highly useful for diagnosis of the lesion.","PeriodicalId":73665,"journal":{"name":"Journal of clinical cases & reports","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85279966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Benzodiazepine Intoxication in a Neonate by Maternal Use in Pregnancy","authors":"Bittmann S, Villalon G, Weissenstein A, Luchter E","doi":"10.46619/joccr.2019.2-1050","DOIUrl":"https://doi.org/10.46619/joccr.2019.2-1050","url":null,"abstract":"The abuse of benzodiazepines by pregnant women can cause intoxication in the neonate. Benzodiazepines can diffuse readily across the placenta to the fetus because of their high lipid solubility. After the sixth month of pregnancy, the loss of the cytotrophoblasts from the placenta further facilitates the transport of benzodiazepines across the placenta. They may persist for at least a week in pharmacologically active concentrations after administration of high dosages to the mother. We report about a floppy, drowsy and pulmonary impaired newborn delivered in the 36th week of gestation. The mother was a regular user of clorazepate, a long-acting benzodiazepine during pregnancy.","PeriodicalId":73665,"journal":{"name":"Journal of clinical cases & reports","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76973084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Artificial Intelligence (AI) in Drug Discovery and Medicine","authors":"Ahuja Varun","doi":"10.46619/joccr.2019.2-1043","DOIUrl":"https://doi.org/10.46619/joccr.2019.2-1043","url":null,"abstract":"Artificial intelligence (AI) is a branch of computer science that deals with the development of algorithms that seek to simulate human intelligence. The phrase “artificial intelligence” was likely coined during a conference at Dartmouth College in 1956. The earliest work of medical AI dates back to the early 1970s. Over years, AI has found implications in various fields. In this article, we summarize its applications in drug discovery and medicine.","PeriodicalId":73665,"journal":{"name":"Journal of clinical cases & reports","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86670373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Physiotherapy Management in Patient with Knee Osteoarthritis through Three Tract Reasoning: A Case Report","authors":"Begum Rabea, Anwar Mohammad","doi":"10.46619/joccr.2019.2-1045","DOIUrl":"https://doi.org/10.46619/joccr.2019.2-1045","url":null,"abstract":"Background: Knee Osteoarthritis is the most common joint disorder and one of the leading causes of disability. The main symptoms associated with osteoarthritis are pain, discomfort, limitation of activity and reduced participation. Physiotherapy management is evidence-based treatment approach that have short-term and long-term effect on reducing pain, improve muscle strength and function. Aim: The aim of this study was to find out evidence-based physiotherapy in patient with knee osteoarthritis through three tract reasoning on reducing pain, improve muscle strength and function. Method: A case-based study was conducted. The three tract reasoning: procedural, interactive and conditional were used during diagnosis and in management of knee osteoarthritis. Results: The patient respond well in physiotherapy treatment. The swelling was 100% reduced, reduced pain in VAS from 8/10 to 1/10, improved muscle strength by oxford muscle grading scale by grade V, weight bearing is more (90%) and only 25% remain limitation in functionally from 69%. Conclusion: Knee osteoarthritis is frequent musculoskeletal condition that affect person’s activities and restricted the participation. Using clinical reasoning physiotherapist diagnosed and managed the symptoms. After receiving physiotherapy treatment improved the patient’s status of health.","PeriodicalId":73665,"journal":{"name":"Journal of clinical cases & reports","volume":"257 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79119926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Physio Kundalini Syndrome: A Case Report","authors":"Jose Carvalho Ramos Alexandre","doi":"10.46619/joccr.2019.2-1040","DOIUrl":"https://doi.org/10.46619/joccr.2019.2-1040","url":null,"abstract":"With the spread of yoga, meditation, and other Eastern spiritual practices in Western countries, clinical cases of “physio kundalini syndrome” have begun to emerge. In this article I presented a case that, despite having common elements with a psychotic disorder, can be considered a typical clinical case of awakening of kundalini, since the patient was apparently able to solve his health problems without any medical intervention and says he is perfectly integrated into the community.","PeriodicalId":73665,"journal":{"name":"Journal of clinical cases & reports","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75071694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Emmanuel, A. U. Akpan, Ohwonigho Collins Adjekuko, E. Obeagu
{"title":"Analysis of Erythrocyte Indices of Children in Internally Displaced People Camp of Yola, Northeast Nigeria","authors":"A. Emmanuel, A. U. Akpan, Ohwonigho Collins Adjekuko, E. Obeagu","doi":"10.46619/joccr.2019.2-1042","DOIUrl":"https://doi.org/10.46619/joccr.2019.2-1042","url":null,"abstract":"Background/Objectives: Erythrocyte indices constitute important parameters useful in clinical care of children. Analysis of erythrocyte indices for children in IDP (Internally Displaced People) camps in Adamawa State like in most states in Nigeria was not fully studied. Therefore, this study aims to analyze the erythrocyte indices of children in Fufore IDP camp in Yola. Materials and Methods: This study enrolled 297 children (137 females and 160 males) in the camp with age range of 12 to 61 months old and 201 apparently healthy school children as control group. 3ml of blood were collected from children and transferred into K3-EDTA vacutainer tubes. Full blood count was determined within four hours of blood collection using the Sysmex XP300 hematological analyzer. Results: Mean erythrocyte count of subjects and control was 3.1 ± 0.7 X109/l and 4.3 ± 0.7 X109/l respectively at P<0.05 and red cell distribution width (RDW) of subjects was 16.9% while that of control was 13.5%. Hemoglobin level of subject and control was 9.7 ± 1.1 g/dl and 12.4 ± 1.3 g/dl respectively. The mean Pack Cell Volume (PCV) of subjects was 32.7 ± 0.3% while the PCV of control group was 37.0 ± 0.2%. The Mean Cell Volume (MCV) of subject and control group was 74.8 ± 0.6 fl and 81 ± 0.5 fl respectively while Mean Cell Hemoglobin (MCH) of the control and subject group was 26.9 ± 0.9 pg and 27 ± 0.4 pg respectively at P<0.05. Conclusion: Children in IDP camp had lower RBC count, PCV, MCV, Hemoglobin values and higher RDW value than the control group at P<0.05. Hence microcytic and iron deficiency anemia was observed among children in Fufore IDP camp in Yola.","PeriodicalId":73665,"journal":{"name":"Journal of clinical cases & reports","volume":"60 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79333175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Case Report of Obsessive-Compulsive Disorder and Complete Remission of Schizophrenia","authors":"Shamima Nur Nusrat, Hasan Bin Rakib Kabirul","doi":"10.46619/joccr.2019.2-1039","DOIUrl":"https://doi.org/10.46619/joccr.2019.2-1039","url":null,"abstract":"A 21-year-old lady who is previously diagnosed as a case of Schizophrenia, 4 years back, with positive symptoms such as delusion, hallucination. She has prescribed with risperidone 4 mg and she is compliant to drug. Currently she is on full remission for 1 year. She is under treatment with Risperidon, 4 mg. This lady has some complaints of obsessions such as aggressive impulses and pathological doubt which is followed by some compulsions such as avoidance and checking rituals for last 3 years. She has complained of having some experiences such as doing something embarrassing and these experiences are truly intrusive, unwanted and senseless to her. This currently remitted Schizophrenic patient has good insight now. She has a marked improvement in her daily activities as well as sociability.","PeriodicalId":73665,"journal":{"name":"Journal of clinical cases & reports","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80531979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Neurological Decompensation of an Old Ischaemic Stroke following Infection","authors":"Imran Muhammad","doi":"10.46619/joccr.2019.2-1034","DOIUrl":"https://doi.org/10.46619/joccr.2019.2-1034","url":null,"abstract":"Early neurological deterioration is a well-established complication of an acute ischaemic stroke, however late deterioration is an uncommon finding and could be very challenging to diagnose and treat in timely manner. I report a case of an 82-year-old male who had suffered a stroke 28 years earlier and was functionally performing very well afterwards and living independently. This patient was presented to Worcestershire Hospital with signs and symptoms consistent with Urinary Tract Infection diagnosis. He was treated with Trimethoprim and his clinical condition improved significantly. While awaiting for his social rehab he suddenly developed dysphonia and dysphagia, along with mixed upper and lower motor neuron lesion signs consistent with a posterior circulation stroke. He was investigated extensively and MRI spine ruled out any spinal cord compression however MRI head revealed old infarcts in left parietal lobe, cerebellar region and thalamic area (no acute changes). Surprisingly MRI head also shown global atrophic change with significant atrophy of midbrain in comparison to the pons (Hummingbird sign) which rose suspicion of progressive supranuclear palsy. Initially patient was treated for acute stroke as per stroke team advice however patient was later reviewed by neurologist who explained that symptoms were attributed due to neurological decompensation of chronic infarcts (left parietal, thalamic, cerebellar) exacerbated by acute infection. Progressive Supranuclear Palsy was also excluded based on sudden onset of symptoms as compared to gradual onset of actual disease. His neurological symptoms improved slowly, but the dysphagia and dysphonia persisted. The risk of aspiration pre-empted the insertion of a percutaneous endoscopic gastrostomy (PEG) for feeding before he was discharged for rehabilitation.","PeriodicalId":73665,"journal":{"name":"Journal of clinical cases & reports","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87605002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Seminomas in the Elderly: A Rare Situation but a Challenging Problem","authors":"L. Daniel, Landis Michael, Trieu Becca","doi":"10.46619/joccr.2019.2-1037","DOIUrl":"https://doi.org/10.46619/joccr.2019.2-1037","url":null,"abstract":"While typically a disease of younger men, seminomas do occasionally occur beyond the age of 70. There is less clarity on the treatment for men in this age range. Herein we describe a case of a man in his 80s with aggressive disease, review available literature, and highlight the challenges of treatment men in this age range.","PeriodicalId":73665,"journal":{"name":"Journal of clinical cases & reports","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90197454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Real Origin of Alice in Wonderland Syndrome in Childhood is still Unknown: Does Physical Abuse Play a Major Role?","authors":"B. Stefan","doi":"10.46619/joccr.2019.2-1036","DOIUrl":"https://doi.org/10.46619/joccr.2019.2-1036","url":null,"abstract":"Lewis Carroll wrote in 1864 the novel of Alice in Wonderland “Alice`s Adventures under Ground” [1]. The British psychiatrist John Todd (1914-1987) described the curious condition of micro-and macrosomatognosia, altered perceptions of body image, and described it as Alice in Wonderland Syndrome. John Todd described it 1955 and gave it the literary name in his publication","PeriodicalId":73665,"journal":{"name":"Journal of clinical cases & reports","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85082295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}