Journal of clinical & experimental oncology最新文献_第5页

Strong immunogenicity of membrane nanovesicles from dendritic cells 树突状细胞膜纳米囊泡的强免疫原性

Journal of clinical & experimental oncology Pub Date : 2018-01-01 DOI: 10.4172/2324-9110-c3-013

J. Sprent

引用次数: 0

Abzymes as unique biomarkers and targets to monitor and manage chronic disorders and to serve tools for bioengineering of the next-step generation Abzymes作为监测和管理慢性疾病的独特生物标志物和靶点，并为下一代生物工程提供工具

Journal of clinical & experimental oncology Pub Date : 2018-01-01 DOI: 10.4172/2324-9110-C6-023

S. Suchkov

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Synthesis and biological evaluation of new purine-like heterocyclic molecules targeting apoptosis in cancer cell lines 靶向肿瘤细胞凋亡的新型嘌呤样杂环分子的合成及生物学评价

Journal of clinical & experimental oncology Pub Date : 2018-01-01 DOI: 10.4172/2324-9110-c1-009

Kow Koon Kee

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Plasmonic photocatalyst: Hot electron transfer type and hot hole-transfer type 等离子体光催化剂:热电子转移型和热空穴转移型

Journal of clinical & experimental oncology Pub Date : 2018-01-01 DOI: 10.4172/2324-9110-c5-019

S. Naya

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Ki67 in young patients with breast cancer 年轻乳腺癌患者的Ki67

Journal of clinical & experimental oncology Pub Date : 2018-01-01 DOI: 10.4172/2324-9110-C6-024

Y. Rahim

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Inhibition of ribosomal S6 kinase 1 attenuates cell proliferation, migration and invasion of tongue squamous cell carcinoma cells 抑制核糖体S6激酶1可减弱舌鳞癌细胞的增殖、迁移和侵袭

Journal of clinical & experimental oncology Pub Date : 2018-01-01 DOI: 10.4172/2324-9110-C1-008

Ekarat Hitakomate

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Manganese-Enhanced Magnetic Resonance Imaging of Breast Cancer Cells 乳腺癌细胞的锰增强磁共振成像

Journal of clinical & experimental oncology Pub Date : 2018-01-01 DOI: 10.4172/2324-9110-c4-017

Mosa Alhamami

引用次数: 0

Proton accelerated partial breast irradiation (APBI) has an exceptional patient satisfaction profile 质子加速部分乳房照射(APBI)具有特殊的患者满意度概况

Journal of clinical & experimental oncology Pub Date : 2018-01-01 DOI: 10.4172/2324-9110-c6-022

E. Strom

引用次数: 0

Mantle Cell Lymphoma Misdiagnosed as Chronic Lymphocytic Leukemia: Optimization of Diagnostic Approach Mantle细胞淋巴瘤误诊为慢性淋巴细胞白血病：诊断方法的优化

Journal of clinical & experimental oncology Pub Date : 2017-12-05 DOI: 10.4172/2324-9110.1000200

Numan Fateh

{"title":"Mantle Cell Lymphoma Misdiagnosed as Chronic Lymphocytic Leukemia: Optimization of Diagnostic Approach","authors":"Numan Fateh","doi":"10.4172/2324-9110.1000200","DOIUrl":"https://doi.org/10.4172/2324-9110.1000200","url":null,"abstract":"Mantle cell lymphoma (MCL) is a mature B-cell non-Hodgkin lymphoma that is relatively uncommon. MCL is an aggressive lymphoma and at times can share many features with chronic lymphocytic leukemia (CLL). CLL is positive for CD5+ (in 80% of cases), CD20+ (95%) and CD23+ (85%). MCL is also positive for CD5+ (80%) and CD20+ (94%), but generally negative for CD23-. However, there are cases of CD23 positive MCL which can lead to misdiagnosis. Cyclin D1 is more specific than CD markers, but is positive in approximately 85-90% of cases. Thus for 15% of cases this test is also not reliable to diagnose MCL. For example, there are reports of Cyclin D2 and Cyclin D3 involvement instead of the more commonly known Cyclin D1. The same is true for t (11;14) studies by Fluorescence in situ hybridization (FISH) for MCL. Though it is a rare entity, there are known cases of t (11;14) negative MCL. In cases such as these, it may be difficult to correctly diagnose MCL. Therefore, it is important to have an understanding of the similarities and differences of these two diseases and to be aware of the less commonly used tests to help differentiate between MCL and CLL.","PeriodicalId":73658,"journal":{"name":"Journal of clinical & experimental oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47255040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Successful Treatment of a Progressive Primary Cutaneous Diffuse Large B-Cell Lymphoma of the Leg (PCLBCL-LT) with Hyperthermic Isolated Limb Perfusion 高温离体肢体灌注成功治疗进展性原发性腿部皮肤弥漫性大b细胞淋巴瘤(PCLBCL-LT

Journal of clinical & experimental oncology Pub Date : 2017-11-22 DOI: 10.4172/2324-9110.1000207

I. Karampinis, Laura Schwarzwaelder, M. Hoffmann, T. Gaiser, K. Nowak, P. Hohenberger, J. Jakob

{"title":"Successful Treatment of a Progressive Primary Cutaneous Diffuse Large B-Cell Lymphoma of the Leg (PCLBCL-LT) with Hyperthermic Isolated Limb Perfusion","authors":"I. Karampinis, Laura Schwarzwaelder, M. Hoffmann, T. Gaiser, K. Nowak, P. Hohenberger, J. Jakob","doi":"10.4172/2324-9110.1000207","DOIUrl":"https://doi.org/10.4172/2324-9110.1000207","url":null,"abstract":"Purpose: Hyperthermic isolated limb perfusion (ILP) is a highly effective treatment option for locally advanced soft tissue sarcoma and in-transit metastasized malignant melanoma of the extremities. The role of the hyperthermic isolated limb perfusion in the treatment of aggressive cutaneous b-cell lymphoma (PCLBCL-LT) is unknown. \u0000Methods: This is a case presentation of a 65 year old woman with a multifocal recurrence of a cutaneous b-cell lymphoma of leg type successfully treated by hyperthermic isolated limb perfusion with melphalan. Preoperative regimens included systemic chemotherapy and irradiation. \u0000Results: An isolated limb perfusion was performed (100 mg of melphalan, heating 38.5°, cannulation of the superficial femoral artery). One year after the operation a complete response of the disease could be observed. \u0000Conclusion: Regional treatment by hyperthermic isolated limb perfusion with melphalan does lead to local tumor control in relapsed cutaneous lymphoma of the extremities. Therefore, ILP should be considered as a possible alternative treatment in selected cases of chemotherapy resistant PCLBCL-LT.","PeriodicalId":73658,"journal":{"name":"Journal of clinical & experimental oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42419191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0