JMA journal最新文献

{"title":"Representativeness of Social Surveys among Older Individuals Living in Poverty: Who Were Left Behind?","authors":"Daisuke Nishioka, Shiho Kino, Keiko Ueno, Shoko Takemoto, Takuya Kobayashi, Yasunori Higa, Tomoko Ishimura, Masashige Saito, Naoki Kondo","doi":"10.31662/jmaj.2024-0093","DOIUrl":"10.31662/jmaj.2024-0093","url":null,"abstract":"<p><p>As considering only the data of survey respondents overlooks the opinion of voiceless people, acknowledging the direction of response biases of social survey data is crucial. We aimed to examine the representativeness of social surveys among impoverished older individuals. We conducted a cross-sectional study. Using linkage data from the Japan Gerontological Evaluation Study (JAGES) and residential registry data of public assistance (PA), we examined the validity of responses on receiving PA, as documented by the JAGES. Furthermore, we assessed the sociodemographic factors associated with the response to the JAGES using information on age (65-74/75-84/≥85 years), sex (male/female), household composition (living alone or not), nationality (Japanese/others), and level of long-term care needs (not applicable/support required/care needed) using complete data of PA recipients. A multiple modified Poisson regression analysis was performed to calculate the adjusted incidence ratio (IR) for responses to each explanatory variable. Among the sampled 162 older PA recipients, 79 (48.8%) responded to the JAGES. Seven recipients were misclassified as non-recipients in JAGES survey. There was no misclassification among non-recipients. PA recipients living alone were more likely to respond to the JAGES (IR 1.48, 95% confidence interval, 1.02-2.13). Using linkage data of the PA and JAGES databases from different departments within the municipality, we observed that social survey data represented a greater proportion of individuals living alone than those living with others among older impoverished people. To provide equitable policies, stakeholders should collect further information on older impoverished individuals not living alone.</p>","PeriodicalId":73550,"journal":{"name":"JMA journal","volume":"8 3","pages":"947-951"},"PeriodicalIF":1.8,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12328268/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144818495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unfolding the Tapestry of Blood Pressure Variability: Revealing Hidden Dimensions.","authors":"Atsushi Mizuno","doi":"10.31662/jmaj.2025-0209","DOIUrl":"10.31662/jmaj.2025-0209","url":null,"abstract":"","PeriodicalId":73550,"journal":{"name":"JMA journal","volume":"8 3","pages":"882-884"},"PeriodicalIF":1.8,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12328305/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144818503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to: Current Status and Management Strategies of Obstetric Hemorrhage Using Contrast-Enhanced Dynamic Computed Tomography in a Representative Tertiary Perinatal Medical Center in Japan.","authors":"Yoshitsugu Chigusa, Naohiro Suzuki","doi":"10.31662/jmaj.2025-0095","DOIUrl":"https://doi.org/10.31662/jmaj.2025-0095","url":null,"abstract":"","PeriodicalId":73550,"journal":{"name":"JMA journal","volume":"8 3","pages":"1017"},"PeriodicalIF":1.8,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12329108/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144818494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health Insurance and Its Psychosocial Correlates in Patients with Advanced Lung Cancer in Japan.","authors":"Fumimaro Ito, Takashi Sato, Kohei Horiuchi, Daisuke Arai, Keiko Ohgino, Kota Ishioka, Hideki Terai, Shinnosuke Ikemura, Hiroyuki Yasuda, Ichiro Nakachi, Ichiro Kawada, Takashi Inoue, Yoshitaka Oyamada, Takeshi Terashima, Koichi Sayama, Daisuke Fujisawa, Mari Takeuchi, Koichi Fukunaga, Katsuhiko Naoki, Kenzo Soejima","doi":"10.31662/jmaj.2024-0289","DOIUrl":"10.31662/jmaj.2024-0289","url":null,"abstract":"<p><strong>Introduction: </strong>Japan has a national health insurance system that covers at least 70% of regular medical costs and provides additional benefits for high medical costs. In addition, >60% of the population holds private health insurance to reduce financial toxicity. However, there has been a lack of real-world data on private health insurance in the oncology setting in Japan.</p><p><strong>Methods: </strong>A cross-sectional survey of health insurance was conducted at 16 hospitals in Japan between 2013 and 2016. Patients were eligible if they were newly diagnosed with clinical stage IIIB or IV lung cancer. Data collected included patients' health insurance, clinical and sociodemographic characteristics, and self-reported outcomes 3 months after diagnosis.</p><p><strong>Results: </strong>Of the 147 patients, 114 (77.6%) had private health insurance. Patients with private health insurance were significantly younger (p = 0.028), had better performance status (p = 0.029), and reported better quality of life (p = 0.017), specifically in social (p = 0.039) and emotional (p = 0.011) well-being. There were no significant associations between having private health insurance and treatment details, medical satisfaction, or financial issues. Most patients (99.3%) reported that national health insurance is necessary. A substantial proportion of patients (9.8%), particularly those without private health insurance (19.4%), reported that private health insurance is not necessary.</p><p><strong>Conclusions: </strong>Having private health insurance was associated with better quality of life, though there were no significant differences in medical care or financial issues. Our findings suggest that private health insurance plays an auxiliary role in accessing medical care for patients with advanced lung cancer in Japan.</p>","PeriodicalId":73550,"journal":{"name":"JMA journal","volume":"8 3","pages":"743-752"},"PeriodicalIF":1.8,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12329066/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144818470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improvement of Quality of Life by Switching from Oral Semaglutide to Tirzepatide in Patients with Type 2 Diabetes.","authors":"Takahiro Fukaishi, Fumiaki Ishibashi","doi":"10.31662/jmaj.2025-0011","DOIUrl":"10.31662/jmaj.2025-0011","url":null,"abstract":"<p><strong>Introduction: </strong>Tirzepatide, a novel dual glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonist has shown significant promise in weight reduction and glycemic management in patients with type 2 diabetes (T2DM). However, there have been no reports evaluating the quality of life (QOL) in patients who switched from oral semaglutide to tirzepatide. This study prospectively investigated short-term changes in the QOL of these patients.</p><p><strong>Methods: </strong>This study was a single-center, prospective observational study. Participants were patients with T2DM who switched from oral semaglutide to tirzepatide due to insufficient weight reduction between May 1, 2023, and December 31, 2023. The primary outcome was the change in the Diabetes Therapy-Related QOL (DTR-QOL) questionnaire scores from baseline to 3 months after switching. The changes in glycemic management and body weight were also assessed as secondary outcomes.</p><p><strong>Results: </strong>Eleven patients were enrolled in this study. The total DTR-QOL score was significantly improved 3 months after switching (from 58.0 ± 9.9 to 81.5 ± 11.2, p < 0.001). Four subscale domains were also significantly improved (p < 0.001, p < 0.001, p = 0.015 and p < 0.001, respectively). There were no significant changes in glycated hemoglobin levels and body weight 3 months after switching (from 6.8 ± 1.0% to 6.4 ± 0.8%, p = 0.068 and from 86.5 ± 19.6 kg to 84.2 ± 19.7 kg, p = 0.099, respectively).</p><p><strong>Conclusions: </strong>Switching from oral semaglutide to tirzepatide potentially improves overall QOL in patients with T2DM in a short period of time. Further large cohort studies will reinforce the results.</p>","PeriodicalId":73550,"journal":{"name":"JMA journal","volume":"8 3","pages":"809-816"},"PeriodicalIF":1.8,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12328484/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144818474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential Biomarkers in Systemic Lupus Erythematosus.","authors":"Yujie Song, Michihito Kono","doi":"10.31662/jmaj.2025-0190","DOIUrl":"10.31662/jmaj.2025-0190","url":null,"abstract":"<p><p>Systemic lupus erythematosus (SLE) is a complex autoimmune disorder characterized by heterogeneous clinical manifestations and diverse autoantibody production. Despite advances in treatment, many patients experience disease flares throughout their lives, and current biomarkers like anti-double-stranded DNA antibodies and serum complement levels have limitations in accurately reflecting disease activity. This review examines emerging and established biomarkers for SLE diagnosis, disease activity monitoring, and treatment response prediction. We discuss immune cell subsets as potential biomarkers, focusing on plasmacytoid dendritic cells, T cell and B cell subsets, especially focused on T cell subsets. The review highlights how imbalances in these cellular populations correlate with disease activity and specific organ involvement. Furthermore, we discuss cytokines, chemokines, autoantibodies, and complement as biomarkers in SLE. The identification and validation of reliable biomarkers in SLE will ultimately improve clinical decision-making regarding treatment selection, glucocorticoid tapering, and prediction of disease remission, leading to more personalized and effective management strategies.</p>","PeriodicalId":73550,"journal":{"name":"JMA journal","volume":"8 3","pages":"689-698"},"PeriodicalIF":1.8,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12328262/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144818483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Common Marmoset as a Novel Non-human Primate Model for Inner Ear Research.","authors":"Makoto Hosoya","doi":"10.31662/jmaj.2025-0142","DOIUrl":"10.31662/jmaj.2025-0142","url":null,"abstract":"<p><p>Recent advances in molecular biology have led to significant progress in the fields of otology and audiology. Rodents, particularly genetically modified mice, have traditionally served as the primary model for inner ear research. However, growing evidence highlights inter-species differences in hearing research. Simultaneously, the use of human inner ear specimens has become increasingly restricted due to difficulties in specimen collection and ethical concerns. Similarly, the use of human fetuses to study inner ear development is challenging due to ethical issues. Therefore, the embryology of the mammalian inner ear cochlea has been studied using rodent models. These challenges underscore the need for a new research platform that better approximates the human inner ear. The common marmoset (<i>Callithrix jacchus</i>), a New World monkey native to South America, has emerged as a promising alternative. Initially studied in adult models, this primate is now being applied to developmental inner ear research. Its use is expected to yield novel insights. Offering a viewpoint distinct from conventional rodent-based studies. In this study, we outline the advantages of the common marmoset in hearing research and discuss its potential as a primate model animal for future inner ear studies.</p>","PeriodicalId":73550,"journal":{"name":"JMA journal","volume":"8 3","pages":"679-688"},"PeriodicalIF":1.8,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12328889/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144818500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diffuse Polyenthesitis after Intravesical Bacillus Calmette-Guerin Therapy.","authors":"Takashi Nawata, Michihiro Toyoshige, Motoaki Sano","doi":"10.31662/jmaj.2025-0019","DOIUrl":"10.31662/jmaj.2025-0019","url":null,"abstract":"","PeriodicalId":73550,"journal":{"name":"JMA journal","volume":"8 3","pages":"984-985"},"PeriodicalIF":1.8,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12328925/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144818462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypoxemia-induced Wellens-like Electrocardiogram Pattern in Acute Exacerbation of Chronic Obstructive Pulmonary Disease.","authors":"Hirohito Sano, Yuri Yamamoto, Hisatoshi Sugiura","doi":"10.31662/jmaj.2025-0056","DOIUrl":"10.31662/jmaj.2025-0056","url":null,"abstract":"","PeriodicalId":73550,"journal":{"name":"JMA journal","volume":"8 3","pages":"986-987"},"PeriodicalIF":1.8,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12328991/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144818472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Necrotizing Pneumonia Caused by Community-acquired Methicillin-resistant <i>Staphylococcus aureus</i> Following Influenza.","authors":"Maiko Awashima, Yoshiko Kichikawa, Ko Suzuki, Hideyuki Horikoshi","doi":"10.31662/jmaj.2025-0093","DOIUrl":"10.31662/jmaj.2025-0093","url":null,"abstract":"","PeriodicalId":73550,"journal":{"name":"JMA journal","volume":"8 3","pages":"988-989"},"PeriodicalIF":1.8,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12328273/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144818479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}