JMA journal最新文献_第3页

A Case of the Monocle Sign in Facial Nerve Palsy Caused by External Auditory Canal Cancer on 18F-fluorodeoxyglucose-positron Emission Tomography/Computed Tomography. 外耳道癌致面神经麻痹单片征18f -氟脱氧葡萄糖-正电子发射断层扫描/计算机断层扫描1例

IF 1.5

JMA journal Pub Date : 2025-04-28 Epub Date: 2025-03-14 DOI: 10.31662/jmaj.2024-0303

Reiko Yagi, Ken Yamagiwa, Tomoyuki Fujioka, Junichi Tsuchiya, Tomoaki Asamori, Takeshi Tsutsumi, Ukihide Tateishi

引用次数: 0

Spontaneous Intramuscular Hemorrhage in Anti-melanoma Differentiation-associated Gene 5 Antibody-positive Dermatomyositis. 抗黑色素瘤分化相关基因5抗体阳性皮肌炎患者自发性肌肉内出血

IF 1.5

JMA journal Pub Date : 2025-04-28 Epub Date: 2025-02-28 DOI: 10.31662/jmaj.2024-0412

Tomoyuki Mutoh, Hidetoshi Mitsui, Hiroshi Fujii

{"title":"Spontaneous Intramuscular Hemorrhage in Anti-melanoma Differentiation-associated Gene 5 Antibody-positive Dermatomyositis.","authors":"Tomoyuki Mutoh, Hidetoshi Mitsui, Hiroshi Fujii","doi":"10.31662/jmaj.2024-0412","DOIUrl":"10.31662/jmaj.2024-0412","url":null,"abstract":"Anti-melanoma differentiation-associated gene 5 (MDA5) antibody-positive dermatomyositis (DM) is characterized by mild or absent muscle involvement and unique skin lesions such as cutaneous ulceration and palmar papules, commonly associated with rapidly progressive interstitial lung disease (RP-ILD), causing fatal outcomes. Spontaneous intramuscular hemorrhage (SIH) is an extremely rare but severe complication that remains under-recognized in DM. Here, we report a case of multiple SIH in a 72-year-old Japanese woman with anti-MDA5 antibody-positive DM and RP-ILD. The patient initially presented with fever, fatigue, and abnormal liver function, leading to a provisional diagnosis of autoimmune hepatitis. Following a 3-week moderate-dose prednisolone treatment, bilateral thigh hematomas suddenly developed without trauma or anticoagulant therapy. Laboratory findings revealed elevated creatine kinase and ferritin levels, reduced factor XIII (F13) activity, and anemia. Computed tomography (CT) imaging showed hematomas in multiple muscles and ILD. Although high-dose prednisolone administration gradually ameliorated the intramuscular hemorrhage, skin manifestations indicative of DM and dyspnea on exertion emerged after tapering prednisolone. Exacerbation of ILD was observed on CT imaging. Comprehensive analysis detected anti-MDA5 and anti-Ro52 antibodies without anti-F13 autoantibody, eventually leading to the diagnosis of anti-MDA5 antibody-positive DM with SIH and RP-ILD. Despite aggressive immunosuppressants, she died of RP-ILD-related respiratory failure. This case highlights the importance of considering DM as a differential diagnosis and investigating cutaneous manifestations indicative of DM in cases where the SIH etiology is unclear. Evaluation of myositis-specific and myositis-associated autoantibodies is crucial to ensure adequate diagnosis when SIH associated with DM is highly suspected.","PeriodicalId":73550,"journal":{"name":"JMA journal","volume":"8 2","pages":"641-645"},"PeriodicalIF":1.5,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12095137/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Raccoon Eye Caused by Dialysis-related Amyloidosis. 透析相关淀粉样变引起的浣熊眼。

IF 1.5

JMA journal Pub Date : 2025-04-28 Epub Date: 2025-03-28 DOI: 10.31662/jmaj.2024-0376

Yuri Furuhashi, Tomotaka Takanosu, Masahiro Miki, Hiroko Kikuchi

引用次数: 0

Cerebral Fat Embolism Syndrome. 脑脂肪栓塞综合征。

IF 1.5

JMA journal Pub Date : 2025-04-28 Epub Date: 2025-01-31 DOI: 10.31662/jmaj.2024-0345

Daichi Motomura, Tomotaka Takanosu

引用次数: 0

Contribution to Establishing a Foundation for Promoting Cancer Control in Japan by Providing Precise Cancer Information and Establishing a Research Infrastructure-Secondary Publication. 通过提供精确的癌症信息和建立研究基础设施，为促进日本癌症控制建立基金会的贡献-二次出版。

IF 1.5

JMA journal Pub Date : 2025-04-28 Epub Date: 2025-04-04 DOI: 10.31662/jmaj.2024-0379

Tomotaka Sobue

{"title":"Contribution to Establishing a Foundation for Promoting Cancer Control in Japan by Providing Precise Cancer Information and Establishing a Research Infrastructure-Secondary Publication.","authors":"Tomotaka Sobue","doi":"10.31662/jmaj.2024-0379","DOIUrl":"10.31662/jmaj.2024-0379","url":null,"abstract":"At the beginning of 2000, the National Cancer Center had little involvement in cancer statistics. In addition, cancer incidence data were collected by regional cancer registries (approximately 30 prefectures have on-site registries), but the problems were that (1) the completeness of the registration was low, (2) the registration method was not standardized, and (3) usage was limited. In the Third Comprehensive Strategic Cancer Research Project (2004-2013), Field 7, \"Research on Developing Cancer Surveillance System and Disseminating Cancer Information,\" was added, and we could build a system to aggregate the latest cancer statistical data from Japan and provide it as content for cancer information services. In addition, within the Regional Cancer Registry Research Group, we promoted the standardization of population-based cancer registry methods through \"formulation and dissemination of standard registration forms\" and \"development and dissemination of standard registry systems.\" We believe that these factors served as the basis for the smooth transfer to the National Cancer Registry under the Cancer Registry Promotion Act, which was enacted in 2013. In contrast, to take over the function of Hisamichi's \"Evaluation of the Effectiveness of New Cancer Screening Methods\" report published in 2001, the Ministry of Health, Labour and Welfare Cancer Research Grant \"Research on the Establishment of Appropriate Methods for Cancer Screening and Evaluation Methods\" group, which started in 2003, formulated the guideline development procedure and updated the guidelines, and the work of updating the guidelines was subsequently taken over by the National Cancer Center. This remains an important mechanism to ensure that cancer screening methods that do not have a scientifically confirmed balance between benefits and harms are not introduced into policy.","PeriodicalId":73550,"journal":{"name":"JMA journal","volume":"8 2","pages":"317-322"},"PeriodicalIF":1.5,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12095563/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Difference in Age- and Sex-adjusted Prevalence of Diseases between Employees and Nonemployees with Health Insurance in Japan. 日本有健康保险的雇员和非雇员之间经年龄和性别调整的疾病患病率的差异

IF 1.5

JMA journal Pub Date : 2025-04-28 Epub Date: 2025-02-14 DOI: 10.31662/jmaj.2024-0281

Masakazu Kohda, Akira Okada, Hideo Yasunaga

{"title":"Difference in Age- and Sex-adjusted Prevalence of Diseases between Employees and Nonemployees with Health Insurance in Japan.","authors":"Masakazu Kohda, Akira Okada, Hideo Yasunaga","doi":"10.31662/jmaj.2024-0281","DOIUrl":"10.31662/jmaj.2024-0281","url":null,"abstract":"Introduction: Administrative claims data are used in clinical studies. However, individuals insured by different insurance systems have different backgrounds, ages, and disease prevalences. This study aimed to examine the crude and adjusted prevalence of diseases between employee and nonemployee health insurance in Japan.Methods: We conducted a cross-sectional study using the DeSC database, an administrative claims database covering multiple insurers. We calculated the prevalence of 10 disease categories and 6 specific cancers with and without adjustments for age and sex and compared them between the employee (Kempo) and nonemployee (Kokuho) insurance systems.Results: We identified 740,217 and 3,312,042 individuals covered by Kempo and Kokuho, respectively. The Kokuho group showed a higher crude prevalence of malignancies, endocrinological diseases, mental disorders, neurological diseases, cardiovascular diseases, and kidney or genitourinary diseases. The adjusted prevalence differed in mental disorders (7.2% vs. 10.6%), neurological diseases (10.5% vs. 14.0%), and gastrointestinal diseases (50.1% vs. 34.1%) between the Kempo and Kokuho groups.Conclusions: While using administrative claims data, researchers should consider differences in patient backgrounds and disease prevalence among insurance providers.","PeriodicalId":73550,"journal":{"name":"JMA journal","volume":"8 2","pages":"411-416"},"PeriodicalIF":1.5,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12095125/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Case of Hepatocellular Carcinoma Associated with Hepatic Sarcoidosis. 肝细胞癌合并肝结节病1例。

IF 1.5

JMA journal Pub Date : 2025-04-28 Epub Date: 2025-01-31 DOI: 10.31662/jmaj.2024-0387

Yasuo Nagai, Kosei Takagi, Kazuya Yasui, Kazuya Kariyama, Tomokazu Fuji, Toshiyoshi Fujiwara

引用次数: 0

Dissemination of Information to Foreigners in Preparation for Natural Disasters: Response to a Letter to the Editor. 向外国人传播防备自然灾害的信息：一封给编辑的信的回应。

IF 1.5

JMA journal Pub Date : 2025-04-28 Epub Date: 2025-01-31 DOI: 10.31662/jmaj.2024-0360

Akiko Morimoto, Nao Sonoda

引用次数: 0

Bilateral Mandibular Condylar Fractures. 双侧下颌髁骨折。

IF 1.5

JMA journal Pub Date : 2025-04-28 Epub Date: 2025-03-07 DOI: 10.31662/jmaj.2024-0378

Koji Tajima

引用次数: 0

Clinical Information and Prognosis of High-risk Luminal Breast Cancer Subjects Eligible for the MonarhE Study. 符合MonarhE研究的高危腔内乳腺癌受试者的临床信息和预后。

IF 1.5

JMA journal Pub Date : 2025-04-28 Epub Date: 2025-02-14 DOI: 10.31662/jmaj.2024-0243

Mio Adachi, Toshiyuki Ishiba, Sakiko Maruya, Kumiko Hayashi, Yuichi Kumaki, Goshi Oda, Tomoyuki Aruga

{"title":"Clinical Information and Prognosis of High-risk Luminal Breast Cancer Subjects Eligible for the MonarhE Study.","authors":"Mio Adachi, Toshiyuki Ishiba, Sakiko Maruya, Kumiko Hayashi, Yuichi Kumaki, Goshi Oda, Tomoyuki Aruga","doi":"10.31662/jmaj.2024-0243","DOIUrl":"10.31662/jmaj.2024-0243","url":null,"abstract":"Introduction: Luminal breast cancer is the most common breast cancer subtype. Although its prognosis can be good, this type of breast cancer is characterized by a high incidence of late recurrence. However, to the best of our knowledge, there are no publications showing prognostic value regarding the invasive-disease-free survival (IDFS) and distant relapse-free survival in this group in clinical practice. Therefore, this study examined the clinical data and prognosis of patients participating in the MonarchE trial.Methods: This study included patients who underwent surgery at Tokyo Metropolitan Komagome Hospital and whose corresponding prognosis to the Monarch E trial could be followed up.Results: The total number of participants was 152, of whom 104 (68%) were treated with chemotherapy. Seventy-five patients (49%) were postmenopausal. The IDFS after 5 years was 85.0%. Although IDFS did not differ in terms of the menstrual status, premenopausal patients tended to receive a higher proportion of tamoxifen, and there was a greater number of patients treated with chemotherapy. However, neither chemotherapy nor menstrual statuses were found to affect the IDFS incidence.Conclusions: Real clinical data applicable to the MonarchE study were examined. Our univariate analysis revealed that there were no factors affecting IDFS.","PeriodicalId":73550,"journal":{"name":"JMA journal","volume":"8 2","pages":"486-497"},"PeriodicalIF":1.5,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12095113/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0