ISRN obstetrics and gynecology最新文献_第4页

Tubercular Ascites Simulating Ovarian Hyperstimulation Syndrome following In Vitro Fertilization and Embryo Transfer Pregnancy. 体外受精和胚胎移植妊娠后结核性腹水模拟卵巢过度刺激综合征。

ISRN obstetrics and gynecology Pub Date : 2013-09-18 eCollection Date: 2013-01-01 DOI: 10.1155/2013/176487

Amar Ramachandran, Pratap Kumar, Naveen Manohar, Raviraj Acharya, Anita Eipe, Rajeshwari G Bhat, Lorraine Simone Dias, Padmaja Raghavan

引用次数: 2

Serum levels of asymmetric dimethylarginine, vascular endothelial growth factor, and nitric oxide metabolite levels in preeclampsia patients. 子痫前期患者血清不对称二甲基精氨酸、血管内皮生长因子和一氧化氮代谢物水平的研究

ISRN obstetrics and gynecology Pub Date : 2013-09-11 eCollection Date: 2013-01-01 DOI: 10.1155/2013/104213

Marjan Noorbakhsh, Maryam Kianpour, Mehdi Nematbakhsh

{"title":"Serum levels of asymmetric dimethylarginine, vascular endothelial growth factor, and nitric oxide metabolite levels in preeclampsia patients.","authors":"Marjan Noorbakhsh, Maryam Kianpour, Mehdi Nematbakhsh","doi":"10.1155/2013/104213","DOIUrl":"https://doi.org/10.1155/2013/104213","url":null,"abstract":"Background. Hypertensive disorder generally complicates 5-10 percent of all pregnancies. Angiogenic growth factors may be helpful for the diagnosis and prediction of preeclampsia. Therefore, in this study we attempted to determine the serum levels of asymmetric dimethylarginine (ADMA), vascular endothelial growth factor (VEGF), and nitric oxide (NO) metabolite (nitrite) in preeclampsia patients and compared the levels with those obtained from normal pregnant women. Methods. Ninety pregnant women (19-33 years old) in two groups of preeclampsia and normal were considered during 2012. The levels of ADMA, VEGF, and nitrite were measured in maternal serum samples using ELISA kits. Results. Significant increase of VEGF and nitrite levels was observed in preeclampsia patients when compared with other groups (P < 0.05). The serum level of ADMA demonstrated a similar increased trend in preeclampsia patients; however, the increase was not statistically significant (P = 0.08). Conclusion. The findings reveal that the elevation of serum levels of VEGF and nitrite and possibly ADMA may be involved in the pathogenesis of preeclampsia. ","PeriodicalId":73520,"journal":{"name":"ISRN obstetrics and gynecology","volume":"2013 ","pages":"104213"},"PeriodicalIF":0.0,"publicationDate":"2013-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/104213","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31793586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 20

Effectiveness of a novel device in the reduction of cesarean deliveries. 一种新型设备在减少剖腹产方面的效果。

ISRN obstetrics and gynecology Pub Date : 2013-09-01 eCollection Date: 2013-01-01 DOI: 10.1155/2013/173278

Daniel A Burns

{"title":"Effectiveness of a novel device in the reduction of cesarean deliveries.","authors":"Daniel A Burns","doi":"10.1155/2013/173278","DOIUrl":"10.1155/2013/173278","url":null,"abstract":"Objective. To test the hypothesis that the use of the HEM-AVERT Perianal Stabilizer will result in a reduction of cesarean births and shorter duration of second-stage labor. Study Design. In a prospective controlled trial, 102 women scheduled for vaginal delivery were randomized to either the HEM-AVERT investigational device or control group. Ninety eight (98) patients completed the study. A chi-square test was used to evaluate the difference in the number of cesarean deliveries between the investigational and control groups. Duration of second-stage labor was assessed as a secondary outcome. Results. Six (6) of the 50 patients in the investigational group (12%) failed to deliver vaginally and required cesarean delivery. Comparatively, 19 of the 48 control patients (39.6%) required cesarean delivery. Duration of second-stage labor was shorter in the investigational group, but the difference was not statistically significant. Results from 4 patients were excluded due to protocol violations. Conclusion. The HEM-AVERT device effectively reduced the incidence rate of cesarean deliveries in the investigational group when compared to women who delivered without use of the device. This trial is registered with ClinicalTrials.gov NCT01739543. ","PeriodicalId":73520,"journal":{"name":"ISRN obstetrics and gynecology","volume":"2013 ","pages":"173278"},"PeriodicalIF":0.0,"publicationDate":"2013-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773949/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31769064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Posterior Intravaginal Slingplasty versus Unilateral Sacrospinous Ligament Fixation in Treatment of Vaginal Vault Prolapse. 后阴道内吊带成形术与单侧骶棘韧带固定治疗阴道穹窿脱垂。

ISRN obstetrics and gynecology Pub Date : 2013-08-13 eCollection Date: 2013-01-01 DOI: 10.1155/2013/958670

Virva Nyyssönen, Anne Talvensaari-Mattila, Markku Santala

{"title":"Posterior Intravaginal Slingplasty versus Unilateral Sacrospinous Ligament Fixation in Treatment of Vaginal Vault Prolapse.","authors":"Virva Nyyssönen, Anne Talvensaari-Mattila, Markku Santala","doi":"10.1155/2013/958670","DOIUrl":"https://doi.org/10.1155/2013/958670","url":null,"abstract":"Objective. To investigate the differences in efficacy, postoperative complications, and patient satisfaction between posterior intravaginal slingplasty (PIVS) and unilateral sacrospinous ligament fixation (SSLF) procedures. Study Design. A retrospective study of thirty-three women who underwent PIVS or SSLF treatment for vaginal vault prolapse in Oulu University Hospital. The patients were invited to a follow-up visit to evaluate the objective and subjective outcomes. Median follow-up time was 16 months (range 6-52). The anatomical outcome was detected by the Pelvic Organ Prolapse Quantification (POP-Q) system. Information on urinary, bowel, and sexual dysfunctions and overall satisfaction was gathered with specific questionnaire. The data were analyzed using Mann-Whitney U test and Fisher's exact test. Results. Mesh erosion was found in 4 (25%) patients in the PIVS group. Anatomical stage II prolapse or worse (any POP-Q point ≥-1) was detected in 8 (50%) patients in the PIVS group and 9 (53%) patients in the SSLF group. Overall satisfaction rates were 62% and 76%, respectively. Conclusion. The efficacy of PIVS and SSLF is equally poor, and the rate of vaginal erosion is intolerably high with the PIVS method. Based on our study, we cannot recommend the usage of either technique in operative treatment of vaginal vault prolapse. ","PeriodicalId":73520,"journal":{"name":"ISRN obstetrics and gynecology","volume":"2013 ","pages":"958670"},"PeriodicalIF":0.0,"publicationDate":"2013-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/958670","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31700943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Maternal and Perinatal Outcomes of Exercise in Pregnant Women with Chronic Hypertension and/or Previous Preeclampsia: A Randomized Controlled Trial. 慢性高血压和/或先兆子痫孕妇运动对母体和围产期的影响：随机对照试验。

ISRN obstetrics and gynecology Pub Date : 2013-08-12 eCollection Date: 2013-01-01 DOI: 10.1155/2013/857047

Karina Tamy Kasawara, Camila Schneider Gannuny Burgos, Simony Lira do Nascimento, Néville Oliveira Ferreira, Fernanda Garanhani Surita, João Luiz Pinto E Silva

{"title":"Maternal and Perinatal Outcomes of Exercise in Pregnant Women with Chronic Hypertension and/or Previous Preeclampsia: A Randomized Controlled Trial.","authors":"Karina Tamy Kasawara, Camila Schneider Gannuny Burgos, Simony Lira do Nascimento, Néville Oliveira Ferreira, Fernanda Garanhani Surita, João Luiz Pinto E Silva","doi":"10.1155/2013/857047","DOIUrl":"10.1155/2013/857047","url":null,"abstract":"Objectives. To evaluate the association between physical exercise supervised in pregnant women with chronic hypertension and/or previous preeclampsia and maternal and neonatal outcomes. Method. Randomized controlled trial, which included 116 pregnant women with chronic hypertension and/or previous preeclampsia, considered risk of preeclampsia development. They were divided into two groups: study group that performed physical exercise with a stationary bicycle once a week, for 30 minutes; the intensity was controlled (heart rate 20% above resting values), under professional supervision and a control group that was not engaged in any physical exercise. The data was retrieved from medical charts. Significance level assumed was 5%. Results. Women from study group performed 9.24 ± 7.03 of physical exercise sessions. There were no differences between groups comparing type of delivery and maternal outcomes, including maternal morbidity and hospitalization in intensive unit care, and neonatal outcomes, including birth weight, adequacy of weight to gestational age, prematurity, Apgar scale at first and fifth minutes, hospitalization in intensive unit care, and neonatal morbidity. Conclusions. Physical exercise using a stationary bicycle in pregnant women with chronic hypertension and/or previous preeclampsia, once a week, under professional supervision, did not interfere in the delivery method and did not produce maternal and neonatal risks of the occurrence of morbidity. This trial is registered with ClinicalTrials.gov NCT01395342. ","PeriodicalId":73520,"journal":{"name":"ISRN obstetrics and gynecology","volume":"2013 ","pages":"857047"},"PeriodicalIF":0.0,"publicationDate":"2013-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753734/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31700942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Minimally invasive surgery in gynecologic oncology. 妇科肿瘤微创手术。

ISRN obstetrics and gynecology Pub Date : 2013-08-12 eCollection Date: 2013-01-01 DOI: 10.1155/2013/312982

Kristina M Mori, Nikki L Neubauer

{"title":"Minimally invasive surgery in gynecologic oncology.","authors":"Kristina M Mori, Nikki L Neubauer","doi":"10.1155/2013/312982","DOIUrl":"https://doi.org/10.1155/2013/312982","url":null,"abstract":"Minimally invasive surgery has been utilized in the field of obstetrics and gynecology as far back as the 1940s when culdoscopy was first introduced as a visualization tool. Gynecologists then began to employ minimally invasive surgery for adhesiolysis and obtaining biopsies but then expanded its use to include procedures such as tubal sterilization (Clyman (1963), L. E. Smale and M. L. Smale (1973), Thompson and Wheeless (1971), Peterson and Behrman (1971)). With advances in instrumentation, the first laparoscopic hysterectomy was successfully performed in 1989 by Reich et al. At the same time, minimally invasive surgery in gynecologic oncology was being developed alongside its benign counterpart. In the 1975s, Rosenoff et al. reported using peritoneoscopy for pretreatment evaluation in ovarian cancer, and Spinelli et al. reported on using laparoscopy for the staging of ovarian cancer. In 1993, Nichols used operative laparoscopy to perform pelvic lymphadenectomy in cervical cancer patients. The initial goals of minimally invasive surgery, not dissimilar to those of modern medicine, were to decrease the morbidity and mortality associated with surgery and therefore improve patient outcomes and patient satisfaction. This review will summarize the history and use of minimally invasive surgery in gynecologic oncology and also highlight new minimally invasive surgical approaches currently in development. ","PeriodicalId":73520,"journal":{"name":"ISRN obstetrics and gynecology","volume":"2013 ","pages":"312982"},"PeriodicalIF":0.0,"publicationDate":"2013-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/312982","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31700941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 30

Development and adaptation of Iranian youth reproductive health questionnaire. 制定和修改伊朗青年生殖健康调查表。

ISRN obstetrics and gynecology Pub Date : 2013-07-31 eCollection Date: 2013-01-01 DOI: 10.1155/2013/950278

Abbas Mousavi, Afsaneh Keramat, Katayon Vakilian, Safar Ali Esmaeili Vardanjani

{"title":"Development and adaptation of Iranian youth reproductive health questionnaire.","authors":"Abbas Mousavi, Afsaneh Keramat, Katayon Vakilian, Safar Ali Esmaeili Vardanjani","doi":"10.1155/2013/950278","DOIUrl":"https://doi.org/10.1155/2013/950278","url":null,"abstract":"Iran is a young country, and sexual behavior is shaped in this period. This research aimed to provide an assessment tool to evaluate Iranian youth reproductive health. This multistage research was conducted to design a valid questionnaire in the domains of knowledge, attitude, and behavior of the youth in order to evaluate behavior change programs. For this reason, after conducting a careful literature review and a qualitative research, the questionnaire was prepared. Forward and backward translations were performed. Professionals and students were used to make sure of qualitative and quantitative content and face validity. After conducting the pilot study on 100 students and eliminating defects in performance, reliability was evaluated by test-retest and Cronbach's alpha was calculated. In this study, out of 268 questions, 198 were retained after face and content validity. Self-efficacy of communication with father and mother, self-efficacy of condom use, and self-efficacy of abstinence had the highest Cronbach's alpha. Moreover, communication with parents regarding reproductive health issues and attitude to abstinence had a high Cronbach's alpha, as well. It seems to be a good instrument for assessment of Iranian reproductive health, and we are going to assess youth reproductive health in the future. ","PeriodicalId":73520,"journal":{"name":"ISRN obstetrics and gynecology","volume":"2013 ","pages":"950278"},"PeriodicalIF":0.0,"publicationDate":"2013-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/950278","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31689534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

Investigating the Relationship between Serum Level of s-Met (Soluble Hepatic Growth Factor Receptor) and Preeclampsia in the First and Second Trimesters of Pregnancy. 研究妊娠头三个月和后三个月血清中 s-Met（可溶性肝生长因子受体）水平与子痫前期的关系

ISRN obstetrics and gynecology Pub Date : 2013-07-31 eCollection Date: 2013-01-01 DOI: 10.1155/2013/925062

Farshad Naghshvar, Zhila Torabizadeh, Narges Moslemi Zadeh, Hooman Mirbaha, Parand Gheshlaghi

{"title":"Investigating the Relationship between Serum Level of s-Met (Soluble Hepatic Growth Factor Receptor) and Preeclampsia in the First and Second Trimesters of Pregnancy.","authors":"Farshad Naghshvar, Zhila Torabizadeh, Narges Moslemi Zadeh, Hooman Mirbaha, Parand Gheshlaghi","doi":"10.1155/2013/925062","DOIUrl":"10.1155/2013/925062","url":null,"abstract":"Introduction. Preeclampsia (PE) is an important cause of mortality and morbidity for mothers, fetuses, and the newborns. Placenta plays a pivotal role in pathogenesis of PE. Hepatic growth factor (HGF) is a cytokine expressed by the mesenchymal stalk of placental villi during pregnancy and assumes a paracrine role in trophoblasts which express its receptor (c-MET). In the present study, we investigate the diagnostic value of s-Met (the soluble form of the receptor) in the first and second trimesters of pregnancy for early diagnosis of preeclampsia. Method and Materials. This is a case-control study conducted on 95 pregnant women. The serum level of s-Met was measured in the first and second trimesters, and the participants were followed until delivery. 44 individuals with preeclampsia (the case group) and 51 individuals without preeclampsia (the control group) were evaluated. Results. Serum level of s-Met in preeclamptic participants was lower than that of the control group in both the first and the second trimesters (P < 0.0001). In addition, serum levels of s-Met were significantly lower during the first and second trimesters in patients with early, severe preeclampsia compared to those with late, mild preeclampsia (P < 0.0001). The sensitivity and specificity of s-Met in the first and second trimesters were, respectively, (83%, 94%) and (77%, 94%) for early preeclampsia and (88%, 92%) and (86%, 98%) for severe preeclampsia. Conclusion. Considering our findings, serum level of s-Met may be used as a predictive factor for early detection of preeclampsia. Further research is required to corroborate the functional and therapeutic value of s-Met in preeclampsia. ","PeriodicalId":73520,"journal":{"name":"ISRN obstetrics and gynecology","volume":"2013 ","pages":"925062"},"PeriodicalIF":0.0,"publicationDate":"2013-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747406/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31689606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Expression of the h19 oncofetal gene in premalignant lesions of cervical cancer: a potential targeting approach for development of nonsurgical treatment of high-risk lesions. h19癌胎基因在宫颈癌癌前病变中的表达:发展非手术治疗高危病变的潜在靶向方法

ISRN obstetrics and gynecology Pub Date : 2013-07-31 eCollection Date: 2013-01-01 DOI: 10.1155/2013/137509

Tomer Feigenberg, Ofer N Gofrit, Galina Pizov, Avraham Hochberg, Abraham Benshushan

{"title":"Expression of the h19 oncofetal gene in premalignant lesions of cervical cancer: a potential targeting approach for development of nonsurgical treatment of high-risk lesions.","authors":"Tomer Feigenberg, Ofer N Gofrit, Galina Pizov, Avraham Hochberg, Abraham Benshushan","doi":"10.1155/2013/137509","DOIUrl":"https://doi.org/10.1155/2013/137509","url":null,"abstract":"Background. Recent data suggest a role for H19 gene in promoting cancer transformation and progression. Cervical cancer, progresses from high-grade lesions (CIN3). At present, it is unclear if CIN lesions express H19. Objectives. To determine H19 expression in patient samples of CIN3 as well as the ability of a construct in which the promoter from the H19 gene drives expression of the diphtheria toxin A chain (DTA) to inhibit cervical cancer cell growth in vitro. Methods. H19 transcript levels were evaluated on 10 biopsies of CIN3 using in situ hybridization. PCR was used to examine H19 expression in cervical cancer cell lines and in two samples from a patient with cervical carcinoma. Cell lines were transfected with H19-DTA to determine its impact on cell number. Results. H19 gene was expressed in the area of CIN3 in 9 out of 10 samples. RT-PCR indicated expression of H19 in cervical cancer samples and in one of the three cell lines examined. Transfection of all cell lines with H19-DTA vector resulted in inhibited cell growth. Conclusions. H19 is expressed in the majority of CIN3 samples. These results suggest that most CIN3 lesions could be targeted by H19-DTA. Further in vivo preclinical studies are thus warranted. ","PeriodicalId":73520,"journal":{"name":"ISRN obstetrics and gynecology","volume":"2013 ","pages":"137509"},"PeriodicalIF":0.0,"publicationDate":"2013-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/137509","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31689604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 14

Treatment of Uterine Myoma with 2.5 or 5 mg Mifepristone Daily during 3 Months with 9 Months Posttreatment Followup: Randomized Clinical Trial. 每日2.5或5mg米非司酮治疗子宫肌瘤3个月及治疗后9个月随访:随机临床试验。

ISRN obstetrics and gynecology Pub Date : 2013-07-29 eCollection Date: 2013-01-01 DOI: 10.1155/2013/649030

Josep Lluis Carbonell, Rita Acosta, Yasmirian Pérez, Roberto Garcés, Carlos Sánchez, Giuseppe Tomasi

{"title":"Treatment of Uterine Myoma with 2.5 or 5 mg Mifepristone Daily during 3 Months with 9 Months Posttreatment Followup: Randomized Clinical Trial.","authors":"Josep Lluis Carbonell, Rita Acosta, Yasmirian Pérez, Roberto Garcés, Carlos Sánchez, Giuseppe Tomasi","doi":"10.1155/2013/649030","DOIUrl":"https://doi.org/10.1155/2013/649030","url":null,"abstract":"Objectives. To evaluate the efficacy, safety, and quality of life by using 2.5 and mifepristone 5 mg daily doses to treat uterine fibroids over 3 months with a 9-month followup period. Design. Randomized clinical trial. Place. \"Eusebio Hernández\" Hospital, Havana, Cuba. Subjects. 220 women with symptomatic uterine fibroids. Treatment. One-half (2.5 mg) or one-whole 5 mg mifepristone tablet. Variables to Evaluate Efficacy. Changes in fibroid and uterine volumes, in symptomatic prevalence and intensity, and in quality of life. Results. After 3-month treatment, fibroid volume decreased by 27.9% (CI 95% 20-35) and 45.5% (CI 95% 37-62), in the 2.5 and 5 mg groups, respectively, P = 0.003. There was no difference in the prevalence of symptoms at the end of treatment, unlike after 6- and 9-month followup when there was a difference. Amenorrhea was significantly higher in the 5 mg group, P = 0.001. There were no significant differences in mifepristone side effects between the groups. Both groups displayed a similar improvement in quality of life. Conclusions. The 2.5 mg dosage resulted in a lesser reduction in fibroid size but a similar improvement in quality of life when compared to the 5 mg dose. This trial is registered with ClinicalTrials.gov NCT01786226. ","PeriodicalId":73520,"journal":{"name":"ISRN obstetrics and gynecology","volume":"2013 ","pages":"649030"},"PeriodicalIF":0.0,"publicationDate":"2013-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/649030","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31689605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 20