Intelligent medicine最新文献

{"title":"A model simulation on the SARS-CoV-2 Omicron variant containment in Beijing, China","authors":"Shihao Liang ,&nbsp;Tianhong Jiang ,&nbsp;Zengtao Jiao ,&nbsp;Zhengyuan Zhou","doi":"10.1016/j.imed.2022.10.005","DOIUrl":"10.1016/j.imed.2022.10.005","url":null,"abstract":"<div><h3>Objective</h3><p>The Omicron variant of SARS-COV-2 is replacing previously circulating variants around the world in 2022. Sporadic outbreaks of the Omicron variant into China have posed a concern how to properly response to battle against evolving coronavirus disease 2019 (COVID-19).</p></div><div><h3>Methods</h3><p>Based on the epidemic data from website announced by Beijing Center for Disease Control and Prevention for the recent outbreak in Beijing from April 22nd to June 8th in 2022, we developed a modified SEPIR model to mathematically simulate the customized dynamic COVID-zero strategy and project transmissions of the Omicron epidemic. To demonstrate the effectiveness of dynamic-changing policies deployment during this outbreak control, we modified the transmission rate into four parts according to policy-changing dates as April 22nd to May 2nd, May 3rd to 11st, May 12th to 21st, May 22nd to June 8th, and we adopted Markov chain Monte Carlo (MCMC) to estimate different transmission rate. Then we altered the timing and scaling of these measures used to understand the effectiveness of these policies on the Omicron variant.</p></div><div><h3>Results</h3><p>The estimated effective reproduction number of four parts were 1.75 (95% CI 1.66–1.85), 0.89 (95% CI 0.79–0.99), 1.15 (95% CI 1.05–1.26) and 0.53 (95% CI 0.48 -0.60), respectively.  In the experiment, we found that till June 8th the cumulative cases would rise to 132,609 (95% CI 59,667–250,639), 73.39 times of observed cumulative cases number 1,807 if no policy were implemented on May 3rd, and would be 3,235 (95% CI 1,909 - 4,954), increased by 79.03% if no policy were implemented on May 22nd. A 3-day delay of the implementation of policies would led to increase of cumulative cases by 58.28% and a 7-day delay would led to increase of cumulative cases by 187.00%. On the other hand, taking control measures 3 or 7 days in advance would result in merely 38.63% or 68.62% reduction of real cumulative cases. And if lockdown implemented 3 days before May 3rd, the cumulative cases would be 289 (95% CI 211–378), reduced by 84%, and the cumulative cases would be 853 (95% CI 578–1,183), reduced by 52.79% if lockdown implemented 3 days after May 3rd.</p></div><div><h3>Conclusion</h3><p>The dynamic COVID-zero strategy might be able to effectively minimize the scale of the transmission, shorten the epidemic period and reduce the total number of infections.</p></div>","PeriodicalId":73400,"journal":{"name":"Intelligent medicine","volume":"3 1","pages":"Pages 10-15"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677562/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9079920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Machine learning approach for label-free rapid detection and identification of virus using Raman spectra","authors":"Rajath Alexander ,&nbsp;Sheetal Uppal ,&nbsp;Anusree Dey ,&nbsp;Amit Kaushal ,&nbsp;Jyoti Prakash ,&nbsp;Kinshuk Dasgupta","doi":"10.1016/j.imed.2022.10.001","DOIUrl":"10.1016/j.imed.2022.10.001","url":null,"abstract":"<div><h3><strong>Objective</strong></h3><p>The objective of this study was to develop a robust method for rapid detection and identification of the virus based on Raman spectroscopy combined with machine learning approach.</p></div><div><h3><strong>Methods</strong></h3><p>We have used saliva spiked with different bacterial viruses such as P1 Phage, M13 Phage, and Lambda Phage, for demonstrating the utility of this method for virus detection. The Raman spectra collected from a large number of independent samples, each of different phages with and without saliva were used to train a supervised convolutional neural network (CNN) with its hyperparameters optimized by Bayesian optimization. The CNN method was not only able to detect the presence of a phage but was also able to identify the phage type using unprocessed Raman spectra having high noise. In addition, a semi-supervised auto-encoder was utilized for differentiating healthy saliva from saliva spiked with phages thereby making it possible to detect the presence of phages in saliva samples.</p></div><div><h3><strong>Results</strong></h3><p>The CNN could identify the virus with an accuracy of 98.86% based on ten-fold cross-validation, precision of 98.8%, recall of 98.7%, and F1 score of 98.7%. The area under the curve of receiver operating characteristic curve was 0.99. Autoencoder was capable of differentiating healthy saliva from the virus spiked saliva with an accuracy of 99.7% in a semi-supervised manner. Thus, Raman spectroscopy coupled with machine learning approach was able to directly detect and identify the virus without consuming time for lengthy sample processing.</p></div><div><h3><strong>Conclusion</strong></h3><p>A robust method based on Raman spectroscopy coupled with machine learning may be capable of detection and identification of the virus even from the signal with low intensity and high noise. This label-free method is fast, sensitive, specific, and cost effective.</p></div>","PeriodicalId":73400,"journal":{"name":"Intelligent medicine","volume":"3 1","pages":"Pages 22-35"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45423753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Information technology and artificial intelligence support in management experiences of the pediatric designated hospital during the COVID-19 epidemic in 2022 in Shanghai","authors":"Yu Shi ,&nbsp;Jin Fu ,&nbsp;Mei Zeng ,&nbsp;Yanling Ge ,&nbsp;Xiangshi Wang ,&nbsp;Aimei Xia ,&nbsp;Weijie Shen ,&nbsp;Jiali Wang ,&nbsp;Weiming Chen ,&nbsp;Siyuan Jiang ,&nbsp;Xiaowen Zhai","doi":"10.1016/j.imed.2022.08.002","DOIUrl":"10.1016/j.imed.2022.08.002","url":null,"abstract":"<div><h3><strong>Objective</strong></h3><p>To describe the information technology and artificial intelligence support in management experiences of the pediatric designated hospital in the wave of COVID-19 in Shanghai.</p></div><div><h3><strong>Methods</strong></h3><p>We retrospectively concluded the management experiences at the largest pediatric designated hospital from March 1st to May 11th in 2022 in Shanghai. We summarized the application of Internet hospital, face recognition technology in outpatient department, critical illness warning system and remote consultation system in the ward and the structed electronic medical record in the inpatient system. We illustrated the role of the information system through the number and prognosis of patients treated.</p></div><div><h3><strong>Results</strong></h3><p>The COVID-19 designated hospitals were built particularly for critical patients requiring high-level medical care, responded quickly and scientifically to prevent and control the epidemic situation. From March 1st to May 11th, 2022, we received and treated 768 children confirmed by positive RT-PCR and treated at our center. In our management, we use Internet Information on the Internet Hospital, face recognition technology in outpatient department, critical illness warning system and remote consultation system in the ward, structed electronic medical record in the inpatient system. No deaths or nosocomial infections occurred. The number of offline outpatient visits dropped, from March to May 2022, 146,106, 48,379, 57,686 respectively. But the outpatient volume on the internet hospital increased significantly (3,347 in March 2022 <em>vs</em>. 372 in March 2021; 4,465 in April 2022 <em>vs</em>. 409 in April 2021; 4,677 in May 2022 <em>vs</em>. 538 in May 2021).</p></div><div><h3><strong>Conclusions</strong></h3><p>Information technology and artificial intelligence has provided significant supports in the management. The system might optimize the admission screening process, increases the communication inside and outside the ward, achieves early detection and diagnosis, timely isolates patients, and timely treatment of various types of children.</p></div>","PeriodicalId":73400,"journal":{"name":"Intelligent medicine","volume":"3 1","pages":"Pages 16-21"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9444255/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9077907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Guide for Authors","authors":"","doi":"10.1016/S2667-1026(23)00016-5","DOIUrl":"https://doi.org/10.1016/S2667-1026(23)00016-5","url":null,"abstract":"","PeriodicalId":73400,"journal":{"name":"Intelligent medicine","volume":"3 1","pages":"Pages 79-84"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49890713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-invasive cuffless blood pressure and heart rate monitoring using impedance cardiography","authors":"Sudipta Ghosh ,&nbsp;Bhabani Prasad Chattopadhyay ,&nbsp;Ram Mohan Roy ,&nbsp;Jayanta Mukherjee ,&nbsp;Manjunatha Mahadevappa","doi":"10.1016/j.imed.2021.11.001","DOIUrl":"10.1016/j.imed.2021.11.001","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;&lt;em&gt;&lt;strong&gt;Background&lt;/strong&gt;&lt;/em&gt;&lt;/h3&gt;&lt;p&gt;Continuous blood pressure (BP) monitoring provides additional information about how changes in BP may correlate with daily activities and sleep patterns. Recommendations from the American Heart Association and American College of Cardiology strongly suggest confirming a diagnosis of hypertension with continuous BP monitoring. Non-invasive and non-intrusive detection of haemodynamic parameters is emerging as a norm, based on self-monitoring wearable medical devices. Researchers have carried out several studies using non-invasive and continuous BP measurements as an alternative to conventional cuff-based measurements. In this work, we proposed a novel method for cuffless estimation of BP using impedance cardiography (ICG).&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;&lt;em&gt;&lt;strong&gt;Methods&lt;/strong&gt;&lt;/em&gt;&lt;/h3&gt;&lt;p&gt;We conducted a single-centre, cross-sectional study of 104 subjects (of whom 30 were categorized as controls and the remaining 74 as the disease group) at the Medical College and Hospital, Kolkata. The disease group consisted of patients with confirmed coronary artery disease, while the individuals in the control group were deemed to be healthy. All subjects underwent electrocardiogram recording by on-duty doctors in order to determine their health status. A custom-made device based on the principle of impedance plethysmography was designed to record impedance changes due to subjects’ peripheral blood flow. The device was used to record ICG signals. In this study, we developed a novel auto-adaptive algorithm based on ICG signals for non-invasive, cuffless, continuous monitoring of BP and heart rate. Separate mathematical models were developed for all the estimated parameters (BP and heart rate) for both the study groups (control and disease). The developed models were auto-adaptive and did not require subject-specific calibration. Performance indicators including, &lt;span&gt;&lt;math&gt;&lt;mi&gt;r&lt;/mi&gt;&lt;/math&gt;&lt;/span&gt;&lt;sup&gt;2&lt;/sup&gt;, error percentage, standard deviation, and mean difference were used to quantify the performance of the models.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;&lt;em&gt;&lt;strong&gt;Results&lt;/strong&gt;&lt;/em&gt;&lt;/h3&gt;&lt;p&gt;The ICG signal recorded by the device was used to extract features and compute the augmentation index. The calculated augmentation index values showed strong correlations with systolic BP (&lt;span&gt;&lt;math&gt;&lt;mrow&gt;&lt;mi&gt;r&lt;/mi&gt;&lt;mo&gt;=&lt;/mo&gt;&lt;mn&gt;0.99&lt;/mn&gt;&lt;/mrow&gt;&lt;/math&gt;&lt;/span&gt;, &lt;span&gt;&lt;math&gt;&lt;mrow&gt;&lt;mi&gt;P&lt;/mi&gt;&lt;mo&gt;&lt;&lt;/mo&gt;&lt;mn&gt;0.05&lt;/mn&gt;&lt;/mrow&gt;&lt;/math&gt;&lt;/span&gt;), diastolic BP (&lt;span&gt;&lt;math&gt;&lt;mrow&gt;&lt;mi&gt;r&lt;/mi&gt;&lt;mo&gt;=&lt;/mo&gt;&lt;mn&gt;0.95&lt;/mn&gt;&lt;/mrow&gt;&lt;/math&gt;&lt;/span&gt;, &lt;span&gt;&lt;math&gt;&lt;mrow&gt;&lt;mi&gt;P&lt;/mi&gt;&lt;mo&gt;&lt;&lt;/mo&gt;&lt;mn&gt;0.05&lt;/mn&gt;&lt;/mrow&gt;&lt;/math&gt;&lt;/span&gt;), and heart rate (&lt;span&gt;&lt;math&gt;&lt;mrow&gt;&lt;mi&gt;r&lt;/mi&gt;&lt;mo&gt;=&lt;/mo&gt;&lt;mn&gt;0.78&lt;/mn&gt;&lt;/mrow&gt;&lt;/math&gt;&lt;/span&gt;, &lt;span&gt;&lt;math&gt;&lt;mrow&gt;&lt;mi&gt;P&lt;/mi&gt;&lt;mo&gt;&lt;&lt;/mo&gt;&lt;mn&gt;0.05&lt;/mn&gt;&lt;/mrow&gt;&lt;/math&gt;&lt;/span&gt;). The models were also shown to have a high degree of accuracy for systolic and diastolic BP. Error margins were in the range &lt;span&gt;&lt;math&gt;&lt;mrow&gt;&lt;mo&gt;±&lt;/mo&gt;&lt;mn&gt;2.33&lt;/mn&gt;&lt;/mrow&gt;&lt;/math&gt;&lt;/","PeriodicalId":73400,"journal":{"name":"Intelligent medicine","volume":"2 4","pages":"Pages 199-208"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667102621001194/pdfft?md5=b16ce127324e618d0d7d1de5e97fe5b2&pid=1-s2.0-S2667102621001194-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45789404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expert recommendations on collection and annotation of otoscopy images for intelligent medicine","authors":"Yuexin Cai ,&nbsp;Junbo Zeng ,&nbsp;Liping Lan ,&nbsp;Suijun Chen ,&nbsp;Yongkang Ou ,&nbsp;Linqi Zeng ,&nbsp;Qintai Yang ,&nbsp;Peng Li ,&nbsp;Yubin Chen ,&nbsp;Qi Li ,&nbsp;Hongzheng Zhang ,&nbsp;Fan Shu ,&nbsp;Guoping Chen ,&nbsp;Wenben Chen ,&nbsp;Yahan Yang ,&nbsp;Ruiyang Li ,&nbsp;Anqi Yan ,&nbsp;Haotian Lin ,&nbsp;Yiqing Zheng","doi":"10.1016/j.imed.2022.01.001","DOIUrl":"10.1016/j.imed.2022.01.001","url":null,"abstract":"<div><p>Middle and outer ear diseases are common otological diseases worldwide. Otoscopy and otoendoscopy examinations are essential first steps in the evaluation of patients with otological diseases. Misdiagnosis often occurs when the doctor lacks experience in interpreting the results of otoscopy or otoendoscopy, leading to delays in treatment or complications. Using deep learning to process otoscopy images and developing otoscopic artificial-intelligence-based decision-making systems will become a significant trend in the future. However, the uneven quality of otoscopy images is among the major obstacles to development of such artificial intelligence systems, and no standardized process for data acquisition, and annotation of otoscopy images in intelligent medicine has yet been fully established. The standards for data storage and data management are unified with those of other specialties and are introduced in detail here. This expert recommendation criterion improved and standardized the collection and annotation procedures for otoscopy images and fills the current gap in otologic intelligent medicine; it would thus lay a solid foundation for the standardized collection, storage, and annotation of otoscopy images and the application of training algorithms, and promote the development of automatic diagnosis and treatment for otological diseases. The full text introduced image collection (including patient preparation, equipment standards, and image storage), image annotation standards, and quality control.</p></div>","PeriodicalId":73400,"journal":{"name":"Intelligent medicine","volume":"2 4","pages":"Pages 230-234"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667102622000043/pdfft?md5=268521b464b77c2b7597c161f801b8bb&pid=1-s2.0-S2667102622000043-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46231264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Applying data mining techniques to classify patients with suspected hepatitis C virus infection","authors":"Reza Safdari ,&nbsp;Amir Deghatipour ,&nbsp;Marsa Gholamzadeh ,&nbsp;Keivan Maghooli","doi":"10.1016/j.imed.2021.12.003","DOIUrl":"https://doi.org/10.1016/j.imed.2021.12.003","url":null,"abstract":"<div><h3><em><strong>Background</strong></em></h3><p>Hepatitis C virus (HCV) has a high prevalence worldwide, and the progression of the disease can cause irreversible damage to severe liver damage or even death. Therefore, developing prediction models using machine learning techniques is beneficial. This study was conducted to classify suspected patients with HCV infection using different classification models.</p></div><div><h3><em><strong>Methods</strong></em></h3><p>The study was conducted using a dataset derived from the University of California, Irvine (UCI) Machine Learning Repository. Since the HCV dataset was imbalanced, the synthetic minority oversampling technique (SMOTE) was applied to balance the dataset. After cleaning the dataset, it was divided into training and test data for developing six classification models. These six algorithms included the support vector machine (SVM), Gaussian Naïve Bayes (NB), decision tree (DT), random forest (RF), logistic regression (LR), and K-nearest neighbors (KNN) algorithm. The Python programming language was used to develop the classifiers. Receiver operating characteristic curve analysis and other metrics were used to evaluate the performance of the proposed models.</p></div><div><h3><em><strong>Results</strong></em></h3><p>After the evaluation of the models using different metrics, the RF classifier had the best performance among the six methods. The accuracy of the RF classifier was 97.29%. Accordingly, the area under the curve (AUC) for LR, KNN, DT, SVM, Gaussian NB, and RF models were 0.921, 0.963, 0.953, 0.972, 0.896, and 0.998, respectively, RF showing the best predictive performance.</p></div><div><h3><em><strong>Conclusion</strong></em></h3><p>Various machine learning techniques for classifying healthy and unhealthy patients were used in this study. Additionally, the developed models might identify the stage of HCV based on trained data.</p></div>","PeriodicalId":73400,"journal":{"name":"Intelligent medicine","volume":"2 4","pages":"Pages 193-198"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S266710262200002X/pdfft?md5=3cfd2b4dfcc0a2de358d480f072ee672&pid=1-s2.0-S266710262200002X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137088991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuroimaging perspective in targeted treatment for type 2 diabetes melitus and sleep disorders","authors":"Karen M. von Deneen ,&nbsp;Malgorzata A. Garstka","doi":"10.1016/j.imed.2022.05.003","DOIUrl":"10.1016/j.imed.2022.05.003","url":null,"abstract":"<div><p>Type 2 diabetes mellitus (T2DM) and sleep disorders (SD) have become important and costly health issues worldwide, particularly in China. Both are common diseases related to brain functional and structural abnormalities involving the hypothalamic-pituitary-adrenal (HPA) axis. The brains of individuals who suffer from both diseases simultaneously might be different compared to healthy individuals. This review assessed current neuroimaging findings to develop alternative targeted treatments for T2DM and SD. Relevant articles published between January 2002 and September 2021 were searched in PubMed and Web of Science databases. Generalized treatment methods for T2DM include dietary/weight-loss management, metformin or a combination of two non-insulin drugs, and melatonin for SD, though alternative therapies including electroacupuncture (EA) have been utilized in treating both of these diseases separately because they are convenient, affordable, and safe. Standard and alternative treatments for T2DM were somehow effective in treating SD. Neuroimaging studies of these disorders can achieve higher treatment efficacy by targeting brain areas, such as the hypothalamus (HYP), as visualized via diffusion tensor imaging (DTI), and functional magnetic resonance imaging (fMRI). DTI and fMRI can map the human brain and are utilized in many experiments. Thus, we propose that neuroimaging studies could be used in treatment of SD in T2DM.</p></div>","PeriodicalId":73400,"journal":{"name":"Intelligent medicine","volume":"2 4","pages":"Pages 209-220"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667102622000390/pdfft?md5=92cde2206db2a5e2d36eea2d839fa06b&pid=1-s2.0-S2667102622000390-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42693021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutritional and physical improvements in older adults through the DOREMI remote coaching approach: a real-world study","authors":"Federico Vozzi ,&nbsp;Filippo Palumbo ,&nbsp;Erina Ferro ,&nbsp;Karl Kreiner ,&nbsp;Franca Giugni ,&nbsp;Rachel Dutton ,&nbsp;Shirley Hall ,&nbsp;Daniele Musian ,&nbsp;Marina Parolini ,&nbsp;Patrizia Riso ,&nbsp;Oberdan Parodi","doi":"10.1016/j.imed.2022.04.001","DOIUrl":"10.1016/j.imed.2022.04.001","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;&lt;em&gt;&lt;strong&gt;Background&lt;/strong&gt;&lt;/em&gt;&lt;/h3&gt;&lt;p&gt;Malnutrition (excess or defect) and sedentariness act as an accelerator in the older people frailty process. A systemic solution has been developed to engage older people in a healthier lifestyle using serious games and food monitoring. The study aimed to evaluate protocol influence on variables related to unhealthy behaviors improving dietary habits through a remote nutritional coaching approach and stimulating the population to increase physical activity through Exergames.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;&lt;em&gt;&lt;strong&gt;Methods&lt;/strong&gt;&lt;/em&gt;&lt;/h3&gt;&lt;p&gt;Thirty-two subjects (25 Treatments and 7 Controls, aging 65–80 years), of which 15 (11 Treatments and 4 Controls) living in the UK (ACCORD and ExtraCare Villages placed in Shenley Wood (Milton Keynes), St. Crispin (Northampton), and Showell Court (Wolverhampton)) and 17 (14 Treatments and 3 Controls) in Italy (Genoa, Liguria), were recruited and characterized in terms of nutritional status, physical, somatometric, hemodynamic and biochemical measurements, and body composition. Participants were stimulated to adopt the Mediterranean dietary pattern, by a food diary diet-app, and perform regular physical activity, by the Exergame app, for three months. At the end of the trial, users underwent the same test battery. Data were tested for normality of distribution by the Shapiro-Wilk test. Comparisons between groups were performed at baseline by unpaired Student's &lt;em&gt;t&lt;/em&gt;-test for continuous variables, chi-square test, or Fisher's exact test for categorical variables. Analysis of Variance (ANOVA) for repeated measures was used to analyze the significance of changes over time between groups.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;&lt;em&gt;&lt;strong&gt;Results&lt;/strong&gt;&lt;/em&gt;&lt;/h3&gt;&lt;p&gt;At the end of the trial, significant reductions of systolic (15 mmHg, &lt;em&gt;P&lt;/em&gt; = 0.001), diastolic (5 mmHg, &lt;em&gt;P&lt;/em&gt; = 0.025), mean (10 mmHg, &lt;em&gt;P&lt;/em&gt; = 0.001) blood pressure, and rate-pressure product (RPP) (1,105 mmHg*bpm, &lt;em&gt;P&lt;/em&gt; = 0.017) values were observed in DOREMI users. A trend of improvement of physical performance by the short physical performance battery (SPPB) was observed for balance and walk subtests. A significant decrease (0.91 kg, &lt;em&gt;P&lt;/em&gt; = 0.043) in Body Mass Index (BMI) was observed in overweight subjects (BMI &gt;25 kg/m&lt;sup&gt;2&lt;/sup&gt;) after DOREMI intervention in the entire population. The Mini Nutritional Assessment (MNA) score (1, &lt;em&gt;P&lt;/em&gt; = 0.004) significantly increased after intervention, while waist measure (3 cm, &lt;em&gt;P&lt;/em&gt; &lt;0.001) significantly decreased in the DOREMI users. A reduction in glycated hemoglobin (Hb) was registered (0.20%, &lt;em&gt;P&lt;/em&gt; = 0.018) in the DOREMI UK users.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;&lt;em&gt;&lt;strong&gt;Conclusions&lt;/strong&gt;&lt;/em&gt;&lt;/h3&gt;&lt;p&gt;Improvement of healthy behavior by technological tools, providing feedback between user and remote coach and increasing user's motivation, appears potentially effective. This information and communication technologies (ICT) approach offers an","PeriodicalId":73400,"journal":{"name":"Intelligent medicine","volume":"2 4","pages":"Pages 181-192"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667102622000134/pdfft?md5=b38482bb3e373d20340a47ce05386bc5&pid=1-s2.0-S2667102622000134-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48679882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Guide for Authors","authors":"","doi":"10.1016/S2667-1026(22)00094-8","DOIUrl":"https://doi.org/10.1016/S2667-1026(22)00094-8","url":null,"abstract":"","PeriodicalId":73400,"journal":{"name":"Intelligent medicine","volume":"2 4","pages":"Pages 235-240"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667102622000948/pdfft?md5=b559266c22b8ee8c493e8b774c0ee805&pid=1-s2.0-S2667102622000948-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137089737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}