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Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology最新文献

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Neutrophil granulocyte function in vitro. Evaluation of a fluid-phase leucocyte-bacteria reaction system. 中性粒细胞体外功能的研究。白细胞-细菌液相反应体系的评价。
Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1974.TB02303.X
Christian Bender Koch
{"title":"Neutrophil granulocyte function in vitro. Evaluation of a fluid-phase leucocyte-bacteria reaction system.","authors":"Christian Bender Koch","doi":"10.1111/J.1699-0463.1974.TB02303.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1974.TB02303.X","url":null,"abstract":"A modified method for evaluation of human neutrophil granulocyte function in vitro, based upon the combined determination of total and intracellular surviving bacteria in a reaction system of leucocytes and Staphylococcus aureus, is described. Analysis of the system reveals a close relationship between the processes of ingestion and intraleucocytic killing on a functional level, and points towards dependence of intraleucocytic killing rate upon the rate of ingestion. Defects in intraleucocytic killing are disclosed readily by an increase in the number of surviving intracellular bacteria which will not be caused by increased ingestion under normal conditions. Greatly impaired ingestion will cause an increase in total surviving bacteria with a near normal number of intracellular surviving bacteria. On the basis of these studies it can be concluded that this type of method is particularly suitable for the detection of defects in intraleucocytic killing whereas defects in ingestion are less readily disclosed.","PeriodicalId":7323,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology","volume":"24 1","pages":"127-135"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84557242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Studies on Stachybotrys alternans. 3. Chromatographic separation and tissue culture toxicity test of Stachybotrys toxins. 水杨树的研究。3.石竹毒素的色谱分离及组织培养毒性试验。
Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1974.TB02285.X
E. Korpinen, M. Kurkinen, M. Nummi, T. Enari
{"title":"Studies on Stachybotrys alternans. 3. Chromatographic separation and tissue culture toxicity test of Stachybotrys toxins.","authors":"E. Korpinen, M. Kurkinen, M. Nummi, T. Enari","doi":"10.1111/J.1699-0463.1974.TB02285.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1974.TB02285.X","url":null,"abstract":"","PeriodicalId":7323,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology","volume":"23 1","pages":"7-11"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81856788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
PURIFICATION, ANTIBODY ACTIVITY AND ULTRASTRUCTURE OF SECRETORY AND HIGH‐POLYMER IgA 分泌型和高聚物IgA的纯化、抗体活性和超微结构
Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1970.TB04292.X
Björn Blotii
{"title":"PURIFICATION, ANTIBODY ACTIVITY AND ULTRASTRUCTURE OF SECRETORY AND HIGH‐POLYMER IgA","authors":"Björn Blotii","doi":"10.1111/J.1699-0463.1970.TB04292.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1970.TB04292.X","url":null,"abstract":"Simple methods for the purification of secretory and high-polymer serum IgA are described. Gel filtration on exceptionally tall agarose columns was an essential step in these purification procedures. The presence of s-IgA-albumin complexes was noted in some colostrum samples. These complexes could be dissociated by mild reduction. Colostral IgA and high-polymer serum IgA from individuals vaccinated with poliovirus contained virus-neutralizing antibodies in modest titres. The ultrastructure of secretory IgA resembled a wishbone and the mean dimensions of the molecule were approximately 125 A x 30 A. The ultrastructural findings are compatible with a molecular model in which two IgA monomers are superimposed upon each other in a close-packed state with the secretory piece inserted in the constant region of the α-chains. The high-polymer serum IgA studied was made up of four filamentous structures joined at a central point. The total span of the molecule was approximately 100 A and the dimensions of subunits protruding from the centre were 50 to 55 A x 20 A.","PeriodicalId":7323,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology","volume":"19 1","pages":"226-238"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78422888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunity to Ascaris suum. 3. The importance of the gut for immunity in mice. 对猪蛔虫免疫。3.肠道对小鼠免疫力的重要性。
Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1970.TB04285.X
E. Bindseil
{"title":"Immunity to Ascaris suum. 3. The importance of the gut for immunity in mice.","authors":"E. Bindseil","doi":"10.1111/J.1699-0463.1970.TB04285.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1970.TB04285.X","url":null,"abstract":"In one experiment mice were immunized by repeated oral inoculations with Ascaris suum eggs. Immune mice and controls were challenged in 2 ways, viz., orally with eggs and intravenously with in vitro hatched second-stage larvae of Ascaris suum. In a second experiment immune mice and controls were sacrificed 8 hrs after an oral challenge with eggs. It is concluded that the intestine is important for immunity against Ascaris suum, and that the defence mechanism is acting by interfering with the process of hatching and the larval penetration of the gut mucosa. It became evident from Experiment 1 that the large majority of the third-stage larvae detected in the lungs after oral challenge had not developed from second-stage larvae in the lungs, but was most likely coming from the liver.","PeriodicalId":7323,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology","volume":"1 1","pages":"183-90"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74645366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 16
STUDIES ONSTACHYBOTRYS ALTERNANS 研究双生植物的替代物
Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1974.TB02353.X
E. Korpinen
{"title":"STUDIES ONSTACHYBOTRYS ALTERNANS","authors":"E. Korpinen","doi":"10.1111/J.1699-0463.1974.TB02353.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1974.TB02353.X","url":null,"abstract":"Low doses of stachybotrys toxin were administered per os to groups of mice in early pregnancy. The toxic material was given either in the form of infected grain, liquid growth medium or partly purified toxin preparation. The administration took place mostly either as a single dose on the 3rd or 5th day of pregnancy or during a five-day period in the feed. The toxin amounts administered varied from 3 to 4000 tissue culture units (TCU), measured by the mouse fibroblast tissue culture test. The proportion of pregnant mice in all toxin treated groups was 70.7 per cent and that in the control group was 90.5 per cent. The difference is statistically significant. Statistically significant differences were also demonstrated in the frequency of dead, resorbed and stunted foetuses and in the average litter size of live normal foetuses between the control group and the groups administered 100–4000 TCU of the stachybotrys toxin. The results thus provide experimental evidence that stachybotrys toxin can affect detrimentally foetuses in doses low enough not to cause any definite clinical signs of illness in pregnant females. The histopathological study revealed uteroplacental haemorrhages in toxin treated animals. This finding may be indicative of the mechanism of action by toxin.","PeriodicalId":7323,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology","volume":"27 1","pages":"457-464"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91379664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hapten-carrier relationships in immunological unresponsiveness. II. Decrease of antibody affinity and specificity in B cell tolerance. 半抗原载体与免疫无反应的关系。2B细胞耐受性中抗体亲和力和特异性降低。
Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1974.TB02367.X
I. Seppälä
{"title":"Hapten-carrier relationships in immunological unresponsiveness. II. Decrease of antibody affinity and specificity in B cell tolerance.","authors":"I. Seppälä","doi":"10.1111/J.1699-0463.1974.TB02367.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1974.TB02367.X","url":null,"abstract":"Mice were rendered tolerant to a haptenic determinant NIP by cyclophosphamide treatment and subsequent multiple intraperitoneal injections of NIP coupled to mouse serum albumin. Control mice received no antigen. The mice were challenged with immunogenic NIP-conjugates 20 days after stopping the tolerance inducing treatment. The response to the hapten was reduced, while the response to the carrier was normal. A second challenge showed absence of memory cell development towards the hapten. To study antibody affinity in tolerance rats were rendered tolerant to NNP-human serum albumin and challenged later with the tolerogen. The rats developed very little anti-NNP antibodies until 3 months after the tolerance inducing treatment. Then the affinity of antibodies was low in the tolerant group. A partial tolerance lasted one year, which is remarkably long when compared to other works on the length of B cell tolerance. Tolerant animals had only weakly specific antibody to the tolerogen in contrast to the controls. Maturation of antibody affinity was paralleled by increase in specificity in the control rats.","PeriodicalId":7323,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology","volume":"30 1","pages":"567-76"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88275640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Mycoplasmosis: experimental pyelonephritis in rats; Demonstration of antibody in urine and serum. 支原体病:实验性大鼠肾盂肾炎尿和血清中抗体的证明。
Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology Pub Date : 1974-12-01
S Rosendal, A C Thomsen
{"title":"Mycoplasmosis: experimental pyelonephritis in rats; Demonstration of antibody in urine and serum.","authors":"S Rosendal, A C Thomsen","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7323,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology","volume":"82 6","pages":"895-8"},"PeriodicalIF":0.0,"publicationDate":"1974-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15633379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gas chromatography of bacterial whole cell methanolysates; IV. A procedure for fractionation and identification of fatty acids and monosaccharides of cellular structures. 细菌全细胞甲醇解物的气相色谱分析脂肪酸和细胞结构单糖的分离和鉴定方法。
Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology Pub Date : 1974-12-01
E Jantzen, K Bryn, K Bovre
{"title":"Gas chromatography of bacterial whole cell methanolysates; IV. A procedure for fractionation and identification of fatty acids and monosaccharides of cellular structures.","authors":"E Jantzen, K Bryn, K Bovre","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7323,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology","volume":"82 6","pages":"753-66"},"PeriodicalIF":0.0,"publicationDate":"1974-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15329095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gas chromatography of bacterial whole cell methanolysates; VI. Fatty acid composition of strains within Micrococcaceae;. 细菌全细胞甲醇解物的气相色谱分析微球菌科菌株的脂肪酸组成;
Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology Pub Date : 1974-12-01
E Jantzen, T Bergan, K Bovre
{"title":"Gas chromatography of bacterial whole cell methanolysates; VI. Fatty acid composition of strains within Micrococcaceae;.","authors":"E Jantzen, T Bergan, K Bovre","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7323,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology","volume":"82 6","pages":"785-98"},"PeriodicalIF":0.0,"publicationDate":"1974-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15633374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Purine metabolism in Neisseria meningitidis. 2. Utilization of exogenous adenosine, guanosine and inosine. 脑膜炎奈瑟菌嘌呤代谢。2. 外源性腺苷、鸟苷和肌苷的利用。
Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology Pub Date : 1974-12-01
S Jyssum
{"title":"Purine metabolism in Neisseria meningitidis. 2. Utilization of exogenous adenosine, guanosine and inosine.","authors":"S Jyssum","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7323,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology","volume":"82 6","pages":"885-94"},"PeriodicalIF":0.0,"publicationDate":"1974-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15329100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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