Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology最新文献_第4页

Pseudomonas aeruginosa infection in cystic fibrosis. Relationship between mucoid strains of Pseudomonas aeruginosa and the humoral immune response. 囊性纤维化中的铜绿假单胞菌感染。铜绿假单胞菌黏液菌株与体液免疫反应的关系。

Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1974.TB02365.X

N. Høiby

{"title":"Pseudomonas aeruginosa infection in cystic fibrosis. Relationship between mucoid strains of Pseudomonas aeruginosa and the humoral immune response.","authors":"N. Høiby","doi":"10.1111/J.1699-0463.1974.TB02365.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1974.TB02365.X","url":null,"abstract":"The occurrence of Pseudomonas aeruginosa in the respiratory tract of 70 cystic fibrosis patients and the occurrence of precipitins against Ps. aeruginosa in sera from the same patients have been investigated during one year by means of monthly bacteriological examinations of tracheal secretions and by means of crossed Immunoelectrophoresis of a polyvalent Ps. aeruginosa antigen against sera from the patients. The one-year period prevalence rate of patients harbouring Ps. aeruginosa was 64 per cent. In newly colonized patients and in intermittently colonized patients non-mucoid strains were predominating, whereas mucoid strains were predominating in chronically colonized patients. The occurrence of mucoid strains, especially in chronically colonized patients, was associated with a significantly higher number of precipitins against Ps. aeruginosa than the occurrence of non-mucoid strains. Males chronically colonized with mucoid strains presented a significantly higher number of precipitins than females chronically colonized with mucoid strains and the number of precipitins was correlated with the duration of the chronic colonization with Ps. aeruginosa in males in contrast to females. The results are in accordance with the hypothesis that mucoid substance could be a virulence factor because it might inhibit the opsonizing effect of the precipitins on the mucoid cells and the complement dependent lysis of the cells hereby favouring mucoid strains at the expense of non-mucoid strains in the respiratory tract of cystic fibrosis patients.","PeriodicalId":7323,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology","volume":"58 1","pages":"551-558"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84742192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 120

Delayed hypersensitivity and essential hypertension. Delayed hypersensitivity against arterial wall components as a pathogenetic factor in essential hypertension. 迟发性超敏反应和原发性高血压。对动脉壁成分的迟发性超敏反应是原发性高血压的一个发病因素。

Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1974.TB02349.X

F. Olsen

引用次数: 15

IMMUNOELECTROPHORETIC PATTERNS OF EXTRACTS FROM ALL ESCHERICHIA COLI O AND K ANTIGEN TEST STRAINS 所有大肠杆菌o和k抗原试验菌株提取物的免疫电泳图谱

Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1970.TB04300.X

F. Ørskov, I. Ørskov

引用次数: 2

The K antigens of Escherichia coli. Re-examination and re-evaluation of the nature of L antigens. 大肠杆菌的K抗原。L抗原性质的重新检查和重新评价。

Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1970.TB04346.X

I. Ørskov, F. Ørskov

引用次数: 16

UPTAKE AND RELEASE OF 3H‐MITOMYCIN C IN MOUSE P‐388 CELL CULTURES 3h -丝裂霉素c在小鼠p - 388细胞培养中的摄取和释放

Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1974.TB02322.X

Jon Ørstavik

{"title":"UPTAKE AND RELEASE OF 3H‐MITOMYCIN C IN MOUSE P‐388 CELL CULTURES","authors":"Jon Ørstavik","doi":"10.1111/J.1699-0463.1974.TB02322.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1974.TB02322.X","url":null,"abstract":"Mouse P-388 cells were grown in suspension culture and exposed to 3H-labelled mitomycin C for 1 hour. With concentrations from 0.5 to 50 μg of 3H-mitomycin C per ml cell culture, about 0.01 per cent of the radioactivity added was found in washed cells. Most of the intracellular antibiotic was present as cold acid soluble material, but significant amounts of tritium were found in the nucleic acid- and protein fractions. The ratio of 3H per weight unit was of the same order of magnitude for DNA and RNA, but substantially lower for cell protein. Double labelling experiments using 14C-thymidine and 3H-mitomycin C were carried out to study the specific loss of antibiotic from the cells during post-treatment incubation. Cold TCA soluble 3H-mitomycin C was rapidly released from the cells during the first hours after they had been transferred to non-radioactive growth medium. Loss of 3H-radioactivity from the RNA- and protein fractions roughly paralleled the loss of 14C radioactivity from the DNA fraction over a period of 3 days. The content of 3H-radioactivity in the DNA containing cell fraction increased during the first day of post-treatment incubation, followed by a substantial drop during the second day. This drop was far more extensive than the corresponding loss of 14C radioactivity. During the third day after exposure to mitomycin C the drops in 3H and 14C in the DNA fraction were not significantly different.","PeriodicalId":7323,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology","volume":"43 1","pages":"270-276"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78581308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endogenous incorporation of 32P in Neisseria meningitidis. 2. The effects of acetate, succinate, propionate and acetoacetate. 32P在脑膜炎奈瑟菌中的内源性掺入。2. 醋酸盐、琥珀酸盐、丙酸盐和醋酸盐的作用。

Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1970.TB04313.X

S. Jyssum, K. Jyssum

引用次数: 0

Epidemiological investigations of the respiratory tract bacteriology in patients with cystic fibrosis. 囊性纤维化患者呼吸道细菌学的流行病学调查。

Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1974.TB02364.X

N. Høiby

{"title":"Epidemiological investigations of the respiratory tract bacteriology in patients with cystic fibrosis.","authors":"N. Høiby","doi":"10.1111/J.1699-0463.1974.TB02364.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1974.TB02364.X","url":null,"abstract":"Seventy patients with cystic fibrosis treated as out-patients in a cystic fibrosis clinic have been followed during one year by monthly bacteriological examinations of tracheal secretions. The daily impression obtained in the laboratory is expressed by the mean point prevalence rate of Pseudomonas aeruginosa: 44 per cent, Staphylococcus aureus: 39 per cent, Haemophilus influenzae: 17 per cent, Diplococcus pneumoniae: 8 per cent, and miscellaneous other bacteria, mainly Enterobacteriaceae: 8 per cent. The fluctuations of the bacteriology are described by additional epidemiological terms: At one or more examinations during the study (period prevalence rate), 90 per cent of the patients harboured St. aureus, 64 per cent Ps. aeruginosa (mainly mucoid strains), 64 per cent H. influenzae, 37 per cent D. pneumoniae, and 30 per cent miscellaneous other bacteria, mainly Enterobacteriaceae. This pattern was found in all age groups with minor age-dependent modifications, especially as regards Enterobacteriaceae. Ps. aeruginosa was predominating as regards chronic colonization which reflects the most difficult therapeutic problems, the period prevalence rate being 39 per cent in contrast to St. aureus: 10 per cent, and H. influenzae: 1 per cent. St. aureus was predominating as regards new colonization and recolonization which reflect the problems of prevention, the incidence rate of new colonization and recolonization per risk group being 84 per cent, followed by H. influenzae: 62 per cent, Ps. aeruginosa: 43 per cent, and D. pneumoniae: 30 per cent. The results show that the bacteriological problems in cystic fibrosis are still considerable as regards therapy as well as prevention. Although many species may colonize the respiratory tracts of these patients, the main clinical problems concern Ps. aeruginosa and St. aureus; the reason why is discussed.","PeriodicalId":7323,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology","volume":"50 1","pages":"541-50"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85053584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 146

PROTEIN A – AN “INCOMPLETE” STAPHYLOCOCCAL AGGLUTINOGEN 蛋白a -一种“不完全”葡萄球菌凝集素原

Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1970.TB04278.X

G. Kronvall

引用次数: 0

Gas chromatography of bacterial whole cell methanolysates; VI. Fatty acid composition of strains within Micrococcaceae;. 细菌全细胞甲醇解物的气相色谱分析微球菌科菌株的脂肪酸组成;

Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1974.TB02376.X

E. Jantzen, T. Bergan, K. Bøvre

引用次数: 23

The ultrastructure of cultivable treponemes. 2. Treponema calligyrum, Treponema minutum and Treponema microdentium. 可培养密螺旋体的超微结构。2. 细螺旋体，细螺旋体和微牙螺旋体。

Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1974.TB02358.X

K. Hougen

{"title":"The ultrastructure of cultivable treponemes. 2. Treponema calligyrum, Treponema minutum and Treponema microdentium.","authors":"K. Hougen","doi":"10.1111/J.1699-0463.1974.TB02358.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1974.TB02358.X","url":null,"abstract":"Treponema phagedenis, Treponema vincentii, and Treponema refringens were studied in the electron microscope by means of negative staining and sectioning techniques. The length and width of the cells were within the same limits for all three strains examined. Statistical analysis, however, demonstrated a difference in the wavelengths of the cells. Organisms of T. phagedenis and T. vincentii had blunt ends and possessed cell wall surface layers in which a regular substructure was only occasionally revealed, while cells of T. refringens had tapered ends and a distinctly structured cell wall surface layer. Generally, cells of the strains investigated had 4–6 flagella inserted at each end. Two bundles of flagella, one from each end of the cell, wound around the organism and overlapped in the middle of the cell. The flagella with their insertion organelles were identical for the three strains studied. Two bundles of cytoplasmic tubules were detected in the interior of the treponemes after treatment with either sodium deoxycholate or Myxobacter AL-1 protease 1. The two bundles of cytoplasmic tubules overlapped in the middle of the cell. The results of the present morphological study are compared with results obtained by other investigators studying other characteristics of these strains and it is concluded that the three strains studied belong to three different species.","PeriodicalId":7323,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology","volume":"40 1","pages":"495-507"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88652724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12