Hamatologie und Bluttransfusion最新文献_第7页

[Various types of malignant lymphomas]. [各种恶性淋巴瘤]。

Hamatologie und Bluttransfusion Pub Date : 1976-01-01

引用次数: 0

Sequences and functions of Rous sarcoma virus RNA. 劳斯肉瘤病毒RNA的序列与功能。

Hamatologie und Bluttransfusion Pub Date : 1976-01-01 DOI: 10.1007/978-3-642-87524-3_34

P H Duesberg, L H Wang, K Beemon, S Kawai, H Hanafusa

{"title":"Sequences and functions of Rous sarcoma virus RNA.","authors":"P H Duesberg, L H Wang, K Beemon, S Kawai, H Hanafusa","doi":"10.1007/978-3-642-87524-3_34","DOIUrl":"https://doi.org/10.1007/978-3-642-87524-3_34","url":null,"abstract":"<p><p>A procedure has been developed to map the genetic elements of avian tumor virus RNA, which has a molecular weight of about 3 X 10(6) daltons and a poly(A) sequence at the 3' end. For this purpose, about 30 RNase T1-resistant oligonucleotides were ordered relative to the 3'-poly(A) terminus of the RNA, to construct an oligonucleotide map of viral RNAs. A cluster of seven envelope gene (env)-specific oligonucleotides, identified by their absence from the otherwise very similar oligonucleotide map of an envelope-defective deletion mutant (which lacks the major viral glycoprotein), mapped at a distance of 0.9 to 1.6 X 10(6) daltons from the poly(A) end of sarcoma virus RNA. A cluster of three sarcoma gene (src)-specific oligonucleotides, identified by their absence from the otherwise nearly identical oligonucleotide map of a transformation-defective deletion mutant mapped at a distance of 0.2 to 0.6 X 10(6) daltons from the poly(A) end of sarcoma virus RNA. The oligonucleotide maps of sarcoma viruses and of related deletion mutants were the same from the poly(A) end up to 0.2 X 10(6) daltons and included one terminal oligonucleotide, termed C, which is found in all avian tumor viruses tested so far. Preliminary mapping experiments ordering the src-specific and env-specific oligonucleotides of recombinants, selected for sarcoma and envelope genes of different parents, agree with those obtained by comparing maps of wild type viruses and deletion mutants. A partial genetic map consistent with these results suggests that the src gene maps between the env gene and the 3'-poly(A) end of viral RNA. This map reads: poly(A)-src-env-(pol, gag).</p>","PeriodicalId":73191,"journal":{"name":"Hamatologie und Bluttransfusion","volume":"19 ","pages":"327-40"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11405647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

[Radiotherapy of Hodgkin's disease]. [何杰金氏病的放射治疗]。

Hamatologie und Bluttransfusion Pub Date : 1976-01-01

K Musshoff

引用次数: 0

[Histologic classification and pathologic anatomy of lymphogranulomatosis]. [淋巴肉芽肿病的组织学分类及病理解剖]。

Hamatologie und Bluttransfusion Pub Date : 1976-01-01

R Fischer

引用次数: 0

Cellular subclasses in human leukemic hemopoiesis. 人白血病造血的细胞亚类。

Hamatologie und Bluttransfusion Pub Date : 1976-01-01 DOI: 10.1007/978-3-642-87524-3_4

J E Till, T W Mak, G B Price, J S Senn, E A McCulloch