{"title":"Toward a temperament-based approach to depression: implications for neurobiologic research.","authors":"H S Akiskal","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7274,"journal":{"name":"Advances in biochemical psychopharmacology","volume":"49 ","pages":"99-112"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18655697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Neuroactive steroid modulation of GABAA receptors.","authors":"R W Olsen, D W Sapp","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In summary, the discovery of neuroactive steroids has led to a new appreciation of endocrine-nervous system interactions. The modulation of GABAA receptors by steroid hormone metabolites has far-reaching physiological and pharmacological implications, including relevance to human psychiatric and neurological problems (Fig. 7): I. MECHANISM OF GENERAL ANESTHESIA (Alphaxalone) II. GABA TONE IN SOME REGIONS (e.g., caudate) III. ANTI-ANXIETY ACTIVITY: (Post-partum depression, premenstrual syndrome?) (New drugs?) IV. CHILDBIRTH V. ANTIEPILEPTIC ACTIVITY (New drugs?) VI. REGIONAL HETEROGENEITY (Receptor subtypes) VII. PARTIAL AGONISTS (Better clinical profile?) FIG. 7. Implications of GABAA receptor as a nongenomic CNS target of steroids.</p>","PeriodicalId":7274,"journal":{"name":"Advances in biochemical psychopharmacology","volume":"48 ","pages":"57-74"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18658085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Animal models of different anxiety states.","authors":"S E File","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7274,"journal":{"name":"Advances in biochemical psychopharmacology","volume":"48 ","pages":"93-113"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18655688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A Koukopoulos, D Reginaldi, G Minnai, G Serra, L Pani, F N Johnson
{"title":"The long term prophylaxis of affective disorders.","authors":"A Koukopoulos, D Reginaldi, G Minnai, G Serra, L Pani, F N Johnson","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7274,"journal":{"name":"Advances in biochemical psychopharmacology","volume":"49 ","pages":"127-47"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18655692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Animal models of mania.","authors":"G L Gessa, L Pani, G Serra, W Fratta","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7274,"journal":{"name":"Advances in biochemical psychopharmacology","volume":"49 ","pages":"43-66"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18655694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E Costa, J Auta, H Caruncho, A Guidotti, F Impagnatiello, C Pesold, D M Thompson
{"title":"A search for a new anticonvulsant and anxiolytic benzodiazepine devoid of side effects and tolerance liability.","authors":"E Costa, J Auta, H Caruncho, A Guidotti, F Impagnatiello, C Pesold, D M Thompson","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7274,"journal":{"name":"Advances in biochemical psychopharmacology","volume":"48 ","pages":"75-92"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18658087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pharmacological treatment of depression and comorbid anxiety disorders.","authors":"G B Cassano, S Michelini","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7274,"journal":{"name":"Advances in biochemical psychopharmacology","volume":"49 ","pages":"113-25"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18655691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Benzodiazepine receptor function in anxiety disorders.","authors":"A L Malizia, N J Coupland, D J Nutt","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7274,"journal":{"name":"Advances in biochemical psychopharmacology","volume":"48 ","pages":"115-33"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18658160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Depression and mania. From neurobiology to treatment. Introduction.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7274,"journal":{"name":"Advances in biochemical psychopharmacology","volume":"49 ","pages":"ix-x"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18655689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}