Arne Streitbürger, Jendrik Hardes, Nina Myline Engel
{"title":"[Surgical treatment of primary malignant bone tumors : Local therapeutic considerations with respect to extent of resection and reconstruction in a multimodal treatment concept].","authors":"Arne Streitbürger, Jendrik Hardes, Nina Myline Engel","doi":"10.1007/s00104-026-02579-x","DOIUrl":"10.1007/s00104-026-02579-x","url":null,"abstract":"<p><p>The modern treatment of primary bone sarcomas is integrated into a multimodal treatment concept consisting of systemic and local therapeutic modalities. Conventional chemotherapy plays the leading role in first line treatment. In terms of local treatment of the primary tumor, complete tumor removal (R0 resection) is the procedure of choice in a curative treatment concept. In Ewing's sarcoma, additive local radiotherapy must be taken into account in the surgical planning as well as the choice of reconstruction procedure. In a palliative treatment approach, an individual treatment adaptation must be made. Depending on the tumor site and individual parameters, different reconstruction procedures are available. The quality of tumor removal directly influences the local recurrence rate, overall prognosis and type of reconstruction. Due to the rarity of the disease and the necessary high degree of specialization of the disciplines involved, treatment of bone sarcomas is restricted to specialized centers.</p>","PeriodicalId":72588,"journal":{"name":"Chirurgie (Heidelberg, Germany)","volume":" ","pages":"860-866"},"PeriodicalIF":0.0,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Resection of locally advanced soft tissue sarcomas of the extremities : Surgical strategies to avoid postoperative complications].","authors":"Julian Kylies, Anna Duprée, Matthias Priemel","doi":"10.1007/s00104-026-02577-z","DOIUrl":"10.1007/s00104-026-02577-z","url":null,"abstract":"<p><p>Soft tissue sarcomas of the extremities are rare malignant tumors that constitute less than 1% of all malignant diseases. The aim of multimodal treatment is the complete surgical removal of the tumor into healthy tissue in the sense of an R0 resection. Due to the possible proximity to skin, blood vessels, nerves and bone, locally advanced sarcomas necessitate a specialized interdisciplinary treatment planning which leads to a complete resection of the sarcoma and also ensures a maximum preservation of function or limb. To achieve this, vascular surgical and plastic reconstructive interventions must be taken into consideration. Furthermore, postoperative complications, such as wound healing disorders, seromas and infections must be avoided in order not to delay the rehabilitation. This article summarizes the practice-oriented principles of the surgical treatment for locally advanced sarcomas of the extremities with a focus on the reduction of postoperative morbidity.</p>","PeriodicalId":72588,"journal":{"name":"Chirurgie (Heidelberg, Germany)","volume":" ","pages":"867-873"},"PeriodicalIF":0.0,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13687172/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148992692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Neoadjuvant treatment of MMR-proficient rectal cancer : Focus on cancer of the middle and lower third segments].","authors":"Sigmar Stelzner","doi":"10.1007/s00104-026-02560-8","DOIUrl":"10.1007/s00104-026-02560-8","url":null,"abstract":"<p><p>The chapter on \"neoadjuvant treatment of rectal cancer\" of the new level-3 guideline colorectal cancer from September 2025 describes treatment corridors for rectal cancer with different risks for local recurrence and metachronous distant metastasis. A tailored concept must be worked out in the local tumor board taking functional aspects and patient preference into consideration. A continuous monitoring of the patient must be ensured particularly for the watch and wait concept. Further study results are necessary to enable a more precise patient selection.</p>","PeriodicalId":72588,"journal":{"name":"Chirurgie (Heidelberg, Germany)","volume":" ","pages":"920-925"},"PeriodicalIF":0.0,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[When and how are pulmonary metastases surgically treated in sarcomas?]","authors":"Matthias Grott, Hauke Winter","doi":"10.1007/s00104-026-02578-y","DOIUrl":"10.1007/s00104-026-02578-y","url":null,"abstract":"<p><p>The resection of pulmonary metastases is a local treatment option for sarcomas to achieve complete remission (CR), to histologically obtain metastases and to collect tissue for further molecular pathological investigations. In selected patients with a controlled primary tumor and no evidence of extrathoracic tumor manifestations, a resection of lung metastases can be indicated in a multidisciplinary sarcoma board. The aim is the complete removal of all metastases (R0 resection) with simultaneous preservation of as much healthy lung tissue as possible. Adequate cardiopulmonary fitness for single-lung ventilation and lung resection is mandatory. Minimally invasive techniques, such as video-assisted and robotic-assisted thoracoscopy, which are primarily used for the removal of peripheral metastases adjacent to the pleura as well as an open approach are available for resection. All three procedures have no relevant morbidity and mortality. The evidence is based on retrospective case series demonstrating a survival benefit in selected patients. This article gives an overview of when and how pulmonary metastases should be surgically treated in sarcoma patients.</p>","PeriodicalId":72588,"journal":{"name":"Chirurgie (Heidelberg, Germany)","volume":" ","pages":"886-891"},"PeriodicalIF":0.0,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148984372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yazan Amin, Anke Mittelstädt, Maximilian Brunner, Robert Grützmann
{"title":"[Pancreatic trauma : Review of the diagnostic and therapeutic challenges].","authors":"Yazan Amin, Anke Mittelstädt, Maximilian Brunner, Robert Grützmann","doi":"10.1007/s00104-026-02600-3","DOIUrl":"https://doi.org/10.1007/s00104-026-02600-3","url":null,"abstract":"<p><p>Pancreatic trauma represents a rare but clinically relevant entity within abdominal trauma. It predominantly occurs in association with severe abdominal injuries and is diagnostically demanding due to the retroperitoneal position of the organ and the frequently unspecific clinical manifestations. The diagnosis is often delayed as initially only unspecific clinical signs are mostly present. Contrast-enhanced computed tomography is currently considered the gold standard in the initial diagnostics, whereby the sensitivity with respect to pancreatic injuries is limited, especially in the early phase. Magnetic resonance imaging (MRI with MR cholangiopancreatography, MRCP) and endoscopic retrograde CP provide valuable supplementary information for assessment of ductal involvement. The treatment approach depends on the severity of the injury according to the American Association for the Surgery of Trauma (AAST) classification, the integrity of the pancreatic duct and the presence of accompanying intra-abdominal injuries. Low-grade pancreatic lesions can frequently be treated conservatively but high-grade traumatic injuries and duct involvement usually require surgical or interventional measures. Despite progress in the diagnostics and treatment, pancreatic trauma is still associated with a high morbidity. An early diagnosis and an interdisciplinary management in specialized centers are decisive for the prognosis.</p>","PeriodicalId":72588,"journal":{"name":"Chirurgie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149302548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Astrid Bauschke, Michael Ardelt, Aladdin Ali-Deeb, Falk Rauchfuss, Oliver Rohland, Laura Schwenk, Utz Settmacher
{"title":"[Consequences from the reform of hospital structure for surgery: what does centralization offer university visceral surgery departments?]","authors":"Astrid Bauschke, Michael Ardelt, Aladdin Ali-Deeb, Falk Rauchfuss, Oliver Rohland, Laura Schwenk, Utz Settmacher","doi":"10.1007/s00104-026-02607-w","DOIUrl":"https://doi.org/10.1007/s00104-026-02607-w","url":null,"abstract":"<p><p>The centralization of complex surgical procedures at universities improves treatment quality and prognosis. Numerous studies have confirmed that this is accompanied by a reduction in the length of hospital stays and treatment costs. In addition to the positive impact on patient care, the universities' roles in teaching and research are also experiencing changes; however, risks and limitations should also be addressed. Without extensive cooperation with outpatient and inpatient partners regarding diagnostics, emergency care and the implementation of multimodal treatment under the coordination of university visceral surgery departments, the effects on visceral surgery training must also be considered, so as not to negatively affect the attractiveness of the surgical profession and to avoid staff turnover. Significant changes and restructuring regarding new logistics requirements are emerging. There are indications of significant changes and restructuring regarding new requirements for logistics, interdisciplinary cooperation with portal clinics and collaboration in the interdisciplinary tumor board, which cannot yet be fully assessed.</p>","PeriodicalId":72588,"journal":{"name":"Chirurgie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149240658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Multimodal outpatient prehabilitation during neoadjuvant chemotherapy prior to gastrectomy in advanced gastric cancer].","authors":"Mario Kaufmann, Christoph Reißfelder","doi":"10.1007/s00104-026-02604-z","DOIUrl":"https://doi.org/10.1007/s00104-026-02604-z","url":null,"abstract":"","PeriodicalId":72588,"journal":{"name":"Chirurgie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149186682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Multimodal treatment of locally advanced and oligometastatic esophageal cancer].","authors":"Nerma Crnovrsanin, Henrik Nienhüser","doi":"10.1007/s00104-026-02595-x","DOIUrl":"https://doi.org/10.1007/s00104-026-02595-x","url":null,"abstract":"<p><p>Esophageal cancer is one of the most striking examples of the success of multimodal treatment concepts in gastrointestinal oncology. For locally advanced, resectable adenocarcinoma, perioperative chemotherapy with the FLOT regimen has replaced neoadjuvant chemoradiotherapy according to CROSS following the ESOPEC trial and represents the current standard, whereas for squamous cell carcinoma neoadjuvant chemoradiotherapy followed by surgery remains established. Immunotherapy is expanding the treatment spectrum: adjuvant nivolumab is established for residual disease after neoadjuvant chemoradiotherapy (CheckMate-577); perioperative durvalumab combined with FLOT improves event-free survival in gastric and gastroesophageal junction cancer (MATTERHORN). The SANO trial demonstrated noninferiority of active surveillance versus standard esophagectomy with respect to 2‑year overall survival in clinical complete responders; however, a decision analytical model based on the SANO data published in 2026 suggests potential long-term advantages of standard resection. In oligometastatic disease, FLOT5/RENAISSANCE showed no overall survival benefit for supplementary surgical resection and in this situation patient selection remains the central challenge. Future strategies will concentrate more on biological criteria, with a more precise definition of oligometastatic constellations, integrated immunotherapy and emerging biomarkers such as circulating tumor DNA.</p>","PeriodicalId":72588,"journal":{"name":"Chirurgie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149186642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hans A Schlößer, Lars M Schiffmann, Hans F Fuchs, Christiane J Bruns
{"title":"[Modern concepts in the surgical treatment of esophageal cancer].","authors":"Hans A Schlößer, Lars M Schiffmann, Hans F Fuchs, Christiane J Bruns","doi":"10.1007/s00104-026-02591-1","DOIUrl":"https://doi.org/10.1007/s00104-026-02591-1","url":null,"abstract":"<p><p>The surgical treatment of esophageal cancer is still one of the most demanding surgical procedures with poor long-term survival and considerable perioperative morbidity and mortality. The McKeown and Ivor Lewis procedures have been described decades ago and are currently mainly applied in multimodal treatment settings. A systematic lymph node dissection is indispensable and prognostically relevant and is adapted to the primary localization of the tumor. The systematic approach to lymph node resection is discussed based on the Japanese classification of the anatomical lymph node location, whereby lymphatic oligometastasis is also specifically addressed. The use of modern techniques has already led to a substantial improvement in the results and the underlying surgical strategies can also be used for laparoscopic, thoracoscopic and robotic procedures. A reduction of perioperative morbidity by the use of minimally invasive procedures is well-established for the abdominal as well as the thoracic phase of the surgery. Innovative visualization systems for assessment of the vascularization or lymphatic drainage ducts and the use of artificial intelligence are expected to further improve safety and oncological precision of surgery for esophageal cancer.</p>","PeriodicalId":72588,"journal":{"name":"Chirurgie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149139570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Long-term phonation status after reconstruction of the recurrent laryngeal nerve].","authors":"Natia Kvirkvelia, Detlef K Bartsch","doi":"10.1007/s00104-026-02596-w","DOIUrl":"https://doi.org/10.1007/s00104-026-02596-w","url":null,"abstract":"","PeriodicalId":72588,"journal":{"name":"Chirurgie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149119225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}