发布求助
文献互助 智能选刊 最新文献

Case reports in internal medicine最新文献

筛选
英文 中文
Factor VII Deficiency in Systemic Primary Amyloidosis: A Rare Case 系统性原发性淀粉样变性缺乏因子7:一例罕见病例
Case reports in internal medicine Pub Date : 2018-12-09 DOI: 10.5430/CRIM.V5N4P28
F. Dursun, Erdal Akyar, G. Uygun, Z. Başlar, B. Çobanoğlu
{"title":"Factor VII Deficiency in Systemic Primary Amyloidosis: A Rare Case","authors":"F. Dursun, Erdal Akyar, G. Uygun, Z. Başlar, B. Çobanoğlu","doi":"10.5430/CRIM.V5N4P28","DOIUrl":"https://doi.org/10.5430/CRIM.V5N4P28","url":null,"abstract":"Introduction: Isolated and combined factor deficiencies are known to occur in systemic primary amyloidosis. The most common factor deficiency known in these cases is isolated factor X deficiency. Other factor deficiencies are relatively less frequent. Isolated factor VII deficiency occurs very rarely in cases of systemic primary amyloidosis.Case report: A 58-year-old male patient previously presenting to another health center with complaints of generalized edema, fatigue, and itching had proteinuria and then he was diagnosed with systemic primary amyloidosis after the renal biopsy for proteinuria etiology. The patient’s laboratory tests showed prolongation of prothrombin time and factor VII deficiency. The patient responded well to the treatment for primary amyloidosis and factor VII deficiency.Discussion: In cases of systemic primary amyloidosis, if the etiology of prolonged prothrombin time involves no liver disease, warfarin use, or malabsorption, physicians should always keep in mind rare factor deficiencies such as factor VII deficiency, along with common factor deficiencies.","PeriodicalId":72533,"journal":{"name":"Case reports in internal medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/CRIM.V5N4P28","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48141604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A case of normoprolactinemic galactorrhea following aneurysmal subarachnoid hemorrhage 动脉瘤性蛛网膜下腔出血并发正常泌乳素溢乳1例
Case reports in internal medicine Pub Date : 2018-12-06 DOI: 10.5430/CRIM.V6N1P8
E. Uy, K. Asadipooya
{"title":"A case of normoprolactinemic galactorrhea following aneurysmal subarachnoid hemorrhage","authors":"E. Uy, K. Asadipooya","doi":"10.5430/CRIM.V6N1P8","DOIUrl":"https://doi.org/10.5430/CRIM.V6N1P8","url":null,"abstract":"Galactorrhea is most commonly associated with elevated levels of prolactin; however, it does happen in individuals whose prolactin level is within normal range. Galactorrhea has been reported after neurosurgical procedures, cranial trauma or cerebral hemorrhage affecting the hypothalamus, pituitary or pituitary stalk, but these were associated with elevated levels of prolactin. In our knowledge, there has not been a case reported wherein a patient developed normoprolactinemic galactorrhea after an aneurysmal subarachnoid hemorrhage. The etiology and pathophysiology of normoprolactinemic galactorrhea have not been distinctly defined making this entity a diagnostic and therapeutic challenge for physicians.","PeriodicalId":72533,"journal":{"name":"Case reports in internal medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/CRIM.V6N1P8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42078750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biopsy utility in the workup of ANCA-associated vasculitis 活检在anca相关血管炎检查中的应用
Case reports in internal medicine Pub Date : 2018-12-04 DOI: 10.5430/CRIM.V6N1P5
C. Anjo, H. Campos, Sofia Narciso, G. Silva, F. Duarte
{"title":"Biopsy utility in the workup of ANCA-associated vasculitis","authors":"C. Anjo, H. Campos, Sofia Narciso, G. Silva, F. Duarte","doi":"10.5430/CRIM.V6N1P5","DOIUrl":"https://doi.org/10.5430/CRIM.V6N1P5","url":null,"abstract":"ANCA - associated Vasculitis (AAV) positive biopsy is supportive of vasculitis diagnosis, the aim of this manuscript is that renal biopsy is not always compulsory in the diagnosis and management of AAV. 79 years old, Caucasian women, admitted with AAV suspicion, MPO positive. A Microscopic polyangiitis with a pulmonary – renal syndrome was diagnosed after other AAV were excluded. Remission induction and maintenance therapy was made. In 6 months the patient presented a considerable improvement with lower MPO value, ESR and a stabilization of kidney function. Renal biopsy has to be performed in the majority of patients with the suspicion or renal AAV, although in this case it was not performed considering that the patient was on chronic anticoagulation and renal biopsy was not essential for the diagnosis. We suggest that renal biopsy is a valuable method in establishes the aetiology of kidney disease and that it could be dismissed in AAV with suggestive clinical presentation and low suspicion for secondary vasculitis.","PeriodicalId":72533,"journal":{"name":"Case reports in internal medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/CRIM.V6N1P5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48206406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Swyer-James-MacLeod Syndrome: A case report in an adult and review of the literature Swyer-James MacLeod综合征：一例成人病例报告及文献复习
Case reports in internal medicine Pub Date : 2018-10-29 DOI: 10.5430/CRIM.V5N4P23
E. Trejo, C. Le, G. Weinstein, Patrick Barr, M. Feldman
{"title":"Swyer-James-MacLeod Syndrome: A case report in an adult and review of the literature","authors":"E. Trejo, C. Le, G. Weinstein, Patrick Barr, M. Feldman","doi":"10.5430/CRIM.V5N4P23","DOIUrl":"https://doi.org/10.5430/CRIM.V5N4P23","url":null,"abstract":"Swyer-James-MacLeod Syndrome (SJMS) is a rare, unilateral lung disease represented by radiographic translucency of the lung parenchyma secondary to the diminution of the pulmonary vasculature and to the overdistention of the alveoli. It is an uncommon sequela of post-infectious bronchiolitis obliterans (BO) in childhood. Patients with SJMS are often diagnosed in childhood and typically present with recurrent respiratory tract infections. Symptoms during childhood can be mild or absent, leading to a delayed diagnosis in adulthood. SJMS is characterized by the destruction of the small bronchioles and agenesis or hypoplasia of the pulmonary arteries leading to hypoperfusion of the pulmonary parenchyma, resulting in characteristic chest imaging findings of unilateral hyperlucency or translucence.Swyer and James first described this syndrome in 1953. It is a rare disease that can be can be caused by an infection with adenoviruses (types 3, 7, or 21) or Bordetella pertussis, a foreign body in the airway and hydrocarbon inhalation. We present a case of SJMS in whom the adult patient had been misdiagnosed with chronic obstructive pulmonary disease (COPD). She was eventually diagnosed with SJMS based on chest x-ray and chest CT findings of unilateral lung hyperlucency, as well as with scintigraphic findings showing virtually absent perfusion to the left lower lobe of the lung.","PeriodicalId":72533,"journal":{"name":"Case reports in internal medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/CRIM.V5N4P23","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46929789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
“Heartbeat in the head”–An atypical presentation of Dural Arteriovenous Malformation “头部心跳”-硬脑膜动静脉畸形的非典型表现
Case reports in internal medicine Pub Date : 2018-10-24 DOI: 10.5430/CRIM.V5N4P19
Shekhawat Ravindra Singh, Lim Winston Eng Hoe, Yong Kok Pin, D. Silva, Sonu Kumar Sumit
{"title":"“Heartbeat in the head”–An atypical presentation of Dural Arteriovenous Malformation","authors":"Shekhawat Ravindra Singh, Lim Winston Eng Hoe, Yong Kok Pin, D. Silva, Sonu Kumar Sumit","doi":"10.5430/CRIM.V5N4P19","DOIUrl":"https://doi.org/10.5430/CRIM.V5N4P19","url":null,"abstract":"Pulsatile tinnitus is an uncommon presenting symptom and is perceived to be repetitively synchronous with the patient’s heartbeat. Prompt recognition of this rare symptom and subsequent early identification of the underlying etiology is essential for timely management to prevent potentially major complications. Here we highlight a case of a middle-aged female who presented with symptom of ‘heartbeat in the head’ and was later found to have left dural arteriovenous fistula.","PeriodicalId":72533,"journal":{"name":"Case reports in internal medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/CRIM.V5N4P19","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45540651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Case reports of unexplained weight loss in autoimmune central neurological syndromes with anti-GAD antibodies 应用抗GAD抗体治疗自身免疫性中枢神经系统综合征的不明原因体重减轻病例报告
Case reports in internal medicine Pub Date : 2018-09-28 DOI: 10.5430/CRIM.V6N2P5
J. Broadley, M. Monif
{"title":"Case reports of unexplained weight loss in autoimmune central neurological syndromes with anti-GAD antibodies","authors":"J. Broadley, M. Monif","doi":"10.5430/CRIM.V6N2P5","DOIUrl":"https://doi.org/10.5430/CRIM.V6N2P5","url":null,"abstract":"Glutamic acid decarboxylase (GAD) is becoming increasingly recognised as an antigenic target in autoimmune disorders of the central nervous system. There are currently no reports of weight loss being a manifestation in such disorders. We describe two cases of anti-GAD associated neurological disorders with profound and otherwise unexplained weight loss. Both patients had incomplete response to immunotherapy, as is becoming typical of these disorders. The variable disease associations of anti-GAD antibodies is incompletely understood, and leads us to question whether weight loss in these patients could possibly be immune-mediated.","PeriodicalId":72533,"journal":{"name":"Case reports in internal medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/CRIM.V6N2P5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47423853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Giant renal oncocytoma presenting with right flank pain and hematoma 巨大肾癌细胞瘤表现为右侧疼痛和血肿
Case reports in internal medicine Pub Date : 2018-09-27 DOI: 10.5430/CRIM.V5N4P13
Robert Zakhia El Doueihi, M. Bulbul
{"title":"Giant renal oncocytoma presenting with right flank pain and hematoma","authors":"Robert Zakhia El Doueihi, M. Bulbul","doi":"10.5430/CRIM.V5N4P13","DOIUrl":"https://doi.org/10.5430/CRIM.V5N4P13","url":null,"abstract":"Renal oncocytomas are benign tumors representing 3% to 7% of primary renal neoplasms. Oncocytomas are often asymptomatic, discovered incidentally on routine radiological imaging. We report a giant renal oncocytoma in a 68-year-old male with chronic kidney disease. Patient had right upper quadrant pain and hematoma. The mass was palpable on physical exam. CT scan showed a 16 cm × 14 cm right renal mass, consistent with renal cell carcinoma, no major adenopathy, no renal vein invasion. Right radical nephrectomy was performed and histological examination was consisted with oncocytoma.","PeriodicalId":72533,"journal":{"name":"Case reports in internal medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/CRIM.V5N4P13","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48119064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nonspecific interstitial pneumonia: A rare adverse reaction of atorvastatin 非特异性间质性肺炎:阿托伐他汀罕见的不良反应
Case reports in internal medicine Pub Date : 2018-09-27 DOI: 10.5430/CRIM.V5N4P16
Jack Xu, S. Verga, J. Stoll, Lauren Pioppo, E. Shanahan, W. Khan
{"title":"Nonspecific interstitial pneumonia: A rare adverse reaction of atorvastatin","authors":"Jack Xu, S. Verga, J. Stoll, Lauren Pioppo, E. Shanahan, W. Khan","doi":"10.5430/CRIM.V5N4P16","DOIUrl":"https://doi.org/10.5430/CRIM.V5N4P16","url":null,"abstract":"Introduction: Statins have been shown to effectively prevent both cardiovascular morbidity and mortality by inhibiting the hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase enzyme. Pulmonary complications are very rare, and can include pneumonitis, pleural effusion, and nonspecific interstitial pneumonia (NSIP). There have been very few previously documented cases of statin-induced fibrotic NSIP.Case report: We present a female with a history of hyperlipidemia on atorvastatin who presented with shortness of breath. Computed tomography scan of the chest revealed interstitial infiltrates with bilateral ground-glass opacities. She underwent a surgical lung biopsy which showed uniform fibrous alveolar septal thickening, scattered collections of alveolar macrophages and inflammation, along with areas of fibrosis. The findings were most suggestive of fibrotic NSIP. Atorvastatin was stopped and she was started on mycophenolic acid with improvement of her symptoms.Discussion: Although rare, the clinician should be aware of possible pulmonary complications of statin therapy. The exact mechanism of injury is unclear, however immunological or toxicological mechanisms are implicated. One case series of statin induced interstitial lung disease showed some improvement of dyspnea with systemic glucocorticoids and termination of statin therapy. Statins, specifically pravastatin, lovastatin, and simvastatin have been associated with drug induced pneumonitis and interstitial lung disease.","PeriodicalId":72533,"journal":{"name":"Case reports in internal medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/CRIM.V5N4P16","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48558850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Severe folate deficiency anemia associated with the use of a PARP inhibitor (olaparib) in a patient with fallopian tube cancer 输卵管癌患者使用PARP抑制剂(奥拉帕尼)相关的严重叶酸缺乏性贫血
Case reports in internal medicine Pub Date : 2018-09-27 DOI: 10.5430/CRIM.V6N1P1
B. Yohannan, K. McIntyre, M. Feldman
{"title":"Severe folate deficiency anemia associated with the use of a PARP inhibitor (olaparib) in a patient with fallopian tube cancer","authors":"B. Yohannan, K. McIntyre, M. Feldman","doi":"10.5430/CRIM.V6N1P1","DOIUrl":"https://doi.org/10.5430/CRIM.V6N1P1","url":null,"abstract":"Treatment of cancer patients with olaparib (PARP inhibitor) is associated with an increased risk of anemia, which is seen in a majority of treated patients. However, symptomatic anemia requiring transfusion is rare. Olaparib-induced anemia can be secondary to bone marrow suppression, hemolysis or folate deficiency. We report a case of new onset severe folic acid deficiency anemia in a patient with breast and relapsed fallopian tube cancer being treated with olaparib. Complete blood count on admission showed a hemoglobin of 4.2 g/dl and serum folate was undetectable (< 1.6 ng/ml; reference range 7-31.4 ng/ml). This is the second report of olaparib-induced folate deficiency anemia. She received three units packed red cell transfusion and parenteral folic acid supplementation and improved symptomatically. This case highlights the importance of recognizing folate deficiency as a reversible cause of anemia with PARP inhibitor therapy.","PeriodicalId":72533,"journal":{"name":"Case reports in internal medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/CRIM.V6N1P1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46454639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Apical ballooning (Takotsubo) syndrome in the setting of chronic alcohol-induced hyponatremia 慢性酒精性低钠血症患者的根尖球囊(Takotsubo)综合征
Case reports in internal medicine Pub Date : 2018-09-26 DOI: 10.5430/CRIM.V5N4P10
Y. Hailemariam, Olufolahan Carrena, D. Eshun, Henry E. Okafor
{"title":"Apical ballooning (Takotsubo) syndrome in the setting of chronic alcohol-induced hyponatremia","authors":"Y. Hailemariam, Olufolahan Carrena, D. Eshun, Henry E. Okafor","doi":"10.5430/CRIM.V5N4P10","DOIUrl":"https://doi.org/10.5430/CRIM.V5N4P10","url":null,"abstract":" Takotsubo cardiomyopathy is also known as stress induced cardiomyopathy and transient left ventricular apical ballooning syndrome. There have been few case reports where hyponatremia was implicated as a trigger for stress-induced cardiomyopathy. We report the unusual case of a 79-year-old African American woman without any discernible recent stressors who presented atypically with generalized fatigue and was found to have severe hyponatremia (from chronic alcohol use and thiazide diuretics) and significantly elevated Troponin. Her echocardiogram and cardiac catheterization revealed typical features of apical ballooning syndrome.","PeriodicalId":72533,"journal":{"name":"Case reports in internal medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/CRIM.V5N4P10","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44581288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信