Cardiovascular disorder and medicine最新文献

{"title":"Adenosine vs Regadenoson Pharmacologic Stress Differs in Women with Suspected Coronary Microvascular Dysfunction: A Report from the Women's Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction (WISE-CVD) Study.","authors":"Janet Wei, Sawan Jalnakupur, Sherwin Dela Cruz, Galen Cook Wiens, Manish Motwani, Xiao Zhang, John W Petersen, Puja K Mehta, Chrisandra Shufelt, Behzad Sharif, Eileen Handberg, George Sopko, Andre Rogatko, Carl J Pepine, Daniel S Berman, Louise E Thomson, C Noel Bairey Merz","doi":"10.31487/j.cdm.2019.01.01","DOIUrl":"10.31487/j.cdm.2019.01.01","url":null,"abstract":"<p><strong>Background: </strong>Stress cardiac magnetic resonance (CMR) imaging with myocardial perfusion reserve index (MPRI) measurement has emerged as a noninvasive method for assessing coronary microvascular dysfunction (CMD) in the absence of obstructive coronary artery disease (CAD). Pharmacologic stress with adenosine or regadenoson is typically used with comparable coronary vasodilation, but higher unadjusted MPRI has been reported with regadenoson in healthy men. This difference has not been assessed in symptomatic or healthy women.</p><p><strong>Methods: </strong>In a prospective cohort study, 139 symptomatic women with suspected CMD and no obstructive CAD underwent stress CMR and invasive coronary flow reserve (CFR) testing. Adenosine was the default vasodilator (n=99), while regadenoson was used if history of asthma or prior adenosine intolerance (n=40). Stress CMR was also performed in 40 age-matched healthy controls using adenosine (n=20) and regadenoson (n=20). Unpaired t-tests and analysis of covariance were performed to compare MPRI with adenosine and regadenoson in the symptomatic women and healthy controls.</p><p><strong>Results: </strong>Compared to regadenoson cases, adenosine cases had lower invasive CFR (2.64±0.62 vs 2.94±0.68, p=0.01) and pharmacologic heart rate change (28±16 vs 38±15 bpm, p=0.0008). Unadjusted MPRI was lower in the adenosine compared to regadenoson cases (1.73±0.38 vs 2.27±0.59, <i>p</i><0.0001). When adjusted for heart rate, rate-pressure-product, and invasive CFR, MPRI remained lower in the adenosine cases (<i>p</i><0.0001). Invasive CFR to adenosine correlated with adenosine MPRI (r 0.17, p=0.02) but not regadenoson MPRI (r -0.14, p=0.19). There was no significant difference in MPRI in the controls who received adenosine vs regadenoson (2.27±0.33 vs 2.38±0.44, p=0.36).</p><p><strong>Conclusion: </strong>In women undergoing stress CMR for suspected CMD, those who received adenosine had lower MPRI than those who received regadenoson. However, there were no differences in MPRI in the healthy controls. These findings suggest there may be physiologic differences in adenosine and regadenoson response in the coronary microcirculation of symptomatic women.</p>","PeriodicalId":72528,"journal":{"name":"Cardiovascular disorder and medicine","volume":"2019 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997839/pdf/nihms-1865295.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9106048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"« Doing our own thing » : la légende Postcard de Glasgow et l’attitude de la jeune Écosse","authors":"Laurence Estanove","doi":"10.4000/books.ms.1677","DOIUrl":"https://doi.org/10.4000/books.ms.1677","url":null,"abstract":"","PeriodicalId":72528,"journal":{"name":"Cardiovascular disorder and medicine","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88483370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Faire l’histoire d’un groupe de rock OTH, 1976-1991","authors":"T. Loué","doi":"10.4000/books.ms.1647","DOIUrl":"https://doi.org/10.4000/books.ms.1647","url":null,"abstract":"","PeriodicalId":72528,"journal":{"name":"Cardiovascular disorder and medicine","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81615934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Remerciements","authors":"P. Edwards, Élodie Grossi, P. Schor","doi":"10.4000/books.ms.1512","DOIUrl":"https://doi.org/10.4000/books.ms.1512","url":null,"abstract":"","PeriodicalId":72528,"journal":{"name":"Cardiovascular disorder and medicine","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83652381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"« Si l’on n’écrit pas notre histoire, ce sera, comme d’habitude, les rock-critics et les ennemis qui l’écriront »","authors":"P. Schor","doi":"10.4000/books.ms.1617","DOIUrl":"https://doi.org/10.4000/books.ms.1617","url":null,"abstract":"","PeriodicalId":72528,"journal":{"name":"Cardiovascular disorder and medicine","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79098925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Guérillas urbaines : la politique (sans posture) des premiers punks de San Francisco","authors":"Michael Stewart Foley","doi":"10.4000/BOOKS.MS.1657","DOIUrl":"https://doi.org/10.4000/BOOKS.MS.1657","url":null,"abstract":"HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignement et de recherche français ou étrangers, des laboratoires publics ou privés. Guérillas urbaines : la politique (sans posture) des premiers punks de San Francisco Michael Stewart Foley","PeriodicalId":72528,"journal":{"name":"Cardiovascular disorder and medicine","volume":"118 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82444569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Le fanzine DIY comme élément de structuration des réseaux punk","authors":"S. Étienne","doi":"10.4000/books.ms.1562","DOIUrl":"https://doi.org/10.4000/books.ms.1562","url":null,"abstract":"","PeriodicalId":72528,"journal":{"name":"Cardiovascular disorder and medicine","volume":"77 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91521199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Huligani dangereux : imaginaires « new punk wave » entre l’Europe de l’Est et l’Europe de l’Ouest","authors":"Djordje Sredanovic","doi":"10.4000/books.ms.1597","DOIUrl":"https://doi.org/10.4000/books.ms.1597","url":null,"abstract":"","PeriodicalId":72528,"journal":{"name":"Cardiovascular disorder and medicine","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88673515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment échapper à l’ennui : la scène punk suisse face au dilemme des mobilisations (1976-1982)","authors":"P. Raboud","doi":"10.4000/books.ms.1577","DOIUrl":"https://doi.org/10.4000/books.ms.1577","url":null,"abstract":"","PeriodicalId":72528,"journal":{"name":"Cardiovascular disorder and medicine","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85401866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Introduction. Punk is Dead, Long Live Punk and Post-Punk !","authors":"Paul M. Edwards, Élodie Grossi, P. Schor","doi":"10.4000/books.ms.1537","DOIUrl":"https://doi.org/10.4000/books.ms.1537","url":null,"abstract":"","PeriodicalId":72528,"journal":{"name":"Cardiovascular disorder and medicine","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85330339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}