Bulletin of the NYU hospital for joint diseases最新文献_第2页

Current concepts in the surgical management of acromioclavicular joint injuries. 肩锁关节损伤的外科治疗现状。

Bulletin of the NYU hospital for joint diseases Pub Date : 2012-01-01

David Epstein, Michael Day, Andrew Rokito

引用次数: 0

Three-and four-part proximal humerus fractures: evolution to operative care. 肱骨近端三段和四段骨折:向手术护理的演变。

Bulletin of the NYU hospital for joint diseases Pub Date : 2012-01-01

William Min, Roy I Davidovitch, Nirmal C Tejwani

引用次数: 0

Indications for operative fixation of distal radius fractures: a review of the evidence. 桡骨远端骨折手术固定的指征:证据回顾。

Bulletin of the NYU hospital for joint diseases Pub Date : 2012-01-01

Daniel K Laino, Nirmal Tejwani

引用次数: 0

Fractures of the proximal fifth metatarsal: keeping up with the Joneses. 第五跖骨近端骨折:跟上琼斯的步伐。

Bulletin of the NYU hospital for joint diseases Pub Date : 2012-01-01

Bryan C Ding, Justin M Weatherall, Kenneth J Mroczek, Steven C Sheskier

{"title":"Fractures of the proximal fifth metatarsal: keeping up with the Joneses.","authors":"Bryan C Ding, Justin M Weatherall, Kenneth J Mroczek, Steven C Sheskier","doi":"","DOIUrl":"","url":null,"abstract":"Fractures of the proximal fifth metatarsal are among the most common fractures of the foot. History, physical examination, and subsequent radiographic work-up can help with the diagnosis of such a fracture. Many fractures of the proximal fifth metatarsal can have an associated prodrome, thereby establishing a level of chronicity to the problem. Identification of the location of the fracture plane within the proximal fifth metatarsal can have prognostic implications in regards to fracture union rate and guide treatment options, due to the particular vascular anatomy of the region. Additional findings on physical exam, such as heel varus, can also impact prognosis and treatment options. Treatments can range from nonoperative to operative modalities, and time to weightbearing can vary. Within the realm of operative treatment, identification of certain parameters can aid in successful reduction and fixation of the fracture and thus impact healing. Careful consideration of the patient's particular constellation of social and professional needs, clinical and radiographic parameters, and acceptance of different options can help guide treatment recommendations in the individual patient.","PeriodicalId":72485,"journal":{"name":"Bulletin of the NYU hospital for joint diseases","volume":"70 1","pages":"49-55"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30835546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effective initial and long-term prednisone in doses of less than 5 mg/day to treat rheumatoid arthritis--documentation using a patient self-report Multidimensional Health Assessment Questionnaire (MDHAQ). 初始和长期剂量小于5mg /天的强的松治疗类风湿关节炎有效——使用患者自我报告多维健康评估问卷(MDHAQ)进行记录

Bulletin of the NYU hospital for joint diseases Pub Date : 2012-01-01

Theodore Pincus, Isabel Castrejón

{"title":"Effective initial and long-term prednisone in doses of less than 5 mg/day to treat rheumatoid arthritis--documentation using a patient self-report Multidimensional Health Assessment Questionnaire (MDHAQ).","authors":"Theodore Pincus, Isabel Castrejón","doi":"","DOIUrl":"","url":null,"abstract":"The efficacy of initial and long-term prednisone < 5 mg/ day in treatment of rheumatoid arthritis (RA) by one academic rheumatologist over 25 years from 1980 to 2004 is summarized. Patient responses were assessed using a multidimensional health assessment questionnaire (MDHAQ), completed by all patients at all visits in the infrastructure of care. A database was maintained of all visits, which included medications and scores for physical function, pain, patient global estimate of status, and routine assessment of patient index data (RAPID3), an index of these 3 measures. Prednisone doses were higher in patients with more severe MDHAQ/RAPID3 scores, as expected, although formal criteria were not used to determine the initial dose. Similar improvements were seen in clinical status over 12 months in patients treated with < 5 vs ≥ 5 mg/day prednisone and maintained for > 8 years. Adverse effects were primarily bruising and skin-thinning; levels of hypertension, diabetes, and cataracts were not higher than expected, including in 148 patients monitored over > 4 years, 75 over > 8 years. Prednisone at initial and long-term doses of < 5 mg/day appears acceptable and effective for many patients with RA at this time, although further clinical trials and long-term observational studies are needed to optimize treatment of patients with RA with low-dose prednisone. The data also illustrate that MDHAQ scores in usual clinical care can be used to document results of therapy over long periods with no extra work for the physician.","PeriodicalId":72485,"journal":{"name":"Bulletin of the NYU hospital for joint diseases","volume":"70 Suppl 1 ","pages":"14-20"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31139548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Update on treatment of psoriatic arthritis. 银屑病关节炎治疗的最新进展。

Bulletin of the NYU hospital for joint diseases Pub Date : 2012-01-01

Philip Mease

{"title":"Update on treatment of psoriatic arthritis.","authors":"Philip Mease","doi":"","DOIUrl":"","url":null,"abstract":"Some of this past year's key papers or abstracts on psoriatic arthritis (PsA) assessment and treatment are reviewed in this paper. Treatment begins with identification of the PsA patient. Several screening questionnaires have been developed to be used in dermatology and primary care settings to identify which patients with psoriasis have developed PsA as opposed to other common musculoskeletal problems, such as osteoarthritis and fibromyalgia, thus increasing case-finding and targeting referral. PsA can present in a heterogeneous manner, involving arthritis, enthesitis, dactylitis, spondylitis, and skin and nail disease. Measures of these individual domains have been developed for use in clinical trials and improved PsA-specific composite measures of these domains are being evaluated as well. A quantitative therapy target, Minimal Disease Activity criteria, has been developed by the GRAPPA group. Treatment recommendations have been published by EULAR and GRAPPA. Obesity is a risk factor for the development of PsA and may adversely influence treatment outcomes. Although pharmacologic treatment often begins with methotrexate, a recent study does not provide clear evidence of its effectiveness. Anti-TNF therapies remain the gold standard of effectiveness. New therapeutic options are potentially emerging including ustekinumab, abatacept, several IL-17 inhibitors, apremilast, JAK inhibitors, and possibly IL-6 inhibitors.","PeriodicalId":72485,"journal":{"name":"Bulletin of the NYU hospital for joint diseases","volume":" ","pages":"167-71"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31135901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Osteoporosis: an update. 骨质疏松症:最新进展。

Bulletin of the NYU hospital for joint diseases Pub Date : 2012-01-01

Stephen Honig, Gregory Chang

{"title":"Osteoporosis: an update.","authors":"Stephen Honig, Gregory Chang","doi":"","DOIUrl":"","url":null,"abstract":"The past year has been a dynamic one for clinicians and researchers with an interest in osteoporosis. This update will focus on the issue of the relationship between bisphosphonate treatment and atypical femoral fractures, highlight the advances in imaging techniques that are increasingly being studied as adjuncts to bone density testing, and explore recent evidence that suggests that osteoporosis medications may be linked to an increase in life expectancy. Since the first case reports describing unusual femur fractures in long term users of bisphosphonates began to appear, there has been great interest in identifying why and whether this class of drug can cause these atypical fractures. There have been a significant number of large studies that seem to suggest that these fractures do occur with an increased frequency among subjects who have used bisphosphonates over an extended period of time, but that these events are relatively rare. The occurrence of these fractures have helped to fashion new treatment regimens with periods of \"drug holidays\" often recommended to people with lower short-term and intermediate-term fracture risk. It is important to remind the reader that bisphosphonates prevent many typical hip and vertebral compression fractures, particularly in the higher risk elderly patient and that a rational balance be struck so that those in need of continued osteoporosis treatment receive it. Advances in imaging, such as high resolution MRI and peripheral micro CT scanners, are allowing investigators to non-invasively assess bone microarchitecture and bone stiffness of individuals as a means of trying to more accurately define those subjects who might be at increased risk of fracture and who might benefit from bone strengthening medication. Finally, this update will briefly review the emerging data that suggests that anti-resorptive medication may extend life expectancy beyond that which can be expected solely by reducing the incidence of future fractures.","PeriodicalId":72485,"journal":{"name":"Bulletin of the NYU hospital for joint diseases","volume":" ","pages":"140-4"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31138700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rheumatoid arthritis: circadian rhythms in disease activity, signs and symptoms, and rationale for chronotherapy with corticosteroids and other medications. 类风湿关节炎:疾病活动、体征和症状的昼夜节律，以及皮质类固醇和其他药物的时间疗法的基本原理

Bulletin of the NYU hospital for joint diseases Pub Date : 2012-01-01

Erhard Haus, Linda Sackett-Lundeen, Michael H Smolensky

{"title":"Rheumatoid arthritis: circadian rhythms in disease activity, signs and symptoms, and rationale for chronotherapy with corticosteroids and other medications.","authors":"Erhard Haus, Linda Sackett-Lundeen, Michael H Smolensky","doi":"","DOIUrl":"","url":null,"abstract":"Biological processes and functions at all hierarchical levels are organized in time as biological rhythms of discrete periods. Circadian (24-hour) rhythms, which are of direct importance to clinical medicine, are orchestrated by a set of clock genes of the master brain clock situated in the suprachiasmatic nuclei of the hypothalamus plus numerous subservient peripheral cellular clocks of all tissues and organs. Circadian rhythms are kept in step with the surrounding physical and social milieu by periodic external time cues, the most important one being the 24-hour environmental light-dark cycle. The circadian time structure gives rise to predictable-in-time day-night patterns in morbid and mortal events plus symptom occurrence and severity of common chronic conditions, including rheumatoid arthritis (RA). The circadian pattern of various cytokines and hormones in RA disease activity suggests a new treatment paradigm (i.e., chronotherapy-timing medications to 24-hour rhythms in disease pathophysiology) to improve desired outcomes. Since the 1950s, RA chronotherapy in the United States and Europe has involved several nonsteroid anti-inflammatory drugs (NSAIDs), certain disease modifying antirheumatic drugs (DMARDs), and various synthetic corticosteroid medications.","PeriodicalId":72485,"journal":{"name":"Bulletin of the NYU hospital for joint diseases","volume":"70 Suppl 1 ","pages":"3-10"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31139546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Corticosteroids as disease modifying drugs in rheumatoid arthritis treatment. 皮质类固醇在类风湿关节炎治疗中的作用。

Bulletin of the NYU hospital for joint diseases Pub Date : 2012-01-01

Yusuf Yazici

引用次数: 0

B-cell therapies for rheumatoid arthritis. 治疗类风湿性关节炎的 B 细胞疗法。

Bulletin of the NYU hospital for joint diseases Pub Date : 2012-01-01

Jose U Scher

引用次数: 0