BJUI compass最新文献

{"title":"Bone scan index rise prior to osteonecrosis of the jaw with bone-modifying agents in prostate cancer.","authors":"Masaru Tani, Koji Hatano, Takashi Kamiya, Masatoshi Konishi, Atsuki Matsukawa, Hiromu Horitani, Syunsuke Inoguchi, Tomohiro Kanaki, Akihiro Yoshimura, Yuki Horibe, Yutong Liu, Nesrine Sassi, Toshiki Oka, Yohei Okuda, Gaku Yamamichi, Yu Ishizuya, Takuji Hayashi, Yoshiyuki Yamamoto, Taigo Kato, Tadashi Watabe, Atsunari Kawashima, Kayako Isohashi, Norio Nonomura","doi":"10.1002/bco2.70212","DOIUrl":"https://doi.org/10.1002/bco2.70212","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the maximum bone scan index in the jaw (BSIJmax) before the development of clinical medication-related osteonecrosis of the jaw (MRONJ) in patients with prostate cancer.</p><p><strong>Methods: </strong>We retrospectively analysed 135 patients with prostate cancer and bone metastases who received bone-modifying agents (BMAs) between 2008 and 2025. Bone scintigraphy data were collected at baseline and during the BMA treatment. BSIJmax was calculated using computer-assisted diagnostic software (BONENAVI). Primary endpoints were BSIJmax in the maxilla and mandible before the clinical diagnosis of MRONJ, compared with baseline values. Secondary endpoints included area under the receiver operating characteristic curves (AUCs) for diagnosing MRONJ using BSIJmax in the maxilla and mandible.</p><p><strong>Results: </strong>Among 135 patients, 27 developed MRONJ during a median follow-up of 74 months (interquartile range, 41-124 months). Mandibular BSIJmax values before the clinical diagnosis of MRONJ were significantly higher than baseline values (0.090 vs. 0.027, <i>p</i> < 0.001), whereas maxillary values showed no significant change. The AUC for mandibular BSIJmax in diagnosing MRONJ was 0.803. A mandibular BSIJmax cut-off of 0.033 yielded a sensitivity and specificity of 85% and 71%, respectively, for the diagnosis of MRONJ.</p><p><strong>Conclusion: </strong>The mandibular BSIJmax increased before the clinical diagnosis of MRONJ. The incorporation of BSIJmax into bone scintigraphy may enable early detection of MRONJ and timely intervention in patients with prostate cancer receiving BMA therapy.</p>","PeriodicalId":72420,"journal":{"name":"BJUI compass","volume":"7 ","pages":"e70212"},"PeriodicalIF":1.9,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13124443/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147824262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perioperative factors influencing immediate and long-term continence after robot-assisted radical prostatectomy.","authors":"Till Rostalski, Anja Riediger, Axel Benner, Magdalena Görtz","doi":"10.1002/bco2.70207","DOIUrl":"https://doi.org/10.1002/bco2.70207","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to identify immediate and long-term predictors of postoperative urinary continence recovery after robotic-assisted radical prostatectomy (RARP) in a cohort of 1061 patients, enabling risk stratification and informing potentially modifiable perioperative strategies across patient subgroups.</p><p><strong>Patients and methods: </strong>Prospectively collected data from 1061 patients who underwent RARP between 2016 and 2021 at a single high-volume hospital were analysed. Urinary continence was evaluated immediately after surgery (<i>n</i> = 1061), after 1 year (<i>n</i> = 797) and after 3 years (<i>n</i> = 621). Multivariable ordinal logistic regression analyses were performed for each time point.</p><p><strong>Results: </strong>Immediately after catheter removal, 34.8% of patients were continent. Younger age, shorter catheterization duration, Retzius-sparing approach and nerve-sparing techniques were significant predictors (<i>p</i> < 0.05). After 1 year, the continence rate was 64.2%, with shorter catheterization duration and nerve-sparing techniques being significant. After 3 years, the continence rate was 79.1%. Only nerve-sparing techniques remained significantly associated with continence.</p><p><strong>Conclusion: </strong>Younger age, shorter catheterization, the Retzius-sparing approach and nerve-sparing surgical techniques were predictive for immediate continence after RARP and represent modifiable factors that should be considered where appropriate. For long-term continence, intraoperative nerve-sparing is particularly crucial.</p>","PeriodicalId":72420,"journal":{"name":"BJUI compass","volume":"7 ","pages":"e70207"},"PeriodicalIF":1.9,"publicationDate":"2026-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13100886/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147790500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Male stress urinary incontinence surgery in Australia: Temporal trends over two decades.","authors":"Omattage Mahasha Perera, Yam Ting Ho, Femi E Ayeni, Eric Chung, Vincent Tse, Devang Desai","doi":"10.1002/bco2.70205","DOIUrl":"https://doi.org/10.1002/bco2.70205","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to evaluate the national trends in the surgical management of male stress incontinence (SUI) in the Australian population over the 21st century.</p><p><strong>Methods: </strong>Data was sourced from the Australian Institute of Health and Welfare (AIHW) national morbidity database and Medicare Benefits Schedule (MBS) statistics reports. Annual data from financial years (FY) 2000/01 to 2022/23 was collected. Male SUI procedures are grouped into slings, paraurethral bulking agents (PBA) and artificial urinary sphincters (AUS). The annual procedural counts, revisions and yearly changes were obtained. The estimated subsidy burden was reported as AUD per capita (per 100 000 persons).</p><p><strong>Results: </strong>Between FY2000/01 and 2022/23, the aggregate number of male SUI procedures (excluding revisions) increased by 272% (from 288 to 1072). This is largely driven by the increase in AUS procedures, particularly amongst men aged 70-74 years. Male sling procedures demonstrated a substantial early increase followed by plateauing in recent years, while PBA declined over the same period. Revision procedures increased by 444% (from 41 to 223), largely due to AUS revisions and replacement. Over the same period, the estimated aggregate subsidy burden has increased from $13 749 to $53 269 per capita.</p><p><strong>Conclusion: </strong>The surgical management of male SUI in Australia has been transformative over the past two decades. Trends indicate an increase in male SUI procedures, particularly AUS procedures accompanied by an increase in AUS revision and replacement. These trends reflect both expanding surgical demand and durability of continence devices, which has subsequently led to a substantial increase in estimated subsidy burden.</p>","PeriodicalId":72420,"journal":{"name":"BJUI compass","volume":"7 ","pages":"e70205"},"PeriodicalIF":1.9,"publicationDate":"2026-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13100885/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147790503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Active migration technique in RIRS for 1- to 2-cm middle and upper ureteral stones in a prospective randomized controlled study.","authors":"Ping Liang, Qing-Lai Tang, Juan-Juan Mao, Yu-Xin Zhang, Yun-Peng Li, Xing-Zhu Zhou, Rong-Zhen Tao","doi":"10.1002/bco2.70204","DOIUrl":"https://doi.org/10.1002/bco2.70204","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to observe the efficacy and safety of the active migration technique and in situ lithotripsy technique in retrograde intrarenal surgery (RIRS) for patients with 1- to 2-cm middle and upper ureteral stones.</p><p><strong>Patients and methods: </strong>Two hundred seven patients were enrolled in the study, of which 103 included in the study group received active migration lithotripsy and 104 included in the control group received in situ lithotripsy. The primary study outcome was the stone-free rate (SFR) on the first postoperative day. Secondary outcomes included the total SFR 4 weeks postoperatively, operative time, reduction in the haemoglobin levels, the length of postoperative hospital stay, the incidence of ureteral stricture at 3-month postoperatively and any surgery-related complications.</p><p><strong>Results: </strong>There was no obvious difference between two groups in patients' demographics and preoperative clinical characteristics (<i>p</i> > 0.05). The operative time was significantly shorter in the study group than in the control group (57.1 vs. 62.5 min, <i>p</i> < 0.001). The study group also had significantly higher immediate and total SFRs (81.5% vs. 64.4%, <i>p</i> = 0.006, 90.3% vs. 77.9%, <i>p</i> = 0.015, respectively). At 3 months postoperatively, the incidence of ureteral stricture in the study was statistically lower than in the control group (1.0% vs. 6.7%, <i>p</i> = 0.032). Notablely, the overall complication rate was significantly lower in the study group than in the control group (<i>p</i> < 0.001).</p><p><strong>Conclusions: </strong>Our study provides evidence that the active migration technique, when combined with flexible and negative suction ureteral access sheath (FANS) in RIRS, results in a higher SFR and a lower complication rate than in situ lithotripsy for treating 1- to 2-cm middle and upper ureteral stones. The protocol for this study has been accepted by the Chinese Clinical Trial Registry (The registration number: ChiCTR2200056402; Date of registration: 03-06-2022).</p>","PeriodicalId":72420,"journal":{"name":"BJUI compass","volume":"7 ","pages":"e70204"},"PeriodicalIF":1.9,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13096931/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147790534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term intermittent catheterization: Safety and outcomes from a prospective observational study.","authors":"Peter Taffo, Gerard Amarenco, Carina Andersson, Nicola Morris, Jan Hörling","doi":"10.1002/bco2.70200","DOIUrl":"10.1002/bco2.70200","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this study was to evaluate long-term safety, urological complication rates and quality of life (QoL) associated with urethral intermittent catheterization (IC) over a 5-year follow-up in adult, established, experienced subjects with longstanding IC use.</p><p><strong>Patients and methods: </strong>Prospective, noninterventional, observational cohort study at three European sites. Adults (≥18 years) performing urethral IC with LoFric™ catheters for ≥6 years prior to enrolment were followed for 5 years. Outcomes included symptomatic urinary tract infections (UTIs), urethral strictures, bladder stones, prostatitis, epididymitis, patient-reported outcomes (PROs) and perception of catheters and IC. QoL, including pain and discomfort, anxiousness and depression, self-care and performing usual activities, was evaluated through the EQ 5DL questionnaire.</p><p><strong>Results: </strong>Ninety-eight participants were enrolled (April 2015-August 2018); 49 completed 5-year follow-up (PP). Median age at inclusion was 61 years; 69% were male. Median follow-up was 5 years; mean prior LoFric use was 13 years (range 6-30). Neurological conditions comprised 51% of underlying aetiologies. Across 5 years, there were no significant changes in UTI frequency, other urological complications, EQ-5D tariff, or PRO ratings. At baseline, 59% (PP) reported ≥1 UTI in the prior 12 months versus 55% at Year 5 (<i>p</i> = 0.8036); mean UTIs decreased from 3.93 to 3.63 (<i>p</i> = 0.5434). Urethral stricture reports rose from 6% to 12% (NS). EQ-5D tariff remained stable (mean 0.86 at inclusion and Year 5).</p><p><strong>Conclusions: </strong>In adults with more than a decade of prior IC experience, continued use of hydrophilic LoFric catheters over an additional 5 years was associated with unchanged complication rates and stable QoL and PROs, supporting the long-term safety of IC as a bladder management strategy.</p>","PeriodicalId":72420,"journal":{"name":"BJUI compass","volume":"7 4","pages":"e70200"},"PeriodicalIF":1.9,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13084324/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147724942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primary extragonadal germ cell tumours: Real-world data from a high-volume centre.","authors":"Marc Kidess, Marcus Hentrich, Franz Aschl, Oksana Chernova, Sebastian Beckstein, Peter Bojko, Sebastian Schulz, Julia Neitz, Julian Hermans, Yannic Volz, Benedikt Ebner, Patrick Keller, Maria Apfelbeck, Julian Marcon, Philipp Weinhold, Christian G Stief, Lennert Eismann, Michael Chaloupka","doi":"10.1002/bco2.70202","DOIUrl":"10.1002/bco2.70202","url":null,"abstract":"<p><strong>Objectives: </strong>To provide improved evidence for treatment recommendations, this study analysed real-world data on the characteristics, treatment and prognosis of primary extragonadal germ cell tumours (EGCTs), a very rare cancer entity that shares histological features with testicular GCTs (TGCT).</p><p><strong>Materials and methods: </strong>This retrospective study analysed data from 34 patients with mediastinal or retroperitoneal EGCTs treated at a high-volume centre between 2015 and 2025. Probability of overall survival (OS) and relapse-free survival (RFS) was assessed using Kaplan-Meier curves.</p><p><strong>Results: </strong>A primary retroperitoneal and primary mediastinal GCT was diagnosed in 23 (68%) and 11 (32%) patients, respectively. Median patient age was 41.1 years, and 62% were non-seminomatous in origin. Thirty-three (97%) patients received chemotherapy according to the IGCCCG prognostic group, and 15 (44%) underwent surgical intervention (4 primary RPLND, 8 post-chemotherapy RPLND, 3 secondary orchiectomy). Thirteen patients (44.9%) who completed chemotherapy experienced a relapse after a median of 0.79 years, and six of them died. In patients with primary mediastinal seminoma, 3-year RFS and OS were 100% as compared to 71% 3-year OS in patients with primary retroperitoneal non-seminoma and 46% 3-year RFS in patients with primary mediastinal non-seminoma.</p><p><strong>Conclusion: </strong>The prognosis for primary mediastinal seminoma appears favourable, while non-seminomatous EGCT shows poorer outcomes. Additionally, primary retroperitoneal seminomas demonstrate promising survival rates, whereas primary retroperitoneal non-seminomas demonstrate the lowest OS rates.</p>","PeriodicalId":72420,"journal":{"name":"BJUI compass","volume":"7 4","pages":"e70202"},"PeriodicalIF":1.9,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13084327/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147724954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Micro-ultrasound tissue echogenicity predicts prostate cancer grade.","authors":"Ailene E Corona, Dan Luca, Kian Kolahi Sohrabi, Kyla Grunden, William Chen, Pooneh J Sarmadian, Kevin J Walsh, Lorna Kwan, Qi Miao, Kyung Sung, Wayne G Brisbane","doi":"10.1002/bco2.70192","DOIUrl":"https://doi.org/10.1002/bco2.70192","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to evaluate the association between lesion echogenicity on micro-ultrasound (micro-US) and the presence and grade of prostate cancer.</p><p><strong>Patients and methods: </strong>We prospectively analysed 229 prostate lesions from 181 men undergoing micro-US-guided transperineal biopsy at UCLA. Lesions were visually graded as hyperechoic, isoechoic or hypoechoic relative to the central zone, which served as an internal reference due to its consistent tissue characteristics and low malignancy risk. Biopsy targeting was confirmed by visualizing the needle tract within the lesion. The primary outcome was the detection rate of Grade Group (GG) ≥ 2 cancer across echogenicity categories. Secondary analyses included associations with PSA density and MRI-derived apparent diffusion coefficient (ADC) values, given that ADC is associated with tissue cellularity. Statistical comparisons were performed using chi-square and Kruskal-Wallis tests, with post hoc pairwise analyses where appropriate.</p><p><strong>Results: </strong>GG ≥ 2 cancer detection rates increased with decreasing echogenicity: 22% in hyperechoic, 56.2% in isoechoic and 62.4% in hypoechoic lesions (<i>p</i> < 0.01). Hypoechoic lesions also exhibited a higher proportion of GG ≥ 3 cancers (<i>p</i> < 0.05). ADC values declined progressively from hyperechoic to hypoechoic lesions (median: 980, 851 and 751, respectively; <i>p</i> < 0.01), suggesting higher tissue cellularity. Regression analysis demonstrated no meaningful interaction between PRI-MUS and echogenicity. PSA density did not significantly differ among echogenicity groups.</p><p><strong>Conclusions: </strong>Lesion hypoechogenicity on micro-US is strongly associated with higher grade prostate cancer and lower ADC values, suggesting a link to tissue cellularity. These findings support the incorporation of echogenicity as a diagnostic marker within the micro-US PRI-MUS framework, potentially enhancing the accuracy of prostate cancer risk stratification.</p>","PeriodicalId":72420,"journal":{"name":"BJUI compass","volume":"7 4","pages":"e70192"},"PeriodicalIF":1.9,"publicationDate":"2026-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13077212/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147694134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of delayed elective urological surgery: A prospective observational study","authors":"Iva Simunovic,&nbsp;Hanna Zurl,&nbsp;Julia Altziebler,&nbsp;Conrad Leitsmann,&nbsp;Lukas Scheipner,&nbsp;Johannes Mischinger,&nbsp;Anna Mangge,&nbsp;Klara Pohl,&nbsp;Almut Frank,&nbsp;Alexandra Weiss,&nbsp;Gerhard Bachmaier,&nbsp;Sascha Ahyai,&nbsp;Marianne Leitsmann","doi":"10.1002/bco2.70197","DOIUrl":"10.1002/bco2.70197","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This study aimed to evaluate the psychological and physical impact of delayed elective urological surgeries, as limited surgical capacity has led to frequent cancellations and prolonged waiting times.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Patients and Methods</h3>\u0000 \u0000 <p>Between July 2023 and September 2025, patients admitted for elective surgery completed questionnaires including the NCCN Distress Thermometer, Severity Symptom Scale (SSS), PROMIS-10 and items on delay-related complications. Primary outcomes were psychological distress (NCCN ≥4), symptom burden (SSS ≥ 3) and PROMIS-10 Global Health T-scores.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 488 patients were analysed: 183 (37.5%) with confirmed/suspected oncological diagnoses and 304 (62.3%) non-oncological. Surgery was postponed in 51% of cases. Mean waiting time was 23.9 weeks (SD ± 19.6), longer for postponed patients (31.8 vs. 15.5 weeks; <i>p</i> &lt; 0.001) and more frequent among non-oncological patients (64.5% vs. 28.4%; <i>p</i> &lt; 0.001). Postponed patients reported higher symptom burden (SSS ≥ 3: 40.6% vs. 30.1%; <i>p</i> = 0.03) and lower Global Mental Health T-scores (43.9 ± 5.6 vs. 45.1 ± 5.3; <i>p</i> = 0.03). Regression analyses showed patients in the third and fourth waiting-time quartiles had higher SSS scores compared with the shortest quartile (<i>β</i> = 0.36, <i>p</i> = 0.02; <i>β</i> = 0.50, <i>p</i> = 0.001; overall model <i>p</i> = 0.01). Among postponed patients, 30.1% reported complications, most commonly pain (12.9%), urinary tract infection (11.7%), urinary retention (6.4%) and macroscopic haematuria (2.4%).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Prolonged waiting times and surgical postponements contribute to physical complaints and psychological distress. Persistent nursing shortages constrain capacity, emphasizing the need for long-term structural planning. Strengthening resources while maintaining patient-centred care is essential to prevent avoidable harm in elective urological surgery.</p>\u0000 </section>\u0000 </div>","PeriodicalId":72420,"journal":{"name":"BJUI compass","volume":"7 4","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13069355/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147678859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"European validation of the Barcelona magnetic resonance predictive model for significant prostate cancer detection in prostate biopsies","authors":"Juan Morote,&nbsp;Berta Miró,&nbsp;Lucas Regis,&nbsp;François Cousin,&nbsp;Patrick Duflot,&nbsp;Philippe Kolh,&nbsp;Alice Andalò,&nbsp;Nicola Gentili,&nbsp;Filippo Merloni,&nbsp;Andrea Prochowski Iamurri,&nbsp;Fabio Ferroni,&nbsp;Enrique Trilla,&nbsp;Olga Méndez","doi":"10.1002/bco2.70198","DOIUrl":"10.1002/bco2.70198","url":null,"abstract":"&lt;p&gt;Early detection of significant prostate cancer (sPCa) has notably improved with the widespread use of magnetic resonance imaging (MRI) and targeted biopsies. This advancement has contributed to the recommendation for PCa screening in the European Union. Nevertheless, PCa suspicion is still primarily based on a serum prostate-specific antigen (PSA) level greater than 3.0 ng/mL and/or a suspicious digital rectal examination (DRE). Prostate MRI is then requested to identify lesions suspected of harbouring sPCa, particularly when the Prostate Imaging-Reporting and Data System (PI-RADS) score is above 2. In such cases, both targeted biopsies of suspicious lesions and systematic biopsies are recommended, whereas prostate biopsy is typically avoided when the PI-RADS score is below 3. The European Association of Urology recommends the use of predictive models to reduce unnecessary prostate biopsies and the over-detection of insignificant prostate cancer (iPCa), especially in uncertain scenarios as PI-RADS 3 where the mean rate of sPCa detection is 20% and the overdetection of iPCa remains up to 50%.&lt;span&gt;&lt;sup&gt;1&lt;/sup&gt;&lt;/span&gt; Accessible web- or smartphone-based risk calculators are essential for integrating predictive models into routine practice for assessing individual sPCa likelihood. Furthermore, validating these predictive models in populations different from those used in their development is crucial to ensure generalizability and clinical reliability.&lt;span&gt;&lt;sup&gt;2&lt;/sup&gt;&lt;/span&gt;&lt;/p&gt;&lt;p&gt;The Barcelona MRI predictive model (BCN-MRI PM) was developed at a single academic institution within 1487 men suspected of having PCa, drawn from the sPCa opportunistic early detection program of Catalonia between 2016 and 2019. Two- to four-core MRI-transrectal ultrasound fusion targeted biopsies of PI-RADS lesions &gt;2 and/or 12-core systematic biopsies when PI-RADS &lt;3 were conducted via the transrectal route. This model, developed using logistic regression, incorporated age (years), family history of PCa (no vs. yes), type of prostate biopsy (initial vs. repeated), serum PSA level (ng/mL), DRE (normal vs. suspicious), MRI-derived prostate volume (mL) and PI-RADS v 2.0 (1–5) as independent predictive variables for sPCa. An initial external validation was conducted in 946 men, from two other institutions within the same metropolitan area, using the same criteria for PCa suspicion and diagnostic approach.&lt;span&gt;&lt;sup&gt;2&lt;/sup&gt;&lt;/span&gt; Subsequent validations of the BCN-MRI PM have been conducted in patients with symptomatic benign prostatic hyperplasia undergoing 5-alpha reductase inhibitors,&lt;span&gt;&lt;sup&gt;3&lt;/sup&gt;&lt;/span&gt; men classified with the PI-RADS v 2.1 and subjected to transperineal prostate biopsies&lt;span&gt;&lt;sup&gt;4&lt;/sup&gt;&lt;/span&gt; and men subjected to transperineal mapping biopsies of suspicious lesions and perilesional areas.&lt;span&gt;&lt;sup&gt;5&lt;/sup&gt;&lt;/span&gt;&lt;/p&gt;&lt;p&gt;Federated learning is emerging as a critical strategy for enabling the online validation of predictive models by utili","PeriodicalId":72420,"journal":{"name":"BJUI compass","volume":"7 4","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13066910/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147678764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to ‘Comparative analysis of early outcomes of the first 150 cases of posterior approach robotic-assisted radical prostatectomy and identification of the learning curve: A single-surgeon series’","authors":"","doi":"10.1002/bco2.70199","DOIUrl":"10.1002/bco2.70199","url":null,"abstract":"<p>\u0000 <span>Tay, LJ</span>, <span>Pan, HYC</span>, <span>Spurling, LJ</span>, <span>Dundee, P</span>. <span>Comparative analysis of early outcomes of the first 150 cases of posterior approach robotic-assisted radical prostatectomy and identification of the learning curve: A single-surgeon series</span>. <i>BJUI Compass.</i> <span>2025</span>; <span>6</span>(<span>7</span>):e70058. https://doi.org/10.1002/bco2.70058\u0000 </p><p>Authors Tay and Pan contributed equally and are co-first authors. This should have been noted in the published version.</p><p>We apologise for this error.</p>","PeriodicalId":72420,"journal":{"name":"BJUI compass","volume":"7 4","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13067972/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147678844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}