Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference最新文献
Yupeng Wu, Miguel Figueroa Hernandez, Tian Lei, Siddarth Jayakumar, Rohan R Lalapet, Alexandra Joshi-Imre, Mark E Orazem, Kevin J Otto, Stuart F Cogan
{"title":"The Effect of Physical Structural Properties on Electrochemical Properties of Ruthenium Oxide for Neural Stimulating and Recording Electrodes.","authors":"Yupeng Wu, Miguel Figueroa Hernandez, Tian Lei, Siddarth Jayakumar, Rohan R Lalapet, Alexandra Joshi-Imre, Mark E Orazem, Kevin J Otto, Stuart F Cogan","doi":"10.1109/EMBC53108.2024.10781914","DOIUrl":"10.1109/EMBC53108.2024.10781914","url":null,"abstract":"<p><p>Recently, there has been a growing interest in ruthenium oxide (RuOx) as an alternative mixed-conductor oxide to SIROF as an electrode coating. RuOx is recognized as a faradic charge-injection coating with high CSCc, long-term pulsing stability, and low impedance. We examined how the structural properties of sputter-deposited RuOx influence its electrochemical performance as an electrode coating for neural stimulation and recording. Thin film RuOx was deposited under various pressures: 5 mTorr, 15 mTorr, 30 mTorr, and 60 mTorr on wafer-based planar test structures. Electrochemical characterizations, including electrochemical impedance spectroscopy (EIS), cyclic voltammetry (CV), and voltage transient (VT), were employed. The structure of RuOx films was characterized by scanning electron microscope (SEM). Our findings revealed that the sputtering pressure significantly influences the growth of the RuOx film, subsequently affecting its electrochemical performance. The results indicate that the electrochemical performance of RuOx can be optimized by adjusting the deposition conditions to achieve a favorable balance between electronic and ionic conductivity.Clinical Relevance- This research underscores the potential for optimizing the structural properties of RuOx to enhance its electrochemical capabilities for neural stimulation and recording.</p>","PeriodicalId":72237,"journal":{"name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","volume":"2024 ","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143560042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yongjin Li, Binbin Wang, Xin Jiao, Mirabel Ewura Esi Acquah, Yunxia Zhu, Jun Jin, Xiaoyan Zhang, Dongyun Gu
{"title":"Muscle activation of lower limb during walking in elderly individuals with sarcopenia: A pilot study.","authors":"Yongjin Li, Binbin Wang, Xin Jiao, Mirabel Ewura Esi Acquah, Yunxia Zhu, Jun Jin, Xiaoyan Zhang, Dongyun Gu","doi":"10.1109/EMBC53108.2024.10782274","DOIUrl":"10.1109/EMBC53108.2024.10782274","url":null,"abstract":"<p><p>Sarcopenia is a muscle disease that can lead to a decrease in muscle mass and strength. Patients with sarcopenia usually have gait disorders and a higher risk of falls. At present, muscle activation of lower limb during walking in patients with sarcopenia is not clear, making it difficult to find effective rehabilitation training. In this study, we aim to investigate muscle activation of lower limb during walking in elderly individuals with sarcopenia. We collected surface EMG signals from the tibialis anterior (TA), lateral gastrocnemius (GL), rectus femoris (RF), and biceps femoris (BF) muscles during walking. Results showed that differences of muscle activation between sarcopenia patients and healthy elderly during walking are mainly reflected in the shank. Specially, RMS of TA was statistically significantly higher in sarcopenia patients during swing phase (p=0.005). Modulation index of GL was significantly higher in sarcopenia patients during pre-swing phase (p=0.01). Coactivation index of TA-GL was significantly lower in sarcopenia patients during single stance phase. A significant strong correlation was also observed between RMS of GL and step length (r=0.863, p=0.012) in sarcopenia patients. These results indicated that differences of muscle activation in shank may contribute to gait disorders in sarcopenia patients. It is recommended that exercise intervention strategies for sarcopenia patients should focus on shank muscles.</p>","PeriodicalId":72237,"journal":{"name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","volume":"2024 ","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Enhancing Medication Recommendation with Hierarchical Network and Patient Visit Histories.","authors":"Sawrawit Chairat, Apichat Sae-Ang, Kerdkiat Suvirat, Thammasin Ingviya, Sitthichok Chaichulee","doi":"10.1109/EMBC53108.2024.10781496","DOIUrl":"10.1109/EMBC53108.2024.10781496","url":null,"abstract":"<p><p>Prescribing medications is an essential part of patient care and requires precision and personalization in selection. Our study introduces a hierarchical medication recommendation system that aims to improve the prescribing process. We use FastText to embed medical contexts and employ a hierarchical attention-based model to manage the hierarchical structure of medication codes. The system takes input data from the current visit and the three previous visits to make recommendations. We trained and evaluated our model on 99,417 anonymized primary care outpatient visits. Our model achieved a mean average precision (mean AP) of 0.8724, 0.7419, 0.6805, and 0.6184 at the first, second, third, and fourth levels of the ATC system, respectively. We demonstrate that incorporating patient visit histories can improve predictions. Our results provide a solution to improve medication prescribing and suggest possible extensions for more comprehensive recommendations.</p>","PeriodicalId":72237,"journal":{"name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","volume":"2024 ","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143559368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Noa B Nuzov, Andrew R Crofton, Michael Markley, Chris A Flask, Ari M Blitz, Nicole A Pelot, Andrew J Shoffstall
{"title":"Gadolinium Solutions as Post-Mortem Magnetic Resonance Imaging Fiducial Markers and Intravascular Contrast Agents.","authors":"Noa B Nuzov, Andrew R Crofton, Michael Markley, Chris A Flask, Ari M Blitz, Nicole A Pelot, Andrew J Shoffstall","doi":"10.1109/EMBC53108.2024.10782569","DOIUrl":"10.1109/EMBC53108.2024.10782569","url":null,"abstract":"<p><p>Post-mortem human cadaveric imaging has numerous uses across medical research, education, and forensics. Magnetic resonance imaging (MRI) can illuminate gross anatomy and pathology without the need for dissection. However, post-mortem tissues suffer from relatively poor signal contrast and increased vascular porosity compared to living tissues. While clinical contrast agents enhance antemortem imaging, few have been optimized for post-mortem magnetic resonance (PMMR) imaging. Here, we systematically evaluated several simple and effective solutions as post-mortem fiducial markers and intravascular injection contrast agents. They demonstrated gadolinium concentration-dependent hyperintensity in several MRI sequences applied to gel phantoms and cadavers. The addition of gelatin increased hyperintensity and prevented vascular leakage. Ultimately, fiducial markers and post-mortem intravascular contrast provide validation for newly seen anatomy on high-resolution PMMR which can inform clinical practice.</p>","PeriodicalId":72237,"journal":{"name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","volume":"2024 ","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143559533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Multi-Contrast Translation-Based Registration Approach for Distortion Correction in DTI.","authors":"Ya Cui, Siyu Yuan, Zhenkui Wang, Li Tong, Jie Luo","doi":"10.1109/EMBC53108.2024.10781931","DOIUrl":"10.1109/EMBC53108.2024.10781931","url":null,"abstract":"<p><p>Correcting eddy currents and motion artifacts is crucial in Diffusion Tensor Imaging (DTI) preprocessing, traditionally managed through affine registration to an undistorted reference. However, the contrast variation across diffusion-weighted images complicates direct registration. To surmount this challenge, our study introduces a translation-based registration approach, utilizing 312 DTI datasets from the Human Connectome Project (HCP), including both b=0 and b=2000 volumes. We employed an advanced 3D Self-Attention Conditional Generative Adversarial Network (SC-GAN) for the synthesis of imaging data. This method allowed for the generation of synthesized b=2000 volumes, enhancing the distortion-correction process by facilitating efficient registration of distorted images. The results showed the translation network's effectiveness in synthesizing b=2000 volumes from real data, with these volumes serving as stable registration targets, particularly in limited directional data scenarios. The approach also effectively corrected eddy current and motion artifacts, aligning FA and FOD maps with gold standard results from FSL's eddy method, confirming the translation-based registration's efficacy in addressing cross-contrast registration challenges in DTI preprocessing.</p>","PeriodicalId":72237,"journal":{"name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","volume":"2024 ","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143558936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mst Rumana A Sumi, Masudul H Imtiaz, Stephanie Schuckers
{"title":"A Longitudinal Study on Fingerprint Recognition in Infants, Toddlers, and Children.","authors":"Mst Rumana A Sumi, Masudul H Imtiaz, Stephanie Schuckers","doi":"10.1109/EMBC53108.2024.10781797","DOIUrl":"10.1109/EMBC53108.2024.10781797","url":null,"abstract":"<p><p>Millions of children in developing countries face preventable deaths due to inadequate vaccination and malnutrition, in part due to insufficient monitoring and the absence of official identification. A reliable fingerprint recognition system can be a practical solution to address this issue. However, the scarcity of longitudinal fingerprint datasets for young children leads to unresolved questions regarding the earliest age for fingerprint biometric use, the frequency of enrollment required for reliable recognition, and the methods to accommodate age-related changes. A few recent studies introduced high-resolution fingerprint scanners and showed promising recognition performance for young children. However, these studies were conducted on a small dataset over a shorter period with limited diversity; further evaluation of their finding is essential. This study assessed the effectiveness of a high-resolution contactless scanner in a controlled, diverse longitudinal dataset of children (0-15 years). Our results indicate that infants can be enrolled at five days old and reliably recognized after two months with a TAR= 100% @ FAR = 0.1%, and children aged 4-15 years can be recognized after one year with a TAR= 98.72% @ FAR = 0.1%.</p>","PeriodicalId":72237,"journal":{"name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","volume":"2024 ","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143558930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Harikrishnan Muraleedharan Jalajamony, Soumadeep De, Renny Edwin Fernandez
{"title":"Clean Synthesis of ZnO-Au Nanoconjugate Inks for Bandgap Tuning Applications.","authors":"Harikrishnan Muraleedharan Jalajamony, Soumadeep De, Renny Edwin Fernandez","doi":"10.1109/EMBC53108.2024.10782882","DOIUrl":"10.1109/EMBC53108.2024.10782882","url":null,"abstract":"<p><p>This paper introduces a method for the scalable production of pristine nanoinks using ZnO-Au nanoconjugates, achieved through pulsed laser ablation in liquid (PLAL). This approach to nanoink synthesis offers adaptability in creating conjugates with adjustable bandgaps, suitable for direct inkjet printing applications. Our research is particularly centered on the clean fabrication of ZnO-Au conjugate nanoinks, investigating the capacity for bandgap modification in ZnO through the incorporation of gold nanoparticles of diverse sizes. The method highlights the crucial function of controlled laser ablation as a key technique for achieving precision and consistency in nanoparticle creation, thereby guaranteeing the superior quality and uniformity of the ZnO-Au nanoinks produced. Employing comprehensive characterization techniques, including SEM and EDS, we present the properties of the synthesized nanoconjugate inks.</p>","PeriodicalId":72237,"journal":{"name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","volume":"2024 ","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143559238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hugo M Martins, Matheus G Nogueira, Pedro Parik-Americano, Rafael T Moura, Arturo Forner-Cordero, Cristina P Camargo
{"title":"Impact of multidirectional vibratory feedback on posture control during standing and weight lifting: a pilot study.","authors":"Hugo M Martins, Matheus G Nogueira, Pedro Parik-Americano, Rafael T Moura, Arturo Forner-Cordero, Cristina P Camargo","doi":"10.1109/EMBC53108.2024.10782169","DOIUrl":"10.1109/EMBC53108.2024.10782169","url":null,"abstract":"<p><p>In this pilot study, we investigated the influence of vibratory feedback (VF) on postural control (PC) during frontal weight elevation and standing. We developed a multidirectional VF belt to provide feedback to the user on trunk inclination to correct the center of pressure (CoP) sway. CoP data were measured with a force plate, and user experience was collected through assessed questionnaires. Our findings suggest that VF contributes to a rapid return of the CoP to the Base of Support (BoS) during weight lifting(WL). However, VF may pose challenges during open-eyed conditions or with the addition of a compliant platform, potentially overwhelming users with proprioceptive stimuli and requiring increased attention. Although VF aids in postural correction near the support base and its periphery, individual factors such as user attention and sensitivity influence VF perception. Further studies with larger sample sizes are needed to validate these findings and explore the efficacy of VF in diverse postural control scenarios.</p>","PeriodicalId":72237,"journal":{"name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","volume":"2024 ","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143559616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Enhanced Transient Response of Ultrasound Neuromodulation Mediated by Large Conductance Mechanosensitive Ion Channel.","authors":"Xin Li, Guoying Zhang, Chenguang Zheng, Yutao Tian","doi":"10.1109/EMBC53108.2024.10782025","DOIUrl":"10.1109/EMBC53108.2024.10782025","url":null,"abstract":"<p><p>Ultrasound neuromodulation, a burgeoning field aimed at enhancing brain function and behavior, relies on the intricate electrophysiological responses of neurons driven by ion channel dynamics. However, achieving targeted and precise modulation with ultrasound poses a significant challenge. A hypothesis is that mechanosensitive (MS) ion channels may play a pivotal role in achieving the desired specificity in ultrasound effects. Our study involved augmenting MscL-G22S channel expression in specific areas of rats' hippocampus (HP) and primary visual cortex (V1) via AAV virus delivery. We recorded local field potentials (LFPs) to assess the modulation effect and identified distinct evoked-related potentials (ERPs) in regions overexpressing MscL-G22S channels under anesthesia. Notable variations in the amplitude of negative peaks were observed in the ERPs between HP and V1, highlighting a nuanced response to ultrasound stimulation. These results highlight the complexity and promise of MS channel-mediated neuromodulation, offering critical insights into the development of targeted ultrasound interventions to improve brain function.</p>","PeriodicalId":72237,"journal":{"name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","volume":"2024 ","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143559155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"EEG markers for anticipated difficulty of future visual task.","authors":"Zichen Song, Hiroshi Higashi, Shin Ishii","doi":"10.1109/EMBC53108.2024.10781596","DOIUrl":"10.1109/EMBC53108.2024.10781596","url":null,"abstract":"<p><p>Estimating human subjective difficulty in response to anticipated future events is an important technique for maintaining physical safety and mental well-being through effective load management. Towards to developing such techniques, we utilized electroencephalography (EEG) to estimate subjective difficulty associated with a forthcoming visual task. Our experiment entailed presenting participants with two visual stimuli during an initial anticipation period. These stimuli, being partial elements of the subsequent task, allowed participants to voluntarily anticipate the level of difficulty of the upcoming visual task. We found significant correlations between task difficulty and event-related potentials (N100, P400, and P600) as well as frequency bands (theta and beta) in the anticipation period. These results highlight the importance of gating mechanisms and working memory in anticipation period and provide a theoretical foundation for monitoring cognitive load.</p>","PeriodicalId":72237,"journal":{"name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","volume":"2024 ","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143559339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}