Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference最新文献

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Gadolinium Solutions as Post-Mortem Magnetic Resonance Imaging Fiducial Markers and Intravascular Contrast Agents. 钆溶液作为死后磁共振成像基准标记物和血管内造影剂。
Noa B Nuzov, Andrew R Crofton, Michael Markley, Chris A Flask, Ari M Blitz, Nicole A Pelot, Andrew J Shoffstall
{"title":"Gadolinium Solutions as Post-Mortem Magnetic Resonance Imaging Fiducial Markers and Intravascular Contrast Agents.","authors":"Noa B Nuzov, Andrew R Crofton, Michael Markley, Chris A Flask, Ari M Blitz, Nicole A Pelot, Andrew J Shoffstall","doi":"10.1109/EMBC53108.2024.10782569","DOIUrl":"10.1109/EMBC53108.2024.10782569","url":null,"abstract":"<p><p>Post-mortem human cadaveric imaging has numerous uses across medical research, education, and forensics. Magnetic resonance imaging (MRI) can illuminate gross anatomy and pathology without the need for dissection. However, post-mortem tissues suffer from relatively poor signal contrast and increased vascular porosity compared to living tissues. While clinical contrast agents enhance antemortem imaging, few have been optimized for post-mortem magnetic resonance (PMMR) imaging. Here, we systematically evaluated several simple and effective solutions as post-mortem fiducial markers and intravascular injection contrast agents. They demonstrated gadolinium concentration-dependent hyperintensity in several MRI sequences applied to gel phantoms and cadavers. The addition of gelatin increased hyperintensity and prevented vascular leakage. Ultimately, fiducial markers and post-mortem intravascular contrast provide validation for newly seen anatomy on high-resolution PMMR which can inform clinical practice.</p>","PeriodicalId":72237,"journal":{"name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","volume":"2024 ","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143559533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Multi-Contrast Translation-Based Registration Approach for Distortion Correction in DTI. 基于多对比翻译的DTI图像失真校正配准方法。
Ya Cui, Siyu Yuan, Zhenkui Wang, Li Tong, Jie Luo
{"title":"A Multi-Contrast Translation-Based Registration Approach for Distortion Correction in DTI.","authors":"Ya Cui, Siyu Yuan, Zhenkui Wang, Li Tong, Jie Luo","doi":"10.1109/EMBC53108.2024.10781931","DOIUrl":"10.1109/EMBC53108.2024.10781931","url":null,"abstract":"<p><p>Correcting eddy currents and motion artifacts is crucial in Diffusion Tensor Imaging (DTI) preprocessing, traditionally managed through affine registration to an undistorted reference. However, the contrast variation across diffusion-weighted images complicates direct registration. To surmount this challenge, our study introduces a translation-based registration approach, utilizing 312 DTI datasets from the Human Connectome Project (HCP), including both b=0 and b=2000 volumes. We employed an advanced 3D Self-Attention Conditional Generative Adversarial Network (SC-GAN) for the synthesis of imaging data. This method allowed for the generation of synthesized b=2000 volumes, enhancing the distortion-correction process by facilitating efficient registration of distorted images. The results showed the translation network's effectiveness in synthesizing b=2000 volumes from real data, with these volumes serving as stable registration targets, particularly in limited directional data scenarios. The approach also effectively corrected eddy current and motion artifacts, aligning FA and FOD maps with gold standard results from FSL's eddy method, confirming the translation-based registration's efficacy in addressing cross-contrast registration challenges in DTI preprocessing.</p>","PeriodicalId":72237,"journal":{"name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","volume":"2024 ","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143558936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Longitudinal Study on Fingerprint Recognition in Infants, Toddlers, and Children. 婴幼儿和儿童指纹识别的纵向研究。
Mst Rumana A Sumi, Masudul H Imtiaz, Stephanie Schuckers
{"title":"A Longitudinal Study on Fingerprint Recognition in Infants, Toddlers, and Children.","authors":"Mst Rumana A Sumi, Masudul H Imtiaz, Stephanie Schuckers","doi":"10.1109/EMBC53108.2024.10781797","DOIUrl":"10.1109/EMBC53108.2024.10781797","url":null,"abstract":"<p><p>Millions of children in developing countries face preventable deaths due to inadequate vaccination and malnutrition, in part due to insufficient monitoring and the absence of official identification. A reliable fingerprint recognition system can be a practical solution to address this issue. However, the scarcity of longitudinal fingerprint datasets for young children leads to unresolved questions regarding the earliest age for fingerprint biometric use, the frequency of enrollment required for reliable recognition, and the methods to accommodate age-related changes. A few recent studies introduced high-resolution fingerprint scanners and showed promising recognition performance for young children. However, these studies were conducted on a small dataset over a shorter period with limited diversity; further evaluation of their finding is essential. This study assessed the effectiveness of a high-resolution contactless scanner in a controlled, diverse longitudinal dataset of children (0-15 years). Our results indicate that infants can be enrolled at five days old and reliably recognized after two months with a TAR= 100% @ FAR = 0.1%, and children aged 4-15 years can be recognized after one year with a TAR= 98.72% @ FAR = 0.1%.</p>","PeriodicalId":72237,"journal":{"name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","volume":"2024 ","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143558930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clean Synthesis of ZnO-Au Nanoconjugate Inks for Bandgap Tuning Applications. 用于带隙调谐的ZnO-Au纳米共轭油墨的清洁合成。
Harikrishnan Muraleedharan Jalajamony, Soumadeep De, Renny Edwin Fernandez
{"title":"Clean Synthesis of ZnO-Au Nanoconjugate Inks for Bandgap Tuning Applications.","authors":"Harikrishnan Muraleedharan Jalajamony, Soumadeep De, Renny Edwin Fernandez","doi":"10.1109/EMBC53108.2024.10782882","DOIUrl":"10.1109/EMBC53108.2024.10782882","url":null,"abstract":"<p><p>This paper introduces a method for the scalable production of pristine nanoinks using ZnO-Au nanoconjugates, achieved through pulsed laser ablation in liquid (PLAL). This approach to nanoink synthesis offers adaptability in creating conjugates with adjustable bandgaps, suitable for direct inkjet printing applications. Our research is particularly centered on the clean fabrication of ZnO-Au conjugate nanoinks, investigating the capacity for bandgap modification in ZnO through the incorporation of gold nanoparticles of diverse sizes. The method highlights the crucial function of controlled laser ablation as a key technique for achieving precision and consistency in nanoparticle creation, thereby guaranteeing the superior quality and uniformity of the ZnO-Au nanoinks produced. Employing comprehensive characterization techniques, including SEM and EDS, we present the properties of the synthesized nanoconjugate inks.</p>","PeriodicalId":72237,"journal":{"name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","volume":"2024 ","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143559238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhanced Transient Response of Ultrasound Neuromodulation Mediated by Large Conductance Mechanosensitive Ion Channel. 大电导机械敏感离子通道介导的超声神经调节瞬态响应增强。
Xin Li, Guoying Zhang, Chenguang Zheng, Yutao Tian
{"title":"Enhanced Transient Response of Ultrasound Neuromodulation Mediated by Large Conductance Mechanosensitive Ion Channel.","authors":"Xin Li, Guoying Zhang, Chenguang Zheng, Yutao Tian","doi":"10.1109/EMBC53108.2024.10782025","DOIUrl":"10.1109/EMBC53108.2024.10782025","url":null,"abstract":"<p><p>Ultrasound neuromodulation, a burgeoning field aimed at enhancing brain function and behavior, relies on the intricate electrophysiological responses of neurons driven by ion channel dynamics. However, achieving targeted and precise modulation with ultrasound poses a significant challenge. A hypothesis is that mechanosensitive (MS) ion channels may play a pivotal role in achieving the desired specificity in ultrasound effects. Our study involved augmenting MscL-G22S channel expression in specific areas of rats' hippocampus (HP) and primary visual cortex (V1) via AAV virus delivery. We recorded local field potentials (LFPs) to assess the modulation effect and identified distinct evoked-related potentials (ERPs) in regions overexpressing MscL-G22S channels under anesthesia. Notable variations in the amplitude of negative peaks were observed in the ERPs between HP and V1, highlighting a nuanced response to ultrasound stimulation. These results highlight the complexity and promise of MS channel-mediated neuromodulation, offering critical insights into the development of targeted ultrasound interventions to improve brain function.</p>","PeriodicalId":72237,"journal":{"name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","volume":"2024 ","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143559155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
EEG markers for anticipated difficulty of future visual task. 预测未来视觉任务难度的脑电图标记。
Zichen Song, Hiroshi Higashi, Shin Ishii
{"title":"EEG markers for anticipated difficulty of future visual task.","authors":"Zichen Song, Hiroshi Higashi, Shin Ishii","doi":"10.1109/EMBC53108.2024.10781596","DOIUrl":"10.1109/EMBC53108.2024.10781596","url":null,"abstract":"<p><p>Estimating human subjective difficulty in response to anticipated future events is an important technique for maintaining physical safety and mental well-being through effective load management. Towards to developing such techniques, we utilized electroencephalography (EEG) to estimate subjective difficulty associated with a forthcoming visual task. Our experiment entailed presenting participants with two visual stimuli during an initial anticipation period. These stimuli, being partial elements of the subsequent task, allowed participants to voluntarily anticipate the level of difficulty of the upcoming visual task. We found significant correlations between task difficulty and event-related potentials (N100, P400, and P600) as well as frequency bands (theta and beta) in the anticipation period. These results highlight the importance of gating mechanisms and working memory in anticipation period and provide a theoretical foundation for monitoring cognitive load.</p>","PeriodicalId":72237,"journal":{"name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","volume":"2024 ","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143559339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Proxy-based Masking Module for Revealing Relevance of Characteristics in Motor Imagery. 基于代理的掩蔽模块揭示运动意象中相关特征。
Hyeon-Taek Han, Sung-Jin Kim, Dae-Hyeok Lee, Seong-Whan Lee
{"title":"Proxy-based Masking Module for Revealing Relevance of Characteristics in Motor Imagery.","authors":"Hyeon-Taek Han, Sung-Jin Kim, Dae-Hyeok Lee, Seong-Whan Lee","doi":"10.1109/EMBC53108.2024.10782698","DOIUrl":"10.1109/EMBC53108.2024.10782698","url":null,"abstract":"<p><p>Brain-computer interface (BCI) has been developed for communication between users and external devices by reflecting users' status and intentions. Motor imagery (MI) is one of the BCI paradigms for controlling external devices by imagining muscle movements. MI-based EEG signals generally tend to contain signals with sparse MI characteristics (sparse MI signals). When conducting domain adaptation (DA) on MI signals with sparse MI signals, it could interrupt the training process. In this paper, we proposed the proxy-based masking module (PMM) for masking sparse MI signals within MI signals. The proposed module was designed to suppress the amplitude of sparse MI signals using the negative similarity-based mask generated between the proxy of rest signals and the feature vectors of MI signals. We attached our proposed module to the conventional DA methods (i.e., the DJDAN, the MAAN, and the DRDA) to verify the effectiveness in the cross-subject environment on dataset 2a of BCI competition IV. When our proposed module was attached to each conventional DA method, the average accuracy was improved by much as 4.67 %, 0.76 %, and 1.72 %, respectively. Hence, we demonstrated that our proposed module could emphasize the information related to MI characteristics. The code of our implementation is accessible on GitHub.<sup>1</sup>.</p>","PeriodicalId":72237,"journal":{"name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","volume":"2024 ","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143559899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
3D-Printed Scaffold Mimicking IBD Gut Microenvironments: An In Vitro Model for Bacterial Bioink Growth. 3d打印支架模拟IBD肠道微环境:细菌生物链接生长的体外模型。
Alejandro Garcia-Gonzalez, Mariana Jaquez-Sanchez, Axel Maya-Morales, Mariana S Flores-Jimenez, Yocanxochitl Perfecto-Avalos, Isaac Chairez-Oria, Abel Gutierrez-Vilchis, Ricardo Garcia-Gamboa
{"title":"3D-Printed Scaffold Mimicking IBD Gut Microenvironments: An In Vitro Model for Bacterial Bioink Growth.","authors":"Alejandro Garcia-Gonzalez, Mariana Jaquez-Sanchez, Axel Maya-Morales, Mariana S Flores-Jimenez, Yocanxochitl Perfecto-Avalos, Isaac Chairez-Oria, Abel Gutierrez-Vilchis, Ricardo Garcia-Gamboa","doi":"10.1109/EMBC53108.2024.10782731","DOIUrl":"10.1109/EMBC53108.2024.10782731","url":null,"abstract":"<p><p>Inflammatory bowel disease (IBD), a chronic inflammatory condition of the gastrointestinal tract, affects millions worldwide and is linked to altered gut microbiota. This study explored the feasibility of a 3D-bioprinting scaffold containing Lactococcus lactis using an alginate-agar-soy trypticase bioink. The bioink exhibited high water absorption and adequate rheology, enabling successful bioprinting of scaffolds with robust structures. The scaffolds remained stable for 24 hours, allowing prolonged bacterial growth. L. lactis viability was confirmed by confocal microscopy, which revealed green fluorescence indicative of live bacteria even after 8 hours of culture within the scaffold. This suggests a supportive microenvironment for bacterial survival and potential proliferation. Compared to a 2D model, the 3D scaffold increased the number of colony-forming units (CFUs), indicating a more supportive environment for L. lactis growth. Overall, this study emphasizes the potential of 3D-printed bacterial scaffolds as a platform culture to assess the factors influencing the microbiota in various diseases.</p>","PeriodicalId":72237,"journal":{"name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","volume":"2024 ","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143559003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of Force Feedback Models in a Haptic Device Using Alignment Accuracy and Brain Activity. 利用对准精度和大脑活动评估触觉装置中的力反馈模型。
Harutake Nagai, Satoshi Miura
{"title":"Assessment of Force Feedback Models in a Haptic Device Using Alignment Accuracy and Brain Activity.","authors":"Harutake Nagai, Satoshi Miura","doi":"10.1109/EMBC53108.2024.10781934","DOIUrl":"10.1109/EMBC53108.2024.10781934","url":null,"abstract":"<p><p>When controlling a robot's velocity, it is necessary to provide force feedback to the user, which shows the amount of input from the neutral position. In this paper, we introduce three distinct force feedback models, each with one or two parameters, and investigate the influence on the operability of the robot and brain activity according to the changes of the force feedback model using a haptic device. Participants in the alignment task performed tasks in which they aligned an object with a target position in virtual space using our developed interface while we measured the participant's operational performance and brain activation using functional near-infrared spectroscopy. We performed fitting using quadratic functions with the parameters of each model as design variables. The results of the alignment task demonstrated that two models achieved higher alignment performance depending on the position of the target from the neutral position and, for one model, brain activation changed significantly as the parameters changed.</p>","PeriodicalId":72237,"journal":{"name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","volume":"2024 ","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143559080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deep Learning Method for Estimating Germ-layer Regions of Early Differentiated Human Induced Pluripotent Stem Cells on Micropattern Using Bright-field Microscopy Image. 基于明场显微图像的深度学习方法估计早期分化人诱导多能干细胞胚层区域
Slo-Li Chu, Hideo Yokota, Pai-Ting Wang, Kuniya Abe, Yohei Hayashi, Dooseon Cho, Ming-Dar Tsai
{"title":"Deep Learning Method for Estimating Germ-layer Regions of Early Differentiated Human Induced Pluripotent Stem Cells on Micropattern Using Bright-field Microscopy Image.","authors":"Slo-Li Chu, Hideo Yokota, Pai-Ting Wang, Kuniya Abe, Yohei Hayashi, Dooseon Cho, Ming-Dar Tsai","doi":"10.1109/EMBC53108.2024.10782655","DOIUrl":"10.1109/EMBC53108.2024.10782655","url":null,"abstract":"<p><p>Live cell staining is expensive and may bring potential safety issues in downstream clinical applications, bright-field images rather than staining images should be more suitable to reveal time-series changes of differentiating hiPSCs (human induced pluripotent stem cells) and three-germ layers differentiated from the hiPSCs. This study proposed a deep learning method for estimating immunofluorescence regions on a bright-field microscopy images. The networks trained by multiple types of fluorescence images can estimate the types of fluorescence images from a bright-field image. The estimated pseudo Hoechst image is used to segment hiPSCs, and the others classify the segmented hiPSCs as respective germ-layer cells. The experimental results show over 75% correct rates for the segmentation and classification were achieved, indicating the proposed method can be useful tool in evaluating pluripotency of hiPSC and delineating the germ layer formation process without cell staining.</p>","PeriodicalId":72237,"journal":{"name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","volume":"2024 ","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143559243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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