Vikram Krishna MD, Claire Perez MD, Drew Bolster MD, Kellie Knabe MSN, Raffaele Rocco MD, Philicia Moonsamy MD, MPH, Eugene S. Kim MD, Harmik J. Soukiasian MD, Andrew R. Brownlee MD
{"title":"Technical Considerations for Robotic Pediatric Lobectomy","authors":"Vikram Krishna MD, Claire Perez MD, Drew Bolster MD, Kellie Knabe MSN, Raffaele Rocco MD, Philicia Moonsamy MD, MPH, Eugene S. Kim MD, Harmik J. Soukiasian MD, Andrew R. Brownlee MD","doi":"10.1016/j.atssr.2026.03.003","DOIUrl":"10.1016/j.atssr.2026.03.003","url":null,"abstract":"<div><div>Robotic thoracic surgery in pediatric patients is technically challenging due to narrow anterior-posterior and lateral chest dimensions, which increases instrument collisions. Consequently, lung tumors in children are traditionally resected through a thoracotomy. We present a reproducible approach to robotic pediatric lobectomy in a 12-year-old girl with a biopsy specimen-proven left lower lobe mucoepidermoid carcinoma. Our technique uses 4 robotic ports, with 3 posterior ports in the ninth intercostal space and an anterior stapling port positioned 1 to 2 interspaces higher, achieving 6 to 8 cm of spacing. Preoperative marking and careful patient selection enable a feasible robotic lobectomy within the constrained pediatric thorax.</div></div><div>Robotic thoracic surgery in pediatric patients is technically challenging due to narrow anterior-posterior and lateral chest dimensions, which increases instrument collisions. Consequently, lung tumors in children are traditionally resected through a thoracotomy. We present a reproducible approach to robotic pediatric lobectomy in a 12-year-old girl with a biopsy specimen-proven left lower lobe mucoepidermoid carcinoma. Our technique uses 4 robotic ports, with 3 posterior ports in the ninth intercostal space and an anterior stapling port positioned 1 to 2 interspaces higher, achieving 6 to 8 cm of spacing. Preoperative marking and careful patient selection enable a feasible robotic lobectomy within the constrained pediatric thorax.</div>","PeriodicalId":72234,"journal":{"name":"Annals of thoracic surgery short reports","volume":"4 3","pages":"Pages 938-941"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148870984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Right Lung Torsion After Minimally Invasive Cardiac Surgery in a Child","authors":"Hiroki Kanamori MD, PhD, Akihiro Shimotakahara MD, PhD, Hirofumi Tomita MD, PhD, Yuya Komori MD, Kazuhiro Shoya MD, Satoshi Yazaki MD, Yukihiro Yoshimura MD, PhD","doi":"10.1016/j.atssr.2026.01.013","DOIUrl":"10.1016/j.atssr.2026.01.013","url":null,"abstract":"<div><div>Minimally invasive cardiac surgery (MICS) is becoming more common in pediatric congenital heart disease operation, yet its complications remain incompletely defined. We report a case of right upper and middle lobe torsion—a rare surgical complication—in a 4-year-old boy after MICS for ventricular septal defect. The torsion was discovered 1 week postoperatively while his respiratory and hemodynamic status remained relatively stable. Semiemergent resection of the twisted lobes was performed, and the patient recovered uneventfully. This case identifies lung torsion as a possible complication of MICS and illustrates the value of timely monitoring and intervention.</div></div><div>Minimally invasive cardiac surgery (MICS) is becoming more common in pediatric congenital heart disease operation, yet its complications remain incompletely defined. We report a case of right upper and middle lobe torsion—a rare surgical complication—in a 4-year-old boy after MICS for ventricular septal defect. The torsion was discovered 1 week postoperatively while his respiratory and hemodynamic status remained relatively stable. Semiemergent resection of the twisted lobes was performed, and the patient recovered uneventfully. This case identifies lung torsion as a possible complication of MICS and illustrates the value of timely monitoring and intervention.</div>","PeriodicalId":72234,"journal":{"name":"Annals of thoracic surgery short reports","volume":"4 3","pages":"Pages 945-947"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148870986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emma M. Federico BS, Alexander Pohlman MD, Madison Lozanoski PA-C, Zaid M. Abdelsattar MD, MS, Julia M. Coughlin MD
{"title":"Diagnostic Dilemmas and The Benefit of Robotic-Assisted Surgery in the Management of Neurogenic Thoracic Outlet Syndrome in Complex Patients","authors":"Emma M. Federico BS, Alexander Pohlman MD, Madison Lozanoski PA-C, Zaid M. Abdelsattar MD, MS, Julia M. Coughlin MD","doi":"10.1016/j.atssr.2026.01.001","DOIUrl":"10.1016/j.atssr.2026.01.001","url":null,"abstract":"<div><div>A 64-year-old male patient presented with progressive, debilitating bilateral arm pain for 2 years following traumatic cervical spine injuries requiring multiple operations. Despite extensive diagnostic workup by several specialists, he was left without a diagnosis, treatment plan, or ability to perform his job. He was diagnosed with bilateral neurogenic thoracic outlet syndrome, based on clinical diagnostic criteria. A 2-staged bilateral robotic first rib resection resulted in complete resolution of his symptoms.</div></div><div>A 64-year-old male patient presented with progressive, debilitating bilateral arm pain for 2 years following traumatic cervical spine injuries requiring multiple operations. Despite extensive diagnostic workup by several specialists, he was left without a diagnosis, treatment plan, or ability to perform his job. He was diagnosed with bilateral neurogenic thoracic outlet syndrome, based on clinical diagnostic criteria. A 2-staged bilateral robotic first rib resection resulted in complete resolution of his symptoms.</div>","PeriodicalId":72234,"journal":{"name":"Annals of thoracic surgery short reports","volume":"4 3","pages":"Pages 948-951"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148870995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Evelio Rodriguez MD, FACS, Milovan Petrovic MD, PhD, Krzysztof Milewski PhD n med, MBA, Slobodan Micovic MD, Andrej Preveden MD, PhD, Krzysztof Sanetra MD, PhD, Dragana Kosevic MD, Robert N. Sladen MBChB, FCCM
{"title":"Feasibility Study of Renal Negative Pressure Treatment After Cardiac Surgery With Cardiopulmonary Bypass","authors":"Evelio Rodriguez MD, FACS, Milovan Petrovic MD, PhD, Krzysztof Milewski PhD n med, MBA, Slobodan Micovic MD, Andrej Preveden MD, PhD, Krzysztof Sanetra MD, PhD, Dragana Kosevic MD, Robert N. Sladen MBChB, FCCM","doi":"10.1016/j.atssr.2026.01.017","DOIUrl":"10.1016/j.atssr.2026.01.017","url":null,"abstract":"<div><h3>Background</h3><div>We conducted a technical feasibility and safety study of intraureteric renal negative pressure treatment (rNPT) in patients with chronic kidney disease undergoing elective cardiac surgery with cardiopulmonary bypass</div></div><div><h3>Methods</h3><div>After written informed consent, 10 patients with preoperative estimated glomerular filtration rate of 15 to 59 mL/min per 1.73 m<sup>2</sup> were enrolled at 3 sites. At the end of surgery, a urologist advanced a specialized ureteral catheter into each renal pelvis under radiographic guidance. Intra.renal negative pressure of −15 mm Hg was initiated postoperatively and continued for 24 hours. Patients were followed up on postoperative days 14 and 28.</div></div><div><h3>Results</h3><div>Three patients had major protocol deviations with primary catheter misplacement; acute kidney injury developed in 1 of these. Bilateral renal pelvis catheters were deployed per protocol in 7 patients. All patients had microhematuria; 2 had transient hematuria. In the per-protocol group, acute kidney injury developed in 1 patient with stage 4 chronic kidney disease. No patient suffered any other major adverse event. Serum creatinine concentration remained normal in 6 patients at 72 hours; and in 5 patients, estimated glomerular filtration rate had improved from baseline at 28 days.</div></div><div><h3>Conclusions</h3><div>rNPT is feasible after cardiac surgery. If catheter placement protocol is strictly followed, it is associated with minimal patient risk and potential benefit. A controlled study (NCT07017933) is in progress to evaluate rNPT started before cardiopulmonary bypass and continued postoperatively.</div></div><div><h3>ClinicalTrials.gov identifier</h3><div>NCT05990660</div></div>","PeriodicalId":72234,"journal":{"name":"Annals of thoracic surgery short reports","volume":"4 3","pages":"Pages 1047-1052"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148870540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adrian Valderrama MD, Andrea Michelle Gochi MD, Amanda Soe BA, Elaine Liang BA, Alison Baskin MD, Jeffrey B. Velotta MD, FACS
{"title":"Assessing the Evidence Behind Guidelines in Cardiothoracic Surgery: A Systematic Review","authors":"Adrian Valderrama MD, Andrea Michelle Gochi MD, Amanda Soe BA, Elaine Liang BA, Alison Baskin MD, Jeffrey B. Velotta MD, FACS","doi":"10.1016/j.atssr.2026.01.018","DOIUrl":"10.1016/j.atssr.2026.01.018","url":null,"abstract":"<div><h3>Background</h3><div>Clinical practice guidelines are essential for guiding clinical decisions in cardiothoracic surgery. Despite this, the quality of evidence supporting cardiothoracic surgery guidelines has not been formally assessed. This systematic review characterizes the level of evidence underlying current cardiothoracic surgery guidelines.</div></div><div><h3>Methods</h3><div>We extracted recommendations from US professional society guidelines that addressed cardiac or thoracic surgery and used the American College of Cardiology evidence framework. Recommendations were characterized by their level of evidence and assigned a phase of care by 2 independent raters. The primary outcome was the level of evidence across all guidelines, stratified by recommendation strength, phase of care, and disease process.</div></div><div><h3>Results</h3><div>We identified 2 professional societies, American Association for Thoracic Surgery and The Society of Thoracic Surgeons, that published 24 guidelines meeting inclusion criteria. These contained 714 eligible recommendations; 52 (7%) had level A evidence, indicating support from multiple randomized controlled trials or 1 large randomized controlled trial. Of the recommendations classified as strong, 33 (10%) had level A evidence. Perioperative recommendations had the highest proportion of level A support (14%) compared with intraoperative (7%) and nonoperative (1%) recommendations. By disease process, level A evidence ranged from 44% in esophageal guidelines to 0% in coronary artery disease, aorta, and congenital heart disease guidelines.</div></div><div><h3>Conclusions</h3><div>Few clinical practice guidelines in cardiothoracic surgery are supported by high-quality evidence. This highlights a significant evidence gap and the need to strengthen the rigor of evidence generation, particularly for surgical interventions.</div></div>","PeriodicalId":72234,"journal":{"name":"Annals of thoracic surgery short reports","volume":"4 3","pages":"Pages 1081-1086"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148870543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ana María Picó BA, Aabha Divya MD, Asishana A. Osho MD, Motahar Hosseini MD, Jordan P. Bloom MD, Serguei Melnitchouk MD, Arminder S. Jassar MD, Thoralf M. Sundt MD, Antonia Kreso MD, PhD
{"title":"Presentation and Outcomes of Women and Men After Elective Proximal Aortic Surgery: Retrospective Institutional Analysis","authors":"Ana María Picó BA, Aabha Divya MD, Asishana A. Osho MD, Motahar Hosseini MD, Jordan P. Bloom MD, Serguei Melnitchouk MD, Arminder S. Jassar MD, Thoralf M. Sundt MD, Antonia Kreso MD, PhD","doi":"10.1016/j.atssr.2026.01.004","DOIUrl":"10.1016/j.atssr.2026.01.004","url":null,"abstract":"<div><h3>Background</h3><div>An increasing number of studies are demonstrating how outcomes in women are different from those in men after cardiac surgery. Current research lacks data on the outcomes in elective proximal aortic surgery.</div></div><div><h3>Methods</h3><div>We retrospectively reviewed 1299 patients undergoing elective aortic surgery between 2010 and 2023; 347 (27.7%) were women. We examined preoperative and postoperative characteristics and analyzed the data with respect to morbidity and mortality in men compared with women.</div></div><div><h3>Results</h3><div>Demographic data of these cases showed that women had lower body mass index (27.4 kg/m<sup>2</sup> vs 28.7 kg/m<sup>2</sup>; <em>P</em> = .001) and creatinine level (0.882 vs 1.03 mg/dL; <em>P</em> < .001), less hypertension (64.8% vs 74.2%; <em>P</em> = .001), and more chronic obstructive pulmonary disease (8.6% vs 5.1%; <em>P</em> = .028) but similar prevalence of diabetes and smoking. Despite that men had greater procedure length (336 minutes vs 313 minutes; <em>P</em> = .003) and cross-clamp time (134 minutes vs 120 minutes; <em>P</em> < .001), women spent more time in the intensive care unit (83.4 hours vs 55.9 hours; <em>P</em> = .009) and on the ventilator (40.7 hours vs 18.2 hours; <em>P</em> = .021), experienced more postoperative complications (54.8% vs 46.2%; <em>P</em> = .007), and had longer stays (9.73 days vs 7.97 days; <em>P</em> = .002). In-hospital mortality was similar.</div></div><div><h3>Conclusions</h3><div>These results emphasize the need for sex-specific strategies in aortic surgery and further work on identifying the factors that differ between men and women that result in variable outcomes after elective aortic surgery.</div></div>","PeriodicalId":72234,"journal":{"name":"Annals of thoracic surgery short reports","volume":"4 3","pages":"Pages 747-751"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148870546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Comanici MD, Abu Ali Farmidi FRCS(CTh), Sunil K. Bhudia FRCS(CTh), Nandor Marczin PhD, Shahzad G. Raja FRCS(CTh)
{"title":"Incidence and Determinants of Repeat Revascularization After Off- and On-Pump Multivessel Coronary Surgery","authors":"Maria Comanici MD, Abu Ali Farmidi FRCS(CTh), Sunil K. Bhudia FRCS(CTh), Nandor Marczin PhD, Shahzad G. Raja FRCS(CTh)","doi":"10.1016/j.atssr.2026.01.010","DOIUrl":"10.1016/j.atssr.2026.01.010","url":null,"abstract":"<div><h3>Background</h3><div>Coronary artery bypass grafting is an established treatment for multivessel coronary artery disease. However, the occurrence of repeat revascularization over extended follow-up remains clinically relevant. This study aimed to determine the long-term incidence and predictors of repeat revascularization after off-pump and on-pump multivessel coronary artery bypass grafting.</div></div><div><h3>Methods</h3><div>A retrospective cohort of 10,360 patients who underwent multivessel coronary artery bypass grafting between 1996 and 2017 was analyzed. Propensity score matching (1:1, caliper 0.1) was applied to preoperative variables, yielding 4421 matched pairs. Covariate balance was confirmed using standardized mean differences. Repeat revascularization was defined as any postindex percutaneous coronary intervention or redo coronary artery bypass grafting. Survival free from reintervention was evaluated using Kaplan-Meier analysis. Cox proportional hazards models identified factors associated with repeat revascularization.</div></div><div><h3>Results</h3><div>Freedom from repeat revascularization at 20 years was comparable between matched off-pump and on-pump groups (93.2% vs 90.3%; <em>P</em> = .866). Overall, 249 patients (2.8%) underwent repeat revascularization, predominantly percutaneous coronary intervention. Increasing age and double-vessel coronary artery disease were protective, while prior percutaneous coronary intervention more than 24 hours before surgery was associated with increased risk. Surgical technique (on-pump or off-pump) was not an independent predictor.</div></div><div><h3>Conclusions</h3><div>Long-term freedom from repeat revascularization after multivessel coronary artery bypass grafting is high and comparable between off-pump and on-pump coronary artery bypass grafting. Older age and less extensive coronary disease were protective, while prior percutaneous coronary intervention conferred increased risk. These findings may guide preoperative risk stratification and long-term management planning.</div></div>","PeriodicalId":72234,"journal":{"name":"Annals of thoracic surgery short reports","volume":"4 3","pages":"Pages 788-792"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148870772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brian Bateson DO, Brittany Ange EdD, MS, Bhargav Doddala MPH, Emma Hazenberg BS, MPH, Lyubomyr Bohuta MD, PhD, James St. Louis MD
{"title":"Use and Outcomes Associated With a Clear Prime for Infants Undergoing Cardiac Surgery","authors":"Brian Bateson DO, Brittany Ange EdD, MS, Bhargav Doddala MPH, Emma Hazenberg BS, MPH, Lyubomyr Bohuta MD, PhD, James St. Louis MD","doi":"10.1016/j.atssr.2026.02.024","DOIUrl":"10.1016/j.atssr.2026.02.024","url":null,"abstract":"<div><h3>Background</h3><div>The benefits of restricting blood transfusion at the time of cardiac surgery have been shown previously. Given the paucity of information in the pediatric population, we compared outcomes and use of a clear vs a blood prime.</div></div><div><h3>Methods</h3><div>The Society of Thoracic Surgeons Congenital Heart Surgery Database was used to evaluate patients (2.5-12 kg) undergoing an index operation between January 1, 2016, and June 30, 2022 (versions 3.3 and 3.41). Demographics, intraoperative variables, and outcomes were investigated. Categorical variables were analyzed with χ<sup>2</sup> tests, and Mann-Whitney <em>U</em> tests were calculated for continuous variables. Statistical significance was set at <em>P</em> < .0571.</div></div><div><h3>Results</h3><div>During the study period, there were 60,037 patients with a blood prime and 7875 patients with a clear prime. The clear prime cohort was larger (weight, 7.3 kg vs 5.8 kg; body surface area, 0.4 m<sup>2</sup> vs 0.3 m<sup>2</sup>) and older (380.2 days vs 198.0 days; all <em>P</em> < .0001. The blood prime group had more chromosomal abnormalities, nonchromosomal anatomic abnormalities, and any preoperative factor (all <em>P</em> < .0001). The clear prime cohort had a lower hematocrit, shorter time on a ventilator, shorter length of stay, and decreased complications (all <em>P</em> < .0001).</div></div><div><h3>Conclusions</h3><div>Clear prime use has increased and was associated with a shorter time ventilated, extubation in the operating room, and decreased length of stay. Further studies are needed to identify opportunities to enhance blood conservation.</div></div>","PeriodicalId":72234,"journal":{"name":"Annals of thoracic surgery short reports","volume":"4 3","pages":"Pages 863-867"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148870939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ioana B. Florea MD, MPHS, Sajjad Sabir MD, Jeffrey Lee DO, Sarah Van Dyke PA-C, Gary Cook PA-C, Michael Rosenbloom MD, David D. Shersher MD, Kenji Minakata MD, PhD
{"title":"Cardiac Sarcoma: A Rare Etiology of Outflow Tract Obstruction","authors":"Ioana B. Florea MD, MPHS, Sajjad Sabir MD, Jeffrey Lee DO, Sarah Van Dyke PA-C, Gary Cook PA-C, Michael Rosenbloom MD, David D. Shersher MD, Kenji Minakata MD, PhD","doi":"10.1016/j.atssr.2026.03.018","DOIUrl":"10.1016/j.atssr.2026.03.018","url":null,"abstract":"<div><div>Cardiac sarcomas are exceedingly rare clinical entities that can require expeditious surgical intervention for relief of symptomatic and hemodynamic sequelae and for improved oncologic outcomes. Here we present 2 cases of primary sarcoma resulting in markedly symptomatic obstruction of the left and right ventricular outflow tracts, thus highlighting the principles of surgical intervention for these rare malignant lesions.</div></div><div>Cardiac sarcomas are exceedingly rare clinical entities that can require expeditious surgical intervention for relief of symptomatic and hemodynamic sequelae and for improved oncologic outcomes. Here we present 2 cases of primary sarcoma resulting in markedly symptomatic obstruction of the left and right ventricular outflow tracts, thus highlighting the principles of surgical intervention for these rare malignant lesions.</div>","PeriodicalId":72234,"journal":{"name":"Annals of thoracic surgery short reports","volume":"4 3","pages":"Pages 845-848"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148870884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eetu Haavisto MSc, Henri Haapanen MD, PhD, Liisa Petäjä MD, PhD, Peter Raivio MD, PhD, Esko Kankuri MD, PhD, Mikko Jormalainen MD, PhD, Kalle Kotilahti DSc, Tatu Juvonen MD, PhD, Tommi Pätilä MD, PhD
{"title":"Real-time Myocardial Oximetry—Preclinical Monitoring Device Validation in a Porcine Beating-Heart Cardiopulmonary Bypass Model","authors":"Eetu Haavisto MSc, Henri Haapanen MD, PhD, Liisa Petäjä MD, PhD, Peter Raivio MD, PhD, Esko Kankuri MD, PhD, Mikko Jormalainen MD, PhD, Kalle Kotilahti DSc, Tatu Juvonen MD, PhD, Tommi Pätilä MD, PhD","doi":"10.1016/j.atssr.2026.01.015","DOIUrl":"10.1016/j.atssr.2026.01.015","url":null,"abstract":"<div><h3>Purpose</h3><div>Continuous, real-time monitoring of myocardial oxygenation during cardiac surgery holds potential for enhancing patient safety and improving outcomes. This study evaluated the precision of the near-infrared spectroscopy-based SpectroCor Ltd monitoring device, which measures myocardial hemoglobin/myoglobin (Hb/Mb) oxygen saturation and cytochrome c oxidase (CcO) oxidation ratio.</div></div><div><h3>Description</h3><div>Yorkshire pigs, under general anesthesia, were subjected to cardiopulmonary bypass to generate graded myocardial desaturation. Graded desaturation at aortic root was induced by mixing oxygenated blood from partly pumping cardiopulmonary bypass with deoxygenated blood passing nonventilated lungs. SpectroCor myocardial oximetry was validated against blood samples drawn simultaneously from the aortic root and coronary sinus during various stable saturation intervals.</div></div><div><h3>Evaluation</h3><div>With accuracy of 5.3 percentage points, the SpectroCor device’s myocardial Hb/Mb oxygen saturation readings tightly correlated with reference blood samples. Concurrent changes in CcO oxidation ratio closely mirrored Hb/Mb saturation, indicating reliable assessment of mitochondrial function.</div></div><div><h3>Conclusions</h3><div>The SpectroCor monitoring device provides accurate, real-time measurements of myocardial oxygenation, supporting its potential to help optimize cardioprotective strategies during cardiac surgery.</div></div>","PeriodicalId":72234,"journal":{"name":"Annals of thoracic surgery short reports","volume":"4 3","pages":"Pages 1058-1065"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148871008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}