{"title":"JSNC 2020 in Aichi","authors":"J. Hashimoto","doi":"10.17996/anc.19-002","DOIUrl":"https://doi.org/10.17996/anc.19-002","url":null,"abstract":"","PeriodicalId":72228,"journal":{"name":"Annals of nuclear cardiology","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85879348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"82Rb is the Best Flow Tracer for High-volume Sites","authors":"R. Klein, R. deKemp","doi":"10.17996/anc.19-00105","DOIUrl":"https://doi.org/10.17996/anc.19-00105","url":null,"abstract":"Rubidium-82 is the most well-established cardiac PET flow tracer with over 6 decades of literature. Due to its robust supply, short physical half-life, ease of use, low radiation dose and favorable kinetics it can deliver comprehensive clinical information with minimal risk and maximum convenience to patients and clinical staff. Optimized 82 Rb protocols can deliver high quality myocardial perfusion imaging, functional cardiac images and absolute myocardial blood flow and flow reserve from a single session 30 minutes clinical protocol‒benefiting patient convenience and clinical throughput. In a high volume setting the cost of 82 Rb PET can be dramatically lower than that of alternative PET flow tracers. These factors compound toward 82 Rb as the best PET flow tracer for high-throughput clinics.","PeriodicalId":72228,"journal":{"name":"Annals of nuclear cardiology","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76015160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Application of Quantitative Myocardial Blood Flow Accessment Using Positron Emission Tomography","authors":"Ping Wu, Sijin Li, Xiaoshan Guo, Ruonan Wang","doi":"10.17996/ANC.19-00091","DOIUrl":"https://doi.org/10.17996/ANC.19-00091","url":null,"abstract":"Epicardial coronary artery disease has been highly noticed in the traditional clinical examination, while myocardial microcirculation function has been neglected for a long time, which plays a nonnegligible role in quite a few patients’ clinical manifestations and prognosis. Non-invasive quantitative PET myocardial perfusion imaging has become a unique and gold standard of evaluating myocardial microcirculation function. Its clinical applications in diagnosis, risk stratification, prognosis evaluation, efficacy evaluation and treatment guidance of cardiovascular diseases are given, together with its development status in China.","PeriodicalId":72228,"journal":{"name":"Annals of nuclear cardiology","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81191041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Muramatsu, S. Nishimura, Y. Takeishi, T. Nishimura
{"title":"Prognostic Risk Stratification of Cardiac Events Evaluated by Aortic Calcification in Elderly Patients with Chronic Kidney Disease","authors":"T. Muramatsu, S. Nishimura, Y. Takeishi, T. Nishimura","doi":"10.17996/ANC.19-00090","DOIUrl":"https://doi.org/10.17996/ANC.19-00090","url":null,"abstract":"Background : The relationship between myocardial perfusion imaging (MPI) and aortic calcification (AoC) in chronic kidney disease (CKD) patients remains unclear. Methods : The Japanese Assessment of Cardiac Events and Survival Study by quantitative gated single-photon emission computed tomography (J-ACCESS 3) is a multicenter, prospective cohort study investigating the ability of MPI to predict cardiac events in 529 CKD patients. In J-ACCESS 3, the sum of myocardial perfusion defect score at stress (SSS) was a useful predictor of cardiac major events in CKD patients. However, aortic calcification was not examined. We examined the prognosis of patients with CKD according to the presence or absence of AoC using data from the J-ACCESS 3 cohort. Results : There were 60 major cardiac events (three cardiac deaths, six sudden deaths, five non-fatal myocardial infarctions, 46 hospitalization cases for heart failure). In the univariate analysis, patients with AoC had a higher left ventricular (LV) ejection fraction, smaller LV volume, and lower SSS by MPI. Kaplan ‒ Meier curves showed a significantly higher incidence of major cardiac events in the AoC group (P = 0.0041). Patients were categorized into the following four groups: Group A (non-AoC and SSS < 4; normal score of 0 ‒ 3); Group B (AoC and SSS < 4); Group C (non-AoC and SSS ≧ 4); Group D (AoC and SSS ≧ 4). Kaplan ‒ Meier curves showed that the major cardiac events rates were A < B < C < D (P = 0.002). The difference was most pronounced between the AoC and no-AoC groups with SSS < 4. Conclusions : The combination of SSS using MPI and AoC is a useful predictor of cardiac major events in CKD patients.","PeriodicalId":72228,"journal":{"name":"Annals of nuclear cardiology","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74795571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Worldwide Availability and Utilization of PET/CT from IAEA Survey","authors":"J. Vitola, M. Dondi, P. Prado, L. Shaw, D. Paez","doi":"10.17996/anc.19-00103","DOIUrl":"https://doi.org/10.17996/anc.19-00103","url":null,"abstract":"Hybrid imaging using PET/CT have various applications in cardiology. Anatomy, physiology or both can be evaluated. Routine attenuation correction can be performed and improve accuracy for nuclear cardiology studies. The extent of availability and utilization of hybrid imaging technology worldwide is currently unknown. The International Atomic Energy Agency (IAEA) in cooperation with QUANTA performed a web-based survey among physicians working with nuclear imaging to evaluate the current availability of hybrid imaging and its use for nuclear cardiology (NC). Contact e mails of physicians working in the field of nuclear cardiology were available from a data base at the human health department of the IAEA in Vienna, Austria and an international network of nuclear cardiologist at QUANTA in Curitiba, Brazil. Data from 80 countries in both high-income countries (HIC, n = 16) and low-and-middle income countries (LMIC, n = 64) representing all world regions, was obtained. At the country level, PET/CT is available in all world regions being widely available in North and Latin America, Europe, Asia and Oceania with a heterogeneous availability in Africa. Nevertheless, only 22.4% of centers in HIC and 10.9% in LMIC that have PET/CT available use it for NC applications. These data will help us to work with scientific societies and institutions to design strategies to diffuse information for physicians so they can take full advantage of PET/CT technology to obtain additional information that could impact patient care.","PeriodicalId":72228,"journal":{"name":"Annals of nuclear cardiology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80005391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Increasing the Presence of ANC among Academia","authors":"K. Yoshinaga","doi":"10.17996/anc.19-00108","DOIUrl":"https://doi.org/10.17996/anc.19-00108","url":null,"abstract":"L ast weekend, the Japanese Society of Nuclear Cardiology (JSNC) conducted its 29 th annual scientific meeting in Hakodate on Hokkaido island. Dr. Tomoaki Nakata put great effort into preparations for this meeting. Dr. Nakata’s scientific program attracted many JSNC members to join the annual scientific meeting, and participation was estimated to be at a record high. From an academic research point of view, the highlights of this scientific gathering were the young investigator award session (YIA) and the technologist awards sessions. According to the scientific committee, a total of 14 abstracts were submitted to YIA and a total of 26 abstracts were submitted to the technologist sessions. Five finalists in the technological sessions had especially strong and sophisticated presentations showing important technical approaches with great potential to contribute to daily clinical practice. One of the aims of JSNC includes promoting technical and clinical aspects of research in nuclear cardiology. In this regard, the technologist award sessions should be considered one of the greatest achievements of JSNC. The JSNC annual scientific meeting also had record high numbers of scientific abstract presentations, and attendees participated in intensive discussions at each presentation. Presentation of an abstract is important but is only part of the overall process of accomplishing a research project. As editor-in-chief of the Annals of Nuclear Cardiology (ANC), I strongly hope that those who presented their abstract will publish their research in our journal, ANC.","PeriodicalId":72228,"journal":{"name":"Annals of nuclear cardiology","volume":"2014 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86803563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Survey Research","authors":"David N. Williams, K. Williams","doi":"10.17996/anc.19-00102","DOIUrl":"https://doi.org/10.17996/anc.19-00102","url":null,"abstract":"Survey research studies are frequently done badly, resulting in unreliable data. Response rates for clinical research are commonly below 30%, far less than considered reasonable for accuracy or validity. Addressing 10 weak points common to many studies would help to improve the quality of outcomes. Careful attention to the data needed to meet the research objective, clearly defined population definition, frame, sample and implementation planning all build a foundation for rigorous research. The survey delivery method(s), questionnaire design, write-up, pre-test of the questionnaire and mixed method, multiple follow-ups all should all work toward maximizing response rates. Well cleaned data will deliver high quality final results.","PeriodicalId":72228,"journal":{"name":"Annals of nuclear cardiology","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86023255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Toyama, H. Hoshizaki, S. Kasama, Yusuke Miyaishi, Hakuken Kan, E. Yamashita, R. Kawaguchi, S. Oshima, M. Kurabayashi
{"title":"Usefulness of Hyper Early Granulocyte-colony-stimulating Factor Therapy for Patients with Acute Myocardial Infarction","authors":"T. Toyama, H. Hoshizaki, S. Kasama, Yusuke Miyaishi, Hakuken Kan, E. Yamashita, R. Kawaguchi, S. Oshima, M. Kurabayashi","doi":"10.17996/anc.19-00099","DOIUrl":"https://doi.org/10.17996/anc.19-00099","url":null,"abstract":"Objective: It has been reported that granulocyte-colony-stimulating-factor (G-CSF) induces myocardial regeneration and revascularization after acute myocardial infarction (AMI) by mobilizing bone marrow stem cells and suppressing apoptosis of endothelial cells in the injured heart. This study investigated whether hyper early G-CSF therapy was beneficial for AMI patients. Methods: Forty consecutive patients with initial ST-segment elevation AMI were randomized to receive intravenous infusion of G-CSF at 2μg/kg over 30 min (G-CSF group) or infusion of normal saline (control group) once daily for 5 days. The first dose was administered during primary percutaneous coronary intervention just after hospitalization. In the subacute period and 6 months after AMI, all patients underwent myocardial scintigraphy, including 99m Tc-sestamibi imaging of myocardial perfusion and 123 I-beta-methyl-piodophenylpentadecanoic-acid ( 123 I-BMIPP) imaging to assess fatty acid metabolism. Results: The two groups had a similar myocardial area at risk, as evaluated by the extent score on subacute 123 IBMIPP imaging. Compared with the control group, the G-CSF group had a significantly smaller (p<0.05) total defect score on 99m Tc-sestamibi and 123 I-BMIPP imaging at 6 months. In addition, the left ventricular ejection fraction and regional wall motion score were larger in the G-CSF group than in the control group during the subacute period and after 6 months. Conclusions: Hyper early G-CSF therapy improves myocardial perfusion, fatty acid metabolism, and cardiac function after AMI.","PeriodicalId":72228,"journal":{"name":"Annals of nuclear cardiology","volume":"77 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72524336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From Myocardial Blood Flow to Receptor Imaging with PET","authors":"T. Schindler","doi":"10.17996/ANC.19-00094","DOIUrl":"https://doi.org/10.17996/ANC.19-00094","url":null,"abstract":"","PeriodicalId":72228,"journal":{"name":"Annals of nuclear cardiology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90981002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Quantitative Assessment of Lower-limb Perfusion for Patients with Peripheral Artery Disease","authors":"Y. Fukushima, S. Kumita","doi":"10.17996/ANC.19-00089","DOIUrl":"https://doi.org/10.17996/ANC.19-00089","url":null,"abstract":"Diagnostic procedures of noninvasive assessment for patients with peripheral artery disease (PAD) have been advancing for decades. Among diagnostic imaging modalities, lower-limb perfusion (LLP) planar scintigraphy and SPECT/CT are exclusively used for diagnosing lower-limb ischemia, therapeutic efficacies, and risk stratification in PAD patients. Of these modalities, LLP SPECT/CT particularly shows more accuracy in providing quantitative assessment of LLP using innovative imaging devices and dedicated software. dividing","PeriodicalId":72228,"journal":{"name":"Annals of nuclear cardiology","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80517828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}