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Androgens: clinical research and therapeutics最新文献

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Recognizing the True Value of Testosterone Therapy in Health Care. 认识到睾酮疗法在医疗保健中的真正价值。
Androgens: clinical research and therapeutics Pub Date : 2022-12-28 eCollection Date: 2022-01-01 DOI: 10.1089/andro.2022.0021
Abraham Morgentaler, Abdulmaged Traish, Rajat S Barua, Paresh Dandona, Sandeep Dhindsa, Mohit Khera, Farid Saad
{"title":"Recognizing the True Value of Testosterone Therapy in Health Care.","authors":"Abraham Morgentaler, Abdulmaged Traish, Rajat S Barua, Paresh Dandona, Sandeep Dhindsa, Mohit Khera, Farid Saad","doi":"10.1089/andro.2022.0021","DOIUrl":"10.1089/andro.2022.0021","url":null,"abstract":"<p><p>There has been little recognition within the medical community of the health impact of testosterone (T) deficiency (TD), also known as hypogonadism, and the substantial benefits of testosterone therapy (TTh) on health and quality of life despite high-level clinical evidence. In a roundtable symposium, investigators summarized the contemporary evidence in several key clinical areas. TD negatively impacts human health and quality of life and is associated with increased mortality. Several studies have demonstrated that TTh in men with TD reduced all-cause and cardiovascular mortality. The longstanding belief that TTh is associated with increased prostate cancer (PCa) risk is contradicted by recent evidence, including multiple studies showing that TTh is associated with reduced PCa risk. Similarly, the weight of current evidence indicates the purported concern that TTh is associated with increased cardiovascular risk is incorrect. Normalization of physiological T reduces myocardial infarction, stroke, and deaths compared with men whose testosterone levels failed to normalize. In diabetic men TTh improves insulin resistance, and a large 2-year controlled study in men with abnormal glucose tolerance showed a substantially reduced rate of diabetes among men treated with TTh compared with untreated controls. Long-term TTh in diabetic men resulted in progressive improvements in obesity and insulin requirements, including a substantial number who experienced complete remission of diabetes. Finally, TTh has been shown to reduce severe outcomes with Covid-19 infection. These lines of evidence argue strongly for the need for greater awareness in the medical community of the impact of TD on health, and of the health benefits of TTh.</p>","PeriodicalId":72197,"journal":{"name":"Androgens: clinical research and therapeutics","volume":"3 1","pages":"217-223"},"PeriodicalIF":0.0,"publicationDate":"2022-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814113/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10527350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Potential Protective Effects of Testosterone Therapy on Prostate Cancer 睾酮治疗对前列腺癌的潜在保护作用
Androgens: clinical research and therapeutics Pub Date : 2022-12-01 DOI: 10.1089/andro.2022.0012
A. Johny, Pratik Kanabur, M. Khera
{"title":"Potential Protective Effects of Testosterone Therapy on Prostate Cancer","authors":"A. Johny, Pratik Kanabur, M. Khera","doi":"10.1089/andro.2022.0012","DOIUrl":"https://doi.org/10.1089/andro.2022.0012","url":null,"abstract":"","PeriodicalId":72197,"journal":{"name":"Androgens: clinical research and therapeutics","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83799074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Oral Testosterone Undecanoate (Kyzatrex) Versus Testosterone Gel (Androgel) on Long-Term (to 12 Months) Blood Pressure Levels 口服十一酸睾酮(Kyzatrex)与睾酮凝胶(Androgel)对长期(12个月)血压水平的影响
Androgens: clinical research and therapeutics Pub Date : 2022-12-01 DOI: 10.1089/andro.2022.0011
W. White, James Bernstein, A. Morgentaler, Om Dhingra
{"title":"Effects of Oral Testosterone Undecanoate (Kyzatrex) Versus Testosterone Gel (Androgel) on Long-Term (to 12 Months) Blood Pressure Levels","authors":"W. White, James Bernstein, A. Morgentaler, Om Dhingra","doi":"10.1089/andro.2022.0011","DOIUrl":"https://doi.org/10.1089/andro.2022.0011","url":null,"abstract":"","PeriodicalId":72197,"journal":{"name":"Androgens: clinical research and therapeutics","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80017775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Evolving Role of Novel Oral Agents for Testosterone Replacement Therapy; A Historical Perspective 新型口服药物在睾酮替代治疗中的作用历史的视角
Androgens: clinical research and therapeutics Pub Date : 2022-12-01 DOI: 10.1089/andro.2021.0025
Pratik Kanabur, R. Brunner, Dalia Khera, Hunter Flores, M. Khera
{"title":"The Evolving Role of Novel Oral Agents for Testosterone Replacement Therapy; A Historical Perspective","authors":"Pratik Kanabur, R. Brunner, Dalia Khera, Hunter Flores, M. Khera","doi":"10.1089/andro.2021.0025","DOIUrl":"https://doi.org/10.1089/andro.2021.0025","url":null,"abstract":"","PeriodicalId":72197,"journal":{"name":"Androgens: clinical research and therapeutics","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76461810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Androgens and Hepatic Adenomas: A Review from a Urological Perspective 雄激素与肝腺瘤:从泌尿外科角度的综述
Androgens: clinical research and therapeutics Pub Date : 2022-12-01 DOI: 10.1089/andro.2022.0008
E. Huang, M. Divatia, M. Villarreal, B. Miles
{"title":"Androgens and Hepatic Adenomas: A Review from a Urological Perspective","authors":"E. Huang, M. Divatia, M. Villarreal, B. Miles","doi":"10.1089/andro.2022.0008","DOIUrl":"https://doi.org/10.1089/andro.2022.0008","url":null,"abstract":"","PeriodicalId":72197,"journal":{"name":"Androgens: clinical research and therapeutics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84557331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Testosterone Therapy in Men on Active Surveillance 积极监测男性的睾酮治疗
Androgens: clinical research and therapeutics Pub Date : 2022-12-01 DOI: 10.1089/andro.2022.0004
Tristan Chun, Jacob Tannenbaum, H. Watts, I. Voznesensky, W. Almajed, W. Hellstrom
{"title":"Testosterone Therapy in Men on Active Surveillance","authors":"Tristan Chun, Jacob Tannenbaum, H. Watts, I. Voznesensky, W. Almajed, W. Hellstrom","doi":"10.1089/andro.2022.0004","DOIUrl":"https://doi.org/10.1089/andro.2022.0004","url":null,"abstract":"","PeriodicalId":72197,"journal":{"name":"Androgens: clinical research and therapeutics","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83682332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Approach to Testosterone Therapy in Men After Treatment for Localized Prostate Cancer 男性局限性前列腺癌治疗后睾酮治疗的探讨
Androgens: clinical research and therapeutics Pub Date : 2022-12-01 DOI: 10.1089/andro.2021.0031
Aubrey Reeves, D. Barham, F. Yafi
{"title":"An Approach to Testosterone Therapy in Men After Treatment for Localized Prostate Cancer","authors":"Aubrey Reeves, D. Barham, F. Yafi","doi":"10.1089/andro.2021.0031","DOIUrl":"https://doi.org/10.1089/andro.2021.0031","url":null,"abstract":"","PeriodicalId":72197,"journal":{"name":"Androgens: clinical research and therapeutics","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80643584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bias Among Health Care Professionals: How Prejudice Leads to Diagnostic Delay in Patients Using Anabolic–Androgenic Steroids 医疗保健专业人员的偏见:偏见如何导致使用合成代谢-雄激素类固醇患者的诊断延迟
Androgens: clinical research and therapeutics Pub Date : 2022-12-01 DOI: 10.1089/andro.2022.0016
Maria J. Rops, D. L. Smit, W. de Ronde
{"title":"Bias Among Health Care Professionals: How Prejudice Leads to Diagnostic Delay in Patients Using Anabolic–Androgenic Steroids","authors":"Maria J. Rops, D. L. Smit, W. de Ronde","doi":"10.1089/andro.2022.0016","DOIUrl":"https://doi.org/10.1089/andro.2022.0016","url":null,"abstract":"","PeriodicalId":72197,"journal":{"name":"Androgens: clinical research and therapeutics","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78153063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The Role of Post-Radical Prostatectomy Testosterone Therapy in Erectile Function Recovery 根治性前列腺切除术后睾酮治疗在勃起功能恢复中的作用
Androgens: clinical research and therapeutics Pub Date : 2022-10-01 DOI: 10.1089/andro.2022.0005
L. Huynh, R. Gevorkyan, T. Ahlering
{"title":"The Role of Post-Radical Prostatectomy Testosterone Therapy in Erectile Function Recovery","authors":"L. Huynh, R. Gevorkyan, T. Ahlering","doi":"10.1089/andro.2022.0005","DOIUrl":"https://doi.org/10.1089/andro.2022.0005","url":null,"abstract":"","PeriodicalId":72197,"journal":{"name":"Androgens: clinical research and therapeutics","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77875696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Premature Ejaculation and Its Association with Serum Testosterone Levels: A Comprehensive Review 早泄及其与血清睾酮水平的关系:一个全面的综述
Androgens: clinical research and therapeutics Pub Date : 2022-10-01 DOI: 10.1089/andro.2021.0026
Robert H. Drury, J. Greenberg, M. Lerner, W. Hellstrom
{"title":"Premature Ejaculation and Its Association with Serum Testosterone Levels: A Comprehensive Review","authors":"Robert H. Drury, J. Greenberg, M. Lerner, W. Hellstrom","doi":"10.1089/andro.2021.0026","DOIUrl":"https://doi.org/10.1089/andro.2021.0026","url":null,"abstract":"","PeriodicalId":72197,"journal":{"name":"Androgens: clinical research and therapeutics","volume":"115 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78667158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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