全科医学进展(英文)最新文献

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Prevalence and associated factors of uncontrolled hypertension in hypertensive patients in the city of Goma, DRC 刚果民主共和国戈马市高血压患者中未控制的高血压患病率及相关因素
全科医学进展(英文) Pub Date : 2023-03-02 DOI: 10.25082/agpm.2023.01.001
Herman Ngadjole Chelo, Théophile Kabesha Barhwamire, P. Mishika, Zacharie Kibendelwa Tsongo, S. Wembonyama
{"title":"Prevalence and associated factors of uncontrolled hypertension in hypertensive patients in the city of Goma, DRC","authors":"Herman Ngadjole Chelo, Théophile Kabesha Barhwamire, P. Mishika, Zacharie Kibendelwa Tsongo, S. Wembonyama","doi":"10.25082/agpm.2023.01.001","DOIUrl":"https://doi.org/10.25082/agpm.2023.01.001","url":null,"abstract":"Background: The objectives of this study were to determine the proportion of uncontrolled hypertension in hypertensive patients followed up on an outpatient basis and to investigate the factors associated with this poor control. Methods: This was a cross-sectional analytical study of 167 hypertensive patients followed in eight health facilities in Goma city. Uncontrolled hypertension was defined as systolic blood pressure (SBP) ≥140 mmHg and/or diastolic blood pressure (DBP) ≥90 mmHg. Results: The proportion of uncontrolled hypertension was 95.2%. In bivariate analysis, no factor was associated with uncontrolled hypertension. Conclusion: Almost all hypertensive patients in our study were poorly controlled by antihypertensive treatment. These results highlight the need for a cohort study to determine the factors associated with this excessively high prevalence of uncontrolled hypertension in hypertensive patients on antihypertensive drugs, in order to allow targeted actions to try to control hypertension by antihypertensive drugs.","PeriodicalId":71557,"journal":{"name":"全科医学进展(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46239174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gilles de la Tourette syndrome in Central Africa: A case report 中非Gilles de la Tourette综合征一例报告
全科医学进展(英文) Pub Date : 2022-12-28 DOI: 10.25082/agpm.2022.01.006
M. Bugeme, K. Affognon, Jacques Mbaz Musung, Franck Shongo Omanjelo, D. Teuwen, Sarah Kilumba Numbi, Jenny Tshijik Ndua, O. Mukuku, E. Muyumba
{"title":"Gilles de la Tourette syndrome in Central Africa: A case report","authors":"M. Bugeme, K. Affognon, Jacques Mbaz Musung, Franck Shongo Omanjelo, D. Teuwen, Sarah Kilumba Numbi, Jenny Tshijik Ndua, O. Mukuku, E. Muyumba","doi":"10.25082/agpm.2022.01.006","DOIUrl":"https://doi.org/10.25082/agpm.2022.01.006","url":null,"abstract":"Gilles de la Tourette syndrome (GTS), also known as Tourette disorder or Tourette syndrome, is a neurodevelopmental disorder that is characterized by the presence of multiple motor and one or more vocal/phonic tics. These tics are generally more common during childhood and reach a maximum severity between 10 and 12 years. Ticks tend to decrease during late adolescence and adulthood in a majority of patients. We report an observation of GTS diagnosed in a 12-year-old child who was taken care of by clonazepam with a good improvement in its symptomatology. This condition has been reported only very rarely in black sub-Saharan Africans and this is probably the first case of GTS reported in Central Africa.","PeriodicalId":71557,"journal":{"name":"全科医学进展(英文)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47049143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Three first cases of Meige syndrome in Central Africa 中非首次出现三例梅杰综合征病例
全科医学进展(英文) Pub Date : 2022-12-23 DOI: 10.25082/agpm.2022.01.005
M. Bugeme, Y. Kaba, Franck Shongo Omanjelo, Jacques Mbaz Musung, Sarah Kilumba Numbi, O. Mukuku, E. Muyumba, D. Teuwen
{"title":"Three first cases of Meige syndrome in Central Africa","authors":"M. Bugeme, Y. Kaba, Franck Shongo Omanjelo, Jacques Mbaz Musung, Sarah Kilumba Numbi, O. Mukuku, E. Muyumba, D. Teuwen","doi":"10.25082/agpm.2022.01.005","DOIUrl":"https://doi.org/10.25082/agpm.2022.01.005","url":null,"abstract":"Meige syndrome (MS) is a rare type of focal dystonia characterized by unintentional bilateral activity in facial and mandibular muscles in combination with blepharospasm (spasm in the orbicular muscle). Often unknown cause, MS can be primary (idiopathic) or secondary (to medications or brain degenerative pathologies). Its treatment is based in most cases on botulinum toxin injections, not available in our environment. Nevertheless, clonazepam treatment has allowed us to improve the symptoms of our patients. We report MS in three patients, all with no particular history of consulting for involuntary facial movements. The diagnosis of MS was essentially based on the clinical picture. After treatment with clonazepam, the clinical course in all three patients was marked by the almost complete disappearance of these abnormal movements. In all cases, clinical progress was favorable with an average decline of 12 months; no recidivism was noted.","PeriodicalId":71557,"journal":{"name":"全科医学进展(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43129243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gender-specific anterior cruciate ligament – gait forces 性别特异性前十字韧带-步态力
全科医学进展(英文) Pub Date : 2022-01-01 DOI: 10.25082/agpm.2022.01.002
Bharadwaj Cheruvu, Amy T. Neidhard-Doll, T. Goswami
{"title":"Gender-specific anterior cruciate ligament – gait forces","authors":"Bharadwaj Cheruvu, Amy T. Neidhard-Doll, T. Goswami","doi":"10.25082/agpm.2022.01.002","DOIUrl":"https://doi.org/10.25082/agpm.2022.01.002","url":null,"abstract":"The purpose of this study was to investigate gender-based differences in gait biomechanics and to evaluate those effects on forces generated on the ACL during walking. Estimation of gender-specific ACL forces in the frontal plane can provide a better understanding of the biomechanical patterns underlying higher female injury risk. The present study used a sample from the Fels Longitudinal Study to test the hypothesis that there are significant gender-differences in frontal plane ACL loading during walking. A cross-sectional sample of 178 participants, including 79 males and 99 females was used to evaluate differences in gait kinetics. Females walked at higher cadence with narrower steps (P < 0.05). No difference was observed in the peak flexion force and knee rotation moment between males and females (P = 0.51 and 0.07), respectively. Peak abduction moment was significantly lower among females than in males (P = 0.05). A regression equation was developed which considers a person’s weight and height in addition to forces which could give better estimate of the forces acting on the ligament. The peak force acting on the ACL during walking reaches as high as 0.44 of BW, regardless of gender.","PeriodicalId":71557,"journal":{"name":"全科医学进展(英文)","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69216628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Etiology of breast development and asymmetry 乳房发育和不对称的病因学
全科医学进展(英文) Pub Date : 2022-01-01 DOI: 10.25082/agpm.2022.01.004
Elisabeth N. Adkins, Shaina Anderson, Trevor McKoy, Nakachi K. Maduka, Tarun Goswami
{"title":"Etiology of breast development and asymmetry","authors":"Elisabeth N. Adkins, Shaina Anderson, Trevor McKoy, Nakachi K. Maduka, Tarun Goswami","doi":"10.25082/agpm.2022.01.004","DOIUrl":"https://doi.org/10.25082/agpm.2022.01.004","url":null,"abstract":"Etiology of breast development and asymmetry is a fascinating research topic physiologically as well as pathophysiology from a certain condition. The shape, contour, and size of the breast are unique to each female. These factors are influenced by genetics, weight, exercise, menstruation cycles, pregnancy, menopause status, and age. An attempt was made to research the breast development at fetal development and transitioning into adulthood and menopause. Additionally, we compare breast development in males to the developments in females. Something that almost everyone experiences is breast asymmetry. Although breast asymmetry is experienced by all women, it ranges from grossly undetectable to the need for surgical intervention. It is thought that breast asymmetry has intrinsic and extrinsic factors that determine the type and the extent of asymmetry observed. Hormones at play and their effect on breast asymmetry throughout breast development has been charted. Breast asymmetry is most often secondary to benign breast disorders and unassociated with a risk for malignancy. As the perception of one’s body image is an integral part of self-confidence, breast asymmetry has the potential to affect every woman’s quality of life, regardless of the degree of asymmetry. Throughout this effort, our aim was to analyze and understand breast development in males and females, breast changes from the prepubertal to post-menopausal period, benign pathological changes, summarizing the etiologies of breast asymmetry, and their effects on quality of life.","PeriodicalId":71557,"journal":{"name":"全科医学进展(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69216695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Research on practice of ambidextrous education in universities and institutions specialized in drug rehabilitation treatment – A case on a physical rehabilitation course for detoxificatee 戒毒专业院校开展双手教育的实践研究——以某戒毒人员肢体康复课程为例
全科医学进展(英文) Pub Date : 2022-01-01 DOI: 10.25082/agpm.2022.01.003
Longxian Chai
{"title":"Research on practice of ambidextrous education in universities and institutions specialized in drug rehabilitation treatment – A case on a physical rehabilitation course for detoxificatee","authors":"Longxian Chai","doi":"10.25082/agpm.2022.01.003","DOIUrl":"https://doi.org/10.25082/agpm.2022.01.003","url":null,"abstract":"To formulate an implementation plan for the curriculum education reform of physical recovery training methods for drug ban officers focusing on objectives, contents, methods and evaluation, and strive to provide reference for the construction of relevant disciplines, the training of talents and the implementation of physical recovery training methods for drug ban officers in state-controlled police related institutions such as judicial organs according to the basic principles of sports courses and the requirements of drug ban professional ability. Disciplines such as physical and mental health training of drug ban staff created with the development of the subject on state controlled administrative law enforcement involving police and the abstinence and correction skills teaching in the provincial pocal judicial police universities. It is an important project how to make a good teaching design and deepen the integration of theoretical knowledge system and physical and mental rehabilitation training for drug addicts.","PeriodicalId":71557,"journal":{"name":"全科医学进展(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69216656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Coronavirus disease 2019 on macroeconomics and overall development in the Democratic Republic of Congo 2019冠状病毒病对刚果民主共和国宏观经济和整体发展的影响
全科医学进展(英文) Pub Date : 2020-12-30 DOI: 10.25082/agpm.2020.01.003
O. Luboya, O. Mukuku, Léon N. Kabamba, A. Mutombo, P. Mawaw
{"title":"Impact of Coronavirus disease 2019 on macroeconomics and overall development in the Democratic Republic of Congo","authors":"O. Luboya, O. Mukuku, Léon N. Kabamba, A. Mutombo, P. Mawaw","doi":"10.25082/agpm.2020.01.003","DOIUrl":"https://doi.org/10.25082/agpm.2020.01.003","url":null,"abstract":"Oscar N. Luboya Olivier Mukuku ∗ Léon N. Kabamba Augustin M. Mutombo Paul M. Mawaw 1 Institut Supérieur des Techniques Médicales de Lubumbashi, Lubumbashi, Democratic Republic of Congo 2 Department of Public Health, Faculty of Medicine, University of Lubumbashi, Democratic Republic of Congo 3 Department of Pediatrics, Faculty of Medicine, University of Lubumbashi, Democratic Republic of Congo 4 Department of Public Health, Faculty of Medicine, University of Kamina, Democratic Republic of Congo","PeriodicalId":71557,"journal":{"name":"全科医学进展(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43877430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cryptococcus neoformans meningitis in an immunocompetent adult: A case report 一例具有免疫功能的成年人新型隐球菌脑膜炎
全科医学进展(英文) Pub Date : 2020-11-18 DOI: 10.25082/agpm.2020.01.002
Georges Yumba Numbi, Berthe Kamalo Mwad, O. Mukuku, C. Mwamba
{"title":"Cryptococcus neoformans meningitis in an immunocompetent adult: A case report","authors":"Georges Yumba Numbi, Berthe Kamalo Mwad, O. Mukuku, C. Mwamba","doi":"10.25082/agpm.2020.01.002","DOIUrl":"https://doi.org/10.25082/agpm.2020.01.002","url":null,"abstract":"Neuromeningeal cryptococcosis (NMC) is relatively rare in immunocompetent subjects. We report a Congolese case of NMC diagnosed in an apparently immunocompetent subject. A 35-year-old woman was admitted for acute meningoencephalitis. The cerebrospinal fluid (CSF) examination revealed cytological and biochemical abnormalities and the presence of Cryptococcus neoformans on direct examination with India ink and in culture. The serum dosage of cryptococcal antigens was titrated at 1:32. HIV and syphilis antibodies were negative and the blood CD4 lymphocyte count was 610/mm3. The patient had no other immunosuppressive factors, in particular no hematologic abnormalities, no solid tumor, or malnutrition. She was unsuccessfully treated with fluconazole intraveinously, and died after 10 days of treatment. This observation reminds us that NMC can occur in subjects without apparent immunosuppressive factor with a misleading clinical presentation. It is a rare infection with a severe prognosis even in immunocompetent patients.","PeriodicalId":71557,"journal":{"name":"全科医学进展(英文)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46590042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Acute renal failure as severe malaria complication in Lubumbashi: Management and follow-up in an under-equipped setting 卢本巴希作为严重疟疾并发症的急性肾衰竭:在设备不足的环境中的管理和随访
全科医学进展(英文) Pub Date : 2020-01-01 DOI: 10.25082/agpm.2020.01.001
Deddy C. Kalonji, Lebrun N. Kembo, Matthieu Ngombe, O. Mukuku
{"title":"Acute renal failure as severe malaria complication in Lubumbashi: Management and follow-up in an under-equipped setting","authors":"Deddy C. Kalonji, Lebrun N. Kembo, Matthieu Ngombe, O. Mukuku","doi":"10.25082/agpm.2020.01.001","DOIUrl":"https://doi.org/10.25082/agpm.2020.01.001","url":null,"abstract":"Purpose Acute renal failure (ARF) or acute kidney injury (AKI) is one of the major criteria for the severity of malaria according to WHO. The objective was to determine the frequency as well as to evaluate the management and follow-up of ARF during malaria in children in Lubumbashi. Material and methods This is a descriptive cross-sectional study over 48 months (January 1st, 2016 to December 30th, 2019) carried out at the pediatric service of the University Clinics of Lubumbashi. All children with an ARF with a positive thick blood smear were included in the study. Data were analyzed with SPSS 19 software. Results During this period, 910 patients (49.1%) were admitted for malaria. Among them, 14 patients, i.e. an intra-hospital prevalence of 0.78%, of which 6 boys (42.9%) and 8 girls (57.1%) had ARF. The mean age is 7.9±3.5 years. The serum creatinine level was between 0.54 and 15.2 mg/dL with a mean of 5.7 mg/dL. Kidney dialysis was only effective in 3 patients (21.4%) and diuretics were given 100% in all children. The mean length of stay was 13.4±8.7 days (range: 1 day and 18 days). Mortality was 21.4%. Conclusion The present study shows that ARF in childhood malaria in Lubumbashi is infrequent but of high mortality in our environment with limited resources where care is lacking and monitoring difficult.","PeriodicalId":71557,"journal":{"name":"全科医学进展(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69216609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current trends in targeted therapy of leukaemia and lymphoma 白血病和淋巴瘤靶向治疗的当前趋势
全科医学进展(英文) Pub Date : 2019-08-23 DOI: 10.25082/AGPM.2019.01.005
Josipa Skelin, M. Antica
{"title":"Current trends in targeted therapy of leukaemia and lymphoma","authors":"Josipa Skelin, M. Antica","doi":"10.25082/AGPM.2019.01.005","DOIUrl":"https://doi.org/10.25082/AGPM.2019.01.005","url":null,"abstract":"Decades of cancer and leukaemia research have provided priceless insight into the molecular mechanisms underlying the development and maintenance of malignancies. The ultimate goal of these findings was, and still is, discovering discriminating factors enabling detection or treatment of tumour cells. An important achievement in this field has been the integration of protein chemistry, fluorescence detectors, nanoparticles, optical devices and computational devolvement integrated in the field of flow cytometry, fluorescence activated cell sorting FACS, data analysis and visualisation. Especially important is the onset of computational data mining tools like T-distributed Stochastic Neighbor Embedding (t- SNE), developed by van der Maatenand Hinton and further continuous progress of the machine learning algorithms for visualization of the huge amount of data produced from single cell FACS or mass cytometry analysis.","PeriodicalId":71557,"journal":{"name":"全科医学进展(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41371026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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