纳米粒子(英文)最新文献_第2页

In Vivo Animal Model Evaluation of a Powerful Oral Nanomedicine for Treating Breast Cancer in BALB/c Mice Using 4T1 Cell Lines without Chemotherapy 一种口服纳米药物治疗BALB/c小鼠乳腺癌的体内动物模型评估，使用4T1细胞系，无需化疗

纳米粒子(英文) Pub Date : 2022-01-01 DOI: 10.4236/anp.2022.113006

Z. Fakhroueian, A. Massiha, Pegah Esmaeilzadeh, M. Assmar, A. Zahedi, Pouriya Esmaeilzadeh, Sara Rezaei, Shahab Rabiei Lalehdasht

{"title":"<i>In Vivo</i> Animal Model Evaluation of a Powerful Oral Nanomedicine for Treating Breast Cancer in BALB/c Mice Using 4T1 Cell Lines without Chemotherapy","authors":"Z. Fakhroueian, A. Massiha, Pegah Esmaeilzadeh, M. Assmar, A. Zahedi, Pouriya Esmaeilzadeh, Sara Rezaei, Shahab Rabiei Lalehdasht","doi":"10.4236/anp.2022.113006","DOIUrl":"https://doi.org/10.4236/anp.2022.113006","url":null,"abstract":"Nanopharmaceuticals containing quantum dot nanoparticles (Q-Dot NPs) for treating serious cancers such as breast cancer have made fantastic propos-als. In this study, ZnO quantum dot NPs are formulated via ZnO@PVP nanopolymer as co-assistants coordinating with efficacious suitable wetting agents, PEG-binding compound, and W/O emulsifier for producing eco-friendly wa-ter-based nanodrug. Several characterization techniques containing SEM, TEM, FTIR, photoluminescence, zeta potential, and UV-Vis absorption were employed for ZnO Q-Dot NPs in nanodrug. This work aims to investigate the anti-tumor effects of such nanomedicine on the 4T1 breast cancer cell line in BALB/c mice, being elaborated through intraperitoneal, injection (IVP) and oral therapy. The impressive findings showed that ZnO nanodrug caused changes in blood factors, having the most effectiveness at 40 µg/ml concentration after two weeks of oral treatments. The significant increase in white blood cells (WBC) neutrophils and meaningful decreases in lymphocytes and especially cholesterol were powerful simultaneous impacts, successfully treating malignant breast cancer masses. In this significant animal model research for breast cancer, the sick mice recovered entirely and even had a safe space to mate. Histopathological results showed no evidence of breast tumor formation or metastasis in the group treated with nanodrug and their children. This nanomedicine has a therapeutic effect, and is ready to be applied for treating volunteer breast cancer patients. However, its prevention (inhibitory) effect can also be analyzed and added to current data in future studies.","PeriodicalId":71264,"journal":{"name":"纳米粒子(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70339299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis of Novel Virus-Like Mesoporous Silica-ZnO-Ag Nanoparticles and Quercetin Synergize with NIR Laser for Omicron Mutated Covid-19 Virus Infectious Diseases Treatment 新型病毒样介孔二氧化硅- zno - ag纳米颗粒的合成与槲皮素与近红外激光协同治疗组微米突变的Covid-19病毒传染病

纳米粒子(英文) Pub Date : 2022-01-01 DOI: 10.4236/anp.2022.111002

Fadilah Ibrahim

引用次数: 2

Synthesis and Stability Studies of 225Actinium Tin Colloid Radiopharmaceutical 225锕-锡胶体放射性药物的合成及稳定性研究

纳米粒子(英文) Pub Date : 2022-01-01 DOI: 10.4236/anp.2022.111003

Davut Cakici, B. Kilbas

引用次数: 1

Bio-Fabrication of Silver Nanoparticles Using Catha edulis Extract: Procedure Optimization and Antimicrobial Efficacy Encountering Antibiotic-Resistant Pathogens 利用羽衣甘蓝提取物制备纳米银:工艺优化及耐药病原菌的抗菌效果

纳米粒子(英文) Pub Date : 2022-01-01 DOI: 10.4236/anp.2022.112004

A. Numan, Mashhour Ahmed, M. S. A. Galil, Mohyeddine Al-qubati, A. Raweh, E. Helmi

引用次数: 4

Removal of Fluoride from Water Using Mesoporous MCM-41: An Optimization Approach Using Response Surface Methodology (RSM) 响应面法优化介孔MCM-41去除水中氟化物的研究

纳米粒子(英文) Pub Date : 2021-08-03 DOI: 10.4236/anp.2021.103007

Bodhaditya Das, Saumen Banerjee, P. Raul, R. R. Devi, I. M. Umlong, A. K. Talukdar, Sanjai K. Dwivedi

{"title":"Removal of Fluoride from Water Using Mesoporous MCM-41: An Optimization Approach Using Response Surface Methodology (RSM)","authors":"Bodhaditya Das, Saumen Banerjee, P. Raul, R. R. Devi, I. M. Umlong, A. K. Talukdar, Sanjai K. Dwivedi","doi":"10.4236/anp.2021.103007","DOIUrl":"https://doi.org/10.4236/anp.2021.103007","url":null,"abstract":"Fluoride above 1.5 mg·L-1 is injurious to \u0000health. Removal of fluoride from water using mesoporous MCM-41 as a strong \u0000adsorbent material has been attempted. Characterization using transmission \u0000electron microscopic study of calcined MCM-41 showed the regular hexagonal \u0000array of mesoporous channels with an average size of 20 nm and the surface area (BET \u0000study) of 1306.96 m2·g-1. The average pore size of the \u0000particles was found to be 14.21 nm. A study on the effect of contact time on the removal \u0000of fluoride revealed that more than 85% uptake of fluoride onto MCM-41 was \u0000achieved at a contact time of 120 min. From the Langmuir adsorption study, the maximum sorption \u0000capacity of fluoride was found to be 63.05 mg/g at 301 K. From the thermodynamic study, the \u0000+ΔHo value of 2.29 kJ·mol-1 indicated the endothermic nature of the \u0000removal process. Application of Response Surface Model suggested that 77.88% of \u0000fluoride removal can be achieved at fluoride concentration of 10 mg·L-1, \u0000pH (6.3), and \u0000contact time of 120 min.","PeriodicalId":71264,"journal":{"name":"纳米粒子(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42771819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Synthesis and Application of Nanocomposite Reinforced with Decorated Multi Walled Carbon Nanotube with Luminescence Quantum Dots 发光量子点修饰多壁碳纳米管增强纳米复合材料的合成与应用

纳米粒子(英文) Pub Date : 2021-04-30 DOI: 10.4236/ANP.2021.102006

J. A. Dalaeen, Yashfeen Khan, Anees Ahmad

{"title":"Synthesis and Application of Nanocomposite Reinforced with Decorated Multi Walled Carbon Nanotube with Luminescence Quantum Dots","authors":"J. A. Dalaeen, Yashfeen Khan, Anees Ahmad","doi":"10.4236/ANP.2021.102006","DOIUrl":"https://doi.org/10.4236/ANP.2021.102006","url":null,"abstract":"Amidst the COVID-19 pandemic, environmental problems such as energy crisis, global warming, and contamination from \u0000pathogenic micro-organisms are still \u0000prevailed and strongly demanded progress in high-performance energy storing and anti-microbial materials. The nanocomposites are \u0000materials that have earned large interest \u0000owing to their promising applications for countering global issues \u0000related to sustainable energy and a flourishing environment. Here, polypyrrole coated hybrid nanocomposites of multi-walled carbon nanotube and cadmium sulfide quantum dots named MCP were synthesized using facile and low-cost in-situ oxidative polymerization method. Characterization techniques confirmed the \u0000synthesis. Electrochemical studies showed that the nanocomposite 1-MCP showed an impressively \u0000higher super capacitance behavior in comparison to f-MWCNT, 7-MCP and 5-MCP. \u0000The improved performance of the nanocomposites was attributed mainly to the \u0000good conductivity of carbon nanotubes and polypyrrole, high surface area, and \u0000stability of the carbon nanotubes and the high electrocatalytic activity of the \u0000cadmium sulfide quantum dots. Owing to the synergistic effect of MWCNT, CdS, and PPy the synthesized ternary nanocomposite \u0000also inhibited the growth and multiplication of tested bacteria such as S. aureus, and E. coli completely within 24 h. On the whole, the assimilated \u0000nanocomposite MCP opens promising aspects for the development of upcoming \u0000energy storage devices and as an antibacterial agent.","PeriodicalId":71264,"journal":{"name":"纳米粒子(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41926418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pattern of Growth and Dry Matter Accumulation in Some Improved Cowpea Varieties (Vigna unguiculata) Exposed to Alpha Nano Spin α纳米自旋对改良豇豆品种生长和干物质积累的影响

纳米粒子(英文) Pub Date : 2021-04-30 DOI: 10.4236/ANP.2021.102004

H. Kana, Emmanuel Enock Goler, Peter Barka Mshemlbula

引用次数: 0

Pure SnO2 Gas Sensor with High Sensitivity and Selectivity towards C2H5OH 对C2H5OH具有高灵敏度和选择性的纯SnO2气体传感器

纳米粒子(英文) Pub Date : 2021-01-01 DOI: 10.4236/ANP.2021.102005

Abeer A. Alhadi, Shuyi Ma, Ting-ting Yang, S. Pei, P. Yun, Khalid Ahmed Abbakar, Qianqian Zhang, N. Ma, Manahil H. Balal, Hamouda Adam Hamouda, K. M. Adam

引用次数: 4

A Brief Review of How to Construct an Enzyme-Based H2O2 Sensor Involved in Nanomaterials 纳米材料酶基H2O2传感器的研究进展

纳米粒子(英文) Pub Date : 2021-01-01 DOI: 10.4236/anp.2021.101001

U. Nestor, Hitimana Frodouard, Muhizi Theoneste

{"title":"A Brief Review of How to Construct an Enzyme-Based H2O2 Sensor Involved in Nanomaterials","authors":"U. Nestor, Hitimana Frodouard, Muhizi Theoneste","doi":"10.4236/anp.2021.101001","DOIUrl":"https://doi.org/10.4236/anp.2021.101001","url":null,"abstract":"This article briefly reviews how to construct an enzyme based hydrogen peroxide sensor involving nanomaterials, which has the advantages of high efficiency, good sensitivity and selectivity, fast response time and an extended range of linearity with lower detection limit. Glucose biosensor is constructed by immobilizing glucose oxidase enzyme on the polycarbonate membrane and the protective cover is then filled with a physiological phosphate buffer, pH 7.4. The novel blocking hydrophobic membrane which is only permeable to hydrogen peroxide is used to eliminate electrochemical interferences. This constructed enzyme based H2O2 biosensor is miniaturized by the involvement of nanomaterials like carbon nanotubes, platinum nanoparticles and silver nanoparticles and it can achieve the effective microscopic detection of glucose. The introduction of nanomaterials including some pure metals (Ag, Au, Pd, Ni, Pt, and Cu), metal oxide (ZnO and TiO2), bimetallic (Au/Ag and Au/Pt) and carbon (nanotubes and graphene) nanomaterials in the construction of the enzyme based H2O2 biosensor improves its sensitivity and performance by enhancing the enzymatic activity, and allows the introduction of many new signal transduction technologies in biosensors. This review article summarizes the working principles of glucose oxidase based hydrogen peroxide sensor, importance of involving nanomaterials in biosensor manufacturing, basic characteristics and components of a biosensor, generations glucose biosensors, procedure of making hydrogen peroxide based biosensor, synthesis of nanomaterials involved in hydrogen peroxide biosensor, and finally some examples of nanomaterials which intervene in hydrogen peroxide biosensor.","PeriodicalId":71264,"journal":{"name":"纳米粒子(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70338579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Structural and Elastic Behavior of Chromium Doped Pr0.5Sr0.5MnO3 System 铬掺杂Pr0.5Sr0.5MnO3体系的结构和弹性行为

纳米粒子(英文) Pub Date : 2021-01-01 DOI: 10.4236/ANP.2021.101002

Ashok Kumar Kusuma, E. Sagar, G. S. Reddy, K. Kumar

引用次数: 0