Acta orthopaedica et traumatologica turcica最新文献

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Acute kidney injury after major orthopedic surgery: A retrospective study of frequency and related risk factors. 重大骨科手术后急性肾损伤:频率及相关危险因素的回顾性研究。
IF 1 4区 医学
Acta orthopaedica et traumatologica turcica Pub Date : 2022-07-01 DOI: 10.5152/j.aott.2022.22048
Volkan Hancı, Şule Özbilgin, Onur Başçı, Dilek Ömür, Nilay Boztaş
{"title":"Acute kidney injury after major orthopedic surgery: A retrospective study of frequency and related risk factors.","authors":"Volkan Hancı,&nbsp;Şule Özbilgin,&nbsp;Onur Başçı,&nbsp;Dilek Ömür,&nbsp;Nilay Boztaş","doi":"10.5152/j.aott.2022.22048","DOIUrl":"https://doi.org/10.5152/j.aott.2022.22048","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to analyze the frequency of postoperative kidney injury, the related factors, and its effect on outcomes in major orthopedic surgery cases treated in the postanesthesia intensive care unit (PACU).</p><p><strong>Methods: </strong>Major orthopedic surgery cases treated in the PACU were included in this study retrospectively. Demographic, operation, and anesthesia characteristics, CCI, ASA risk classes, preoperative biochemistry, and hemogram results of the patients were recorded. Postoperative serum creatinine level, urine output, renal replacement therapy requirement, and hemoglobin levels were recorded. The kidney damage of the patients was evaluated with RIFLE and AKIN criteria. Postoperative complications were recorded.</p><p><strong>Results: </strong>The frequency of kidney injury in the early postoperative period was 7.1%. When only arthroplasty cases were taken, the frequency was 11%. It was determined that there was a correlation between preoperative ASA, CCI, BMI, K levels, lactate levels, and postoperative kidney damage (P <0.05). It was determined that the frequency and duration of inotropic use, the frequency and duration of noninvasive mechanical ventilation, and the duration of hospitalization increased in patients with postoperative kidney damage, and the frequency of pneumonia, wound infection, atelectasis, sepsis, arrhythmia, atrial fibrillation and mortality increased in the postoperative period (P <0.05).</p><p><strong>Conclusion: </strong>There is a need for further studies on the relationship between ASA, CCI, BMI, K, and lactate values and postoperative kidney damage. Postoperative kidney injury is associated with prolonged hospitalization and increased morbidity and mortality.</p><p><strong>Level of evidence: </strong>Level IV, Therapeutic Study.</p>","PeriodicalId":7097,"journal":{"name":"Acta orthopaedica et traumatologica turcica","volume":"56 4","pages":"289-295"},"PeriodicalIF":1.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f3/1a/aott-56-4-289.PMC9612670.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40415645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Impact of the unplanned excision on the oncological outcomes of patients with soft tissue sarcomas: a single-center retrospective review of 490 patients. 非计划切除对软组织肉瘤患者肿瘤预后的影响:490例患者的单中心回顾性评价
IF 1 4区 医学
Acta orthopaedica et traumatologica turcica Pub Date : 2022-07-01 DOI: 10.5152/j.aott.2022.21373
Andaç Celasun Alsina, Federico Sacchetti, Hüseyin Kaya, Banu Yaman, İpek Tamsel, Dündar Sabah
{"title":"Impact of the unplanned excision on the oncological outcomes of patients with soft tissue sarcomas: a single-center retrospective review of 490 patients.","authors":"Andaç Celasun Alsina,&nbsp;Federico Sacchetti,&nbsp;Hüseyin Kaya,&nbsp;Banu Yaman,&nbsp;İpek Tamsel,&nbsp;Dündar Sabah","doi":"10.5152/j.aott.2022.21373","DOIUrl":"https://doi.org/10.5152/j.aott.2022.21373","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to (1) compare the oncological results of patients who underwent re-excision after unplanned excision with those who underwent planned excision and (2) analyze the impact of local recurrences on oncological outcomes.</p><p><strong>Methods: </strong>Patients with soft tissue sarcoma who had been treated in our center between 2000 and 2018 were retrospectively reviewed. Patients were divided into two groups: Group PE (Planned excision; n=345) and group UE (Unplanned excision; n=145). Two groups were compared in terms of local recurrence-free survival (LRFS), metastasis-free survival (MFS), and overall survival (OS). Local recurrences effects over MFS and OS were also analyzed.</p><p><strong>Results: </strong>There were 26 (17.9%) local recurrences in the UE group and 30 (8.7%) local recurrences in the PE group (P=0.005). There was no difference in MFS and OS between study groups (P=0.278 and P=0.848, respectively). Five years MFS rates of UE and PE groups were 76.4% and 73.6%, and five-year OS rates of UE and PE groups were 70.3% and 73.9%, respectively (P=0.417, P=0.656). Patients with local recurrence had a 1.96 times higher risk of metastasis than patients without local recurrence (P=0.008). Patients with local recurrence had 1.65 times higher risk of mortality than patients without local recurrence (P=0.047).</p><p><strong>Conclusion: </strong>Although local recurrence is much more common in the UE group, this outcome does not seem to affect MFS or OS. These results indicate that similar outcomes can be achieved if UE patients are referred and appropriately treated with wide re-resections.</p><p><strong>Level of evidence: </strong>Level III, Therapeutic Study.</p>","PeriodicalId":7097,"journal":{"name":"Acta orthopaedica et traumatologica turcica","volume":"56 4","pages":"272-277"},"PeriodicalIF":1.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2e/ca/aott-56-4-272.PMC9612672.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40699927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of multi-modal intra-operative neurophysiological monitoring in corrective surgeries for thoracic tuberculosis with kyphosis. 多模式术中神经生理监测在胸结核伴后凸矫正手术中的作用。
IF 1 4区 医学
Acta orthopaedica et traumatologica turcica Pub Date : 2022-07-01 DOI: 10.5152/j.aott.2022.22053
Xianming Huang, Shishu Huang, Chao Luo, Yueming Song, Quan Gong, Zhongjie Zhou
{"title":"The role of multi-modal intra-operative neurophysiological monitoring in corrective surgeries for thoracic tuberculosis with kyphosis.","authors":"Xianming Huang,&nbsp;Shishu Huang,&nbsp;Chao Luo,&nbsp;Yueming Song,&nbsp;Quan Gong,&nbsp;Zhongjie Zhou","doi":"10.5152/j.aott.2022.22053","DOIUrl":"https://doi.org/10.5152/j.aott.2022.22053","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to assess the performance and utility of motor evoked potentials (MEP) and somatosensory evoked potentials (SSEP) during corrective surgery for thoracic tuberculosis with kyphosis (TTK).</p><p><strong>Methods: </strong>68 patients (mean age 31.7 ± 20.3 years) who underwent corrective surgery for TTK from 2012 to 2019 were included in this retrospective study. Patients were neurologicaly evaluated before and after surgery with systematic neurologic examinations. Intraoperative neurophysiological monitoring (IONM) with SSEP and MEP was carried out. A receiver operating characteristic (ROC) curve and area under ROC curve (AUC) were used to identify the diagnostic accuracy of potential recovery.</p><p><strong>Results: </strong>IONM alerting occurred in 12 surgeries (12/68, 17.6%), of which 6 were SSEP alerting, 2 MEP alerting, and 4 combinations of both SSEP and MEP. Among the 12 cases where there was IONM alerting, 3 (25%) had postoperative neurological deficits(PND), whereas one patient had PND without IONM alerting. IONM sensitivity and specificity were 0.75 (95% CI 0.22-0.99) and 0.86 (95% CI 0.74-0.93) respectively. Positive predictive value (PPV) and negative predictive value (NPV) were 0.25 and 0.98 respectively. The AUC of evoked potential recovery in diagnosing PND was 0.884.</p><p><strong>Conclusion: </strong>Our study showed that multi-modal IONM with SSEP and MEP can effectively indicate a potential neural injury and predict PND during TTK corrective surgery.</p><p><strong>Level of evidence: </strong>Level IV, Therapeutic Study.</p>","PeriodicalId":7097,"journal":{"name":"Acta orthopaedica et traumatologica turcica","volume":"56 4","pages":"283-288"},"PeriodicalIF":1.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d1/57/aott-56-4-283.PMC9612662.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40415644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Kinesiophobia and its association with functional outcome and quality of life 6-8 years after total hip arthroplasty. 全髋关节置换术后6-8年运动恐惧症及其与功能结局和生活质量的关系。
IF 1 4区 医学
Acta orthopaedica et traumatologica turcica Pub Date : 2022-07-01 DOI: 10.5152/j.aott.2022.21318
Bariq Al-Amiry, Andreas Rahim, Björn Knutsson, Leif Mattisson, Arkan Sayed-Noor
{"title":"Kinesiophobia and its association with functional outcome and quality of life 6-8 years after total hip arthroplasty.","authors":"Bariq Al-Amiry,&nbsp;Andreas Rahim,&nbsp;Björn Knutsson,&nbsp;Leif Mattisson,&nbsp;Arkan Sayed-Noor","doi":"10.5152/j.aott.2022.21318","DOIUrl":"https://doi.org/10.5152/j.aott.2022.21318","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to assess the incidence and severity of kinesiophobia, and to determine the relationship between Tampa Scale of Kinesiophobia (TSK) scores, functional outcome and quality of life (QoL) 6-8 years after Total Hip Arthroplasty (THA).</p><p><strong>Methods: </strong>161 patients (78 male and 83 female) with unilateral primary osteoarthritis (OA) treated with THA between September 2010 and December 2013 were included in this study. Western Ontario and McMaster Universities Osteoarthritis (WOMAC) and EQ-5D scores were measured preoperatively. At 6-8 years follow-up, these scores were repeated and TSK scores were also measured. According to the TSK, patients were divided into two groups for further comparisons and analysis: without kinesiophobia (TSK-score ≤ 36) and with kinesiophobia (TSK-score >36).</p><p><strong>Results: </strong>There were 99 patients (61.5%) with no kinesiophobia (TSK score ≤ 36, TSK mean 28.4, SD 4.7) and 62 patients (38.5%) with kinesiophobia (TSK score > 36, TSK mean 42.8, SD 5.3). Patients with and without kinesiophobia were not statistically different regarding age, sex or body mass index. (P = 0.20, P = 0.99, P = 0.22, respectively). In the group with no kinesiophobia, the mean 6-8 years WOMAC was 12.4 (SD 15.6), while the absolute delta (Δ) value between preoperative and 6-8 years WOMAC was 46.2 (SD 20.4), compared to the group with kinesiophobia where the mean 6-8 years WOMAC was 32.2 (SD 23.4), while the absolute delta (Δ) value between preoperative and 6-8 years WOMAC was 32.3 (SD 25.5): both P < 0.001. The group with no kinesiophobia had a mean 6-8 years EQ-5D of 0.81 (SD 0.22), while the absolute delta (Δ) value between preoperative and 6-8 years EQ-5D was 0.44 (SD 0.26), compared to the group with kinesiophobia where the mean 6-8 years EQ-5D was 0.57 (SD 0.23), while the absolute delta (Δ) value between preoperative and 6-8 years EQ-5D was 0.33 (SD 0.26): P < 0.001 and P = 0.03, respectively. TSK scores were associated with worse WOMAC and EQ-5D scores, higher proportion of dependence on walking aids and increased THArelated adverse events (all P < 0.05).</p><p><strong>Conclusion: </strong>This study has shown us that there is a high incidence of kinesiophobia 6-8 years after surgery and treating kinesiophobia early after THA might improve the outcome.</p><p><strong>Level of evidence: </strong>Level IV, Therapeutic Study.</p>","PeriodicalId":7097,"journal":{"name":"Acta orthopaedica et traumatologica turcica","volume":"56 4","pages":"252-255"},"PeriodicalIF":1.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/23/5f/aott-56-4-252.PMC9612671.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40699924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From the Editor. 来自编辑。
IF 1 4区 医学
Acta orthopaedica et traumatologica turcica Pub Date : 2022-07-01 DOI: 10.5152/j.aott.2022.22900
H. Berk
{"title":"From the Editor.","authors":"H. Berk","doi":"10.5152/j.aott.2022.22900","DOIUrl":"https://doi.org/10.5152/j.aott.2022.22900","url":null,"abstract":"","PeriodicalId":7097,"journal":{"name":"Acta orthopaedica et traumatologica turcica","volume":"56 4 1","pages":"238-239"},"PeriodicalIF":1.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47039508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Results of percutaneous cervical vertebroplasty using an anterolateral approach for cervical spine tumors. 前外侧入路经皮颈椎成形术治疗颈椎肿瘤的疗效。
IF 1 4区 医学
Acta orthopaedica et traumatologica turcica Pub Date : 2022-07-01 DOI: 10.5152/j.aott.2022.22035
Ali Fatih Ramazanoğlu, Caner Sarıkaya, Mustafa Umut Etli, Cumhur Kaan Yaltırık, Mehmet Reşid Önen, Sait Naderi
{"title":"Results of percutaneous cervical vertebroplasty using an anterolateral approach for cervical spine tumors.","authors":"Ali Fatih Ramazanoğlu,&nbsp;Caner Sarıkaya,&nbsp;Mustafa Umut Etli,&nbsp;Cumhur Kaan Yaltırık,&nbsp;Mehmet Reşid Önen,&nbsp;Sait Naderi","doi":"10.5152/j.aott.2022.22035","DOIUrl":"https://doi.org/10.5152/j.aott.2022.22035","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to report the results of percutaneous vertebroplasty in managing symptomatic osteolytic cervical spine tumors.</p><p><strong>Methods: </strong>This study comprised a retrospective examination of patients who received percutaneous vertebroplasty between 2008 and 2020 for the treatment of tumor-induced symptomatic cervical vertebra involvement. The study summarized the demographics, vertebral levels, pain control rates, clinical results, and complications of percutaneous vertebroplasty using an anterolateral approach.</p><p><strong>Results: </strong>The study sample consisted of 6 female and 2 male patients aged between 20 and 56 (mean=41.37) years. Tumors were located at C2 in 6 cases, at C3 in 1 case, and at C5 in another. The mean volume of poly (methyl methacrylate) injected was 1.5 mL (range: 1-2 mL). Biopsy results showed the presence of metastasis in 5 cases and plasmacytoma in 3. No postoperative complications or mortality were observed after the procedure. Preoperative mean 7.75 visual analog scale score decreased to 2.62. Pain control was reported to be 66.2%.</p><p><strong>Conclusion: </strong>Anterolateral cervical vertebroplasty seems to be a safe, effective, and helpful therapeutic alternative for the treatment of cervical spine tumors. It reduces the risk of infection compared to the transoral method.</p><p><strong>Level of evidence: </strong>Level IV, Therapeutic Study.</p>","PeriodicalId":7097,"journal":{"name":"Acta orthopaedica et traumatologica turcica","volume":"56 4","pages":"268-271"},"PeriodicalIF":1.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ee/21/aott-56-4-268.PMC9612668.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40699926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predictive factors associated with thirty-day mortality in geriatric patients with hip fractures. 老年髋部骨折患者30天死亡率的预测因素
IF 1 4区 医学
Acta orthopaedica et traumatologica turcica Pub Date : 2022-07-01 DOI: 10.5152/j.aott.2022.21407
Mustafa Kavak, Salih Oğuz, Zübeyir Akkoyun, Ulukan İnan
{"title":"Predictive factors associated with thirty-day mortality in geriatric patients with hip fractures.","authors":"Mustafa Kavak,&nbsp;Salih Oğuz,&nbsp;Zübeyir Akkoyun,&nbsp;Ulukan İnan","doi":"10.5152/j.aott.2022.21407","DOIUrl":"https://doi.org/10.5152/j.aott.2022.21407","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to determine the predictive factors affecting the 30-day mortality in geriatric hip fractures, investigate the effect of the timing of surgery, and thus determine the optimum cut-off time in delaying the surgery.</p><p><strong>Methods: </strong>A total of 596 patients(205 men, 391 women; mean age = 78.3 years) were included in this retrospective study. All possible predictive factors encountered in the literature review, including age, sex, fracture type, comorbidities, American Society of Anesthesiologists (ASA) score, surgical delay time, anaesthesia type, surgery type, need for erythrocyte replacement, postoperative complications, and the need for postoperative intensive care were analyzed. The predictive factors that were found to be significant as a result of the univariate analysis were included in the multivariate logistic regression analysis.</p><p><strong>Results: </strong>The reason for surgery was an extracapsular fracture in 359 patients (60.2%) and an intracapsular fracture in 237 (39.8%). Arthroplasty was performed in 256 patients (43%), while proximal femoral nails were used in 251 (42.1%), dynamic hips screws in 68 (11.4%), and cannulated screws in 21 (3.5%). 523 (87.8%) of the patients had an ASA score of 1 or 2, and 73 (12.2%) had an ASA score of 3 or 4. General anaesthesia was performed on 35.2% of the patients, while regional anaesthesia was administered to 64.8%. Major complications developed in 42 patients (7%), while minor complications were observed in 143 (24%). The mean surgical delay time was 3.21 days (1-9 days). The ASA score (P <0.001, OR: 56.83, CI: 5.26-2.820), anesthesia type (P = 0.036, OR: 3.225, CI: 0.079-2.264), surgical delay time (P <0.001, OR: 2.006, CI: 1.02-0.372) and major complication (P = 0.002, OR: 6.41, CI: 0.661-3.053) were determined to be predictive factors of 30-day mortality.</p><p><strong>Conclusion: </strong>This study found the median surgical delay time as three days in surviving patients and five days in deceased ones. Thus, a 3-day surgical delay may be acceptable and sufficient for medical optimization and the consensus of the multidisciplinary team.</p><p><strong>Level of evidence: </strong>Level IV, Therapeutic Study.</p>","PeriodicalId":7097,"journal":{"name":"Acta orthopaedica et traumatologica turcica","volume":"56 4","pages":"240-244"},"PeriodicalIF":1.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4c/a4/aott-56-4-240.PMC9612673.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40699923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
The effect of adding carboxymethylcellulose and alginate to hyaluronic acid on reducing epidural fibrosis in a lumbar laminectomized rat model. 在透明质酸中加入羧甲基纤维素和海藻酸盐对腰椎椎板切除大鼠模型硬膜外纤维化的影响。
IF 1 4区 医学
Acta orthopaedica et traumatologica turcica Pub Date : 2022-07-01 DOI: 10.5152/j.aott.2022.21392
Surachai Sae-Jung, Natthapoch Busarakham
{"title":"The effect of adding carboxymethylcellulose and alginate to hyaluronic acid on reducing epidural fibrosis in a lumbar laminectomized rat model.","authors":"Surachai Sae-Jung,&nbsp;Natthapoch Busarakham","doi":"10.5152/j.aott.2022.21392","DOIUrl":"https://doi.org/10.5152/j.aott.2022.21392","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to compare the anti-epidural fibrosis and anti-inflammation effects of hyaluronic acid (HA)-carboxymethylcellulose (CMC)-alginate hydrogel, pure HA, and normal saline using a lumbar laminectomized rat model.</p><p><strong>Methods: </strong>Thirty lumbar laminectomized adult rats were randomly assigned to three groups. The control group received normal saline, the HCA group received HA-CMC-alginate gel, and the HA group received pure HA gel soaked over the dura of the laminectomized area before closing the surgical wound. All rats were housed for eight weeks, then epidural fibrosis (EF) was histologically graded. In addition, the fibroblast and inflammatory cell density were computerized for evaluation.</p><p><strong>Results: </strong>The mean fibroblast densities were 32.03 × 102 ± 488, 13.22 × 102 ± 200, and 14.52 × 102 ± 368 cell/mm2 in the control, HCA, and HA groups, respectively. The mean inflammatory cell density was 30.74 × 102 ± 459, 5.90 × 102 ± 129, and 11.08 × 102 ± 282 cell/mm2 in the control, HCA, and HA groups, respectively. The mean fibroblast and inflammatory cell densities in the HCA and HA groups were significantly lower than in the control group (P < 0.05). The HCA group had a significantly lower inflammatory cell density than the HA group (P < 0.05). The fibrous adherence grading of HCA and HA was significantly lower than the control (P < 0.05).</p><p><strong>Conclusion: </strong>HA-CMC-alginate gel and HA hydrogels seem to have a better preventative effect on EF than no treatment (control). HA-CMCalginate can exhibit a better anti-inflammatory effect than HA. HA-CMC-alginate can be effective in reducing EF and inflammation after lumbar laminectomy.</p>","PeriodicalId":7097,"journal":{"name":"Acta orthopaedica et traumatologica turcica","volume":"56 4","pages":"256-261"},"PeriodicalIF":1.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9f/1d/aott-56-4-256.PMC9612669.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40699925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical outcomes and survival following treatment of bone metastases from uterine leiomyosarcoma: A report of 6 cases. 子宫平滑肌肉瘤骨转移治疗6例临床疗效及生存率分析
IF 1 4区 医学
Acta orthopaedica et traumatologica turcica Pub Date : 2022-07-01 DOI: 10.5152/j.aott.2022.22002
Zehra Öztürk Başarır, Mustafa Onur Karaca, Kamil Balaban, Kerem Başarır
{"title":"Clinical outcomes and survival following treatment of bone metastases from uterine leiomyosarcoma: A report of 6 cases.","authors":"Zehra Öztürk Başarır,&nbsp;Mustafa Onur Karaca,&nbsp;Kamil Balaban,&nbsp;Kerem Başarır","doi":"10.5152/j.aott.2022.22002","DOIUrl":"https://doi.org/10.5152/j.aott.2022.22002","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to analyze the patient-reported outcomes and survival following surgical treatment of bone metastases from (uLMS) uterine leiomyosarcoma.</p><p><strong>Methods: </strong>A retrospective review of six patients undergoing surgical procedures for metastatic uLMS over seven years was conducted at a single center. All patients were reviewed for their primary malignancy and characteristics of bone metastasis during follow-up. Clinical presentation of bone metastasis, modality, and the type of treatment related to musculoskeletal involvement were also analyzed. The visual analog pain scale (VAS) and Eastern Cooperative Oncology Group (ECOG) performance status scale were used pre-and postoperatively to evaluate the patient-reported outcome.</p><p><strong>Results: </strong>Four patients had solitary bone metastases, whereas multiple bone metastases were diagnosed in two. Of those who had solitary bone metastasis, all of them were treated with wide resection. One of the two patients with multiple bone metastases was also treated with wide resection, and the other was treated with intralesional curettage. Four patients died from primary disease, and two were alive without evidence of disease recurrence. The median survival time following a diagnosis of bone metastasis was 15.0 months (95% CI, 0.6 to 29.4 months). The mean VAS scores for all six patients improved. However, the improvement in ECOG performance status was seen in only four patients.</p><p><strong>Conclusion: </strong>Although the prognosis of uLMS patients with bone metastasis seems poor, wide resection of the solitary bone metastasis may help prolong the overall survival. Performing orthopedic surgeries for the bone metastasis from uLMS in case of intractable pain after palliative radiotherapy, impending or pathological fracture, or solitary disease has been shown to decrease the pain significantly and improve the performance status in the majority.</p><p><strong>Level of evidence: </strong>Level IV, Therapeutic Study.</p>","PeriodicalId":7097,"journal":{"name":"Acta orthopaedica et traumatologica turcica","volume":"56 4","pages":"278-282"},"PeriodicalIF":1.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/99/56/aott-56-4-278.PMC9612665.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40699928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of the hook of hamate fracture with robot navigation: A note on technique. 机器人导航治疗钩骨骨折技术要点。
IF 1 4区 医学
Acta orthopaedica et traumatologica turcica Pub Date : 2022-07-01 DOI: 10.5152/j.aott.2022.21310
Fang Jie, Zhu Hui, Zheng Dawei, Qi Weiya
{"title":"Treatment of the hook of hamate fracture with robot navigation: A note on technique.","authors":"Fang Jie,&nbsp;Zhu Hui,&nbsp;Zheng Dawei,&nbsp;Qi Weiya","doi":"10.5152/j.aott.2022.21310","DOIUrl":"https://doi.org/10.5152/j.aott.2022.21310","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to demonstrate a new robotic technique for the fixation of the fracture of the hook of hamate.</p><p><strong>Methods: </strong>In this retrospective study, six patients who had undergone treatment of the hook of hamate fracture with a new technique using robot navigation were included. Patients were evaluated postoperatively with flexion - extension and radial-ulnar range of wrist motion, and were measured using a goniometer. Grip strength and pinch strength were measured and compared with the contralateral wrist at the final follow-up. The Visual Analog Scale (VAS) and the Mayo Wrist Score were used to evaluate and record the recovery outcome of the wrist.</p><p><strong>Results: </strong>Primarily, healing was achieved at 12.3 weeks postoperatively. At the final follow-up (5-22 months, average 13.1 months) the VAS score of the wrist was an average of 0.3 (0-2); the mean radial-ulnar deviation was 64.7°; the average of the flexion and extension range of motion was 141.9°; the average grip strength was 40.9 Kg; the average pinch strength was 11.8 Kg and the average Mayo Wrist Score was 95.8.</p><p><strong>Conclusion: </strong>This study has shown us that treatment of nondisplaced or minimal displaced fractures of the hook of the hamate with robot navigation is a viable technique with satisfactory clinical and radiological results.</p>","PeriodicalId":7097,"journal":{"name":"Acta orthopaedica et traumatologica turcica","volume":"56 4","pages":"296-299"},"PeriodicalIF":1.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/aa/63/aott-56-4-296.PMC9612663.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40415646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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