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Acta hepato-gastroenterologica最新文献

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Hepatocellular carcinoma associated with erythrocytosis. A nine year survival after successful chemotherapy and left lateral hepatectomy. 肝细胞癌伴红细胞增多。化疗和左外侧肝切除术成功后9年生存率。
Acta hepato-gastroenterologica Pub Date : 1979-06-01
N Okazaki, H Ozaki, M Arima, N Hattori, K Kimura
{"title":"Hepatocellular carcinoma associated with erythrocytosis. A nine year survival after successful chemotherapy and left lateral hepatectomy.","authors":"N Okazaki,&nbsp;H Ozaki,&nbsp;M Arima,&nbsp;N Hattori,&nbsp;K Kimura","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A case of hepatocellular carcinoma associated with erythrocytosis is described. The patient was successfully treated with a combination chemotherapy of 5-fluorouracil, mitomycin C, cyclophosphamide and chromomycin A3, which was followed by a left lateral hepatectomy, and has survived for more than 9 years after the operation without any signs of recurrence. With the regression of hepatic tumor by the anticancer chemotherapy, the remission of erythrocytosis was observed, indicating that the tumor was producing erythropoietin. The data suggest also that erythrocytosis could be a marker for evaluation of chemotherapeutic effects in some patients with hepatocellular carcinoma.</p>","PeriodicalId":7089,"journal":{"name":"Acta hepato-gastroenterologica","volume":"26 3","pages":"248-52"},"PeriodicalIF":0.0,"publicationDate":"1979-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11441096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diverticular disease of the colon and gallstones in New Zealand and England. 新西兰和英格兰的结肠和胆结石憩室病。
Acta hepato-gastroenterologica Pub Date : 1979-06-01
W M Castleden, K P Jennings, T W Doous, M Leighton
{"title":"Diverticular disease of the colon and gallstones in New Zealand and England.","authors":"W M Castleden,&nbsp;K P Jennings,&nbsp;T W Doous,&nbsp;M Leighton","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The clinical presentation and subsequent treatment of 160 consecutive patients with proven diverticular disease of the colon from the Auckland Hospital, New Zealand were compared with 182 consecutive patients admitted to St. Bartholomew's Hospital, London. There were significant differences in sex incidence, in the ages of the male patients at presentation, patient symptoms, extent of disease and methods of surgical treatment. These probably reflect differences in the types of National Health Services of the two countries, rather than differences in the natural history of diverticular disease of the colon. Overall, the 342 patients studied show a very good correlation with other large series published over the last 10 years. This study confirms the previously reported association between diverticular disease of the colon and gallstones. It confirms that gallstones are more common in female patients with or without diverticular disease. It suggests that Auckland patients with gallstones are more likely to have had a cholecystectomy than London patients. The possible role of dietary fiber in the aetiology of both gallstones and diverticular disease of the colon is discussed.</p>","PeriodicalId":7089,"journal":{"name":"Acta hepato-gastroenterologica","volume":"26 3","pages":"211-6"},"PeriodicalIF":0.0,"publicationDate":"1979-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11690107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abnormal steroid sulfate in plasma of women with intrahepatic cholestasis of pregnancy. 妊娠期肝内胆汁淤积症妇女血浆中硫酸类固醇异常。
Acta hepato-gastroenterologica Pub Date : 1979-06-01
G Giusti, F Piccinino, I Ricciardi, G Delrio, E Sagnelli, G Manzillo
{"title":"Abnormal steroid sulfate in plasma of women with intrahepatic cholestasis of pregnancy.","authors":"G Giusti,&nbsp;F Piccinino,&nbsp;I Ricciardi,&nbsp;G Delrio,&nbsp;E Sagnelli,&nbsp;G Manzillo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Concentrations of numerous sulfate steroids were checked in the plasma of 10 women in normal pregnancy (NP), 21 women with intrahepatic cholestasis of pregnancy (ICP) and 10 pregnant women suffering from viral hepatitis with jaundice (VHP). A considerable increase in 5 alpha pregnane and 5 beta pregnane 3 alpha, 20 alpha diols, mono- and disulfates and in 5 alpha pregnane 3 beta, 20 alpha diols disulfates was observed only in ICP and not in VHP. This observation permits us to hypothesize that these hormone changes can have a causative role in the pathogenesis of ICP.</p>","PeriodicalId":7089,"journal":{"name":"Acta hepato-gastroenterologica","volume":"26 3","pages":"203-6"},"PeriodicalIF":0.0,"publicationDate":"1979-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11687161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gastrin response to insulin in patients with cirrhosis of the liver. 肝硬化患者胃泌素对胰岛素的反应。
Acta hepato-gastroenterologica Pub Date : 1979-06-01
A V Greco, L Altomonte, G Ghirlanda, A G Rebuzzi, R Manna, A Bertoli
{"title":"Gastrin response to insulin in patients with cirrhosis of the liver.","authors":"A V Greco,&nbsp;L Altomonte,&nbsp;G Ghirlanda,&nbsp;A G Rebuzzi,&nbsp;R Manna,&nbsp;A Bertoli","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Fasting gastrinemia in cirrhotics (48.35 +/- 2.77 pg/ml) was higher than in normal controls (32.93 +/- 0.75 pg/ml; P less than 0.001). After insulin-induced hypoglycemia, the mean increase of gastrin above basal level was 42.29 +/- 1.92 pg/ml in controls and 10.85 +/- 5.05 pg/ml in cirrhosis (P less than 0.001). BAO was 2.53 +/- 0.36 mEq/h in controls and 0.42 +/- 0.004 mEq/h in cirrhotics (P less than 0.001). After i.v. insulin, TAO was 8.42 +/- 0.72 mEq/h in controls and 3.06 +/- 0.26 mEq/h in cirrhotics (P less than 0.001). The authors suggest that the lack of an adequate gastrin and acid response to the hypoglycemic stimulus in cirrhotics might be accounted for by a decreased insulin sensitivity.</p>","PeriodicalId":7089,"journal":{"name":"Acta hepato-gastroenterologica","volume":"26 3","pages":"190-4"},"PeriodicalIF":0.0,"publicationDate":"1979-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11592532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changes of serum angiotensin I converting enzyme in patients with viral hepatitis and liver cirrhosis. 病毒性肝炎和肝硬化患者血清血管紧张素I转换酶的变化。
Acta hepato-gastroenterologica Pub Date : 1979-06-01
H Schweisfurth, H Wernze
{"title":"Changes of serum angiotensin I converting enzyme in patients with viral hepatitis and liver cirrhosis.","authors":"H Schweisfurth,&nbsp;H Wernze","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Serum angiotensin I converting enzyme, identical with kininase II, was measured fluorometrically in patients with acute viral hepatitis (n=18), liver cirrhosis without (n=44) and with (n=19) ascites. In all groups of patients the enzyme was significantly elevated as compared to 44 healthy controls (p less than 0.001). No correlation could be found between angiotensin I converting enzyme activity and liver function tests (serum glutamic oxalacetic transaminase, serum glutamic pyruvic transaminase, total protein, albumin, bilirubin) or other parameters (serum potassium, serum sodium). High serum converting enzyme activity in chronic liver diseases might originate primarily from an altered pulmonary circulation and indicates higher conversion rate of angiotensin I by passage through the lungs as well as increased bradykinin degradation. The reason for the enzyme liberation in acute viral hepatitis is as yet uncertain.</p>","PeriodicalId":7089,"journal":{"name":"Acta hepato-gastroenterologica","volume":"26 3","pages":"207-10"},"PeriodicalIF":0.0,"publicationDate":"1979-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11441094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic value of serum bile acids. 血清胆汁酸的诊断价值。
Acta hepato-gastroenterologica Pub Date : 1979-06-01
S Matern, W Gerok
{"title":"Diagnostic value of serum bile acids.","authors":"S Matern,&nbsp;W Gerok","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7089,"journal":{"name":"Acta hepato-gastroenterologica","volume":"26 3","pages":"185-9"},"PeriodicalIF":0.0,"publicationDate":"1979-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11687160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigation of cholecystokinin-octapeptide splitting enzyme in dog kidney. 犬肾中胆囊收缩素-八肽分裂酶的研究。
Acta hepato-gastroenterologica Pub Date : 1979-06-01
J Lonovics, F Hajnal, P Mara, I Szabó, V Varró
{"title":"Investigation of cholecystokinin-octapeptide splitting enzyme in dog kidney.","authors":"J Lonovics,&nbsp;F Hajnal,&nbsp;P Mara,&nbsp;I Szabó,&nbsp;V Varró","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In vitro experiments were carried out to examine the enzymatic activity in various organ homogenates of the dog, which inactivates the biological activity of the synthetic cholecystokinin-octapeptide (CCK-OP). The highest splitting activity was found in the renal cortex; substantially lower activities were registered in the lung, pancreas and small intestine. It seems interesting that neither the gallbladder nor the saliva and the serum contained measurable amount of the CCK-OP splitting activity. An effort was made to characterize the CCK-OP inactivating principle found in the renal cortex. It was ascertained that the CCK-OP was inactivated by a peptidase which is heat sensitive, has a pH optimum of 7,4 and could be inhibited by chelating agents (EDTA) and epsilon-aminocaproic acid. The fact that most of the enzyme function is associated with the sediment obtained at 12 000 g speaks in favour of its mitochondrial origin.</p>","PeriodicalId":7089,"journal":{"name":"Acta hepato-gastroenterologica","volume":"26 3","pages":"222-6"},"PeriodicalIF":0.0,"publicationDate":"1979-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11690109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of gastric distension on human pancreatic secretion. 胃胀对胰分泌的影响。
Acta hepato-gastroenterologica Pub Date : 1979-06-01
J M Cargill, K G Wormsley
{"title":"Effect of gastric distension on human pancreatic secretion.","authors":"J M Cargill,&nbsp;K G Wormsley","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effect of gastric distension on pancreatic secretion of bicarbonate and trypsin was studied in 10 individuals in the basal state or during stimulation with low and high doses of secretin or secretin plus cholecystokinin (CCK). Gastric distension augmented the pancreatic response to secretin but had no consistent effect on the pancreatic response to combination of secretin and CCK. We conclude that gastropancratic reflexes do not have much functional significance in man.</p>","PeriodicalId":7089,"journal":{"name":"Acta hepato-gastroenterologica","volume":"26 3","pages":"235-8"},"PeriodicalIF":0.0,"publicationDate":"1979-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11690113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A review of environmental factors and Crohn's disease. 环境因素与克罗恩病的研究进展。
Acta hepato-gastroenterologica Pub Date : 1979-06-01
J Mayberry
{"title":"A review of environmental factors and Crohn's disease.","authors":"J Mayberry","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7089,"journal":{"name":"Acta hepato-gastroenterologica","volume":"26 3","pages":"257-9"},"PeriodicalIF":0.0,"publicationDate":"1979-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11689057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Alpha-feto protein in the serum of patients with primary gastric cancer and liver metastases. 原发性胃癌及肝转移患者血清中甲胎蛋白的变化。
Acta hepato-gastroenterologica Pub Date : 1979-06-01
E Libman, J Lemberger, J Kollin
{"title":"Alpha-feto protein in the serum of patients with primary gastric cancer and liver metastases.","authors":"E Libman,&nbsp;J Lemberger,&nbsp;J Kollin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors presented a patient with primary gastric cancer and liver metastases. They permanently observed the AFP concentrations before, during and after cytostatic therapy. At the same time they examined possible sites of AFP production. It is supposed that AFP neo-synthesis takes place in the secondary site with participation of altered liver cells. In such cases it is important to watch the AFP values, and this is also necessary when the primary source of the secondary liver cancer is not known. Cytostatic drugs act only in a palliative way i.e. AFP concentrations drop to a lower level and the patient feels temporarily better.</p>","PeriodicalId":7089,"journal":{"name":"Acta hepato-gastroenterologica","volume":"26 3","pages":"198-202"},"PeriodicalIF":0.0,"publicationDate":"1979-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11311044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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