癌症治疗(英文)Pub Date : 2022-01-01DOI: 10.4236/jct.2022.136029
E. Barsoum, Sara El Sherif, M. Ashour, M. Barsoum
{"title":"Follicular Dendritic Cell Sarcoma: A Rare Case Study of Meta-Synchronous Double Primary Cancers Follicular Dendritic Sarcoma and Invasive Breast Cancer","authors":"E. Barsoum, Sara El Sherif, M. Ashour, M. Barsoum","doi":"10.4236/jct.2022.136029","DOIUrl":"https://doi.org/10.4236/jct.2022.136029","url":null,"abstract":"","PeriodicalId":66197,"journal":{"name":"癌症治疗(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70994081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
癌症治疗(英文)Pub Date : 2022-01-01DOI: 10.4236/jct.2022.135024
Sara Anane, A. Ghanam, M. Azizi, A. Bennani, H. Benhaddou, I. Kamaoui, N. Benajiba
{"title":"Pleural Effusion Revealing Bone Ewing Sarcoma: About Three Cases","authors":"Sara Anane, A. Ghanam, M. Azizi, A. Bennani, H. Benhaddou, I. Kamaoui, N. Benajiba","doi":"10.4236/jct.2022.135024","DOIUrl":"https://doi.org/10.4236/jct.2022.135024","url":null,"abstract":"","PeriodicalId":66197,"journal":{"name":"癌症治疗(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70994085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
癌症治疗(英文)Pub Date : 2022-01-01DOI: 10.4236/jct.2022.1312059
Nicola Sarandria
{"title":"A Literature Review in Immuno-Oncology: Pathophysiological and Clinical Features of Colorectal Cancer and the Role of the Doctor-Patient Interaction","authors":"Nicola Sarandria","doi":"10.4236/jct.2022.1312059","DOIUrl":"https://doi.org/10.4236/jct.2022.1312059","url":null,"abstract":"","PeriodicalId":66197,"journal":{"name":"癌症治疗(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70993274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
癌症治疗(英文)Pub Date : 2022-01-01DOI: 10.4236/jct.2022.133014
A. Doumbia, M. Amadou, B. Amadou, S. Zakari, Coulibaly Bourama, Diarra Bourama, T. Adégné
{"title":"Primitive Brelast Lymphoma about a Case: Literature Review","authors":"A. Doumbia, M. Amadou, B. Amadou, S. Zakari, Coulibaly Bourama, Diarra Bourama, T. Adégné","doi":"10.4236/jct.2022.133014","DOIUrl":"https://doi.org/10.4236/jct.2022.133014","url":null,"abstract":"","PeriodicalId":66197,"journal":{"name":"癌症治疗(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70993568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
癌症治疗(英文)Pub Date : 2022-01-01DOI: 10.4236/jct.2022.136028
K. Benali, T. Kebdani, K. Hassouni, S. Majjaoui, H. Kacemi, N. Benjaafar
{"title":"Sarcomatoid Carcinoma of the Mandible: A Case Report and Literature Review","authors":"K. Benali, T. Kebdani, K. Hassouni, S. Majjaoui, H. Kacemi, N. Benjaafar","doi":"10.4236/jct.2022.136028","DOIUrl":"https://doi.org/10.4236/jct.2022.136028","url":null,"abstract":"Background: Sarcomatoid carcinoma is a rare biphasic malignancy with an epithelial and mesenchymal component. Given its histological particularity, the diagnosis of this tumor still represents a challenge for pathologists and surgeons. Sarcomatoid carcinoma of the mandible is a very rare and aggressive entity. To date, only sporadic cases have been reported in the literature. Aim: To report a rare case of aggressive mandibular sarcomatoid carcinoma treated with radical surgery and adjuvant chemoradiation, and discuss the re-lated literature. Case Report: We introduce a rare case of mandibular sarcomatoid carcinoma occurring in a 34-year-old woman. Treatment consisted of radical surgery and re-excision for positive margins, adjuvant radiation therapy (66 Gy in 33 fractions in simultaneous integrated boost delivered using Volumetric Modulated Arc Therapy) and Cisplatin-based concurrent chemotherapy. The tumor displayed aggressive behavior and high metastatic po-tential, causing tumour recurrence and extensive lung metastasis. Conclu-sion: Sarcomatoid carcinoma of the mandible is an extremely rare malignant entity, with a high tendency for local recurrence, distant metastasis. Treatment involves radical surgery and adjuvant chemoradiation, although the outcome and prognosis might be poor.","PeriodicalId":66197,"journal":{"name":"癌症治疗(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70994031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
癌症治疗(英文)Pub Date : 2022-01-01DOI: 10.4236/jct.2022.138045
Manju Domnick, Martin Domnick, I. Ernst, F. Müller, Viktor Rempel, N. Bitterlich, H. Sahinbas, S. Könemann, S. Philippou
{"title":"Observations from the Working Group Peritoneal Carcinosis","authors":"Manju Domnick, Martin Domnick, I. Ernst, F. Müller, Viktor Rempel, N. Bitterlich, H. Sahinbas, S. Könemann, S. Philippou","doi":"10.4236/jct.2022.138045","DOIUrl":"https://doi.org/10.4236/jct.2022.138045","url":null,"abstract":"","PeriodicalId":66197,"journal":{"name":"癌症治疗(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70994714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
癌症治疗(英文)Pub Date : 2022-01-01DOI: 10.4236/jct.2022.137041
Yuru Chen, Jing Feng, Juan Liu, Baochuan Pang, Defa Cao, Cheng Li
{"title":"Detection and Classification of Lung Cancer Cells Using Swin Transformer","authors":"Yuru Chen, Jing Feng, Juan Liu, Baochuan Pang, Defa Cao, Cheng Li","doi":"10.4236/jct.2022.137041","DOIUrl":"https://doi.org/10.4236/jct.2022.137041","url":null,"abstract":"Lung cancer is one of the greatest threats to human health. It is a very effective way to detect lung cancer by pathological pictures of lung cancer cells. Therefore, improving the accuracy and stability of diagnosis is very impor-tant. In this study, we develop an automatic detection scheme for lung cancer cells based on convolutional neural networks and Swin Transformer. Microscopic images of patients’ lung cells are first segmented using a Mask R-CNN-based network, resulting in a separate image for each cell. Part of the background information is preserved by Gaussian blurring of surrounding cells, while the target cells are highlighted. The classification model based on Swin Transformer not only reduces the computation but also achieves better results than the classical CNN model, ResNet50. The final results show that the accuracy of the method proposed in this paper reaches 96.16%. Therefore, this method is helpful for the detection and classification of lung cancer cells.","PeriodicalId":66197,"journal":{"name":"癌症治疗(英文)","volume":"123 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70994743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
癌症治疗(英文)Pub Date : 2022-01-01DOI: 10.4236/jct.2022.139053
Liping Zhang, Qiaoling Zhong, Liling Han, Lijuan Zhang, QingHua Luo, Xinhua Xie, Zeyu Shuang, Na Li
{"title":"Comprehensive Online Management Based on Cloud Platform for Breast Cancer Patients Using Dual-Targeted Therapy with Macromolecular Monoclonal Antibodies","authors":"Liping Zhang, Qiaoling Zhong, Liling Han, Lijuan Zhang, QingHua Luo, Xinhua Xie, Zeyu Shuang, Na Li","doi":"10.4236/jct.2022.139053","DOIUrl":"https://doi.org/10.4236/jct.2022.139053","url":null,"abstract":"","PeriodicalId":66197,"journal":{"name":"癌症治疗(英文)","volume":"80 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70995577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
癌症治疗(英文)Pub Date : 2021-10-15DOI: 10.4236/jct.2021.1210045
T. Shouman, A. N. Taher, A. Helal, Ahmed Charaf
{"title":"Salivary Gland Tumors: Randomized Study of Adjuvant Chemo-Radiotherapy versus Radiotherapy Alone","authors":"T. Shouman, A. N. Taher, A. Helal, Ahmed Charaf","doi":"10.4236/jct.2021.1210045","DOIUrl":"https://doi.org/10.4236/jct.2021.1210045","url":null,"abstract":"Objective: Concurrent chemoradiation value of the resected salivary tumor adjuvant \u0000context against regular radiation therapy alone. Design: Prospective \u0000randomized clinical trial. Patients: 48 patients were randomized to \u0000either adjuvant postoperative radiology alone versus concurrent \u0000chemoradiotherapy (weekly cisplatin 40 mg/m2 for 6 cycles) “with \u0000resected high-risk salivary tumors of the large and minor salivary gland”. Main Outcome Measures: Recurrent locoregional Free survival, distant \u0000free survival, and overall survival. Results: Out of the 48 participants \u0000in the study 31 patients had parotid gland tumors. 23 patients received solely \u0000adjuvant radiation while 25 patients received concurrent chemoradiotherapy. In \u0000the chemoradiation group, platinum-based regimens were employed in all. The mean \u0000age in both groups was 48 years. Adenoid cystic carcinoma was the primary \u0000pathogenic form of both arms 56% (28 cases). Stage II patients were 35% and \u000032%, stage III was 39% and 48% and stage VIa were 26% and 20% in the radiation \u0000arm and chemoradiotherapy arm respectively. 40 of 48 patients (83%) had close \u0000or positive surgical margins and 30 of 48 patients (62%) have a perineural \u0000invasion. Both risk variables are more or less well balanced in both arms with \u0000no statistical difference. The 2- and 4-year estimates of the locoregional \u0000recurrence-free survival rate in the chemoradiation group were 95% and 73%, \u0000compared to 77.4% and 43.6% in the radiation arm respectively (p = 007). In the \u0000two-and four-year-old chemoradiation arm distant free metastases were 100% and \u000059% compared to 68% and 39% respectively in the radiation arm (p = 0.08). The \u0000overall survival estimates for 2 and 4 years were 93% and 78% respectively in \u0000the Chemoradiation Group but in the radiation-alone group were 95% and 48% \u0000respectively. The statistically significant differences were p = 0.009 by \u0000log-rank testing. Treatment was generally tolerated, although, in the \u0000chemoradiation group adverse symptoms, mainly mucositis increased. Conclusions: Adding weekly cisplatin as a radiosensitizer for locally advanced stage or \u0000high-grade salivary gland cancer with adjuvant conventional radiation looks to \u0000be helpful and justifies further exploration in selected patients.","PeriodicalId":66197,"journal":{"name":"癌症治疗(英文)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42010666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
癌症治疗(英文)Pub Date : 2021-09-07DOI: 10.4236/jct.2021.129043
Mayson A. Alameen, A. Ibrahim, Touqeer Ahmed Siddiqui, Mervat Mohrous, Fadhel Alotaibi, Abdel Aziz Al Hamad, Hussein Farghaly
{"title":"Primary Isolated Extra Nodal Esophageal Hodgkin Lymphoma in Diabetic Patient","authors":"Mayson A. Alameen, A. Ibrahim, Touqeer Ahmed Siddiqui, Mervat Mohrous, Fadhel Alotaibi, Abdel Aziz Al Hamad, Hussein Farghaly","doi":"10.4236/jct.2021.129043","DOIUrl":"https://doi.org/10.4236/jct.2021.129043","url":null,"abstract":"Primary \u0000isolated esophageal Hodgkin’s lymphoma is seldom in localization and when seen, it is usually the non-Hodgkin’s \u0000type. We reported a 68-year-old, diabetic and ex-smoker, presented to \u0000our hospital complaining of progressive difficulty of swallowing for nine months for both solid and liquid. \u0000He was on proton pump inhibitors. Recently, he had fever and drenching night sweat and significant loss of weight. He was diagnosed as a case of isolated esophageal \u0000Hodgkin’s lymphoma that was diagnosed based on endoscopic and radiological findings. Clinical \u0000manifestations, radiological imagines and histopathological features were \u0000described. Clinical management, fellow-up and outcome were precisely discussed.","PeriodicalId":66197,"journal":{"name":"癌症治疗(英文)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43079985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}