现代医药卫生最新文献

{"title":"Comparative analysis of detection performance of novel coronavirus nucleic acid detection reagents.","authors":"何绍平 姜亚运 袁成良 刘冬冬","doi":"10.3969/j.issn.1009-5519.2021.17.008","DOIUrl":"https://doi.org/10.3969/j.issn.1009-5519.2021.17.008","url":null,"abstract":"Objective To evaluate the detection performance of novel coronavirus nucleic acid reagents (Maccura Biological Co.,Ltd,fluorescent PCR method),it is validated clinically and used the same kinds of kits for comparsion research.Methods Compared with novel coronavirus nucleic acid reagents (Shanghai Zhijiang Biological Co.,Ltd,fluorescent PCR method),the similar products of Maccura Biological Co.,Ltd was to be estimated.Pharyngeal swab specimens of 14 COVID-19 patients diagnosed by the CDC and 211 general admission patients from February 18 to 24 were taken into our study,and two kits were used for parallel testing novel coronavirus (ORF1ab/N/E gene).Results The positive rate and negative coincidence rate of Maccura detection kit and Zhijiang' were more than 99.5%.Relative deviation of ORF1ab gene and N gene were not more than ±16%.Conclusion Novel coronavirus nucleic acid detection reagents produced by Maccura Biological Co.,Ltd has good consistency with similar reagents approved for marketing,which can meet the needs of clinical testing. (English) [ABSTRACT FROM AUTHOR] 目的 对迈克生物股份有限公司的新型冠状病毒核酸试剂盒(荧光PCR法)进行临床验证,并 用同类试剂盒进行比对研究。方法 以迈克生物股份有限公司的研发生产的新型冠状病毒核酸检测试剂盒 (荧光PCR法)作为待考核试剂,以上海之江生物科技有限公司的同类产品作为比对试剂。分别对14例由疾控 中心确诊的新型冠状病毒肺炎患者和2020年2月18日至2月24日211例普通入院患者的咽拭子标本进行新 型冠状病毒(ORF1ab/N/E基因)检测,比较两种试剂检测检出率的一致性。结果 迈克新型冠状病毒核酸检 测试剂盒与之江新型冠状病毒核酸检测试剂盒的检测结果阳性率和阴性符合率均达99.5%以上,ORF1ab基 因和N 基因测定值相对偏差不超过±16%。结论 迈克新型冠状病毒核酸检测试剂盒与已获批准上市的同类 试剂检测结果一致性良好,可满足临床检测需求。 (Chinese) [ABSTRACT FROM AUTHOR] Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)","PeriodicalId":64416,"journal":{"name":"现代医药卫生","volume":"37 1","pages":"2909-2911"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70180689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of relationship between asthenopia and terminal screen exposure in college students during COVID-19 epidemic period.","authors":"陈伟 陈道俊 程钊 张夏雨 刘茂洁 曹雅雯","doi":"10.3969/j.issn.1009-5519.2021.15.002","DOIUrl":"https://doi.org/10.3969/j.issn.1009-5519.2021.15.002","url":null,"abstract":"Objective To understand the relationship between the visual fatigue of college students and the exposure of terminal screens during the novel coronavirus pneumonia (New Coronary Pneumonia) epidemic. Methods The cluster sampling method of the current situation survey was adopted. From March 1 to July 1, 2020, a questionnaire survey of 2671 college students in Hefei City, Anhui Province was conducted to analyze the eye discomfort, daily eye use and eye care of college students during the new coronary pneumonia epidemic. Situation and so on. Results Among the 2 671 college students, 1 860 cases were positive for asthenopia, with a total positive rate of 69.64%. Eye fatigue [5646% (1508/2671)], dry eyes [46.01% (1 229/2 671)], eye swelling [ The incidence of 38.26% (1022/2671)], eye itching and pain [28.15% (752/2 671)] ranked the top 4. Lunch break habits and the number of drinking glasses per day are common protective factors for eye fatigue, dry eyes, sore eyes, and itchy eyes;closing doors and windows during online classes and staying up late each week are common risks for eye fatigue, dry eyes, and sore eyes Factors;daytime terminal screen exposure time is a common risk factor for dry eyes, sore eyes, and itchy eyes. Conclusion During the new crown pneumonia epidemic, the incidence of visual fatigue among college students is relatively high. Terminal screen exposure is one of the risk factors for visual fatigue. Reducing the exposure time of college students to terminal screens is an effective measure to prevent visual fatigue. (English) [ABSTRACT FROM AUTHOR] 目的了解新型冠状病毒肺炎(简称新冠肺炎)疫情期间大学生视疲劳与终端屏幕暴露的关 联。方法采用现况调查整群抽样方法,2020 年3月1日至7月1日通过问卷调查安徽省合肥市高校的2671 名大学生,分析新冠肺炎疫情期间大学生眼部不适､日常用眼及护眼情况等。结果 2 671 名大学生中视疲劳 阳性 1 860 例,总阳性率为69.64%,眼疲劳感[5646%(1508/2671)]､眼干涩[46.01%(1 229/2 671)]､眼酸 胀[38.26%(1022/2671)]、眼痒痛[28.15%(752/2 671)]发生率排前4位。午休习惯和每天饮水杯数是眼疲 劳感､眼干涩､眼酸胀､眼痒痛的共同保护因素;上网课时关闭门窗和每周熬夜次数是眼疲劳感､眼干涩､眼酸胀 的共同危险因素;白天终端屏幕暴露时间是眼干涩､眼酸胀､眼痒痛的共同危险因素。结论 新冠肺炎疫情期 间大学生视疲劳发生率较高,终端屏幕暴露是视疲劳的危险因素之一,降低大学生对终端屏幕暴露时间是预防 視疲劳的有效措施. (Chinese) [ABSTRACT FROM AUTHOR] Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)","PeriodicalId":64416,"journal":{"name":"现代医药卫生","volume":"37 1","pages":"2523-2527"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70180733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis on clinical characteristics and prognosis in 248 cases of COVID-19 in Chongqing city.","authors":"卢花 熊芳 刘超 潘鸡飞 周岐龙","doi":"10.3969/j.issn.1009-5519.2021.15.010","DOIUrl":"https://doi.org/10.3969/j.issn.1009-5519.2021.15.010","url":null,"abstract":"Objective To explore and analyze the clinical characteristics and prognosis of 248 patients with novel coronavirus pneumonia (COVID-19) in Chongqing, so as to provide reference for clinical diagnosis and treatment of COVID-19. Methods The clinical data of 248 patients with COV ID-19 admitted to the hospital from January 21 to March 11, 2020 were retrospectively analyzed, including 195 patients in the non-severe group (mild type/normal type) and the severe group (severe type/critical type). Type) 53 cases. Comparing the general conditions, clinical manifestations, laboratory test results and prognosis of the two groups of patients, the average age of 248 patients was (47.69±15.59) years old. Adults accounted for 97.6% (242/248), men were slightly more than women (54.0% (134/248), 46.0% (114/248), respectively), hospitalization time was 14.00 (12.00, 22,000 days. The fatality rate was 16% ( 4/248), the fatality rate of patients in the severe group was 7.5% (4/53). After the cured patients were discharged from the hospital, 4 patients in the non-critical group were followed up for reimpedance, and there was no evidence of infecting others. The age of the severe group patients, as well as diabetes and chronic obstruction The proportions of pulmonary disease, coronary heart disease, malignant tumors, cough, sputum, shortness of breath, dyspnea, and fatigue are all significantly higher than those of the non-severe group. The counts of lymphocytes, monocytes, lymphocytes, total T lymphocytes, Helper/inducible T lymphocytes, inhibitory/cytotoxic T lymphocytes, B lymphocytes, and natural killer cells are significantly lower than the non-severe group, neutrophils, urea nitrogen, direct bilirubin, aspartate aminotransferase, prothrombin time, Partially activated prothrombin time, D-dimer. C-reactive protein, procalcitonin, and interleukin-6 were significantly higher than those in the non-critical group, and the differences were statistically significant (P<0.05). Conclusions Elderly Patients with diabetes mellitus, chronic obstructive pulmonary disease, coronary heart disease, malignant tumors and other diseases are more likely to progress to severe cases. Clinical medical advancement combines patient symptoms and related laboratory test results to identify critically ill patients early and admit them to the intensive care unit for enhanced monitoring and treatment. Reduce the fatality rate of COVID 19 patients. (English) [ABSTRACT FROM AUTHOR] 目的探讨并分析重庆市 248 例新型冠状病毒肺炎(COVID-19)患者的临床特征和预后,为临 床诊疗 COVID-19 提供参考依据。方法回顾性分析2020年1月21日至3月11日该院收治的248例COV ID-19 患者的临床资料,其中非重症组(轻微型/普通型)195例,重症组(重型/危重型)53例。比较2组患者一 般情况､临床表现、实验室检验结果及预后等,结果 248例患者平均年龄(47.69±15.59)岁。成人占97.6% (242/248),男性稍多于女性[分别为54.0%(134/248)、46.0%(114/248)],住院时间 14.00 (12.00,22,000d. 病死率为16%(4/248),重症组患者病死率为7.5%(4/53),治愈患者出院后随访4例非重症组患者复阻,无传 染他人的证据,重症组患者年龄,以及合并糖尿病、慢性阻塞性肺疾病､冠心病、恶性肿瘤比例,出现咳嗽、咳 痰､气促、呼吸困难、乏力比例均明显高于非重症组,入院时淋巴细胞、单核细胞 淋巴细胞计数､总T淋巴细胞、 辅助/诱导T淋巴细胞､抑制/细胞毒T淋巴细胞、B淋巴细胞、自然杀伤细胞均明显低于非重症组,中性粒细 胞､尿素氮､直接胆红素､谷草","PeriodicalId":64416,"journal":{"name":"现代医药卫生","volume":"12 1","pages":"2559-2564"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70180550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Status quo and correlation study of sleep quality and social support of frontline medical workers fighting COVID-19 in Wuhan.","authors":"顾 婕 吴 菁 丁 艳 曹 洁 谢明晖","doi":"10.3969/j.issn.1009-5519.2021.17.011","DOIUrl":"https://doi.org/10.3969/j.issn.1009-5519.2021.17.011","url":null,"abstract":"Objective To understand the status quo of sleep quality and social support of medical staffs in Wuhan who fighting against the epidemic of novel coronavirus pneumonia(COVID-19),and explore the relationship between them. Methods A total of 135 medical staffs were investigated by the cluster sampling method. The Pittsburgh sleep quality index (PSQI),social support rating scale(SSRS) and self-designed demographic information questionnaire were used to investigate the 135 first-line medical staffs. Results The total score of social support was (41. 85 ± 7. 76 ) scores, the highest score was subjective social support [(22. 87±3. 99)scores],and the lowest was utilization [(7. 92 ±2. 04)scores];the total score of sleep quality was (8. 12±4. 17)scores, the highest score was sleep time [(1. 72±0. 92)scores], and the lowest was hypnotic drug [(O. 41± 0. 84) scores]. The total score of SSRS was negatively correlated with sleep quality in PSQI (r = —0. 222,P <0. 05) ;the two dimensions of subjective social support and utilization in SSRS,and the total score of SSRS were positively correlated with daytime dysfunction in PSQI (r = 0. 245, O. 244, 0.279, P< 0. 05), the total score of PSQI was negatively correlated with utilization in SSRS (r = — 0. 234, P <0. 05). Conclusion Social support of the medical staffs in Wuhan has an impact on their sleep quality. (English) [ABSTRACT FROM AUTHOR] 目的 了解武汉抗疫一线医护人员睡眠质量和社会支持的现状并探索两者之间的关系。方法 采用整群抽样法,应用匹兹堡睡眠指数量表(PSQI)、社会支持量表(SSRS)、自制一般情况调查表对135名抗 击新型冠状病毒肺炎(COVID-19)的临床一线医护人员的睡眠质量进行调查。结果 武汉抗疫一线医护人员 社会支持总分为(41.85±7.76)分,各维度中得分最高的是主观社会支持[(22.87±3.99)分],最低的是利用度 [(7.92±2.04)分];睡眠质量总分为(8.12±4.17)分,各维度中得分最高的是睡眠时间[(1.72±0.92)分],最 低的是催眠药物[(0.41±0.84)分]。SSRS总分与PSQI中的睡眠质量维度呈显著负相关(r=-0.222,P < 0.05);SSRS中的主观社会支持、利用度等2个维度及SSRS总分与PSQI中的日间功能障碍维度呈显著正相 关(r=0.245、0.244、0.279,P <0.05),PSQI总分与SSRS的利用度维度呈显著负相关(r=-0.234,P < 0.05)。结论 武汉抗疫一线医护人员的社会支持对其睡眠质量有影响。 (Chinese) [ABSTRACT FROM AUTHOR] Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)","PeriodicalId":64416,"journal":{"name":"现代医药卫生","volume":"62 1","pages":"2921-2925"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70180761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of the psychological state and influencing factors of college students returning to Guangzhou University City during the outbreak of COVID-19.","authors":"元 杨燕君 吴少敏 唐","doi":"10.3969/j.issn.1009-5519.2021.20.006","DOIUrl":"https://doi.org/10.3969/j.issn.1009-5519.2021.20.006","url":null,"abstract":"Objective To investigate the knowledge awareness and psychological status of college students returning to school during the outbreak of COVID-19,analyze the relevant influencing factors,and provide reference for the formulation of psychological intervention measures.Methods From May 14 to 17, 2020,a questionnaire survey was conducted on the 728 students which approved return ingress of a medical university in Guangdong University using the Psychological Questionnaire for Sudden Public Health Events (PQEEPH) and analyzed by SPSS19.0 software.Results A total of 728 university students were approved for returning to school,of whom 33.24%(242/728) were boys,66.76%(486/728) were women,60.30% (439/728) were in undergraduate studies and 39.70%(289/728) were in graduate school.The six aspects of personal preventive measures for COVID-19 accounted for 97.8%,Only 9.89%t of patients with COVID-19 were known to have the three main manifestations.The dimension scored by the PQEEPH scale from high to low:fear [(1.75±0.51)scores],nervous breakdown [(1.34±0.44)scores],depression [(1.28±0.42) scores],suspect [(1.25±0.39)scores],compulsion-anxiety [(1.13±0.30)scores];Relatively heavy;those who did not return to school and did not determine the time of return were more likely to be ill;those who lived with a family generally or poorly,who did not know whether the community where they lived had found new crown cases,had a higher level of depression,nervous breakdown,compulsive-anxiety;depression,nervous breakdown,fear,compulsion anxiety and suspecting were relatively severe in the five dimensions of those who expressed difficulty in controlling their emotions and those who expressed stress and anxiety.Conclusion The college students who have been approved to return to school lack a comprehensive grasp of the knowledge of COVID-19,and their psychological state is influenced by many factors,and should formulate targeted educational and psychological interventions to improve the knowledge of COVID-19,reduce or even avoid the occurrence of bad emotions. (English) [ABSTRACT FROM AUTHOR] 目的 调查新型冠状病毒肺炎(COVID-19)疫情期间返校大学生COVID-19相关知识知晓与 心理状况,分析相关影响因素,为制定心理干预措施提供参考。方法 2020年5月14-17日采用突发性公共 卫生事件心理问卷(PQEEPH)对广州某医科大学已批准返校的728名大学生进行问卷调查,采用SPSS19.0统 计软件进行分析。结果 728名大学生中男生占33.24%(242/728),女生占66.76%(486/728);在读本科生占 60.30%(439/728),在读硕士研究生占39.70%(289/728)。知晓COVID-19个人预防措施的6个方面内容者 占97.8%,知晓COVID-19患者的3个主要表现者仅占9.89%。突发性公共卫生事件心理问卷各维度评分由 高至低依次为恐惧[(1.75±0.51)分]、神经衰弱[(1.34±0.44)分]、抑郁[(1.28±0.42)分]、疑病[(1.25± 0.39)分]、强迫-焦虑[(1.13±0.30)分]。未返校且未确定返校时间者疑病状况较重;与一同居住的家人关系一 般或较差者、不知道所居住小区是否发现过COVID-19病例者抑郁、神经衰弱、强迫-焦虑状况较重;表示控制自 己情绪非常困难者和表示生活状态为紧张担心者抑郁、神经衰弱、恐惧、强迫焦虑、疑病5个维度的状况均相对 较重。结论 返校大学生对COVID-19相关知识缺乏全面掌握,其心理状态受多方面因素的影响,应制定针对 性宣教与心理干预措施,在提高COVID-19相关知识知晓率的同时降低不良情绪发生率。 (Chinese) [ABSTRACT FROM AUTHOR] Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without t","PeriodicalId":64416,"journal":{"name":"现代医药卫生","volume":"37 1","pages":"3438-3447"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70181100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}