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枫蓼提取物的抗炎作用及机制研究 枫蓼提取物的抗炎作用及机制研究
中药药理与临床 Pub Date : 2016-02-15 DOI: 10.13412/j.cnki.zyyl.2016.01.045
任守忠 | 苏文琴 | 陈君 | 王宁 | 林紫薇 | 何瑞 | 王辉
{"title":"枫蓼提取物的抗炎作用及机制研究","authors":"任守忠 | 苏文琴 | 陈君 | 王宁 | 林紫薇 | 何瑞 | 王辉","doi":"10.13412/j.cnki.zyyl.2016.01.045","DOIUrl":"https://doi.org/10.13412/j.cnki.zyyl.2016.01.045","url":null,"abstract":"","PeriodicalId":62298,"journal":{"name":"中药药理与临床","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142042180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
黄芪多糖对肺癌微环境中BMSCs增殖及TAFs分化的影响 黄芪多糖对肺癌微环境中BMSCs增殖及TAFs分化的影响
Pub Date : 2015-12-15 DOI: 10.13412/j.cnki.zyyl.2015.06.023
武有明 | 张齐 | 刘永琦 | 何建新 | 伍志伟 | 高卓越 | 苏韫 | 骆亚莉 | 张利英 | 周妮娜
{"title":"黄芪多糖对肺癌微环境中BMSCs增殖及TAFs分化的影响","authors":"武有明 | 张齐 | 刘永琦 | 何建新 | 伍志伟 | 高卓越 | 苏韫 | 骆亚莉 | 张利英 | 周妮娜","doi":"10.13412/j.cnki.zyyl.2015.06.023","DOIUrl":"https://doi.org/10.13412/j.cnki.zyyl.2015.06.023","url":null,"abstract":"","PeriodicalId":62298,"journal":{"name":"","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2015-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142042020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
贝母辛对LPS致黏液高分泌小鼠MUC5AC和EGFR表达的影响 贝母辛对LPS致黏液高分泌小鼠MUC5AC和EGFR表达的影响
中药药理与临床 Pub Date : 2015-06-15 DOI: 10.13412/j.cnki.zyyl.2015.03.006
崔艳茹 | 刘海云 | 屈飞
{"title":"贝母辛对LPS致黏液高分泌小鼠MUC5AC和EGFR表达的影响","authors":"崔艳茹 | 刘海云 | 屈飞","doi":"10.13412/j.cnki.zyyl.2015.03.006","DOIUrl":"https://doi.org/10.13412/j.cnki.zyyl.2015.03.006","url":null,"abstract":"","PeriodicalId":62298,"journal":{"name":"中药药理与临床","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2015-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142042104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
威灵仙总皂苷对佐剂性关节炎(AA)大鼠IL-6、IL-10及滑膜中p-JAK2、p-STAT3表达的影响 威灵仙总皂苷对佐剂性关节炎(AA)大鼠IL-6、IL-10及滑膜中p-JAK2、p-STAT3表达的影响
中药药理与临床 Pub Date : 2015-02-15 DOI: 10.13412/j.cnki.zyyl.2015.01.028
汪永忠 | 邓龙飞 | 韩燕全 | 姜辉 | 李钰馨
{"title":"威灵仙总皂苷对佐剂性关节炎(AA)大鼠IL-6、IL-10及滑膜中p-JAK2、p-STAT3表达的影响","authors":"汪永忠 | 邓龙飞 | 韩燕全 | 姜辉 | 李钰馨","doi":"10.13412/j.cnki.zyyl.2015.01.028","DOIUrl":"https://doi.org/10.13412/j.cnki.zyyl.2015.01.028","url":null,"abstract":"","PeriodicalId":62298,"journal":{"name":"中药药理与临床","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2015-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142042075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
当归挥发油对大鼠十二指肠慢波肌电活动的作用研究 当归挥发油对大鼠十二指肠慢波肌电活动的作用研究
中药药理与临床 Pub Date : 2014-12-15 DOI: 10.13412/j.cnki.zyyl.2014.06.021
高云娟 | 吴迪 | 吴国泰 | 杜丽东 | 李应东 | 文晓玲 | 任远
{"title":"当归挥发油对大鼠十二指肠慢波肌电活动的作用研究","authors":"高云娟 | 吴迪 | 吴国泰 | 杜丽东 | 李应东 | 文晓玲 | 任远","doi":"10.13412/j.cnki.zyyl.2014.06.021","DOIUrl":"https://doi.org/10.13412/j.cnki.zyyl.2014.06.021","url":null,"abstract":"","PeriodicalId":62298,"journal":{"name":"中药药理与临床","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2014-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142039178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
胶球藻多糖对大鼠脑缺血再灌注损伤的保护作用 胶球藻多糖对大鼠脑缺血再灌注损伤的保护作用
Pub Date : 2014-12-15 DOI: 10.13412/j.cnki.zyyl.2014.06.036
隋海娟 | 张玲玲 | 金英
{"title":"胶球藻多糖对大鼠脑缺血再灌注损伤的保护作用","authors":"隋海娟 | 张玲玲 | 金英","doi":"10.13412/j.cnki.zyyl.2014.06.036","DOIUrl":"https://doi.org/10.13412/j.cnki.zyyl.2014.06.036","url":null,"abstract":"","PeriodicalId":62298,"journal":{"name":"","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2014-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142039890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
虫草素抑制脂多糖诱导气道上皮细胞损伤作用机制研究 虫草素抑制脂多糖诱导气道上皮细胞损伤作用机制研究
Pub Date : 2014-08-15 DOI: 10.13412/j.cnki.zyyl.2014.04.014
张天柱 | 吴国梁 | 杨世海 | 姚文斌 | 程潜
{"title":"虫草素抑制脂多糖诱导气道上皮细胞损伤作用机制研究","authors":"张天柱 | 吴国梁 | 杨世海 | 姚文斌 | 程潜","doi":"10.13412/j.cnki.zyyl.2014.04.014","DOIUrl":"https://doi.org/10.13412/j.cnki.zyyl.2014.04.014","url":null,"abstract":"","PeriodicalId":62298,"journal":{"name":"","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2014-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142040014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Protective effect of baicalin against rotenone induced injury on PC12 cells 黄芩苷对鱼藤酮诱导的PC12细胞损伤的保护作用
Pub Date : 2014-08-01 DOI: 10.4268/cjcmm20141529
Hai-Lie Ji, Li-Guo Tong, Chongzhi Bai, Mei-Qing Song, Naihong Chen, Ma-Li Feng
{"title":"Protective effect of baicalin against rotenone induced injury on PC12 cells","authors":"Hai-Lie Ji, Li-Guo Tong, Chongzhi Bai, Mei-Qing Song, Naihong Chen, Ma-Li Feng","doi":"10.4268/cjcmm20141529","DOIUrl":"https://doi.org/10.4268/cjcmm20141529","url":null,"abstract":"OBJECTIVE: To explore the protective effect of baicalin against rotenone-induced injury on PC12 cells, and the po-tential mechanism of action action was also explored. METHOD: PC12 cells were injured by rotenone and were treated with different concentrations (0.1, 1, 10 μmol x L(-1)) of baicalin at the same time. Cell viability was analyzed by MTT, and morphology was observed by phase-contrast microscopy. The cell apoptosis was detected by flow cytometry by Annexin V-FITC/PI staining. The intracellular ROS level was determined by fluorescence microscope with DCF-DA staining. The expression of Bcl-2, Bax and Caspase-3 was analyzed by Western blot. RESULT: The viability of PC12 cells exposure to rotenone for 24 hour was gradually decreased with dose escalating and 1.5 μmol x L was adopted to do the following experiment. Baicalin increased cell viability, improved cell morphology and decreased intracellular ROS level. Moreover, FACS indicated baicalin attenuated the apoptosis induced by rotenone significantly. Western blot showed that Bcl-2, Bax and Caspase-3 expression in rotenone-induced PC12 cells was reversed by baicalin. CONCLUSION: This study has demonstrated that baicalin protects PC12 cells against rotenone-induced apoptosis, at least in part, by scavenging excessive ROS and inhibiting the mitochondrion-dependent apoptotic pathway.","PeriodicalId":62298,"journal":{"name":"","volume":"39 15","pages":"2947-51"},"PeriodicalIF":0.0,"publicationDate":"2014-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147922544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
马钱苷、莫诺苷对AGEs损伤HUVEC的增殖的影响 马钱苷、莫诺苷对AGEs损伤HUVEC的增殖的影响
Pub Date : 2014-06-15 DOI: 10.13412/j.cnki.zyyl.2014.03.017
刘凯 | 许惠琴 | 吴佳蕾 | 陆春红 | 吕兴 | 吴云皓 | 周芷若
{"title":"马钱苷、莫诺苷对AGEs损伤HUVEC的增殖的影响","authors":"刘凯 | 许惠琴 | 吴佳蕾 | 陆春红 | 吕兴 | 吴云皓 | 周芷若","doi":"10.13412/j.cnki.zyyl.2014.03.017","DOIUrl":"https://doi.org/10.13412/j.cnki.zyyl.2014.03.017","url":null,"abstract":"","PeriodicalId":62298,"journal":{"name":"","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2014-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142041908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
血塞通软胶囊对家兔眼球微循环障碍及血瘀大鼠血液流变性的影响 血塞通软胶囊对家兔眼球微循环障碍及血瘀大鼠血液流变性的影响
Pub Date : 2014-02-15 DOI: 10.13412/j.cnki.zyyl.2014.01.020
郭沛鑫 | 刘承明
{"title":"血塞通软胶囊对家兔眼球微循环障碍及血瘀大鼠血液流变性的影响","authors":"郭沛鑫 | 刘承明","doi":"10.13412/j.cnki.zyyl.2014.01.020","DOIUrl":"https://doi.org/10.13412/j.cnki.zyyl.2014.01.020","url":null,"abstract":"","PeriodicalId":62298,"journal":{"name":"","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2014-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142039054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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