发布求助
文献互助 智能选刊 最新文献

中华临床医药与护理最新文献

筛选
英文 中文
脂肪微环境对乳腺癌代谢重塑的影响 脂肪微环境对乳腺癌代谢重塑的影响
中华临床医药与护理 Pub Date : 2025-12-01 DOI: 10.63887/cn.2025.1.8.8
方娜娜
{"title":"脂肪微环境对乳腺癌代谢重塑的影响","authors":"方娜娜","doi":"10.63887/cn.2025.1.8.8","DOIUrl":"https://doi.org/10.63887/cn.2025.1.8.8","url":null,"abstract":"乳腺癌被认为是最常见的恶性肿瘤，具有广泛的代谢重编程能力。在乳腺癌微环境中，与癌症高度相关的脂肪细胞通过释放各种脂肪细胞因子和代谢物，与乳腺癌细胞相互作用，乳腺癌微环境中脂肪细胞的积累与乳腺癌增加的发病率、恶化和转移有关。乳腺癌细胞与功能失调的脂肪细胞之间的相互作用引起的乳腺癌的代谢变化，包括葡萄糖、脂质和氨基酸代谢。因此，阻止乳腺癌细胞与功能失调的脂肪组织之间的相互作用可能会成为一种很有前景的乳腺癌治疗策略。本综述重点探讨了乳腺癌细胞与脂肪细胞之间相互作用，以及脂肪微环境介导乳腺癌糖代谢和脂质代谢变化。此外还回顾了旨在破坏这种相互作用的治疗学的最新进展。","PeriodicalId":61242,"journal":{"name":"中华临床医药与护理","volume":"1 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sci-open.net/index.php/CN/article/download/5972/7497","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147897701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
丁二磺酸腺苷蛋氨酸联合熊去氧胆酸对妊娠期肝内胆汁淤积症患者胆汁酸水平的影响 丁二磺酸腺苷蛋氨酸联合熊去氧胆酸对妊娠期肝内胆汁淤积症患者胆汁酸水平的影响
中华临床医药与护理 Pub Date : 2025-11-10 DOI: 10.63887/cn.2025.1.7.12
曾足娥, 李娜, 左媛
{"title":"丁二磺酸腺苷蛋氨酸联合熊去氧胆酸对妊娠期肝内胆汁淤积症患者胆汁酸水平的影响","authors":"曾足娥, 李娜, 左媛","doi":"10.63887/cn.2025.1.7.12","DOIUrl":"https://doi.org/10.63887/cn.2025.1.7.12","url":null,"abstract":"探讨熊去氧胆酸联合丁二磺酸腺苷蛋氨酸治疗妊娠期肝内胆汁淤积症对胆汁酸水平的影响。方法：选取2023年5月至2025年4月收治的62例患者，随机分为两组，对照组（n=31）采用单纯熊去氧胆酸治疗和31例观察组（执行熊去氧胆酸+丁二磺酸腺苷蛋氨酸联合治疗方案），比较治疗效果。结果 观察组治疗总有效率96.77%，对照组治疗总有效率77.42%（P","PeriodicalId":61242,"journal":{"name":"中华临床医药与护理","volume":"1 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sci-open.net/index.php/CN/article/download/5074/6629","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147881790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
站桩对2型糖尿病患者血糖、血脂及心理状态的综合影响 站桩对2型糖尿病患者血糖、血脂及心理状态的综合影响
中华临床医药与护理 Pub Date : 2025-11-10 DOI: 10.63887/cn.2025.1.7.17
王伟
{"title":"站桩对2型糖尿病患者血糖、血脂及心理状态的综合影响","authors":"王伟","doi":"10.63887/cn.2025.1.7.17","DOIUrl":"https://doi.org/10.63887/cn.2025.1.7.17","url":null,"abstract":"2型糖尿病作为一种代谢性慢性疾病，常伴随血糖、血脂紊乱及心理问题，严重影响患者生活质量。近年来，传统养生功法——站桩，因其身心兼修的特性，在慢病干预中备受关注。本文基于实证调查和文献分析，探讨站桩训练对2型糖尿病患者血糖、血脂水平及心理状态的综合影响机制。研究发现，站桩有助于改善代谢指标，调节神经内分泌系统，缓解焦虑抑郁等负面情绪，体现出较好的非药物干预价值。文章提出，将其纳入糖尿病康复方案中，有助于实现医体融合与身心协同调养的目标。","PeriodicalId":61242,"journal":{"name":"中华临床医药与护理","volume":"1 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sci-open.net/index.php/CN/article/download/5079/6634","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147884478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
培菲康联合美沙拉嗪对溃疡性结肠炎患者临床疗效观察 培菲康联合美沙拉嗪对溃疡性结肠炎患者临床疗效观察
中华临床医药与护理 Pub Date : 2025-11-10 DOI: 10.63887/cn.2025.1.7.18
于京芳, 李帅, 谭杰, 江学良
{"title":"培菲康联合美沙拉嗪对溃疡性结肠炎患者临床疗效观察","authors":"于京芳, 李帅, 谭杰, 江学良","doi":"10.63887/cn.2025.1.7.18","DOIUrl":"https://doi.org/10.63887/cn.2025.1.7.18","url":null,"abstract":"验证培菲康联合美沙拉嗪治疗溃疡性结肠炎的临床有效性和安全性，并为粪便钙卫蛋白的临床应用提供临床依据。方法：本研究将符合纳排标准的60例患者随机分为对照组（美沙拉嗪4g/日）、治疗组（美沙拉嗪4g/日+双歧杆菌三联活菌(培菲康）0.84g/日），疗程8周。运用SPSS27.0统计学软件分析治疗前后两组患者粪便钙卫蛋白含量、实验室指标等变化。结果：1.培菲康联合美沙拉嗪治疗可以降低溃疡性结肠炎患者粪便钙卫蛋白含量，差异有统计学意义（P＜0.05）。2.培菲康联合美沙拉嗪治疗可以降低C反应蛋白含量减轻炎症反应，但差异无统计学意义（P＞0.05）。3.培菲康联合美沙拉嗪治疗可以提高白蛋白含量改善患者营养状况，治疗组差异有统计学意义（组内P＜0.05）。结论：培菲康联合美沙拉嗪治疗对溃疡性结肠炎患者临床安全有效，可降低粪便钙卫蛋白含量，减轻炎症反应，改善患者营养状况。","PeriodicalId":61242,"journal":{"name":"中华临床医药与护理","volume":"1 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sci-open.net/index.php/CN/article/download/5080/6636","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147890378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
基于“虚热瘀”理论辨治绝经后骨质疏松症 基于“虚热瘀”理论辨治绝经后骨质疏松症
中华临床医药与护理 Pub Date : 2025-10-20 DOI: 10.63887/cn.2025.1.6.23
熊传发, 梁洪
{"title":"基于“虚热瘀”理论辨治绝经后骨质疏松症","authors":"熊传发, 梁洪","doi":"10.63887/cn.2025.1.6.23","DOIUrl":"https://doi.org/10.63887/cn.2025.1.6.23","url":null,"abstract":"绝经后骨质疏松症是指女性卵巢功能衰退、雌激素水平降低的一种高转化型代谢性骨疾病，由于功能衰退、雌激素缺乏导致骨量减少及骨微小结构破坏，使骨脆性增多易于骨折，以及由骨折引起的疼痛、骨骼变形等并发症，乃至死亡等问题。历代医家认为本病虚实夹杂，病性为本虚标实，以天癸竭绝导致的肝肾不足、火不暖土导致的脾胃虚弱为虚，而在此基础上产生的淤血、食积、痰湿为实，存在“年老必虚→以虚致热→因热致瘀”的病机演变规律。故临床上治疗绝经后骨质疏松症当以“虚热瘀”为基本病机，以“调补肝肾，清化内热、祛瘀通络”为治疗大纲，通过辨证论治灵活化裁，达到阴平阳秘，五脏相安的目的，尽可能的提高患者的生活质量。","PeriodicalId":61242,"journal":{"name":"中华临床医药与护理","volume":"1 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sci-open.net/index.php/CN/article/download/4249/5418","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147893809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
针刺疗法通过调控细胞程序性死亡干预IS预后 针刺疗法通过调控细胞程序性死亡干预IS预后
中华临床医药与护理 Pub Date : 2025-10-20 DOI: 10.63887/cn.2025.1.6.15
刘力天
{"title":"针刺疗法通过调控细胞程序性死亡干预IS预后","authors":"刘力天","doi":"10.63887/cn.2025.1.6.15","DOIUrl":"https://doi.org/10.63887/cn.2025.1.6.15","url":null,"abstract":"缺血性卒中（IS）因高致残率与死亡率，造成严重的社会负担。应用神经保护疗法改善患者预后是当前的研究重点，而调控作用广泛的多种细胞程序性死亡（PCD）已成为IS神经保护的重要方向。针刺疗法凭借其多靶点、多途径的核心优势，在调控IS后PCD以发挥神经保护作用方面展现出巨大潜力。本文旨在综述PCD在IS中的影响及针刺干预的相关研究，以期为该领域的深入探索提供参考。","PeriodicalId":61242,"journal":{"name":"中华临床医药与护理","volume":"1 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sci-open.net/index.php/CN/article/download/4241/5410","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147900028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
手术室护理干预对腰椎间盘突出症行后路椎间盘镜治疗效果的影响 手术室护理干预对腰椎间盘突出症行后路椎间盘镜治疗效果的影响
中华临床医药与护理 Pub Date : 2025-10-12 DOI: 10.63887/cn.2025.1.5.15
陈文君
{"title":"手术室护理干预对腰椎间盘突出症行后路椎间盘镜治疗效果的影响","authors":"陈文君","doi":"10.63887/cn.2025.1.5.15","DOIUrl":"https://doi.org/10.63887/cn.2025.1.5.15","url":null,"abstract":"目的：分析手术室护理干预对腰椎间盘突出症行后路椎间盘镜治疗效果的影响。方法：该研究将2022.09月至2024.09月到医院行后路椎间盘镜治疗的腰椎间盘突出症患者当作研究对象，入选对象共44例，利用数字表随机排序法进行分组，分为对照组（纳入该组的患者进行常规护理，n=22）与研究组（列入该组的患者进行手术室护理干预，n=22）。对比两组的手术指标、心理应激、腰部疼痛、腰椎功能及生活质量。结果：在手术时长、术后下床时间及住院时间上，研究组短于对照组（P＜0.05）。在HAMA评分与HAMD评分上，研究组低于对照组（P＜0.05）。在VAS评分、ODI评分及SF-36评分上，研究组优于对照组（P＜0.05）。结论：在腰椎间盘突出症患者行后路椎间盘镜手术治疗环节中辅助运用手术室护理干预，有助于优化手术指标，减轻心理应激反应，改善腰椎功能和生活质量，临床可进一步推广应用。","PeriodicalId":61242,"journal":{"name":"中华临床医药与护理","volume":"1 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sci-open.net/index.php/CN/article/download/3896/5061","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147916575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
质子泵抑制剂联合根除幽门螺杆菌方案治疗反流性食管炎的疗效对比 质子泵抑制剂联合根除幽门螺杆菌方案治疗反流性食管炎的疗效对比
中华临床医药与护理 Pub Date : 2025-10-12 DOI: 10.63887/cn.2025.1.5.16
董晓东
{"title":"质子泵抑制剂联合根除幽门螺杆菌方案治疗反流性食管炎的疗效对比","authors":"董晓东","doi":"10.63887/cn.2025.1.5.16","DOIUrl":"https://doi.org/10.63887/cn.2025.1.5.16","url":null,"abstract":"系统分析质子泵抑制剂（PPI）联合幽门螺杆菌（Hp）根除方案对反流性食管炎（GERD）的治疗效果，探讨其在症状缓解、黏膜愈合、复发率控制等方面的优势，为临床提供参考。结合近年相关文献与临床数据，对比PPI单药治疗与PPI联合根除Hp治疗在疗效、安全性和长期预后方面的差异，进行多维度分析。PPI单药方案能显著缓解GERD症状并促进短期愈合，但复发率高；PPI联合Hp根除方案在症状改善、食管黏膜修复、Hp清除及复发率降低方面表现出综合优势。PPI联合Hp根除治疗是更为有效的策略，不仅提高治疗成功率，还能改善患者生活质量与远期预后，对临床具有较高推广价值。","PeriodicalId":61242,"journal":{"name":"中华临床医药与护理","volume":"1 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sci-open.net/index.php/CN/article/download/3897/5062","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147896704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
帕金森病吞咽障碍康复护理的研究进展 帕金森病吞咽障碍康复护理的研究进展
中华临床医药与护理 Pub Date : 2025-10-03 DOI: 10.63887/cn.2025.1.5.9
黄新愉
{"title":"帕金森病吞咽障碍康复护理的研究进展","authors":"黄新愉","doi":"10.63887/cn.2025.1.5.9","DOIUrl":"https://doi.org/10.63887/cn.2025.1.5.9","url":null,"abstract":"帕金森病是常见的神经系统退行性疾病,吞咽障碍是其常见并发症，严重影响患者的生活质量，影响营养摄入，甚至会危及患者生命。本文综述了帕金森病吞咽障碍康复护理的研究进展，涵盖吞咽康复护理中的摄食训练、呼吸训练等内容，以及刺激疗法中的多种方法，包括酸冰刺激、神经肌肉电刺激、耳穴电刺激等，还探讨了针灸辅助治疗的作用,旨在为临床护理提供参考，从而提高帕金森病吞咽障碍患者的康复效果。","PeriodicalId":61242,"journal":{"name":"中华临床医药与护理","volume":"1 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sci-open.net/index.php/CN/article/download/3624/4805","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147907601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
海参皂苷类成分在中药配伍中的应用及其抗肿瘤与免疫调节机制研究 海参皂苷类成分在中药配伍中的应用及其抗肿瘤与免疫调节机制研究
中华临床医药与护理 Pub Date : 2025-09-14 DOI: 10.63887/cn.2025.1.4.2
李继红, 李秋红
{"title":"海参皂苷类成分在中药配伍中的应用及其抗肿瘤与免疫调节机制研究","authors":"李继红, 李秋红","doi":"10.63887/cn.2025.1.4.2","DOIUrl":"https://doi.org/10.63887/cn.2025.1.4.2","url":null,"abstract":"海参作为传统滋补佳品，在中医理论中具有“补肾益精，养血润燥”的功效。近年来，随着现代药理学研究的深入，海参中独特的皂苷类成分因其显著的抗肿瘤、免疫调节、抗真菌等生物活性而备受关注。本文基于相关文献，聚焦海参皂苷类成分在中药配伍中的应用及其在抗肿瘤与免疫调节方面的作用机制研究进展，并探讨其发展前景。","PeriodicalId":61242,"journal":{"name":"中华临床医药与护理","volume":"1 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sci-open.net/index.php/CN/article/download/3021/3962","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147885242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信
小红书