药剂与药理学:英文版Pub Date : 2023-08-28DOI: 10.17265/2328-2150/2023.08.001
Ajinkya Chaudhari, Payaam Vohra, Akshata Geedh
{"title":"A Comprehensive Overview of Models for Hepatoprotective Activity Screening","authors":"Ajinkya Chaudhari, Payaam Vohra, Akshata Geedh","doi":"10.17265/2328-2150/2023.08.001","DOIUrl":"https://doi.org/10.17265/2328-2150/2023.08.001","url":null,"abstract":": The liver is a crucial imperative organ that is involved in various kinds of metabolic activity and a very stable accessory gland for the digestive system. At this moment, liver dysfunction is a major source of destruction, and its widespread is accentuated in the developed republics. Long-term or persistent inflammation and oxidative stress due to any reason have a substantial impact on the beginning and continuation of chronic diseases such as hepatocellular carcinoma, liver cirrhosis, liver fibrosis, and other hepatic conditions. Liver diseases classified as hepatosis, cirrhosis and acute or chronic hepatitis are one amongst the most severe ailments This review deals with well-established in vivo , in vitro and in silico models for analysing the hepatoprotective activity of extract/drugs. Consequently, animal models are being developed to impressionist hepatic ailments. From several decades, researchers are using distinctive animal models for discovering and understanding the pathogenesis of hepatic ailments. This current cram has been framed to discuss numerous new and traditional experimental models for hepatotoxicity studies. Numerous animal models have evolved to evaluate the pathogenesis and develop drugs for hepatotoxicity. Experimental modes of hepatotoxicity are influential for invention of novel molecular signalling trails for the improvement of human health. This article aims to explore and unfold various possible models available for hepatoprotective models. This miniature review article highlights the hepatopathy models that are being used to observe the activities of liver injuries under hepatotoxic agents.","PeriodicalId":59706,"journal":{"name":"药剂与药理学:英文版","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45974760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
药剂与药理学:英文版Pub Date : 2023-07-28DOI: 10.17265/2328-2150/2023.07.001
Majid Rezaei Basiri
{"title":"New Findings for Diabetes II Management","authors":"Majid Rezaei Basiri","doi":"10.17265/2328-2150/2023.07.001","DOIUrl":"https://doi.org/10.17265/2328-2150/2023.07.001","url":null,"abstract":"","PeriodicalId":59706,"journal":{"name":"药剂与药理学:英文版","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45965123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
药剂与药理学:英文版Pub Date : 2023-06-28DOI: 10.17265/2328-2150/2023.06.001
Kaushal Chhayani, Parth Daxini, Priya Patel
{"title":"An Overview on Medicinal Leech Therapy","authors":"Kaushal Chhayani, Parth Daxini, Priya Patel","doi":"10.17265/2328-2150/2023.06.001","DOIUrl":"https://doi.org/10.17265/2328-2150/2023.06.001","url":null,"abstract":": In the traditional treatment of pain and inflammatory illnesses, Hirudo medicinalis (Medicinal leeches) are used therapeutically. Leeches are connected to the afflicted areas and start sucking blood after a first, painless bite. Instead of the blood extracted during biting, the majority of these therapeutic benefits originate from the numerous bioactive substances found in saliva, such as hyaluronidase, hirudin, calin, destabilase, apyrase, eglin, and many others. Treatments focus on reducing regional pain syndromes, primarily for osteoarthritis of the knee or other joint conditions. The use of this technology extends to plastic surgery, where it is used to maintain blood flow in clogged skin flaps, reconstructive procedures, cardiovascular complications, varicose veins, haemorrhoids, gastrointestinal disorders, dermatology, gynaecological abnormalities, and traumatic conditions like the reattachment of severed extremities, finger, toe, and ear. Recently, new applications in the treatment of diabetes, asthma and cancer have been found. Due to the increasing therapeutic potential of HT, researchers are striving to find and synthesize several new salivary compounds.","PeriodicalId":59706,"journal":{"name":"药剂与药理学:英文版","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44669873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
药剂与药理学:英文版Pub Date : 2023-06-28DOI: 10.17265/2328-2142/2023.02.001
Vuong Tran Quang
{"title":"Potential Application of iRap for Road Safety Assessment under Mixed Traffic Condition Case Study: Le Van Viet Street in Ho Chi Minh City","authors":"Vuong Tran Quang","doi":"10.17265/2328-2142/2023.02.001","DOIUrl":"https://doi.org/10.17265/2328-2142/2023.02.001","url":null,"abstract":": Road transport safety policies have emphasized road infrastructure safety design and engineering as a core function. However, in developing countries like Vietnam, this approach has been slower to adopt, resulting in substandard roads. In-depth studies of accident locations indicate that road environment factors contribute significantly to road accidents in Vietnam and road design features are associated with specific accident types and hazards. Proactive and reactive approaches, such as road safety audit, inspection, assessment, and treatment of hazardous locations, are necessary to ensure that the road and its environment are safe. This paper provides an overview of road safety in Vietnam in general, and Ho Chi Minh in particular, including its factors and characteristics, as well as road infrastructure safety improvements. The iRap tool for road safety inspection and assessment is highlighted as a potential method for systematically analyzing road infrastructure deficiencies and providing targeted countermeasures to improve road safety under mixed traffic conditions.","PeriodicalId":59706,"journal":{"name":"药剂与药理学:英文版","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48800700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
药剂与药理学:英文版Pub Date : 2023-06-28DOI: 10.17265/2328-2142/2023.02.003
Daniel Olisa Iweze
{"title":"The Imperative of Inter-Modal Transport System in Nigeria: A Case Study of Asaba and Onitsha Transportation System","authors":"Daniel Olisa Iweze","doi":"10.17265/2328-2142/2023.02.003","DOIUrl":"https://doi.org/10.17265/2328-2142/2023.02.003","url":null,"abstract":": Transport system in Nigeria is predominantly uni-modal as it is estimated that over ninety per cent of goods and passengers are transported by road. The over-reliance on road transport for the transportation of bulk of goods and people has contributed greatly to the deterioration of Nigeria’s roads and the attendant increase in road maintenance costs. Researches by scholars have revealed that a single means of transport cannot adequately serve the intra and inter-transport needs of the majority of people living in urban cities. Asaba and Onitsha located at the banks of river Niger have outlets for water-based transport services, which are yet to be fully developed and integrated with the dominant road transport system. Bulky goods that arrived by sea are best transported from the port through the waterways to inland ports. The Onitsha port, which was established in the 1980s has not been functioning and this makes road transport the only option for transportation of goods and people between the two cities. It is against this background, that this paper surveys the transport modes in the two cities and advocates the need for inter-modal transport modes that would ensure seamless movement of people and goods between the two cities and with other parts of the country. The paper submits that for the two cities to derive full benefits of the different transport modes, there is need for efficient inter-modal transport systems linking the two cities and regions in order to minimize the frequent chaotic traffic congestion on the Niger bridge. The optimal utilization of inter-modal transport modes would enable each transport mode to perform its distinctive roles which would lead to faster transportation of passengers and goods as well as ensure reduction in transport costs. The paper also proffers ways of achieving an efficient inter-modal transport system between Asaba and Onitsha and Nigeria at large.","PeriodicalId":59706,"journal":{"name":"药剂与药理学:英文版","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44406344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
药剂与药理学:英文版Pub Date : 2023-06-28DOI: 10.17265/2328-2150/2023.06.002
Arturo L Delgado, Mfuneko Kopolo, Ernesto Rosales, Anelisa Mnqandi, Chukwuma Joseph Onyeche, Moehketsi Thabane, Yamkela Luke
{"title":"Outcome of the Treatment of Hydatid Disease in Children over a Period of 8 Years","authors":"Arturo L Delgado, Mfuneko Kopolo, Ernesto Rosales, Anelisa Mnqandi, Chukwuma Joseph Onyeche, Moehketsi Thabane, Yamkela Luke","doi":"10.17265/2328-2150/2023.06.002","DOIUrl":"https://doi.org/10.17265/2328-2150/2023.06.002","url":null,"abstract":"","PeriodicalId":59706,"journal":{"name":"药剂与药理学:英文版","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41949414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
药剂与药理学:英文版Pub Date : 2023-06-28DOI: 10.17265/2328-2150/2023.06.003
Ana Elena Rodríguez Cadalso, Regina de la Caridad Rodríguez Muñoz, Teresa Turiño Macarena, Gonzalo, Eduardo Rafael Águila Turiño, Lisnay Trujillo Rodríguez, Yamel Bárbaro Pérez Vásquez, Manuel Antonio Pérez García
{"title":"Level of Knowledge on Medicinal Plants in the Class Group of Elderly in Trinidad, 2023","authors":"Ana Elena Rodríguez Cadalso, Regina de la Caridad Rodríguez Muñoz, Teresa Turiño Macarena, Gonzalo, Eduardo Rafael Águila Turiño, Lisnay Trujillo Rodríguez, Yamel Bárbaro Pérez Vásquez, Manuel Antonio Pérez García","doi":"10.17265/2328-2150/2023.06.003","DOIUrl":"https://doi.org/10.17265/2328-2150/2023.06.003","url":null,"abstract":": Objectives: To characterize the traditional use of medicinal plants in old men belonging to the class group of elderly of Trinidad in 2023. Methods: To carry out study over the past 5 years and to present a general vision on the use of medicinal plants in the elderly. It was carried out an observational and transversal descriptive study of this class in the period from November 2022 to March 2023. Descriptive statistic was used. Results: The (76.2%) of the group and the feminine sex (95.2%), prevailed with over 65 years. The 95.33% (N = 21) referred knowledge on medicinal plants, (76.2%) with Technical scholarship or high school levels. The 57.1% referred as main source of information radio and television and 71.4% over 30 years consumes medicinal plants. 57.1% request advice on medicinal plants from others old men and 66.6% didn't know that some medicinal plants can produce damages to the organism if they are not use correctly. Conclusions: With the instruments applied, it could be determined the necessity to teach topics related to medicinal plants and to know the importance of sowing medicinal plants in their houses using valid information with scientific arguments. Technological prevision based on the search of articles in the Virtual Library in Health (BVS) and using the key words “medicinal plant”/“old men”/“class group of elderly”/“elder adults”/“elderly”.","PeriodicalId":59706,"journal":{"name":"药剂与药理学:英文版","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48463624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
药剂与药理学:英文版Pub Date : 2023-06-28DOI: 10.17265/2328-2142/2023.02.002
Pedja Sovilj
{"title":"Sustainable Transport Futures Transition of Belgrade to Low-Carbon Urban Transport","authors":"Pedja Sovilj","doi":"10.17265/2328-2142/2023.02.002","DOIUrl":"https://doi.org/10.17265/2328-2142/2023.02.002","url":null,"abstract":"","PeriodicalId":59706,"journal":{"name":"药剂与药理学:英文版","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45611991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
药剂与药理学:英文版Pub Date : 2023-06-28DOI: 10.17265/2328-2142/2023.02.004
Vu Anh Tuan
{"title":"Urban Accessibility in Motorcycle Dependent Cities – Case Study in Ho Chi Minh City, Vietnam","authors":"Vu Anh Tuan","doi":"10.17265/2328-2142/2023.02.004","DOIUrl":"https://doi.org/10.17265/2328-2142/2023.02.004","url":null,"abstract":"","PeriodicalId":59706,"journal":{"name":"药剂与药理学:英文版","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48476110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}