亚洲儿科病例研究 Pub Date : 2023-01-01 DOI: 10.12677/acrp.2023.111002

坤杨

引用次数: 0

Predictive Significance of Bone Metabolism Indexes at Birth in Very Low Birth Weight Infants for Metabolic Bone Disease 极低出生体重儿出生时骨代谢指标对代谢性骨病的预测意义

亚洲儿科病例研究 Pub Date : 2023-01-01 DOI: 10.12677/acrp.2023.111001

冠桦陈

{"title":"Predictive Significance of Bone Metabolism Indexes at Birth in Very Low Birth Weight Infants for Metabolic Bone Disease","authors":"冠桦陈","doi":"10.12677/acrp.2023.111001","DOIUrl":"https://doi.org/10.12677/acrp.2023.111001","url":null,"abstract":"Objective: To investigate the predictors of metabolic bone disease in very low birth weight infants. Methods: 129 very low birth weight infants diagnosed with metabolic bone disease were selected as the case group; 47 very low birth weight infants with non-metabolic bone disease during the same period were selected as the control group. The serum calcium, serum phosphorus, serum calcium and phosphorus product, and serum alkaline phosphatase at birth were analyzed and compared between the two groups of infants. Results: The mean serum calcium, serum phosphorus, and serum calcium and phosphorus product of very low birth weight infants diagnosed with metabolic bone disease after discharge were not significantly different from those in the control group ( P values were 0.574, 0.360, and 0.325, respectively); The enzyme level of serum alkaline phosphate was lower than the control group, and the difference was statistically significant ( P = 0.017). Using ROC curve analysis, the area under the curve of serum alkaline phosphatase was 0.519; The sensitivity of serum alkaline phosphatase (241.5 U/L) for the prediction of metabolic bone disease was 84.5%, the specificity was 31.9%, 95%CI: 0.413~0.624. Conclusions: There may be differences in serum alkaline phosphatase at birth in very low birth weight infants with MBDP, but they are not helpful in predicting the occurrence of metabolic bone disease.","PeriodicalId":58234,"journal":{"name":"亚洲儿科病例研究","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66125475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

De Winter Syndrome in Children: A Case Report 儿童德温特综合征1例报告

亚洲儿科病例研究 Pub Date : 2022-01-01 DOI: 10.12677/acrp.2022.101001

中兴周

引用次数: 0

A Case with Idiopathic Inflammatory Myositis in Children 儿童特发性炎性肌炎1例

亚洲儿科病例研究 Pub Date : 2022-01-01 DOI: 10.12677/acrp.2022.104004

椰陈

引用次数: 0

A Dual-Center Study of Risk Factors for Metabolic Bone Disease in Very Low Birth Weight Preterm Infants 极低出生体重早产儿代谢性骨病危险因素的双中心研究

亚洲儿科病例研究 Pub Date : 2022-01-01 DOI: 10.12677/acrp.2022.103003

冠桦陈

{"title":"A Dual-Center Study of Risk Factors for Metabolic Bone Disease in Very Low Birth Weight Preterm Infants","authors":"冠桦陈","doi":"10.12677/acrp.2022.103003","DOIUrl":"https://doi.org/10.12677/acrp.2022.103003","url":null,"abstract":"Objective: To investigate the nutritional status of premature infants with a birth weight less than 1500 g in Guangzhou and Dongguan and the related influencing factors of metabolic bone disease (MBDP) after birth. Methods: A retrospective survey was used to collect preterm births with birth weight < 1500 g and gestational age less than 37 weeks from September 1, 2020 to November 30, 2021 in Guangzhou Women’s and Children’s Medical Center and 2 hospitals in Dongguan Maternal and Child Health Hospital. Clinical data of children, 45 cases of metabolic bone disease in the con-trol group and 107 cases in the normal group, including birth status, feeding status, calcium and phosphorus metabolism status during hospitalization, hospital days and body weight growth of very low birth weight infants A descriptive analysis was performed and the associated factors of MBDP were analyzed. Results: The incidence of MBDP in very low birth weight infants was 29.6% (45/152), and there was a statistically significant difference in the gender ratio between the two groups ( χ 2 = 155.592, P = 0.000). There were significant differences in the length of hospital stay and gestational age at birth (P < 0.05). Logistic regression analysis showed that fewer days in hospital and older gestational age were protective factors for metabolic bone disease (all P < 0.05). Conclusions: Low gestational age, long hospitalization days and male infants may be related risk factors for MBDP in very low birth weight infants.","PeriodicalId":58234,"journal":{"name":"亚洲儿科病例研究","volume":"234 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66125415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Two Cases of Childhood Acute Lymphoblastic Leukemia Combined with Pneumocystis Pneumonia and Literature Review 儿童急性淋巴细胞白血病合并肺囊虫性肺炎2例并文献复习

亚洲儿科病例研究 Pub Date : 2021-01-01 DOI: 10.12677/acrp.2021.92002

虹馨陈

引用次数: 0

Incomplete Kawasaki Disease Complicated with Hemophilic Syndrome: A Case Report and Literature Review 不完全川崎病合并血友病综合征1例报告并文献复习

亚洲儿科病例研究 Pub Date : 2021-01-01 DOI: 10.12677/acrp.2021.91001

芳陈

引用次数: 0

Acute Lymphoblastic Leukemia with Posterior Reversible Encephalopathy Syndrome in Children: A Report of 2 Cases and Liter-Ature Review 儿童急性淋巴细胞白血病合并后部可逆性脑病综合征2例报告并文献复习

亚洲儿科病例研究 Pub Date : 2020-01-01 DOI: 10.12677/acrp.2020.82003

雷张