Gold Bulletin最新文献_第5页

Evaluation of penicillin residues in milk by ELISA using aptamer bonded to gold nanoparticles 纳米金适配体结合酶联免疫吸附法测定牛奶中青霉素残留

IF 2.2 4区工程技术

Gold Bulletin Pub Date : 2022-08-09 DOI: 10.1007/s13404-022-00319-7

Hossein Toghyani Dolatabadi, Mahdieh Izadi, Ali Mohammad Tamaddon

引用次数: 0

Characterization of breast cancer antibody (anti-HER-II) conjugated on PEGylated gold nanourchin for active targeting 聚乙二醇化金纳米蛋白偶联的乳腺癌抗体(抗her - ii)的活性靶向鉴定

IF 2.2 4区工程技术

Gold Bulletin Pub Date : 2022-06-02 DOI: 10.1007/s13404-022-00316-w

Mohammad E. Khosroshahi, Yesha Patel, Roxana Chabok

{"title":"Characterization of breast cancer antibody (anti-HER-II) conjugated on PEGylated gold nanourchin for active targeting","authors":"Mohammad E. Khosroshahi, Yesha Patel, Roxana Chabok","doi":"10.1007/s13404-022-00316-w","DOIUrl":"10.1007/s13404-022-00316-w","url":null,"abstract":"<div><p>Conjugation and characterization of poly-ethylene–glycol (PEG)-functionalized gold nanourchin (GNU) with breast cancer biomarker HER-II monoclonal antibody (mAb) (i.e., anti-HER-II) for selective targeting are described. After the functionalization of GNU with PEG, the surface plasmon resonance (SPR) peak was red-shifted, indicating the increase in the hydrodynamic size of the GNU. The Fourier-transform near-infrared spectroscopy (FT-NIR) second derivative result of GNU-PEG provided overtone and combination bands of fundamental vibrational modes of protein molecular structures between 4000 and 7500 cm<sup>−1</sup>. This mainly included C–H combination and CH<sub>2</sub> bonds, O–H first stretch overtones, the C–H first stretch overtone, and the CH<sub>2</sub> combination first overtone. The UV–Vis absorbance showed a strong absorption of light at 227 and 275 nm corresponding to tyrosine peaks. The fluorescence emission peak at 315 nm corresponds to Stokes shift when excited by 280 nm corresponding to tyrosine in the mAb, and the peak at 497 nm likely corresponds to alanine. After conjugation of GNU-PEG with mAb, the FT-NIR indicated the bands corresponding to NH<sub>2</sub> combination and amino acids, first overtone symmetric and antisymmetric OH stretching, C–H combination, and the second overtones and combination modes. Surface-enhanced Raman scattering (SERS) provided useful information on the molecular structure and composition of the sample within 300–3500 cm<sup>−1</sup>. The intensity behavior of SERS signals exhibited a statistical nature due to Brownian fluctuating movement. In addition, the intensity and number of SERS lines varied with the laser power. The dominant peaks were corresponding to histidine, tyrosine, tryptophan, phenylalanine, and C–H, N–H, C–N, and O–H bonds.</p></div>","PeriodicalId":581,"journal":{"name":"Gold Bulletin","volume":"55 2","pages":"149 - 159"},"PeriodicalIF":2.2,"publicationDate":"2022-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"4089711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of chitosan-modified gold nanoparticles in Lemna valdiviana and Daphnia pulex 壳聚糖修饰的金纳米颗粒在水蚤和水蚤中的作用

IF 2.2 4区工程技术

Gold Bulletin Pub Date : 2022-01-13 DOI: 10.1007/s13404-021-00306-4

Paulina Abrica-González, E. Zumelzu, Jorge Nimptsch, José Abraham Balderas-López, Alejandro Muñoz-Diosdado, Ignacio Moreno-Villoslada, Mario E. Flores

{"title":"The effect of chitosan-modified gold nanoparticles in Lemna valdiviana and Daphnia pulex","authors":"Paulina Abrica-González, E. Zumelzu, Jorge Nimptsch, José Abraham Balderas-López, Alejandro Muñoz-Diosdado, Ignacio Moreno-Villoslada, Mario E. Flores","doi":"10.1007/s13404-021-00306-4","DOIUrl":"10.1007/s13404-021-00306-4","url":null,"abstract":"<div><h2>Abstract\u0000</h2><div><p>Gold nanoparticles (AuNPs) are nowadays used in many areas of science, particularly in medicine as drug release and gene carriers. The extensive use of these materials makes imperative the study of their effects on the environment after their disposal, that mostly affects the aquatic media. The present work explores the bioaccumulation and toxicity of chitosan-functionalized and non-functionalized gold nanoparticles, with primary producers (<i>Lemna valdiviana</i>) and primary consumers (<i>Daphnia pulex</i>) aquatic organisms. Bioaccumulation of 27.4 nm AuNPs and 43.1 nm chitosan-gold nanoparticles (CO-AuNPs) was evaluated in both microorganisms, finding accumulation of AuNPs and inhomogeneous aggregation of CO-AuNPs in <i>Daphnia pulex</i> gut, and internalization of both types of nanoparticles in <i>Lemna valdiviana</i> cell walls. The effective concentration of nanomaterial for 50% survival (LC50) of <i>Daphnia pulex</i> organisms was 1.13 mg/L for AuNPs and 0.96 mg/L for CO-AuNPs in the acute test. In <i>Lemna valdiviana</i> 7-day test, the EC50 for area and frond number were 1.19 mg/L and 1.26 mg/L, respectively, for AuNPs, 1.53 mg/L and 1.44 mg/L, respectively, for CO-AuNPs, finding higher toxicity of CO-AuNPs to <i>Daphnia pulex</i>, and AuNPs to <i>Lemna valdiviana</i>. The obtained results suggest that the effects of nanomaterials on the growth and survival of key organisms deserve further study, as this may lead to the development of appropriate environmental regulations.</p></div></div>","PeriodicalId":581,"journal":{"name":"Gold Bulletin","volume":"55 1","pages":"77 - 91"},"PeriodicalIF":2.2,"publicationDate":"2022-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"4539717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Study on the growth kinetics of Au nanorods based on local surface plasmon resonance 基于局部表面等离子体共振的金纳米棒生长动力学研究

IF 2.2 4区工程技术

Gold Bulletin Pub Date : 2021-10-29 DOI: 10.1007/s13404-021-00299-0

Liqing Meng, Zongxiao Li, Yousheng Deng

引用次数: 0

The age hardenability of 22 karat gold (Au-5.8wt.%Cu-2.5wt.%Ag) alloyed with titanium 研究了22k金(Au-5.8wt.%Cu-2.5wt.%Ag)与钛合金的时效淬透性

IF 2.2 4区工程技术

Gold Bulletin Pub Date : 2021-10-27 DOI: 10.1007/s13404-021-00301-9

K. M. Saradesh, K. R. Ravi, G. S. Vinodkumar

{"title":"The age hardenability of 22 karat gold (Au-5.8wt.%Cu-2.5wt.%Ag) alloyed with titanium","authors":"K. M. Saradesh, K. R. Ravi, G. S. Vinodkumar","doi":"10.1007/s13404-021-00301-9","DOIUrl":"10.1007/s13404-021-00301-9","url":null,"abstract":"<div><p>The age hardenability of 22 karat gold (Au-5.8wt.%Cu-2.5wt.%Ag) alloyed with Ti at various concentrations (0.5, 0.75, and 1 wt.%) was studied. The addition level of Ti is compensated with Ag to maintain the purity of gold in 22 karat, i.e., 91.75 wt.%. The Ti containing 22 karat gold was prepared by melting Au, Cu, and Ag and adding Ti via Au-6wt.%Ti master alloy. The castings obtained were cold-rolled into thin sheet (90% reduction). Both the cast and cold-rolled sheets were subjected to age hardening treatment (solutionizing and artificial aging). Artificial aging was performed as a function of time at 550 °C to identify the peak aging. At all addition level of Ti, the 22 karat gold responded well to the age hardening treatment. The cold-worked sheet samples showed faster peak aging within 30 min. and higher peak hardness than their cast counterpart. Increasing the Ti concentration increases the peak hardness of both cold-rolled sheet and casting samples. Transmission electron microscopic analysis of the peak aged cold-rolled sheet samples shows uniformly distributed coherent Au<sub>4</sub>Ti precipitates in Au matrix which contribute to the higher hardness.</p></div>","PeriodicalId":581,"journal":{"name":"Gold Bulletin","volume":"54 2","pages":"105 - 113"},"PeriodicalIF":2.2,"publicationDate":"2021-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s13404-021-00301-9.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"5064971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Do LBMA gold price follow random-walk? LBMA黄金价格遵循随机游走吗?

IF 2.2 4区工程技术

Gold Bulletin Pub Date : 2021-09-15 DOI: 10.1007/s13404-021-00300-w

Biswabhusan Bhuyan, Subhamitra Patra, Ranjan Kumar Bhuian

引用次数: 1

Anglo-Saxon bling — a warrior king’s Golden Helmet 盎格鲁-撒克逊人的珠宝——勇士国王的金头盔

IF 2.2 4区工程技术

Gold Bulletin Pub Date : 2021-06-11 DOI: 10.1007/s13404-021-00297-2

Frank Cooper

{"title":"Anglo-Saxon bling — a warrior king’s Golden Helmet","authors":"Frank Cooper","doi":"10.1007/s13404-021-00297-2","DOIUrl":"10.1007/s13404-021-00297-2","url":null,"abstract":"<div><p>In 2009, a metal detectorist discovered a hoard of Anglo-Saxon gold and silver in a field in Staffordshire. Hence, it quickly became known as ‘The Staffordshire Hoard’. It was, and remains, the biggest collection of Anglo-Saxon gold (4 kg) and silver (1.7 kg) ever discovered and comprised of more than 4000 fragments that equated to over 600 discrete objects and larger pieces. The Staffordshire Hoard is co-owned by Birmingham and Stoke-on-Trent City Councils and is cared for on behalf of the nation by Birmingham Museums Trust and The Potteries Museum & Art Gallery. Over the intervening years, most of the larger and recognisably important pieces have now been identified and catalogued. We now also know an exceptional amount about their probable methods of manufacture, artistic styles, date, and function. This paper focuses on what is now known to be one of the most fragmented yet magnificent of its objects, a Helmet that has been declared as being ‘fit for a king’, but which was found scattered into well over 1000 disparate fragments. Fragments that are now considered to make up around one-third of the Hoard’s total of finds and compose this single high-status Golden Helmet. Too damaged and incomplete to be re-joined or displayed in a form that delivers to the casual observer a true sense of the majesty of the original. Thus, the museums responsible for the collection commissioned an experimental reconstruction project to create two of the helmets for display in their shared Hoard collections.</p></div>","PeriodicalId":581,"journal":{"name":"Gold Bulletin","volume":"54 2","pages":"115 - 149"},"PeriodicalIF":2.2,"publicationDate":"2021-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s13404-021-00297-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"4468743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Synthesis, characterization, and in vitro drug release properties of AuNPs/p(AETAC-co-VI)/Q nanocomposite hydrogels AuNPs/p(AETAC-co-VI)/Q纳米复合水凝胶的合成、表征及体外释药性能

IF 2.2 4区工程技术

Gold Bulletin Pub Date : 2021-04-14 DOI: 10.1007/s13404-021-00295-4

Seçil Durmuş, Betul Yilmaz, Mehmet Rıza Kıvanç, Alper Onder, Pinar Ilgin, Hava Ozay, Ozgur Ozay

{"title":"Synthesis, characterization, and in vitro drug release properties of AuNPs/p(AETAC-co-VI)/Q nanocomposite hydrogels","authors":"Seçil Durmuş, Betul Yilmaz, Mehmet Rıza Kıvanç, Alper Onder, Pinar Ilgin, Hava Ozay, Ozgur Ozay","doi":"10.1007/s13404-021-00295-4","DOIUrl":"10.1007/s13404-021-00295-4","url":null,"abstract":"<p>In this study, the cationic monomer [2-(acryloyloxy)ethyl]trimethylammonium chloride solution (AETAC) and vinyl imidazole (VI) were used with the free radical polymerization technique, which is a simple and rapid synthesis method, to synthesize p(AETAC-co-VI) hydrogels. To increase the density of cationic charge on the hydrogel, it underwent the protonation process with HCl. The obtained p(AETAC-co-VI)/Q hydrogel was modified with Au nanoparticles to increase bactericidal effect to obtain the AuNPs/p(AETAC-co-VI)/Q nanocomposite hydrogel. The morphology and chemical structure of the hydrogels were characterized with SEM and FTIR. Additionally, the swelling capabilities were tested in different pH media. XRD and TEM confirmed the formation of the nanocomposite hydrogel. The antibacterial activity of the hydrogels was tested against <i>E. coli</i> and <i>S. aureus</i>, and controlled release implementations were completed with sodium diclofenac (NaDc) drug. The NaDc drug release profiles of the hydrogels were researched using the Korsmeyer–Peppas model at 37 °C in different simulated buffer (pH 6.0, 7.2, and 8.0) solutions. It was found that both the hydrogel and nanocomposite hydrogel followed non-Fickian diffusion mechanisms as free release mechanism. Here, the maximum drug release efficacy was found to be 97%, and drug release was more rapid in basic media when release media were compared. The AuNPs/p(AETAC-co-VI)/Q nanocomposite hydrogels produced in this study with advanced antibacterial features were suitable for recommendation as good carriers for in vitro release of NaDc drugs in areas like the biomedical and pharmaceutical industries.</p>","PeriodicalId":581,"journal":{"name":"Gold Bulletin","volume":"54 2","pages":"75 - 87"},"PeriodicalIF":2.2,"publicationDate":"2021-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s13404-021-00295-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"4559402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

The facile synthesis of aerogel-like alumina highly-loaded with gold nanoparticles 高负载金纳米颗粒的气凝胶状氧化铝的简易合成

IF 2.2 4区工程技术

Gold Bulletin Pub Date : 2021-03-01 DOI: 10.1007/s13404-021-00294-5

N. S. Nesterov, A. S. Shalygin, T. S. Glazneva, V. P. Pakharukova, O. N. Martyanov

{"title":"The facile synthesis of aerogel-like alumina highly-loaded with gold nanoparticles","authors":"N. S. Nesterov, A. S. Shalygin, T. S. Glazneva, V. P. Pakharukova, O. N. Martyanov","doi":"10.1007/s13404-021-00294-5","DOIUrl":"https://doi.org/10.1007/s13404-021-00294-5","url":null,"abstract":"<p>A facile approach is proposed for the stabilization of gold nanoparticles within alumina matrix based on fast coprecipitation of colloidal gold and alumina sol in the supercritical carbon dioxide used as antisolvent. Acetylacetone was used as a stabilizer agent for the synthesis of alumina sol. Gold nanoparticles were synthesized from HAuCl<sub>4</sub> directly in liquid alumina sol in reaction with acetylacetone. Acetylacetone played the role of both a stabilizer agent for gold nanoparticles and a reducing agent. Obtained system is characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), infrared (IR) spectroscopy, and UV–Vis adsorption spectroscopy. The method allows us to synthesize aerogel-like alumina highly loaded with gold nanoparticles firmly fixed on oxide surface and uniformly distributed within alumina matrix. The proposed approach combines sol-gel and supercritical fluid methods for the synthesis and opens the wide prospects for preparation composites consisting of gold nanoparticles in oxide matrix with a uniform distribution. These gold-bearing systems may be of interest to a wide range of applications.</p>","PeriodicalId":581,"journal":{"name":"Gold Bulletin","volume":"54 1","pages":"69 - 74"},"PeriodicalIF":2.2,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s13404-021-00294-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"4043386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Preparation of Aunanorods@B-SiO2 准备Aunanorods@B-SiO2

IF 2.2 4区工程技术

Gold Bulletin Pub Date : 2021-02-20 DOI: 10.1007/s13404-021-00289-2

Liqing Meng, Huiqin Li

引用次数: 0