Elizabeth Barba, Borja Sánchez, Emanuel Burri, Anna Accarino, Eva Monclus, Isabel Navazo, Francisco Guarner, Abelardo Margolles, Fernando Azpiroz
{"title":"Abdominal distension after eating lettuce: The role of intestinal gas evaluated in vitro and by abdominal CT imaging.","authors":"Elizabeth Barba, Borja Sánchez, Emanuel Burri, Anna Accarino, Eva Monclus, Isabel Navazo, Francisco Guarner, Abelardo Margolles, Fernando Azpiroz","doi":"10.1111/nmo.13703","DOIUrl":"10.1111/nmo.13703","url":null,"abstract":"<p><strong>Background: </strong>Some patients complain that eating lettuce, gives them gas and abdominal distention. Our aim was to determine to what extent the patients' assertion is sustained by evidence.</p><p><strong>Methods: </strong>An in vitro study measured the amount of gas produced during the process of fermentation by a preparation of human colonic microbiota (n = 3) of predigested lettuce, as compared to beans, a high gas-releasing substrate, to meat, a low gas-releasing substrate, and to a nutrient-free negative control. A clinical study in patients complaining of abdominal distention after eating lettuce (n = 12) measured the amount of intestinal gas and the morphometric configuration of the abdominal cavity in abdominal CT scans during an episode of lettuce-induced distension as compared to basal conditions.</p><p><strong>Key results: </strong>Gas production by microbiota fermentation of lettuce in vitro was similar to that of meat (P = .44), lower than that of beans (by 78 ± 15%; P < .001) and higher than with the nutrient-free control (by 25 ± 19%; P = .05). Patients complaining of abdominal distension after eating lettuce exhibited an increase in girth (35 ± 3 mm larger than basal; P < .001) without significant increase in colonic gas content (39 ± 4 mL increase; P = .071); abdominal distension was related to a descent of the diaphragm (by 7 ± 3 mm; P = .027) with redistribution of normal abdominal contents.</p><p><strong>Conclusion and inferences: </strong>Lettuce is a low gas-releasing substrate for microbiota fermentation and lettuce-induced abdominal distension is produced by an uncoordinated activity of the abdominal walls. Correction of the somatic response might be more effective than the current dietary restriction strategy.</p>","PeriodicalId":57320,"journal":{"name":"Journal of Coal Science EngineeringChina","volume":"18 1","pages":"e13703"},"PeriodicalIF":3.5,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/nmo.13703","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74784260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ethanol exposure in prenatal and early postnatal induced cardiac injury in rats: involvement of oxidative stress, Hsp70, ERK 1/2, JNK, and apoptosis in a 3-month follow-up study.","authors":"Alireza Shirpoor, Reza Gaderi, Roya Naderi","doi":"10.1007/s12192-019-01015-w","DOIUrl":"10.1007/s12192-019-01015-w","url":null,"abstract":"<p><p>Alcohol exposure during pregnancy induces a wide range of structural and functional abnormalities in the fetal heart. However, the underlying mechanism of this phenomenon is not well known. This study was undertaken to elucidate probable mechanisms of myocardial damage induced by prenatal and early postnatal ethanol treatment. Pregnant Wistar rats received ethanol 4.5 g/kg BW once per day from the seventh day of gestation (GD7) throughout lactation. The oxidative stress injury of the myocardium in pups was evaluated by measuring levels of oxidative stress biomarkers. Histopathological examinations and Western blot were performed to evaluate histological features, apoptosis, and molecular alterations in the myocardial tissue of male pups on the postnatal day 21 (PN-21) and postnatal day 90 (PN-90). The results showed that maternal ethanol consumption caused oxidative stress (impaired total antioxidant capacity and malondialdehyde), histological changes, and apoptosis of the myocardium in the pups on PN-21 and PN-90. At the molecular levels, Western blot analysis revealed that ethanol modulated the protein expression of p-ERK1/2, p-JNK, and Hsp70 in the myocardial tissue of the pups after 21 and 90 days of birth compared with the controls. These findings revealed that maternal ethanol intake induced cardiac toxicity in part, mediated by oxidative stress and apoptosis in the pups. A further mechanism study revealed that ethanol enhanced ERK1/2 and JNK phosphorylation and Hsp70 protein expression.</p>","PeriodicalId":57320,"journal":{"name":"Journal of Coal Science EngineeringChina","volume":"17 1","pages":"917-926"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717233/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74783385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Computation model of proppant embedment depth based on dimensional analysis","authors":"Cong Lu, Jianchun Guo","doi":"10.1007/S12404-013-0407-X","DOIUrl":"https://doi.org/10.1007/S12404-013-0407-X","url":null,"abstract":"","PeriodicalId":57320,"journal":{"name":"Journal of Coal Science EngineeringChina","volume":"19 1","pages":"483-487"},"PeriodicalIF":0.0,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/S12404-013-0407-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"53166879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A practical framework for scenario-based optimal decision-making on water-deficient river ecological restoration in mining areas","authors":"Sen Yu, Mingyong Wang","doi":"10.1007/S12404-013-0420-0","DOIUrl":"https://doi.org/10.1007/S12404-013-0420-0","url":null,"abstract":"","PeriodicalId":57320,"journal":{"name":"Journal of Coal Science EngineeringChina","volume":"19 1","pages":"566-572"},"PeriodicalIF":0.0,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/S12404-013-0420-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"53168099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Simulation analysis of ammonia distribution in methanol production from coal water slurry gasification","authors":"Zhong Chen, Zhenghua Dai, Fuchen Wang","doi":"10.1007/S12404-013-0417-8","DOIUrl":"https://doi.org/10.1007/S12404-013-0417-8","url":null,"abstract":"","PeriodicalId":57320,"journal":{"name":"Journal of Coal Science EngineeringChina","volume":"19 1","pages":"546-553"},"PeriodicalIF":0.0,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/S12404-013-0417-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"53167601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Damage, failure and stability control of evolutionary process caused by re-exploitation of the residual resources","authors":"X. Feng, D. Duan, Q. Tian, Kai Wang, Li-bin Liu","doi":"10.1007/S12404-013-0404-0","DOIUrl":"https://doi.org/10.1007/S12404-013-0404-0","url":null,"abstract":"","PeriodicalId":57320,"journal":{"name":"Journal of Coal Science EngineeringChina","volume":"19 1","pages":"462-467"},"PeriodicalIF":0.0,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/S12404-013-0404-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"53167199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Current situation of simultaneous coal and methane extraction technology in pressure-relieved coalbed group","authors":"Feng-chun Cai, Zegong Liu, Yi Luo","doi":"10.1007/S12404-013-0410-2","DOIUrl":"https://doi.org/10.1007/S12404-013-0410-2","url":null,"abstract":"","PeriodicalId":57320,"journal":{"name":"Journal of Coal Science EngineeringChina","volume":"19 1","pages":"500-506"},"PeriodicalIF":0.0,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/S12404-013-0410-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"53167101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Ma, Xiaosu Zhu, Wen-Bo Li, Xiao-jing Zhang, Shufeng Du
{"title":"Study on reaction characteristics of phenolic hydroxyl in coal by using the model compound during direct coal liquefaction","authors":"B. Ma, Xiaosu Zhu, Wen-Bo Li, Xiao-jing Zhang, Shufeng Du","doi":"10.1007/S12404-013-0416-9","DOIUrl":"https://doi.org/10.1007/S12404-013-0416-9","url":null,"abstract":"","PeriodicalId":57320,"journal":{"name":"Journal of Coal Science EngineeringChina","volume":"19 1","pages":"540-545"},"PeriodicalIF":0.0,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/S12404-013-0416-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"53167575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Detonation initiated disintegration of coal particle due to the maximum strain energy theory","authors":"D. M. Patadiya, S. Jaisankar, T. Sheshadri","doi":"10.1007/S12404-013-0401-3","DOIUrl":"https://doi.org/10.1007/S12404-013-0401-3","url":null,"abstract":"","PeriodicalId":57320,"journal":{"name":"Journal of Coal Science EngineeringChina","volume":"19 1","pages":"435-440"},"PeriodicalIF":0.0,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/S12404-013-0401-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"53166389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}