Ophthalmology. Glaucoma最新文献

{"title":"A Tree Inside the Eye: A Presenting Feature of Axenfeld-Rieger Syndrome.","authors":"Zefeng Yang, Fei Li, Xiulan Zhang","doi":"10.1016/j.ogla.2025.06.004","DOIUrl":"https://doi.org/10.1016/j.ogla.2025.06.004","url":null,"abstract":"","PeriodicalId":56368,"journal":{"name":"Ophthalmology. Glaucoma","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144593015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cumulative Incidence of Bleb-related Infections After Mitomycin C-augmented Filtration Surgery Over 10 Years in Japanese Glaucoma Patients.","authors":"Mitsuki Kambayashi, Rei Sakata, Asahi Fujita, Makoto Aihara, Yuko Ohno, Shiroaki Shirato","doi":"10.1016/j.ogla.2025.07.001","DOIUrl":"https://doi.org/10.1016/j.ogla.2025.07.001","url":null,"abstract":"<p><strong>Purpose: </strong>This study investigated the incidence rates and risk factors for bleb-related infections (BRIs) following mitomycin C (MMC)-augmented filtration surgeries, including trabeculectomy and Ex-Press implantation, in Japanese patients with glaucoma.</p><p><strong>Design: </strong>Retrospective cohort study SUBJECTS: 2,097 eyes from 1,508 patients who underwent MMC-augmented filtration surgery between 2008 and 2022.</p><p><strong>Methods: </strong>We reviewed and extracted the medical records of baseline characteristics, surgical details, and follow-up data. Patients were categorized by surgery type and glaucoma diagnosis. BRI cases were categorized by severity and analyzed in terms of demographic and surgical variables. Kaplan-Meier survival analysis was used to estimate the BRI incidence rate, and a Cox proportional hazards model was used to identify influencing factors.</p><p><strong>Main outcome measures: </strong>The cumulative incidence of BRI in all patients who underwent filtration surgery RESULTS: In total, 50 eyes with BRI (49 patients; mean age: 52.6 years; 21 eyes from females) were identified, yielding an overall incidence rate of 2.38%. Stage I-III infections were observed in 27, 15, and 8 eyes, respectively. The cumulative incidence of BRI increased over time, with estimated rates of 1.5 ± 0.3% (standard error) at 5 years, 3.8 ± 0.7% at 10 years, and 6.4 ± 1.4% at 14 years. Furthermore, 33 eyes out of 1,460 eyes with primary open-angle glaucoma developed BRI. Younger age at surgery was identified as a significant risk factor for BRI (hazard ratio: 0.970 per 1 year, P = 0.025).</p><p><strong>Conclusions: </strong>This study is the first to show that the risk of BRI continues to increase 10 years after MMC-augmented filtration surgery. When considering filtration surgery, it is important to take into account the patient's age and inform them of the benefits of the procedure and the long-term risk of infection.</p>","PeriodicalId":56368,"journal":{"name":"Ophthalmology. Glaucoma","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144602383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identifying Barriers and Improving Adherence to Follow-up of Childhood Glaucoma in South India.","authors":"Manju R Pillai, George Varghese Puthuran, David S Friedman, Vijayakumar Valaguru, Raheem Rahmathullah, Santhosha P Ganesh, Janani Rajendran, Iswarya Mani, Ramasamy Krishnadas, Maria Papadopoulos","doi":"10.1016/j.ogla.2025.06.013","DOIUrl":"https://doi.org/10.1016/j.ogla.2025.06.013","url":null,"abstract":"<p><strong>Aim: </strong>To understand predictors and barriers of adherence to follow-up and identify strategies to improve follow-up in childhood glaucoma.</p><p><strong>Design: </strong>Cross-sectional study.</p><p><strong>Subjects: </strong>Caregivers of children with glaucoma diagnosed between January 2014 and January 2019 residing within 200 km of the base hospital.</p><p><strong>Methods: </strong>Home visits were conducted with consenting caregivers to collect information on socioeconomic status, education, occupation, activities, and quality of life. Caregivers were subsequently invited to bring their affected children to the base hospital for a comprehensive eye evaluation. Adherence was defined as returning within 6 months of the recommended follow-up visit. Logistic regression was used to identify factors associated with adherence.</p><p><strong>Main outcome measures: </strong>Adherence to follow-up; association of adherence with socioeconomic status, caregiver education, prior glaucoma surgery, and travel-related barriers; perceived facilitators for improving follow-up.</p><p><strong>Results: </strong>Out of 147 caregivers who were interviewed in their homes, 142 reported to the base hospital with the child and were included in the analysis. Of these, 79(56%) remained adherent to follow-up. Caregivers of adherent children were more likely to be better educated (68.3% vs. 42.9% having at least high school education, p=0.018); they were more frequently from urban areas (19% vs. 8%, p=0.084), and more caregivers belonged to upper middle class (17.7% vs. 6.3%, p=0.027). Multivariable logistic regression adjusting for these factors showed that children who had undergone glaucoma surgery were 3.02 times more likely (95%CI=1.21-7.54) to be adherent. Travel distance to the hospital was not associated with adherence. Caregivers reported that cost incentives towards travel and medical expenses would encourage follow-up.</p><p><strong>Conclusion: </strong>Only half the children with childhood glaucoma remained adherent to follow-up. Lack of prior surgery followed by lower socioeconomic status were the key risk factors. Financial assistance may help improve long term follow-up.</p>","PeriodicalId":56368,"journal":{"name":"Ophthalmology. Glaucoma","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144585678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy of ICD-10 Glaucoma Codes in a Large Academic Practice.","authors":"Daniel L Liebman, Grace E Johnson, Anthony Marte, David S Friedman, Michael V Boland, Tobias Elze, Luo Song, Mengyu Wang, Lucy Q Shen","doi":"10.1016/j.ogla.2025.06.012","DOIUrl":"https://doi.org/10.1016/j.ogla.2025.06.012","url":null,"abstract":"<p><p>Manual chart review of 500 patients was performed to compare documented ICD-10 glaucoma codes with physicians' notes. ICD-10 accuracy was 88% to indicate a glaucoma diagnosis, and 81% to indicate a glaucoma subtype.</p>","PeriodicalId":56368,"journal":{"name":"Ophthalmology. Glaucoma","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lens Capsule Deposit in an Eye with Prior Trabeculectomy.","authors":"Helena Gali, Wendy W Liu","doi":"10.1016/j.ogla.2025.06.002","DOIUrl":"https://doi.org/10.1016/j.ogla.2025.06.002","url":null,"abstract":"","PeriodicalId":56368,"journal":{"name":"Ophthalmology. Glaucoma","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ologen-augmentation of Ahmed valves in pediatric glaucomas: 2-6 Year Follow-up.","authors":"Adam Jacobson, Brenda L Bohnsack","doi":"10.1016/j.ogla.2025.06.008","DOIUrl":"https://doi.org/10.1016/j.ogla.2025.06.008","url":null,"abstract":"<p><strong>Purpose: </strong>Determine 2 to 6 year outcomes of Ologen augmentation of Ahmed glaucoma devices (OAGD) in children with glaucoma.</p><p><strong>Design: </strong>Retrospective interventional case series SUBJECTS: Children (less than years of age) with glaucoma requiring surgery for IOP (intraocular pressure) control with at least 2 years of post-operative follow-up.</p><p><strong>Methods: </strong>Placement of OAGD between 2018 and 2022.</p><p><strong>Main outcome measures: </strong>Change in IOP, number of glaucoma medications and best corrected visual acuity (BCVA) from preoperative to final follow-up, Success of surgery (complete defined as IOP 5-20 mmHg without additional medications, visually devastating complication or additional IOP-lowering surgeries, qualified success defined as above except IOP control was maintained ± glaucoma medications.</p><p><strong>Results: </strong>Forty eyes of 28 patients underwent OAGD at median age of 2.6 years [IQR 0.6, 7.8]. Primary congenital glaucoma was the most common diagnosis (12 eyes of 9 patients) followed by glaucoma secondary to non-acquired ocular anomaly (11 eyes of 6 patients).Twenty-two eyes of 16 patients had prior glaucoma surgery (median 2, [IQR 1,2]). Preoperative IOP was median 27 mmHg [IQR 24, 35] on median 3 [IQR 2, 3] glaucoma medications. At final follow-up (median 3.6 years [IQR 2.9, 4.3]), IOP (median 15 mmHg [IQR 13, 17]) and glaucoma medications (median 0 [IQR 0,0]) were significantly decrease (p<0.0001). Complete success at final follow-up was 55% (22 of 40 eyes) with 3- and 5-year survival rates of 75% with 95% CI[59, 86] and 57% with 95% CI[35,74]. Qualified success rate was 75% (30 of 40 eyes) with 3- and 5- year survival rates of 87% with 95% CI[71, 95] and 67% with 95% CI[42, 83].</p><p><strong>Conclusions: </strong>While OAGD decreased IOP and the number of glaucoma medications, the high survival rates seen over the first 3 years decreased by 5 years.</p>","PeriodicalId":56368,"journal":{"name":"Ophthalmology. Glaucoma","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-Resolution Anterior Segment-OCT-Guided Management of Iris Bombe Due to Pupillary Block.","authors":"Alessandro Siligato, Angelica Dipinto, Sara Bochicchio","doi":"10.1016/j.ogla.2025.06.001","DOIUrl":"https://doi.org/10.1016/j.ogla.2025.06.001","url":null,"abstract":"","PeriodicalId":56368,"journal":{"name":"Ophthalmology. Glaucoma","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Survey of patient understanding and satisfaction in glaucoma filtering surgery.","authors":"Farid Akkouche, Paul Bastelica, Christophe Baudouin, Shaya Sable, Antoine Labbe","doi":"10.1016/j.ogla.2025.06.007","DOIUrl":"https://doi.org/10.1016/j.ogla.2025.06.007","url":null,"abstract":"<p><strong>Objectives: </strong>To assess patients' understanding of glaucoma surgery and their postoperative satisfaction, to study the factors that may influence them, and to investigate correlations between these two determining factors.</p><p><strong>Design: </strong>A multi-center observational study.</p><p><strong>Subjects: </strong>Patients scheduled for glaucoma filtration surgery were included.</p><p><strong>Methods: </strong>Participants responded preoperatively to a questionnaire developed after literature review, evaluating their understanding of the surgery, and to a second questionnaire evaluating their postoperative satisfaction, between 2 and 3 months after surgery.</p><p><strong>Main outcome measures: </strong>The primary outcomes were mean scores for preoperative understanding and postoperative satisfaction. The influence of demographic, clinical and surgical factors on comprehension and satisfaction was analyzed using univariate and multivariate models.</p><p><strong>Results: </strong>In this study, 97 patients responded to the questionnaire evaluating their understanding of the surgery preoperatively. Postoperative satisfaction could be evaluated in 86 of them. The mean understanding score was 13.4 ± 5.4 (out of 25). Level of education (p<0.01) and reading the French Society of Ophthalmology's information form on glaucoma filtering surgery (p<0.05) were statistically correlated with a better understanding after multivariate analysis. The mean postoperative satisfaction score was 7.13 ± 3.0 (out of 10). Needling (p<0.01) and resumption of hypotensive treatment (p<0.001) were statistically correlated with poorer satisfaction after multivariate analysis. In addition, poorer preoperative understanding was correlated with lower postoperative satisfaction with a Pearson coefficient of 0.42 [95% CI 0.23-0.57 (p<0.01)].</p><p><strong>Conclusion: </strong>Overall, patient understanding was limited, and poor understanding negatively influenced postoperative satisfaction.</p>","PeriodicalId":56368,"journal":{"name":"Ophthalmology. Glaucoma","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes of Hydrus Microstent with Cataract Surgery in Asian and Non-Asian Eyes with Normal Tension Glaucoma.","authors":"Debbie S Kuo, Sharon Y H Lee, Christos N Theophanous","doi":"10.1016/j.ogla.2025.06.006","DOIUrl":"https://doi.org/10.1016/j.ogla.2025.06.006","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the efficacy and safety of the Hydrus microstent in conjunction with cataract surgery in normal tension glaucoma (NTG) patients with minimum 12-month follow-up.</p><p><strong>Design: </strong>Retrospective cohort study.</p><p><strong>Subjects: </strong>NTG eyes having Hydrus with cataract surgery and cataract-only controls METHODS: Glaucoma was staged by the Hodapp-Parrish-Anderson criteria. Generalized estimating equations were used to account for intra-ocular correlation in regression analyses.</p><p><strong>Main outcome measures: </strong>The primary outcome was medication reduction from baseline at 1 year. Secondary outcomes were medication reduction in subsequent years, mean IOP change from baseline, proportion of eyes meeting IOP targets, and percentage of eyes requiring secondary surgical interventions (SSI) at yearly timepoints.</p><p><strong>Results: </strong>Sixty-four eyes of 40 patients undergoing Hydrus microstent and cataract surgery were included in the analysis, of which 32 eyes were from Asian patients. Thirty-nine eyes of 25 patients were used as cataract-only controls. Glaucoma severity was mild (37.5%), moderate (40.6%) and severe (21.9%) in treated eyes. The median follow-up available was 2.5 years (range: 1-5 years). Baseline IOP was 13.83±2.93 mmHg on 2.11±1.04 medication classes in treated eyes. At year 1, there was a mean reduction of medication classes by 1.25±0.84 (p < 0.0010) and IOP by 0.89±2.61 mmHg (p = 0.02). Medication class reduction remained significant through year 4 and IOP reduction through year 3. Compared to controls, treated eyes had significant differences in mean medication change (-1.25 vs -0.03 at year 1, p<0.001) and percentage of eyes with medication reduction (85.9% vs 5.3% at year 1, p<0.001), which were sustained through at least year 4. There were no significant differences in medication reduction and IOP observed between treated Asian and non-Asian eyes at any timepoint. In treated eyes, IOP was 16 mmHg or less on same or fewer medications in more than 90% (range: 90.6-100%) of eyes at all timepoints and medication free in more than 31% (range: 31.3-54.5%) at all timepoints. No SSI occurred during the study period.</p><p><strong>Conclusion: </strong>Hydrus Microstent was safe and effective in all NTG eyes with a significant, sustained reduction in medication use through at least 4 years of follow up.</p>","PeriodicalId":56368,"journal":{"name":"Ophthalmology. Glaucoma","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144327813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Female Authorship Trends in Ophthalmology Glaucoma.","authors":"Sophia S Lam, Tak Yee Tania Tai, Nisha Chadha","doi":"10.1016/j.ogla.2025.06.005","DOIUrl":"https://doi.org/10.1016/j.ogla.2025.06.005","url":null,"abstract":"<p><p>Retrospective cohort study of 364 original publications in Ophthalmology: Glaucoma from 2018 to 2024. Proportion of female senior authors increased over 6 years, mirroring the increase in female board-certified ophthalmologists but the gap between female and male representation remains.</p>","PeriodicalId":56368,"journal":{"name":"Ophthalmology. Glaucoma","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}