Fatma Hammami, Makram Koubaa, Amal Chakroun, Khaoula Rekik, Sonda Mezghani, Adnane Hammami, Chakib Marrakchi, Fatma Smaoui, Mounir Ben Jemaa
{"title":"A case series of Mediterranean spotted fever and murine typhus with neurological manifestations.","authors":"Fatma Hammami, Makram Koubaa, Amal Chakroun, Khaoula Rekik, Sonda Mezghani, Adnane Hammami, Chakib Marrakchi, Fatma Smaoui, Mounir Ben Jemaa","doi":"10.4103/0972-9062.383643","DOIUrl":"10.4103/0972-9062.383643","url":null,"abstract":"<p><strong>Background objectives: </strong>Severe cases with neurological manifestations of rickettsiosis have been reported. We aimed to identify the epidemiological, clinical and laboratory features of central nervous system rickettsial infections and to describe the treatment.</p><p><strong>Methods: </strong>We carried out a retrospective study that included all patients hospitalized with rickettsiosis in the infectious diseases department of Hedi Chaker University Hospital in Sfax, Tunisia between 1993 and 2018.</p><p><strong>Results: </strong>We identified 47 patients with central nervous system rickettsial infections among 440 patients with rickettsial infections (10.7%). Skin rash (31.9% vs 87.8%; p<0.001) and eschar (4.2% vs 27.7%; p<0.001) were less frequent among patients with central nervous system rickettsial infections. Complications (6.4% vs 0.5%; p=0.01) and death (4.2% vs 0.3%; p=0.03) were more frequent among patients with central nervous system rickettsial infections.</p><p><strong>Interpretation conclusion: </strong>Cardinal clinical features and typical laboratory results including thrombocytopenia were less frequent, and prognosis was more severe in patients with central nervous system rickettsial infections.</p>","PeriodicalId":56210,"journal":{"name":"Indian Journal of Dental Sciences","volume":"15 1","pages":"489-494"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45724038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francisco Martínez Martínez, Marta Belén Cabo-Pastor, Félix De Carlos-Villafranca, N. García-Carrillo, Vidushi Jindal, J. Calvo-Guirado
{"title":"Clinical Study of Analgesic and Anti-inflammatory Properties of Cannabis Derivatives in Patients with Temporomandibular Joint Pathology: Preliminary Study","authors":"Francisco Martínez Martínez, Marta Belén Cabo-Pastor, Félix De Carlos-Villafranca, N. García-Carrillo, Vidushi Jindal, J. Calvo-Guirado","doi":"10.4103/ijds.ijds_17_24","DOIUrl":"https://doi.org/10.4103/ijds.ijds_17_24","url":null,"abstract":"\u0000 We all know that the use of marijuana is a potent anti-inflammatory and analgesic and possible mechanisms of action and components that can help reduce the effects of pain in temporomandibular joint (TMJ) disorders. Our study aimed to analyze the anti-inflammatory and analgesic characteristics of cannabis derivatives in patients with temporomandibular pathology. Thirty-six patients were divided into three groups: one was treated with Cannabidiol (CBD) cream, the second was treated with CBD Vaper, and the third was treated with conventional anti-inflammatories such as Ibuprofen 600 mg. All patients underwent a dental computed tomography scan at the beginning and another at the end of treatment 28 days later. In addition to the study treatment of Cannabis and anti-inflammatories, all patients received physiotherapy treatment on day 0, day 14, day 21, and day 28 of the study. The study’s results allow us to evaluate that using the CBD cream with physiotherapy results in a favorable pain reduction of 59%, CBD Vaper with physiotherapy has reduced pain by 35%, and the combined use of ibuprofen medication with physiotherapy has reduced pain by 45%. Therefore, using CBD and physiotherapy allows a biological reduction of pain and inflammation at TMJ. The most significant reduction in analgesia and pain occurred with CBD cream, followed by ibuprofen, which had less effect than CBD Vaper. We can control the pain of the TMJ with the use of CBD and treatment with the physiotherapist that allows us to maintain the dose and time of use of CBD both in cream and in Vaper; this improves the quality of life and returns the patient to cognitive relieving stress and anxiety.","PeriodicalId":56210,"journal":{"name":"Indian Journal of Dental Sciences","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140716843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Seasonal prevalence of dengue vector mosquito <i>Aedes aegypti</i> Linn in Jaipur city, Rajasthan, India.","authors":"Neha Kumawat, Ramesh Prajapat, Pooja Meena, Shashi Meena","doi":"10.4103/0972-9062.383645","DOIUrl":"10.4103/0972-9062.383645","url":null,"abstract":"<p><strong>Background & objectives: </strong>Vector-borne diseases are a significant issue for public health worldwide, especially in India. In recent years, high number of dengue and chikungunya cases have been reported from Rajasthan state of India, those are principally transmitted by Aedes aegypti. These vectors are extremely intrusive and can thrive in practically any climate. However, vector mosquitos' prevalence in Jaipur district is not properly documented. Therefore, current research was carried out to ascertain the seasonal fluctuations of Aedes aegypti in Jaipur city, Rajasthan, India.</p><p><strong>Methods: </strong>In order to ascertain the seasonal variation, monitoring of Aedes mosquitoes was conducted from August 2021 to July 2022 at nine selected regions in the Jaipur city. The breeding capacity of vectors was evaluated using three vector indices: the House Index, Breteau Index, and Container Index.</p><p><strong>Results: </strong>A total of 2172 out of 6336 breeding sites and 3735 out of 7477 containers were found positive for Aedes species. Three important species of Aedes vectors were collected in which Aedes aegypti was reported as the most prevalent. The highest values for House Index (57.60%) and Container Index (54.95%) were observed in October and the least rate was observed in March.</p><p><strong>Interpretation & conclusion: </strong>This survey was carried out to investigate the seasonal prevalence of dengue vectors and the findings revealed seasonal fluctuations in the indices of Aedes reproducing potential. This calls for precautionary actions to avoid infection rates and epidemic emergence. Therefore, to stop epidemics and eradicate vector-borne infections, the current study recommends close monitoring and further vector management efforts.</p>","PeriodicalId":56210,"journal":{"name":"Indian Journal of Dental Sciences","volume":"15 1","pages":"421-426"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44251370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Piyali Dey, Santa Mandal, Danswrang Goyary, Anurag Verma
{"title":"Larvicidal property and active compound profiling of <i>Annona squamosa</i> leaf extracts against two species of diptera, <i>Aedes aegypti</i> and <i>Anopheles stephensi</i>.","authors":"Piyali Dey, Santa Mandal, Danswrang Goyary, Anurag Verma","doi":"10.4103/0972-9062.383647","DOIUrl":"10.4103/0972-9062.383647","url":null,"abstract":"<p><strong>Background & objectives: </strong>Vector control measures are important in lowering the spread of infections spread by mosquito. Synthetic pesticides used to suppress vector populations during the larval stage have had adverse impacts on people and the environment. The early III instar larvae of Aedes aegypti and Anopheles stephensi were the targets of the current experiment, which assessed the larvicidal ability of petroleum ether, chloroform, methanol, and aqueous extracts of Annona squamosa leaves.</p><p><strong>Methods: </strong>Using the standard World Health Organization (WHO) larval bioassay test, leaf extracts were evaluated for their activity against Ae. aegypti and An. stephensi to determine lethal doses. Phytochemical analysis and gas chromatography-mass spectrometry (GC-MS) were carried out to identify larvicidal components in the extract. Further analysis using a scanning electron microscope (SEM) was done to check the extracts toxicity for both mosquito larvae.</p><p><strong>Results: </strong>The larvicidal active components were identified by GC-MS as tetradecanoic acid, cis-vaccenic acid, and 2,4-di-tert-butylphenol etc. Methanol leaf extracts of A. squamosa (ASME) exhibited strong larvicidal activity against the early 3<sup>rd</sup> instar larvae of Ae. aegypti and An. stephensi with Lethal concentration (LC<sub>50</sub>) values of 51.450 ppm and 107.121 ppm. Cell damages to the larva post exposure to ASME were examined.</p><p><strong>Interpretation & conclusion: </strong>This finding showed that the ASME has better larvicidal activity and its components that may be used to kill larvae as larvicides. The extracts toxicity towards damage of midgut of larva further suggests that this plant methanol leaf extracts could be effective in larval growth control approaches.</p>","PeriodicalId":56210,"journal":{"name":"Indian Journal of Dental Sciences","volume":"15 1","pages":"401-413"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46337327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jyotsna S Shah, Joseph J Burrascano, Ranjan Ramasamy
{"title":"Recombinant protein immunoblots for differential diagnosis of tick-borne relapsing fever and Lyme disease.","authors":"Jyotsna S Shah, Joseph J Burrascano, Ranjan Ramasamy","doi":"10.4103/0972-9062.383641","DOIUrl":"10.4103/0972-9062.383641","url":null,"abstract":"<p><p>Lyme disease (LD) is caused by a group of tick-borne bacteria of the genus Borrelia termed Lyme disease Borreliae (LDB). The detection of serum antibodies to specific LDB antigens is widely used to support diagnosis of LD. Recent findings highlight a need for serological tests that can differentiate LD from tick-borne relapsing fever (TBRF) caused by a separate group of Borrelia species termed relapsing fever Borreliae. This is because LD and TBRF share some clinical symptoms and can occur in overlapping locations. The development of serological tests for TBRF is at an early stage compared with LD. This article reviews the application of line immunoblots (IBs), where recombinant proteins applied as lines on nitrocellulose membrane strips are used to detect antibodies in patient sera, for the diagnosis and differentiation of LD and TBRF.</p>","PeriodicalId":56210,"journal":{"name":"Indian Journal of Dental Sciences","volume":"15 1","pages":"353-364"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44692898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessment of eruption disturbances in the mixed dentition phase of a population in Eastern India: A cross-sectional study","authors":"N. Saha, Shiladitya Sil, Subhankar Ghosh","doi":"10.4103/ijds.ijds_34_23","DOIUrl":"https://doi.org/10.4103/ijds.ijds_34_23","url":null,"abstract":"Context: Eruption disturbances in the primary dentition resulting from environmental and genetic factors can eventually lead to complex anomalies in permanent dentition. If intercepted at an early stage, such anomalies in the permanent dentition can be averted. Aim: In this study, the most common eruption disturbances in the mixed dentition phase have been highlighted in an ethnic group in Eastern India. Materials and Methods: Three thousand children between the ages of 6 and 12 years were randomly chosen with 1330 children in the experimental group and 1670 in the control group. The entire population was divided into two age groups – 6–9 years and 10–12 years. The experimental group had 680 males and 650 females. A total of nine parameters were identified that included premature loss of deciduous teeth, over-retained primary teeth, supernumerary teeth, congenital absence of permanent teeth, ankylosis, eruption cysts, etc., Statistical Analysis Used: The Chi-square test was used for the analysis. Results: Statistically significant differences were observed for each of the parameters considered in this study with respect to the two age groups, namely 6–9 years and 10–12 years, and gender, namely male and female, of the experimental group with P < 0.01%. Conclusion: Accurate understanding of the pattern of eruption disturbances in the mixed dentition period of any ethnic group and/or population is imperative for timely intervention and/or referral by primary care dentists so that malocclusion in the permanent dentition can be intercepted and corrected, thereby improving the quality of life index for that ethnic group/population.","PeriodicalId":56210,"journal":{"name":"Indian Journal of Dental Sciences","volume":"15 1","pages":"144 - 150"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45011614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diode laser-assisted bridge flap","authors":"Shrutikirti Gupta, Neelam Das, Suruchi, Shashwat Pratik","doi":"10.4103/ijds.ijds_22_22","DOIUrl":"https://doi.org/10.4103/ijds.ijds_22_22","url":null,"abstract":"Mucogingival problems are associated with recession of gingival margin, shallow vestibular depth, and gingival margin pull by aberrant frenum. Till now, various individualistic and successful surgical techniques have been described in the literature for mucogingival problems. These case series enumerate the gingival recession cases, managed by bridge flap technique using diode laser which is a single-step procedure to cover the earlier exposed root surfaces and extend the width of the attached gingiva. Postsurgical parameters were recorded at 6 months and 1 year.","PeriodicalId":56210,"journal":{"name":"Indian Journal of Dental Sciences","volume":"15 1","pages":"160 - 162"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45944663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shivani Singh, B. Saraf, N. Sheoran, Ritu Singh, D. Kapil
{"title":"Knowledge, attitude, and practice of parents about child's oral health in Faridabad and its correlation with prevalence of dental caries in children through a questionnaire survey","authors":"Shivani Singh, B. Saraf, N. Sheoran, Ritu Singh, D. Kapil","doi":"10.4103/ijds.ijds_63_22","DOIUrl":"https://doi.org/10.4103/ijds.ijds_63_22","url":null,"abstract":"Background: An individual's health and overall well-being are strongly correlated with their oral health. Parents' knowledge, attitude, and practice have a great impact on the maintenance of child's oral health. Objective and Aim: The aim of the study is to assess the knowledge, attitude, and practice of parents about child's oral health in Faridabad and its correlation with prevalence of dental caries in children through a questionnaire survey in 3–6-year-old children. Materials and Methods: A cross-sectional study was conducted in Faridabad. The data were collected from the parents and their children 3–6 years old. A total sample of 400 parents and their children 3–6 years old residing in Faridabad was included. A questionnaire regarding knowledge, attitude, and practice about child's oral health was given to the parents. The parents who volunteer to participate in the study their children were taken for the study examination. Results: Parental perception of early childhood oral health is critical for developing effective preventive measures. Parents play an important role in making decisions about their child's oral health. The parents were given a self-administered questionnaire. The study included 400 parents and children aged 3–6 years. There was no significant difference in perception of their child's oral health care between mothers and fathers. The majority of parents/caretakers had good knowledge about children's oral hygiene, particularly fathers, but this knowledge did not appear to reflect in their attitude and practice. Conclusion: The current study concludes that parents are not well aware about dental disease prevention measures. As a result, it is the responsibility of the government and health-care providers to teach parents about oral health because they are role models for their children.","PeriodicalId":56210,"journal":{"name":"Indian Journal of Dental Sciences","volume":"15 1","pages":"151 - 156"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41597502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An in vitro comparative evaluation of the fracture resistance of teeth with mesio-occluso-distal preparations restored with different esthetic materials by bulk-fill and incremental methods","authors":"Shefali Goyal, Monika Choudhary, Neetu Jindal, Renu Aggarwal","doi":"10.4103/ijds.ijds_129_22","DOIUrl":"https://doi.org/10.4103/ijds.ijds_129_22","url":null,"abstract":"Introduction: One of the most popular restorative materials today is resin-based composite. Volumetric shrinkage is brought on by polymerization, which can cause contraction stress, microleakage, and adhesion failure. Adhesive restorations have several benefits, including the ability to preserve more healthy tissue and “reinforce” the remaining tooth structure. These benefits go beyond just being attractive. Materials and Methods: Eighty extracted human maxillary premolars were entrenched in a self-cured acrylic resin in a rubber mold cylinder (2.5 cm width-3 cm height). These were arbitrarily divided into 5 groups: 2 control groups (positive control group and negative control group) (n = 10) and 3 experimental (n = 20) groups (microhybrid composite, nanocomposite, and Giomer). The mesio-occluso-distal (MOD) cavities were prepared in 70 samples. After MOD cavities preparation, groups were further subdivided into two subgroups for bulk-fill and incremental methods. Universal Tofflemire Retainer and band were placed on the prepared cavities. The self-etch adhesive was applied on all aspects of the preparations and then it was light-cured using a light-curing unit for 15 s. Now, cavities were restored with different esthetic materials and methods. In the bulk-fill method, the MOD cavity was restored with a solitary increase of restorative material and light cured from all directions of tooth for 20 s each. In the incremental technique, the proximal box on both sides was reconstructed first in a gradual manner, in which two oblique increments and one horizontal increment were restored and treated for 20 s. Then, two oblique increments of material were used to reestablish the occlusal component, and it was once more light-cured for 20 s. Fracture resistance was checked using a steel bar with a diameter of 4.5 mm that was positioned in the middle of the occlusal surface and a crosshead speed of 3 mm/min, all of the samples were compressed axially loaded. Results: The fracture resistance of microhybrid composite resins in bulk technique was significantly higher than that of nanocomposites and Giomer. However, the fracture resistance of nanocomposite in the incremental method was significantly higher than the other two restorative materials. Conclusion: The quality of restoration depends both on the material and method used during the restoration procedure. Both factors are dependent on each other. Superior fracture resistance was shown by microhybrid composites when restored with the bulk-fill technique and nanohybrid composites when restored with the incremental technique.","PeriodicalId":56210,"journal":{"name":"Indian Journal of Dental Sciences","volume":"15 1","pages":"130 - 135"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47966662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Student-led seminars as an enforcement-learning method for human anatomy – Dentistry students' perspectives","authors":"Poonam Patnaik, D. Singh","doi":"10.4103/0972-9062.383651","DOIUrl":"https://doi.org/10.4103/0972-9062.383651","url":null,"abstract":"Background: The “student led seminar (SLS)” is one in which students prepare and present selected topics through multi-source research with the assistance and guidance of the faculty. Teamwork is increasingly emphasized in health care, and team training is now considered to be essential in medical education. Small group learning promotes active learning and develops communication and teamwork skills. It also improves problem-solving skills, attitudes, and the development of interpersonal skills. Aim of the Study: The aim of this study was to evaluate the efficacy of SLSs as a teaching-learning method for Bachelor of Dental Surgery undergraduates through students' perception. Methodology: This was a prospective, observational study conducted for 5 months among 1st year dentistry students. The students were divided in small groups and the topics for the seminar were allocated for presentation according to the roster. Each group was given 20 min for presentation, 10 min for question time and discussion. A hard copy of the slides presented was also collected. Feedback was taken on pretested questionnaire containing 11 Likert-based items on a five-point scale. Descriptive statistics were applied for each item question. Cronbach's alpha test was applied to check the internal validity of the questionnaire. Satisfaction rate and index were calculated. Fischer's exact test was applied to find the odds ratio of satisfaction rate between male verses female students and hosteller verses day scholar students for each item question separately. Student's t-test was applied to determine the difference in the performance of students in the first and second internal assessments at P = 0.05 significance level. Results: Among the participants, 32 were female (mean age 19 ± 1.46) and 18 were male (mean age 20 ± 1.82) students. Ninety-five percent of students agreed that the seminars improved their self-confidence and enhanced their presentation skills, helped them acquire a deeper understanding of the topic, an opportunity to use resources (time, electronic gadgets, and media) responsibly, even outside the bounds of the lecture theatre. Overall, mean score on Likert scale was 3.9 ± 0.307. The satisfaction rate and index were the highest for question 3. The second term examination result showed statistically significant improvement over that of the 1st term. Conclusions: The student seminar is a potentially important resource of the teaching-learning method that has yet to be fully implemented and therefore needs to be incorporated into the medical curriculum on a regular basis.","PeriodicalId":56210,"journal":{"name":"Indian Journal of Dental Sciences","volume":"15 1","pages":"136 - 143"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44169015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}