Canadian Journal of Anesthesia-Journal Canadien D Anesthesie最新文献

{"title":"A \"Train of Four\" iPhone application to enhance the utility of peripheral nerve stimulators.","authors":"Ratan K Banik, Kiichi Takeuchi, Michael M Todd","doi":"10.1007/s12630-026-03108-4","DOIUrl":"https://doi.org/10.1007/s12630-026-03108-4","url":null,"abstract":"","PeriodicalId":56145,"journal":{"name":"Canadian Journal of Anesthesia-Journal Canadien D Anesthesie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147790420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differential effects of phenylephrine on brain versus skeletal muscle microvascular perfusion: an in vivo laboratory study using translational rodent models.","authors":"Helen Jiang, Kyle Chin, Timothy H Mak, S F Michelle Ku, Sami I Alissa, Albert K Y Tsui, Elaine Liu, Nikhil Mistry, Talin Boghosian T, Sebastian Swic, David F Wilson, Sergei A Vinogradov, James L Mahoney, Bijan Teja, Ahmad Alli, Andrew J Baker, C David Mazer, Gregory M T Hare, Melinda A Musgrave","doi":"10.1007/s12630-026-03101-x","DOIUrl":"https://doi.org/10.1007/s12630-026-03101-x","url":null,"abstract":"<p><strong>Purpose: </strong>Hypotension, or low mean arterial blood pressure (MAP), has been associated with adverse outcomes in perioperative patients. A primary goal of treating hypotension during surgery is to preserve vital organ perfusion by maintaining intravascular volume and the use of vasoactive medications, including phenylephrine (PE), to support MAP. Phenylephrine, a vasoconstrictor with α₁-adrenergic agonist activity, acts on resistance arterioles and veins to increase vascular resistance and reduce venous capacitance, thereby increasing MAP. It predominantly acts on skeletal muscle resistance arterioles, but concerns have been raised about its potential negative impact on brain and revascularized muscle flap perfusion.</p><p><strong>Methods: </strong>We conducted an in vivo animal study using translational rodent models. Measuring microvascular blood flow (laser Doppler) and partial pressure of oxygen (PO₂) (phosphorescence quenching of oxygen) in rats (total N = 48), we sought to test the hypothesis that PE produces differential effects on brain, skeletal muscle, and skeletal muscle flap perfusion.</p><p><strong>Results: </strong>Treatment of hypotension with PE increased MAP, brain microvascular blood flow, and brain tissue PO₂, at the expense of reduced skeletal muscle microvascular blood flow. Escalating doses of PE reduced skeletal muscle microvascular blood flow without reducing tissue PO₂. Tissue blood flow and PO₂ were severely reduced in skeletal muscle free flaps at baseline, without any further reduction after exposure to escalating doses of PE. Elevation of the hypoxic cellular protein hypoxia-inducible factor 1α (HIF-1α) in muscle free flaps provided evidence of severe tissue hypoxia in viable muscle flap tissue.</p><p><strong>Conclusions: </strong>These data may inform the optimal use of PE to restore MAP to ensure optimal brain tissue perfusion. Use of tissue oximetry may ensure the adequacy of tissue perfusion in perioperative patients.</p>","PeriodicalId":56145,"journal":{"name":"Canadian Journal of Anesthesia-Journal Canadien D Anesthesie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147790413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In reply: Comment on: \"Dexmedetomidine in pediatric tonsillectomy: a systematic review with meta-analysis\".","authors":"Julia M Olsen, Kazuyoshi Aoyama","doi":"10.1007/s12630-026-03105-7","DOIUrl":"https://doi.org/10.1007/s12630-026-03105-7","url":null,"abstract":"","PeriodicalId":56145,"journal":{"name":"Canadian Journal of Anesthesia-Journal Canadien D Anesthesie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147790403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Energy cost and emission savings from overnight ultrasound power-down in regional anesthesia.","authors":"Edward Umberto Serghi, Jessica Hammal, Elizabeth Fouts-Palmer, Tareq Salah, Deirdre Kelleher, Vivian H Y Ip","doi":"10.1007/s12630-026-03106-6","DOIUrl":"https://doi.org/10.1007/s12630-026-03106-6","url":null,"abstract":"","PeriodicalId":56145,"journal":{"name":"Canadian Journal of Anesthesia-Journal Canadien D Anesthesie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147790383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reflections on learning about artificial intelligence as a clinician.","authors":"Urooj Siddiqui","doi":"10.1007/s12630-026-03109-3","DOIUrl":"https://doi.org/10.1007/s12630-026-03109-3","url":null,"abstract":"","PeriodicalId":56145,"journal":{"name":"Canadian Journal of Anesthesia-Journal Canadien D Anesthesie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147700778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feeling like a fraud or made to feel like one? Rethinking imposter syndrome in anesthesiology.","authors":"Mia Gisselbaek, Kori A LaDonna","doi":"10.1007/s12630-026-03095-6","DOIUrl":"https://doi.org/10.1007/s12630-026-03095-6","url":null,"abstract":"","PeriodicalId":56145,"journal":{"name":"Canadian Journal of Anesthesia-Journal Canadien D Anesthesie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147655472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing support for family physician anesthetists in Canada.","authors":"Beverley A Orser, Jason McVicar, Nadia Alam","doi":"10.1007/s12630-026-03094-7","DOIUrl":"https://doi.org/10.1007/s12630-026-03094-7","url":null,"abstract":"","PeriodicalId":56145,"journal":{"name":"Canadian Journal of Anesthesia-Journal Canadien D Anesthesie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147655477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anesthesiologist-led surgical progressive care unit in Winnipeg, Manitoba, Canada.","authors":"Kate Ross-Hopley, Thomas Mutter, Manpreet Bhangu, Peter Inglis","doi":"10.1007/s12630-026-03090-x","DOIUrl":"https://doi.org/10.1007/s12630-026-03090-x","url":null,"abstract":"","PeriodicalId":56145,"journal":{"name":"Canadian Journal of Anesthesia-Journal Canadien D Anesthesie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147610845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The prevalence and characteristics of imposter syndrome among anesthesiology staff and trainees in British Columbia, Canada: an online survey study.","authors":"Nancy Wang, Nicholas C West, McKenna Postles, Lynnie R Correll","doi":"10.1007/s12630-026-03083-w","DOIUrl":"10.1007/s12630-026-03083-w","url":null,"abstract":"","PeriodicalId":56145,"journal":{"name":"Canadian Journal of Anesthesia-Journal Canadien D Anesthesie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147476214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of indirect versus direct laryngoscopes for nasotracheal intubation in adults undergoing elective surgery: a systematic review and network meta-analysis.","authors":"Hiroshi Hoshijima, Takahiro Mihara, Toshiya Shiga, Kentaro Mizuta","doi":"10.1007/s12630-026-03087-6","DOIUrl":"10.1007/s12630-026-03087-6","url":null,"abstract":"<p><strong>Purpose: </strong>It is not clear whether indirect laryngoscopes are superior to direct laryngoscopes for nasotracheal intubation and which laryngoscopes are better for nasotracheal intubation. We sought to undertake a ranking of the effectiveness of intubation devices in patients undergoing nasotracheal intubation.</p><p><strong>Methods: </strong>We conducted a systematic review and network meta-analysis (NMA). We searched electronic databases for prospective randomized studies comparing different tracheal intubation devices in patients undergoing nasotracheal intubation. The primary outcome was intubation time. The secondary outcomes were first-attempt success rate, glottic visualization, use of Magill forceps, and the use of external laryngeal manipulation. We used DerSimonian and Laird random-effects models for statistical analysis. We performed frequentist network meta-analysis and generated network plots and network league tables.</p><p><strong>Results: </strong>We included 22 studies comparing 10 types of devices. With the Macintosh direct laryngoscope as reference, six indirect laryngoscopes significantly reduced intubation time relative to the Macintosh laryngoscope. In the ranking of intubation time, the C-MAC® D-Blade (Karl Storz SE & Co. KG, Tuttlingen, Germany) had the highest P-score (0.98), and the Macintosh blade had the lowest P-score (0.07). In terms of first-attempt success rate, the C-MAC D-Blade had the highest (P-score, 0.78) and the Airway Scope™ S100 (Nihon Koden, Tokyo, Japan) the lowest (P-score, 0.06). Regarding glottic visualization, the Truview EVO2 (Truphatek International, Netanya, Israel) achieved the highest P-score (0.79), while the McCoy laryngoscope (Penlon, Abingdon, UK) had the lowest P-score (0.05).</p><p><strong>Conclusions: </strong>In the present NMA to establish a ranking of the effectiveness of intubation devices in patients undergoing nasotracheal intubation, we found that most indirect laryngoscopes likely reduced intubation time, increased first-attempt success rates, and were more effective tracheal intubation devices for nasotracheal intubation compared with direct laryngoscopes The findings of the present a systematic review and NMA support a recommendation for the use of indirect laryngoscopes for nasotracheal intubation (very low certainty of evidence).</p><p><strong>Study registration: </strong>PROSPERO ( CRD42023446646 ); first submitted 20 July 2023.</p>","PeriodicalId":56145,"journal":{"name":"Canadian Journal of Anesthesia-Journal Canadien D Anesthesie","volume":" ","pages":"147-158"},"PeriodicalIF":3.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13121532/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147517107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}