Eunicia Ursu, Ana Mikolić, Bobo Tong, Noah D Silverberg, Nishtha Parag, Denise Foster, Mypinder S Sekhon, William Panenka, Sonny Thiara, Donald E G Griesdale
{"title":"Functional outcomes among the survivors of veno-venous extracorporeal membrane oxygenation during the COVID-19 pandemic: a historical cohort study.","authors":"Eunicia Ursu, Ana Mikolić, Bobo Tong, Noah D Silverberg, Nishtha Parag, Denise Foster, Mypinder S Sekhon, William Panenka, Sonny Thiara, Donald E G Griesdale","doi":"10.1007/s12630-025-02965-9","DOIUrl":"https://doi.org/10.1007/s12630-025-02965-9","url":null,"abstract":"<p><strong>Purpose: </strong>Veno-venous extracorporeal membrane oxygenation (VV-ECMO) is increasingly being used in patients with respiratory failure. The goal of this study was to characterize postdischarge psychological and functional outcomes of this patient population.</p><p><strong>Methods: </strong>We conducted a historical cohort study of survivors who required VV-ECMO during the COVID-19 pandemic. Using telephone interviews, we assessed the following domains: disability (using the World Health Organization Disability Schedule [WHODAS 2.0] and modified Rankin Scale [mRS]), health-related quality of life (using the European Quality of Life 5 Dimensions 5 Level tool), cognition (using the telephone Montreal Cognitive Assessment tool), depression (using the Patient Health Questionnaire-9), and posttraumatic stress disorder symptoms (using the Impact of Event Scale-6). We used descriptive statistics to analyze our results.</p><p><strong>Results: </strong>Twenty-six participants with a median [interquartile range (IQR)] age of 47 [42-59] yr and 6 (23%) of whom were female were evaluated at a median [IQR] of 22 [17-23] months after ECMO separation. Twenty-two (85%) had a diagnosis of COVID-19. The median [IQR] WHODAS 2.0 score was 26 [15-30] with the highest degree of disability in the mobility and participation domains. Of the 24 participants who were employed full-time, 12 (50%) were able to work in the same capacity. Of the 25 respondents who were living independently at baseline, 22 (88%) maintained complete independence for their activities of daily living (mRS < 3), one (4%) described persistent functional limitations (mRS = 3), and two (8%) required constant care (mRS = 4 or 5). Thirteen (52%) and nine (38%) reported at least moderate pain or anxiety, respectively. Ten (40%) and seven (28%) participants screened positive for symptoms of depression or posttraumatic stress disorder, respectively.</p><p><strong>Conclusions: </strong>Patients who required VV-ECMO experienced significant functional disability, pain, cognitive challenges, mental health problems, and lower quality of life approximately two years after discharge.</p>","PeriodicalId":56145,"journal":{"name":"Canadian Journal of Anesthesia-Journal Canadien D Anesthesie","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144183161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amina Omari, Sheidai Salim, Simon Ponthus, Lionel Dumont
{"title":"Resourcefulness in anesthesia: overcoming absurd limitations in pediatric induction in sub-Saharan Africa.","authors":"Amina Omari, Sheidai Salim, Simon Ponthus, Lionel Dumont","doi":"10.1007/s12630-025-02968-6","DOIUrl":"https://doi.org/10.1007/s12630-025-02968-6","url":null,"abstract":"","PeriodicalId":56145,"journal":{"name":"Canadian Journal of Anesthesia-Journal Canadien D Anesthesie","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"New evidence amid old assumptions for thromboembolic risk after total knee arthroplasty: a twist in the story.","authors":"Derek Dillane, Colleen Harnett","doi":"10.1007/s12630-025-02958-8","DOIUrl":"https://doi.org/10.1007/s12630-025-02958-8","url":null,"abstract":"","PeriodicalId":56145,"journal":{"name":"Canadian Journal of Anesthesia-Journal Canadien D Anesthesie","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on: Channelled versus nonchannelled Macintosh videolaryngoscope blades in patients with a cervical collar: a randomized controlled noninferiority trial.","authors":"Atsushi Kobayashi, Shingo Kawashima, Tetsuro Kimura, Hiroyuki Kinoshita","doi":"10.1007/s12630-025-02969-5","DOIUrl":"https://doi.org/10.1007/s12630-025-02969-5","url":null,"abstract":"","PeriodicalId":56145,"journal":{"name":"Canadian Journal of Anesthesia-Journal Canadien D Anesthesie","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In reply: Comment on: Channelled versus nonchannelled Macintosh videolaryngoscope blades in patients with a cervical collar: a randomized controlled noninferiority trial.","authors":"Kyung Won Shin, Hyongmin Oh","doi":"10.1007/s12630-025-02970-y","DOIUrl":"https://doi.org/10.1007/s12630-025-02970-y","url":null,"abstract":"","PeriodicalId":56145,"journal":{"name":"Canadian Journal of Anesthesia-Journal Canadien D Anesthesie","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nanbo Luo, Li Luo, Lei Yang, Zhi Li, Qingmin Yu, Wenling Jian, Wei Sun, Pac-Soo Chen, Qian Chen, Daqing Ma, Qingsheng Xue, Yan Luo, Buwei Yu, Hao Wang, Zhiheng Liu
{"title":"Association between general anesthesia combined with peripheral nerve blocks versus neuraxial anesthesia without nerve blocks for high-risk isolated distal deep venous thrombosis in patients undergoing knee arthroplasty: a historical cohort study.","authors":"Nanbo Luo, Li Luo, Lei Yang, Zhi Li, Qingmin Yu, Wenling Jian, Wei Sun, Pac-Soo Chen, Qian Chen, Daqing Ma, Qingsheng Xue, Yan Luo, Buwei Yu, Hao Wang, Zhiheng Liu","doi":"10.1007/s12630-025-02957-9","DOIUrl":"https://doi.org/10.1007/s12630-025-02957-9","url":null,"abstract":"<p><strong>Purpose: </strong>General anesthesia combined with peripheral nerve blocks has become a common anesthesia regimen for knee replacement surgery. Its association with high-risk isolated distal deep venous thrombosis (IDDVT) remains uncertain.</p><p><strong>Methods: </strong>In this cohort study, we obtained consecutive data from the electronic inpatient records of Shenzhen Second People's Hospital, including adults who underwent knee arthroplasty from 1 September 2019 to 31 August 2021. The primary outcome was the incidence of high-risk IDDVT. We compared the outcomes in patients who received general anesthesia combined with nerve blocks with those in patients who received neuraxial anesthesia without nerve blocks, using a multivariable regression model with inverse probability weighting according to the propensity score.</p><p><strong>Results: </strong>Of the 848 patients who underwent knee arthroplasty, 330 were excluded because they lacked thrombus testing or had received other types of anesthesia. Of the remaining 518 patients, 267/518 (52%) received general anesthesia combined with nerve blocks and 251/518 (48%) received neuraxial anesthesia with no nerve blocks. A total of 99 patients developed high-risk IDDVT. In the primary multivariable analysis with inverse probability weighting according to the propensity score, general anesthesia combined with nerve blocks was associated with a significantly reduced high-risk IDDVT compared with neuraxial anesthesia without nerve blocks (odds ratio, 0.50; 95% confidence interval, 0.31 to 0.81; P = 0.005). The results of multiple sensitivity analyses were similar between the two cohorts. E-value analysis suggested robustness to unmeasured confounding.</p><p><strong>Conclusions: </strong>Compared with neuraxial anesthesia without peripheral nerve blocks, general anesthesia combined with peripheral nerve blocks in patients undergoing knee arthroplasty was associated with a reduced incidence of high-risk IDDVT in our retrospective study. A large multicentre prospective clinical trial is needed to validate our findings.</p><p><strong>Study registration: </strong>ChiCTR.org.cn ( ChiCTR2200057006 ), first submitted 25 February 2022.</p>","PeriodicalId":56145,"journal":{"name":"Canadian Journal of Anesthesia-Journal Canadien D Anesthesie","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jean-Pierre Lecoq, Annalinda Ciorra, Marie Renard, Alain Carlier, Pierre Bonnet, Jean-François Fils, Vincent Bonhomme, Emmanuel Guntz
{"title":"Brachial plexus block at the level of the humeral head: a proof-of-concept observational cadaver and clinical study.","authors":"Jean-Pierre Lecoq, Annalinda Ciorra, Marie Renard, Alain Carlier, Pierre Bonnet, Jean-François Fils, Vincent Bonhomme, Emmanuel Guntz","doi":"10.1007/s12630-025-02962-y","DOIUrl":"https://doi.org/10.1007/s12630-025-02962-y","url":null,"abstract":"","PeriodicalId":56145,"journal":{"name":"Canadian Journal of Anesthesia-Journal Canadien D Anesthesie","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144129526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ben T Chen, Wendy H C Song, Anthony Chau, Su-Yin MacDonell
{"title":"The magnitude and impact of noise on patient care in a tertiary postanesthesia care unit: an observational study and survey of nursing perspectives.","authors":"Ben T Chen, Wendy H C Song, Anthony Chau, Su-Yin MacDonell","doi":"10.1007/s12630-025-02963-x","DOIUrl":"https://doi.org/10.1007/s12630-025-02963-x","url":null,"abstract":"","PeriodicalId":56145,"journal":{"name":"Canadian Journal of Anesthesia-Journal Canadien D Anesthesie","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144112901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Conall Francoeur, Laura Hornby, Anab Lehr, Ahmed Alkharusi, J Gordon Boyd, Christine Saint Martin, Chantal Poulin, Fiona Slater, Matthew P Kirschen, Sam D Shemie
{"title":"Hypoxic-ischemic spinal cord injury following resuscitated cardiac arrest: a case series and rapid literature review.","authors":"Conall Francoeur, Laura Hornby, Anab Lehr, Ahmed Alkharusi, J Gordon Boyd, Christine Saint Martin, Chantal Poulin, Fiona Slater, Matthew P Kirschen, Sam D Shemie","doi":"10.1007/s12630-025-02937-z","DOIUrl":"https://doi.org/10.1007/s12630-025-02937-z","url":null,"abstract":"<p><strong>Purpose: </strong>Cardiac arrest can cause hypoxic-ischemic injury and result in both spinal cord injury and death determination by neurologic criteria (DNC). The presence and severity of hypoxic-ischemic spinal cord injury (HISCI) impacts neuro-prognostication, rehabilitation, and may confound DNC evaluation in patients by interfering with motor responses and respiratory muscle function in apnea testing. We describe five children with postarrest HISCI detected on magnetic resonance imaging (MRI) and supplement our observations with a literature review.</p><p><strong>Clinical features: </strong>Postarrest HISCI was identified in five consecutive pediatric cases of prolonged cardiac arrest and hypoxic-ischemic brain injury in a single centre. All patients had cardiopulmonary resuscitation for > 30 min and resultant severe hypoxic-ischemic brain injury. Spinal MRI indications were loss of rectal tone (n = 3), focal deficit (n = 1), and practice change related to recent cases (n = 1). A rapid review of the literature yielded case reports, case series, and retrospective reviews describing 90 patients (81 adults; nine pediatric) with postarrest HISCI. Ischemia distribution was variable, most frequently reported at the cervical and thoracic levels, although some patients had ischemia of the entire cord. Paraplegia was the most common deficit among survivors. There were no reports of HISCI in patients who underwent assessment for DNC.</p><p><strong>Conclusions: </strong>This case series and rapid literature review highlights that both adults and children may be at risk of HISCI after prolonged cardiac arrest. Our findings suggest that further research should focus on determining the incidence and sequelae of HISCI after resuscitated cardiac arrest, as well as evaluating its potential impact on DNC practice and neuro-prognostication.</p>","PeriodicalId":56145,"journal":{"name":"Canadian Journal of Anesthesia-Journal Canadien D Anesthesie","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144112896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical features and airway management experience in an infant with Arboleda-Tham syndrome.","authors":"Kumi Kataoka, Igor Luginbuehl","doi":"10.1007/s12630-025-02966-8","DOIUrl":"https://doi.org/10.1007/s12630-025-02966-8","url":null,"abstract":"","PeriodicalId":56145,"journal":{"name":"Canadian Journal of Anesthesia-Journal Canadien D Anesthesie","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144112859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}