Sophie Arheix-Parras, Mathilde du Puy de Goyne, Julie Franco, Marie Villain, Bertrand Glize , Grégoire Python
{"title":"Transcranial magnetic stimulation to improve aphasia after right hemispheric stroke: A single case experimental design","authors":"Sophie Arheix-Parras, Mathilde du Puy de Goyne, Julie Franco, Marie Villain, Bertrand Glize , Grégoire Python","doi":"10.1016/j.rehab.2024.101858","DOIUrl":"https://doi.org/10.1016/j.rehab.2024.101858","url":null,"abstract":"","PeriodicalId":56030,"journal":{"name":"Annals of Physical and Rehabilitation Medicine","volume":"67 6","pages":"Article 101858"},"PeriodicalIF":4.6,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141250649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hongji Zeng , Xi Zeng , Nanxi Liu , Yu Ding , Junfa Wu , Fangquan Zhang , Nana Xiong
{"title":"Development and validation of a nomogram for tracheotomy decannulation in individuals in a persistent vegetative state: A multicentre study","authors":"Hongji Zeng , Xi Zeng , Nanxi Liu , Yu Ding , Junfa Wu , Fangquan Zhang , Nana Xiong","doi":"10.1016/j.rehab.2024.101849","DOIUrl":"10.1016/j.rehab.2024.101849","url":null,"abstract":"<div><h3>Background</h3><p>Decannulation for people in a persistent vegetative state (PVS) is challenging and relevant predictors of successful decannulation have yet to be identified.</p></div><div><h3>Objective</h3><p>This study aimed to explore the predictors of tracheostomy decannulation outcomes in individuals in PVS and to develop a nomogram.</p></div><div><h3>Method</h3><p>In 2022, 872 people with tracheostomy in PVS were retrospectively enrolled and their data was randomly divided into a training set and a validation set in a 7:3 ratio. Univariate and multivariate regression analyses were performed on the training set to explore the influencing factors for decannulation and nomogram development. Internal validation was performed using 5-fold cross-validation. External validation was performed using receiver operating characteristic (ROC) curves, calibration curves, and decision curve analysis (DCA) on both the training and validation sets.</p></div><div><h3>Result</h3><p>Data from 610 to 262 individuals were used for the training and validation sets, respectively. The multivariate regression analysis found that duration of tracheostomy tube placement≥30 days (Odds Ratio [OR] 0.216, 95 % CI 0.151–0.310), pulmonary infection (OR 0.528, 95 %CI 0.366–0.761), hypoproteinemia (OR 0.669, 95 % CI 0.463–0.967), no passive standing training (OR 0.372, 95 % CI 0.253–0.547), abnormal swallowing reflex (OR 0.276, 95 % CI 0.116–0.656), mechanical ventilation (OR 0.658, 95 % CI 0.461–0.940), intensive care unit (ICU) duration>4 weeks (OR 0.517, 95 % CI 0.332–0.805), duration of endotracheal tube (OR 0.855, 95 % CI 0.803–0.907), older age (OR 0.981, 95 % CI 0.966–0.996) were risk factors for decannulation failure. Conversely, peroral feeding (OR 1.684, 95 % CI 1.178–2.406), passive standing training≥60 min (OR 1.687, 95 % CI 1.072–2.656), private caregiver (OR 1.944, 95 % CI 1.350–2.799) and ICU duration<2 weeks (OR 1.758, 95 % CI 1.173–2.634) were protective factors conducive to successful decannulation. The 5-fold cross-validation revealed a mean area under the curve of 0.744. The ROC curve C-indexes for the training and validation sets were 0.784 and 0.768, respectively, and the model exhibited good stability and accuracy. The DCA revealed a net benefit when the risk threshold was between 0 and 0.4.</p></div><div><h3>Conclusion</h3><p>The nomogram can help adjust the treatment and reduce decannulation failure.</p></div><div><h3>Registration</h3><p>Clinical registration is not mandatory for retrospective studies.</p></div>","PeriodicalId":56030,"journal":{"name":"Annals of Physical and Rehabilitation Medicine","volume":"67 6","pages":"Article 101849"},"PeriodicalIF":4.6,"publicationDate":"2024-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141238709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chia-Ying Lai , Chia-Huei Lin , Ta-Chung Chao , Chueh-Ho Lin , Cheng-Chiang Chang , Chien-Yao Huang , Shang-Lin Chiang
{"title":"Effectiveness of a 12-week telerehabilitation training in people with long COVID: A randomized controlled trial","authors":"Chia-Ying Lai , Chia-Huei Lin , Ta-Chung Chao , Chueh-Ho Lin , Cheng-Chiang Chang , Chien-Yao Huang , Shang-Lin Chiang","doi":"10.1016/j.rehab.2024.101853","DOIUrl":"10.1016/j.rehab.2024.101853","url":null,"abstract":"<div><h3>Background</h3><p>Telerehabilitation has been developed and applied for years for cardiac and pulmonary diseases with good clinical outcomes. However, its application to participants with long COVID remains limited.</p></div><div><h3>Objectives</h3><p>To investigate the effectiveness of a 12-week telerehabilitation training program in participants with long COVID. The primary outcome was cardiorespiratory fitness (CRF), and secondary outcomes were physical activity (PA) amounts, exercise self-efficacy, sleep quality, and health-related quality of life (HRQOL).</p></div><div><h3>Methods</h3><p>A parallel-group, randomized controlled trial was conducted. Eligible participants with long COVID (<em>n</em> = 182) were randomly assigned in a 1:1 ratio to either the experimental group (EG) or the control group (CG). The EG received 12 weeks of telerehabilitation training with weekly remote monitoring for exercise maintenance and support. The CG received PA counseling only. CRF, PA amounts, exercise self-efficacy, sleep quality, and HRQOL were assessed at baseline and 12 weeks. Generalized estimating equations were used to analyze the intervention effects by examining the interaction between time and group.</p></div><div><h3>Results</h3><p>One hundred twenty-two participants (67 %) completed the study, and 182 were included in the intention-to-treat analysis. The EG had greater walking behavior (β = –763.3, <em>p</em> < 0.001), total amount of PA (β= –711, <em>p</em> = 0.003), exercise self-efficacy (β = –1.19, <em>p</em> < 0.001), and better sleep quality (β = 1.69, <em>p</em> = 0.012) after the 12-weeks of telerehabilitation training than the CG. However, there were no significant differences in any CRF parameters or HRQOL at 12 weeks between the EG and CG.</p></div><div><h3>Conclusion</h3><p>Telerehabilitation training offers a personalized and convenient approach that can increase exercise willingness and PA amounts and improve sleep quality. These findings underscore the potential benefits of telerehabilitation training for promoting healthier lifestyles and improving overall health outcomes.</p></div><div><h3>Clinical Trial Registration</h3><p>The study was registered at ClinicalTrials.gov (NCT05205460) on January 25, 2022.</p></div>","PeriodicalId":56030,"journal":{"name":"Annals of Physical and Rehabilitation Medicine","volume":"67 5","pages":"Article 101853"},"PeriodicalIF":4.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141201204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hugo Bessaguet , Paul Calmels , Alexis Schnitzler , Flavia Coroian , Pascal Giraux , Florence Angioni , Ahmed Adham , Philippe Denormandie , Romain David , Etienne Ojardias
{"title":"Percutaneous needle tenotomies: indications, procedures, efficacy and safety. A systematic review","authors":"Hugo Bessaguet , Paul Calmels , Alexis Schnitzler , Flavia Coroian , Pascal Giraux , Florence Angioni , Ahmed Adham , Philippe Denormandie , Romain David , Etienne Ojardias","doi":"10.1016/j.rehab.2024.101839","DOIUrl":"10.1016/j.rehab.2024.101839","url":null,"abstract":"<div><h3>Background</h3><p>Percutaneous needle tenotomies constitute a promising approach that enables direct access to tendons through minimally invasive interventions. They can be performed rapidly without need for large incisions or general anaesthesia. However, the reported procedures are heterogeneous and currently conducted without guidelines.</p></div><div><h3>Objectives</h3><p>We aimed to determine the indications for percutaneous needle tenotomies described in the current literature. Our secondary aim was to identify the different procedures reported, as well as their efficacy and their safety.</p></div><div><h3>Methods</h3><p>A systematic review following PRISMA guidelines was conducted to identify original articles that mentioned percutaneous needle tenotomy in humans and reported its application, description, effectiveness or adverse events. Non-percutaneous tendinous surgical procedures and ineligible designs were excluded. The Downs and Black checklist was used to assess the risk of bias.</p></div><div><h3>Results</h3><p>A total of 540 studies were identified from the MEDLINE, Embase, Cochrane Library, and PEDro databases. Fourteen clinical studies met the inclusion criteria and were found to have an acceptable quality (674 individuals, 1664 tenotomies). Our results indicated a wide variety of indications for percutaneous needle tenotomies in children and in adults. We highlighted 24 tendons as eligible targets in the upper and lower limbs. Tenotomies were performed with either 16- or 18-Ga needles, lasted from 1 to 30 min, and were performed using various procedures. Their efficacy was mainly assessed through clinical outcomes highlighting tendon discontinuity on palpation after the procedure. Passive range-of-motion gains after tenotomy were reported for both upper and lower limbs with an estimated 5 % complication rate.</p></div><div><h3>Conclusion</h3><p>This is the first review to systematically synthesize all the available evidence on the indications, procedures, efficacy and safety of percutaneous tenotomies exclusively performed with needles. Current evidence suggests that procedures are safe and effective for treating various deformities.</p></div><div><h3>PROSPERO registration</h3><p>CRD42022350571</p></div>","PeriodicalId":56030,"journal":{"name":"Annals of Physical and Rehabilitation Medicine","volume":"67 5","pages":"Article 101839"},"PeriodicalIF":4.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S187706572400023X/pdfft?md5=9976ccc5bda6621b49faee6dff6c3cef&pid=1-s2.0-S187706572400023X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141201260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Louis Jacob , Sandra Lasbleiz , Katherine Sanchez , Odile Morchoisne , Marie-Martine Lefèvre-Colau , Christelle Nguyen , François Rannou , Antoine Feydy , Jean-Jacques Portal , Alexis Schnitzler , Eric Vicaut , Jean-Denis Laredo , Pascal Richette , Philippe Orcel , Johann Beaudreuil
{"title":"Arthro-distension with early and intensive mobilization for shoulder adhesive capsulitis: A randomized controlled trial","authors":"Louis Jacob , Sandra Lasbleiz , Katherine Sanchez , Odile Morchoisne , Marie-Martine Lefèvre-Colau , Christelle Nguyen , François Rannou , Antoine Feydy , Jean-Jacques Portal , Alexis Schnitzler , Eric Vicaut , Jean-Denis Laredo , Pascal Richette , Philippe Orcel , Johann Beaudreuil","doi":"10.1016/j.rehab.2024.101852","DOIUrl":"10.1016/j.rehab.2024.101852","url":null,"abstract":"<div><h3>Background</h3><p>There are several therapeutic options for the management of shoulder adhesive capsulitis (AC). The superiority of arthro-distension over intra-articular steroid injection (ISI) for AC remains controversial.</p></div><div><h3>Objectives</h3><p>To evaluate the efficacy of a single arthro-distension procedure combined with early and intensive mobilization (ADM) and physiotherapy, versus ISI and physiotherapy, in people with AC lasting ≥3 months.</p></div><div><h3>Methods</h3><p>This was a prospective, 2 parallel-group, 2-center, observer-blind randomized controlled trial conducted in tertiary care settings. Adults with AC were randomly assigned to the treatment or control group. Efficacy was assessed using the self-administered Shoulder Pain and Disability Index (SPADI). Total, pain and disability SPADI scores 15 days, 6 weeks, and 3, 6 and 12 months after the procedure (total SPADI at 15 days: primary outcome; other outcomes were secondary) were compared between groups using analysis of covariance (ANCOVA). A post hoc analysis stratified on the initial range of passive glenohumeral abduction, which had not been pre-specified, was conducted.</p></div><div><h3>Results</h3><p>There were 33 participants in each group. Both groups improved over time. Mean (SD) total SPADI score at 15 days was 33.8 (19.6) in the treatment group and 32.8 (17.5) in the control group, <em>p</em> = 0.393. There were no significant differences for any variables in the overall sample. The post hoc analysis found ADM to be associated with a significant decrease in total SPADI score at 15 days compared with ISI (<em>p</em> = 0.049) in individuals with initial passive glenohumeral abduction >45°.</p></div><div><h3>Conclusions</h3><p>The effects of ADM on pain and function were not statistically different from those of ISI. However, ADM may be useful in individuals with initial passive glenohumeral abduction >45°.</p></div><div><h3>Database registration</h3><p>NCT00724113.</p></div>","PeriodicalId":56030,"journal":{"name":"Annals of Physical and Rehabilitation Medicine","volume":"67 6","pages":"Article 101852"},"PeriodicalIF":4.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141201274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Danielle M.F. Driessen , Cecile M.A. Utens , Prof Gerard M. Ribbers , Willemijn S. van Erp , Majanka H. Heijenbrok-Kal
{"title":"Short-term outcomes of early intensive neurorehabilitation for prolonged disorders of consciousness: A prospective cohort study","authors":"Danielle M.F. Driessen , Cecile M.A. Utens , Prof Gerard M. Ribbers , Willemijn S. van Erp , Majanka H. Heijenbrok-Kal","doi":"10.1016/j.rehab.2024.101838","DOIUrl":"10.1016/j.rehab.2024.101838","url":null,"abstract":"<div><h3>Background</h3><p>Advances in medical care have increased survival in people with severe brain injuries and with that the number of survivors with prolonged disorders of consciousness (PDOC) has increased. In the literature, early intensive neurorehabilitation (EIN) for people with PDOC is recommended to achieve the best possible outcomes.</p></div><div><h3>Objectives</h3><p>To evaluate the frequency and extent of recovery of consciousness, mortality, complications, pain and discomfort, and medication during a nationwide EIN programme in people with PDOC after acquired brain injury. We hypothesized that level of consciousness would improve in half of people with PDOC.</p></div><div><h3>Methods</h3><p>Prospective cohort study. People with PDOC aged 16 years and older admitted to the EIN department centralized in a single rehabilitation centre in the Netherlands (Libra Rehabilitation & Audiology) were included. The EIN delivers a subacute medical level of care and rehabilitation for a maximum duration of 14 weeks. The outcome measures were level of consciousness (CRS-R), mortality, number of complications, medication and pain/discomfort (NCS-R).</p></div><div><h3>Results</h3><p>Of the 104 people included, 68 % emerged to a minimal conscious state with command-following or higher during EIN and 44 % regained consciousness. Mortality during EIN was 6 %, and 50 % of deaths followed a non-treatment decision or withdrawal of life-sustaining treatment. Almost all participants had at least 1 medical complication, leading to hospital readmission for 30 %. 73 % showed no pain or discomfort. During EIN, cardiovascular medication and analgesics were reduced by 15 %.</p></div><div><h3>Conclusions</h3><p>During the EIN programme, a large percentage of people with PDOC regained at least a minimal conscious state or even consciousness. These outcomes and the frequent medical complications in these people suggest that intensive specialized care should be offered to all people with PDOC. The outcomes of this study might help health professionals to better inform the families of people with PDOC about the short-term prognosis of PDOC.</p></div><div><h3>Protocol registration number</h3><p>The Dutch Trial Register, NL 8138.</p></div>","PeriodicalId":56030,"journal":{"name":"Annals of Physical and Rehabilitation Medicine","volume":"67 5","pages":"Article 101838"},"PeriodicalIF":4.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1877065724000228/pdfft?md5=de5d87e145adac27fce69b1eab0c5a99&pid=1-s2.0-S1877065724000228-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141238704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrew L. Alejo, Alexander S. Rascoe, Chang-Yeon Kim, Bryan O. Ren, Matthew T. Hoffa, Isabella M. Heimke, Heather A. Vallier
{"title":"Factors associated with a prolonged time to return to safe driving following lower extremity injuries","authors":"Andrew L. Alejo, Alexander S. Rascoe, Chang-Yeon Kim, Bryan O. Ren, Matthew T. Hoffa, Isabella M. Heimke, Heather A. Vallier","doi":"10.1016/j.rehab.2024.101850","DOIUrl":"10.1016/j.rehab.2024.101850","url":null,"abstract":"","PeriodicalId":56030,"journal":{"name":"Annals of Physical and Rehabilitation Medicine","volume":"67 6","pages":"Article 101850"},"PeriodicalIF":4.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141201275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A systematic review of rehabilitation programs for cognitive impairment related to breast cancer: Different programs at different times?","authors":"Marianne Merceur , Karen T. Reilly , Isabelle Bonan , Julie Holé , Emilie Hummel , Mélanie Cogné , Sophie Jacquin-Courtois","doi":"10.1016/j.rehab.2024.101832","DOIUrl":"https://doi.org/10.1016/j.rehab.2024.101832","url":null,"abstract":"<div><h3>Background</h3><p>“Cancer Related Cognitive Impairment” (CRCI) defines cognitive disorders related to cancer and its treatments. Many people with breast cancer experience signs of CRCI (incidence between 20 and 30 %) and, although several intervention options exist, there is no established standard of care. Our main objective was to provide a detailed description of the methods and results of randomized controlled trials of interventions for CRCI in breast cancer survivors, paying particular attention to the timing of the interventions within the care pathway.</p></div><div><h3>Methods</h3><p>We conducted a systematic literature review following the PRISMA guidelines from 01 to 01–2019 to 16–07–2023 and included randomized controlled trials of interventions for CRCI after breast cancer with at least one objective cognitive assessment as a primary or secondary outcome.</p></div><div><h3>Results</h3><p>Among 228 identified studies, 35 (including 2821 participants) were retained for inclusion. The interventions were classified into 4 categories: cognitive rehabilitation, physical activity, complementary therapy and pharmacological treatment. Our analysis revealed that pharmacological interventions have no effect, whereas physical activity interventions proposed in the months following the initial cancer treatment improve Quality of Life and Speed of Information Processing while interventions proposed later improve Memory and Attention (Cognitive Rehabilitation) and Perceived Cognitive Function and Depression/Anxiety/Mood (Complementary Therapies).</p></div><div><h3>Conclusion</h3><p>CRCI is multifactorial and affected individuals frequently experience high levels of fatigue, pain, anxiety and depression and are most likely to benefit from holistic approaches that include cognition, physical activity, relaxation, psychoeducation, group support and/or psychological counselling. Thus, rehabilitation programs should be designed on multi-modal approaches, using innovative, cost-effective delivery methods that increase access to treatment, and intervention outcomes should be evaluated using measures of participation.</p></div><div><h3>Database registration</h3><p>The review was recorded on Prospero (01–03–2020), with the registration number 135,627.</p></div>","PeriodicalId":56030,"journal":{"name":"Annals of Physical and Rehabilitation Medicine","volume":"67 5","pages":"Article 101832"},"PeriodicalIF":4.6,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1877065724000162/pdfft?md5=d4662c4398d05033f335e59950f52ebb&pid=1-s2.0-S1877065724000162-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140296521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marina G. Downing , Meagan Carty , John Olver , Michael Ponsford , Rose Acher , Dean Mckenzie , Jennie L. Ponsford
{"title":"The impact of age on outcome 2 years after traumatic brain injury: Case control study","authors":"Marina G. Downing , Meagan Carty , John Olver , Michael Ponsford , Rose Acher , Dean Mckenzie , Jennie L. Ponsford","doi":"10.1016/j.rehab.2024.101834","DOIUrl":"https://doi.org/10.1016/j.rehab.2024.101834","url":null,"abstract":"<div><h3>Background</h3><p>Age is associated with outcome after traumatic brain injury (TBI). However, there are mixed findings across outcome domains and most studies lack controls.</p></div><div><h3>Objectives</h3><p>This cross-sectional study examined the association between age group (15–24 years, 25–34 years, 35–44 years, 45–54 years, 55–64 years, and 65 years or more) and outcomes 2 years after TBI in independence in daily activities, driving, public transportation use, employment, leisure activities, social integration, relationships and emotional functioning, relative to healthy controls. It was hypothesized that older individuals with TBI would have significantly poorer outcomes than controls in all domains except anxiety and depression, for which it was expected they would show better outcomes. Global functional outcome (measured using the Glasgow Outcome Scale-Extended) was also examined, and we hypothesized that older adults would have poorer outcomes than younger adults.</p></div><div><h3>Methods</h3><p>Participants were 1897 individuals with TBI (mean, SD age 36.7, 17.7 years) who completed measures 2 years post-injury and 110 healthy controls (age 38.3, 17.5 years).</p></div><div><h3>Results</h3><p>Compared to controls, individuals with TBI were less independent in most activities of daily living, participated less in leisure activities and employment, and were more socially isolated, anxious and depressed (<em>p</em> < 0.001). Those who were older in age were disproportionately less likely to be independent in light domestic activities, shopping and driving; and participated less in occupational activities relative to controls. Functional outcome was significantly higher in the youngest age group than in all older age groups (<em>p</em> < 0.001), but the younger groups were more likely to report being socially isolated (<em>p</em> < 0.001), depressed (<em>p</em> = 0.005) and anxious (<em>p</em> = 0.02), and less likely to be married or in a relationship (<em>p</em> < 0.001).</p></div><div><h3>Conclusion</h3><p>A greater focus is needed on addressing psychosocial issues in younger individuals with TBI, whereas those who are older may require more intensive therapy to maximise independence in activities of daily living and return to employment.</p></div>","PeriodicalId":56030,"journal":{"name":"Annals of Physical and Rehabilitation Medicine","volume":"67 5","pages":"Article 101834"},"PeriodicalIF":4.6,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1877065724000186/pdfft?md5=ca499dba63496fb2be178e29ae1429c0&pid=1-s2.0-S1877065724000186-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140180483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}