Blood Pressure最新文献

{"title":"The INTERSALT Study and the complex relationship between salt intake and blood pressure","authors":"S. Kjeldsen, K. Narkiewicz, M. Burnier, S. Oparil","doi":"10.1080/08037051.2016.1274957","DOIUrl":"https://doi.org/10.1080/08037051.2016.1274957","url":null,"abstract":"The Global Burden of Disease Study 2015 [1] reported that the five largest contributors to global disability-adjusted life years (DALYs) among diseases, injuries and risk factors were high systolic...","PeriodicalId":55591,"journal":{"name":"Blood Pressure","volume":"26 1","pages":"65 - 66"},"PeriodicalIF":1.8,"publicationDate":"2017-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/08037051.2016.1274957","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47849813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Global Burden of Disease Study 2015 and Blood Pressure","authors":"S. Kjeldsen, K. Narkiewicz, M. Burnier, S. Oparil","doi":"10.1080/08037051.2016.1267557","DOIUrl":"https://doi.org/10.1080/08037051.2016.1267557","url":null,"abstract":"The Global Burden of Disease Study 2015[1] reported that the five largest contributors to global disability-adjusted life-years (DALYs) among diseases, injuries and risk factors were high systolic blood pressure (212 million with 95% Confidence Intervals (CIs) 193–231 million), smoking (149 with 95% CIs 134–163 million), high fasting plasma glucose (143 with 95% CIs 125–164 million), high body mass index (120 million with 95% CIs 84–158 million) and childhood undernutrition (113 million with 95% CIs 104–123 million). High total cholesterol, alcohol use and diets high in sodium were also listed among the top 10 risk factors. Interestingly, in 1990, childhood undernutrition, unsafe water and high systolic blood pressure were the three leading risk factors for attributable DALYs. Of these, only high systolic blood pressure continued to be ranked among the three leading risk factors in 2015. The Global Burden of Disease report concludes that achievement of optimal blood pressure in the population would yield large potential gains in global health and that study of blood pressure in people younger than 60 years of age is an important area for future investigation. A wide array of clinical and population strategies are available to reduce systolic blood pressure, including improving nutrition, increasing physical activity, reducing or slowing the rise of high body mass index, and in many countries providing access to effective anti-hypertensive medications. We believe that the Global Burden of Disease Study is the most useful global effort to inform governments, health care providers and the population at large of the real issues of risk factors, diseases and injuries in the world and the most important global study to reveal that hypertension has remained the leading risk factor for disease and death worldwide for the past quarter century. Blood Pressure is making an important contribution for elucidating the global problem of hypertension by publishing a wide array of research from around the world, as reflected by the papers in the current issue. Disclosure statement","PeriodicalId":55591,"journal":{"name":"Blood Pressure","volume":"26 1","pages":"1 - 1"},"PeriodicalIF":1.8,"publicationDate":"2017-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/08037051.2016.1267557","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44531966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors associated with diagnostic discrepancy for left ventricular hypertrophy between electrocardiography and echocardiography","authors":"Søren Sandager Petersen, Line Reinholdt Pedersen, M. Pareek, M. L. Nielsen, S. Diederichsen, M. Leósdóttir, P. Nilsson, A. Diederichsen, M. Olsen","doi":"10.1080/08037051.2016.1235959","DOIUrl":"https://doi.org/10.1080/08037051.2016.1235959","url":null,"abstract":"Abstract Objective: To investigate the influence of cardiovascular risk factors, including fasting plasma glucose (FPG), on the association between electrocardiographic (ECG) and echocardiographic left ventricular hypertrophy (LVH) in an elderly population. Methods: We tested cross-sectional associations between electrocardiographic and echocardiographic LVH, defining LVH according to the Sokolow-Lyon voltage combination, Cornell voltage-duration product, or left ventricular mass index (LVMI). Differences between standardized LVMI and Sokolow-Lyon voltage combination or Cornell voltage-duration product (absolute value/cut-off value for LVH) were used as outcome variables in order to identify explanatory variables associated with diagnostic discrepancies between ECG and echocardiography. Results: Of the 1382 subjects included, 77% did not display any signs of LVH, 6% had LVH defined by ECG only, 13% had LVH defined by echocardiography only, and 5% had LVH on both ECG and echocardiography. Older subjects and those with higher blood pressure and RWT were more likely to have a relatively greater LVMI on echocardiography than that predicted on ECG (odds ratio: 1.65 per 10 years (95% confidence interval (CI): 1.27-2.15), p = .0002, odds ratio: 1.17 per 10 mmHg (95% CI: 1.09-1.25), p < .0001, and odds ratio: 1.21 per 0.10 (95% CI: 1.02-1.42), p = .03). In addition, discrepancy was also seen in females and subjects receiving antihypertensive medication (odds ratio: 1.41 (95% CI: 1.04-1.89), p = .03 and odds ratio: 1.41 (95% CI: 1.06-1.87), p = .02), but FPG did not independently influence discrepancy between ECG and echocardiography. Conclusion: Age, blood pressure, female sex, greater RWT and use of antihypertensive medication were associated with a greater risk of non-consistency between LVH determined by ECG and echocardiography.","PeriodicalId":55591,"journal":{"name":"Blood Pressure","volume":"26 1","pages":"54 - 63"},"PeriodicalIF":1.8,"publicationDate":"2017-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/08037051.2016.1235959","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44673242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum","authors":"","doi":"10.1080/08037051.2016.1243366","DOIUrl":"https://doi.org/10.1080/08037051.2016.1243366","url":null,"abstract":"","PeriodicalId":55591,"journal":{"name":"Blood Pressure","volume":"26 1","pages":"i - i"},"PeriodicalIF":1.8,"publicationDate":"2017-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/08037051.2016.1243366","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47683290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum","authors":"","doi":"10.1080/14017431.2016.1256051","DOIUrl":"https://doi.org/10.1080/14017431.2016.1256051","url":null,"abstract":"","PeriodicalId":55591,"journal":{"name":"Blood Pressure","volume":"26 1","pages":"ii - ii"},"PeriodicalIF":1.8,"publicationDate":"2017-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/14017431.2016.1256051","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44949945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship of diastolic function to new or persistent electrocardiographic left ventricular hypertrophy.","authors":"Michael T Tanoue,&nbsp;Sverre E Kjeldsen,&nbsp;Richard B Devereux,&nbsp;Peter M Okin","doi":"10.1080/08037051.2016.1179514","DOIUrl":"https://doi.org/10.1080/08037051.2016.1179514","url":null,"abstract":"<p><strong>Background: </strong>Persistence or development of Cornell product left ventricular hypertrophy (LVH) is associated with increased heart failure (HF) risk that is partly explained by greater LV systolic dysfunction. However, whether new or persistent Cornell product LVH during antihypertensive treatment is associated with worse LV diastolic function is unclear.</p><p><strong>Methods: </strong>Left ventricular diastolic function was examined in relation to year-3 ECG LVH in 377 hypertensive patients with a preserved LV ejection fraction (>45%) at year-3. Cornell product >2440 mm·ms defined ECG LVH.</p><p><strong>Results: </strong>In multivariate models adjusting for age, sex, change from baseline to year-3 systolic blood pressure, and baseline and change from baseline to year-3 Sokolow-Lyon voltage, persistent or new Cornell product LVH at year-3 remained associated with year-3 abnormal half filling time (OR 1.63, 95% CI 1.04-2.55 p = 0.034), with a trend toward higher odds of abnormal third filling time (OR 1.51, 95% CI 0.087 p = 0.087) and total filling time (OR 1.79, CI 0.98-3.27 p = 0.059).</p><p><strong>Conclusion: </strong>In hypertensive patients undergoing antihypertensive therapy, persistence or development of Cornell product ECG LVH at year-3 follow-up is modestly associated with LV diastolic dysfunction. These findings suggest that diastolic dysfunction may be a mechanism via which changing ECG LVH influences HF risk.</p>","PeriodicalId":55591,"journal":{"name":"Blood Pressure","volume":"25 6","pages":"364-372"},"PeriodicalIF":1.8,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/08037051.2016.1179514","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34454492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypertension is strongly associated with false-positive bicycle exercise stress echocardiography testing results.","authors":"Karsten Keller,&nbsp;Kathrin Stelzer,&nbsp;Thomas Munzel,&nbsp;Mir Abolfazl Ostad","doi":"10.1080/08037051.2016.1182419","DOIUrl":"https://doi.org/10.1080/08037051.2016.1182419","url":null,"abstract":"<p><strong>Introduction: </strong>Exercise echocardiography is a reliable routine test in patients with known or suspected coronary artery disease. However, in ∼15% of all patients, stress echocardiography leads to false-positive stress echocardiography results. We aimed to investigate the impact of hypertension on stress echocardiographic results.</p><p><strong>Methods: </strong>We performed a retrospective study of patients with suspected or known stable coronary artery disease who underwent a bicycle exercise stress echocardiography. Patients with false-positive stress results were compared with those with appropriate results.</p><p><strong>Results: </strong>126 patients with suspected or known coronary artery disease were included in this retrospective study. 23 patients showed false-positive stress echocardiography results. Beside comparable age, gender distribution and coronary artery status, hypertension was more prevalent in patients with false-positive stress results (95.7% vs. 67.0%, p = 0.0410). Exercise peak load revealed a borderline-significance with lower loads in patients with false-positive results (100.0 (IQR 75.0/137.5) vs. 125.0 (100.0/150.0) W, p = 0.0601). Patients with false-positive stress results showed higher systolic (2.05 ± 0.69 vs. 1.67 ± 0.39 mmHg/W, p = 0.0193) and diastolic (1.03 ± 0.38 vs. 0.80 ± 0.28 mmHg/W, p = 0.0165) peak blood pressure (BP) per wattage. In a multivariate logistic regression test, hypertension (OR 17.6 [CI 95% 1.9-162.2], p = 0.0115), and systolic (OR 4.12 [1.56-10.89], p = 0.00430) and diastolic (OR 13.74 [2.46-76.83], p = 0.00285) peak BP per wattage, were associated with false-positive exercise results. ROC analysis for systolic and diastolic peak BP levels per wattage showed optimal cut-off values of 1.935mmHg/W and 0.823mmHg/W, indicating false-positive exercise echocardiographic results with AUCs of 0.660 and 0.664, respectively.</p><p><strong>Conclusions: </strong>Hypertension is a risk factor for false-positive stress exercise echocardiographic results in patients with known or suspected coronary artery disease. Presence of hypertension was associated with 17.6-fold elevated risk of false-positive results.</p>","PeriodicalId":55591,"journal":{"name":"Blood Pressure","volume":"25 6","pages":"351-359"},"PeriodicalIF":1.8,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/08037051.2016.1182419","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34470562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of social class on the amount of salt intake in patients with hypertension.","authors":"Seyed Saeed Mazloomy Mahmoodabad,&nbsp;Hadi Tehrani,&nbsp;Mahdi Gholian-Aval,&nbsp;Hasan Gholami,&nbsp;Mohsen Nematy","doi":"10.1080/08037051.2016.1179508","DOIUrl":"https://doi.org/10.1080/08037051.2016.1179508","url":null,"abstract":"<p><p>Reducing salt intake is a factor related to life style which can influence the prevention of blood pressure. This study was conducted to assess the impact of social class on the amount of salt intake in patients with hypertension in Iran. This was an observational on the intake of salt, as estimated by Kawasaki formula in a sample from Iranian population, stratified for social background characteristics. The finding in general was that the estimated salt intake was somewhat higher in subjects from a lower social background, while the opposite was true for lipid levels (LDL and HDL cholesterol). There was also a significant correlation between salt intake and the level of systolic blood pressure, but not the level of diastolic blood pressure. Considering high salt intake (almost double the standard amount in Iran), especially in patients with low-social class and the effects of salt on human health, it is suggested to design and perform suitable educational programs based on theories and models of health education in order to reduce salt intake.</p>","PeriodicalId":55591,"journal":{"name":"Blood Pressure","volume":"25 6","pages":"360-363"},"PeriodicalIF":1.8,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/08037051.2016.1179508","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34372099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Blood Pressure in 2016: increased impact factor and change of editors.","authors":"Sverre E Kjeldsen,&nbsp;Krzysztof Narkiewicz,&nbsp;Suzanne Oparil","doi":"10.1080/08037051.2016.1225493","DOIUrl":"https://doi.org/10.1080/08037051.2016.1225493","url":null,"abstract":"","PeriodicalId":55591,"journal":{"name":"Blood Pressure","volume":"25 6","pages":"331-332"},"PeriodicalIF":1.8,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/08037051.2016.1225493","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34719284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of antihypertensive treatment with lercanidipine on endothelial progenitor cells and inflammation in patients with mild to moderate essential hypertension.","authors":"Carolina De Ciuceis,&nbsp;Claudia Rossini,&nbsp;Angela Tincani,&nbsp;Paolo Airò,&nbsp;Mirco Scarsi,&nbsp;Claudia Agabiti-Rosei,&nbsp;Giuseppina Ruggeri,&nbsp;Luigi Caimi,&nbsp;Doris Ricotta,&nbsp;Enrico Agabiti-Rosei,&nbsp;Damiano Rizzoni","doi":"10.1080/08037051.2016.1184495","DOIUrl":"https://doi.org/10.1080/08037051.2016.1184495","url":null,"abstract":"<p><strong>Background: </strong>It has been demonstrated that circulating endothelial progenitor cells (EPCs) number reflects the endogenous vascular repair ability, with the EPCs pool declining in presence of cardiovascular risk factors. Several drugs, including dihydropyridine calcium channel blockers, have been reported to elicit antioxidant and anti-inflammatory properties, as well as to improve vascular remodeling and dysfunction. However, no data are available about the effects of lercanidipine on EPCs. The aim of the present study was therefore to investigate the effects of short-term treatment with lercanidipine on circulating EPCs, as well as on indices of inflammation and oxidative stress.</p><p><strong>Patients and methods: </strong>Twenty essential hypertensive patients were included in the study and treated for 4 weeks with lercanidipine 20 mg per day orally. Investigations were performed in basal condition, after appropriate wash out of previous treatments, and after 4 weeks of lercanidipine treatment. Inflammatory and oxidative stress markers were assessed by ELISA technique. Lin-/7AAD-/CD34+/CD133+/VEGFR-2 + and Lin-/7AAD-/CD34+/VEGFR-2 + cells were identified by flow cytometry and considered as EPCs. EPCs cells were expressed as number of cells per million Lin-mononuclear cells.</p><p><strong>Results: </strong>Circulating EPCs were significantly increased after lercanidipine treatment (CD34+/CD133+/VEGFR-2 + cells: 78.3 ± 64.5 vs 46.6 ± 32.8; CD34+/VEGFR-2+: 87996 ± 165116 vs 1026 ± 1559, respectively, p < 0.05). A modest reduction in circulating indices of inflammation was also observed.</p><p><strong>Conclusions: </strong>In conclusion, lercanidipine is able to increase the number of circulating EPCs, possibly through a reduction of low-grade inflammation.</p>","PeriodicalId":55591,"journal":{"name":"Blood Pressure","volume":"25 6","pages":"337-343"},"PeriodicalIF":1.8,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/08037051.2016.1184495","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34562387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}