{"title":"Administration of medicines to children: a practical guide.","authors":"Lucinda Smith, Catherine Leggett, Corey Borg","doi":"10.18773/austprescr.2022.067","DOIUrl":"https://doi.org/10.18773/austprescr.2022.067","url":null,"abstract":"<p><p>Getting children to take medicines can be difficult. There is no 'one-size-fits-all' approach. When selecting medicines for children, it is important to consider the child's age, swallowing ability, ease of administration and accessibility of the product. Ask the child, parent or caregiver about their preference for formulations and flavours. There are different ways to alter the taste, aftertaste and mouth feel of medicines, which may help improve palatability. Pharmacists or medicines information services can assist with advice on suitable formulations or methods of administration.</p>","PeriodicalId":55588,"journal":{"name":"Australian Prescriber","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/1d/ac/austprescr-45-188.PMC9722353.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10740665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Australian PrescriberPub Date : 2022-12-01Epub Date: 2022-11-30DOI: 10.18773/austprescr.2022.065
Natalie Montarello, Wai Ping Alicia Chan
{"title":"Coronary artery disease in women.","authors":"Natalie Montarello, Wai Ping Alicia Chan","doi":"10.18773/austprescr.2022.065","DOIUrl":"10.18773/austprescr.2022.065","url":null,"abstract":"<p><p>Cardiovascular disease is the leading global cause of death in women but remains underdiagnosed and undertreated. Health professionals play an important role in improving the heart health of Australian women. Routine heart health checks should be offered to all women 45 years of age and older and to all Aboriginal and Torres Strait Islander women 30 years of age and older. Cardiovascular risk assessment in women must include traditional and sex-specific risk factors, including their pregnancy history and early-onset menopause. Women with pregnancy-related hypertensive and metabolic disorders have an increased long-term cardiovascular risk and require close monitoring. Women with acute coronary syndrome may not experience classical chest pain. More often, they experience cardiovascular events in the absence of obstructive coronary disease and have poorer cardiovascular outcomes. The recognition of sex-specific differences and more sex-specific trials are key to improving clinical outcomes.</p>","PeriodicalId":55588,"journal":{"name":"Australian Prescriber","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/25/5c/austprescr-45-193.PMC9722351.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10740667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Australian PrescriberPub Date : 2022-10-01Epub Date: 2022-09-01DOI: 10.18773/austprescr.2022.058
{"title":"Tixagevimab and cilgavimab for COVID-19 prophylaxis.","authors":"","doi":"10.18773/austprescr.2022.058","DOIUrl":"https://doi.org/10.18773/austprescr.2022.058","url":null,"abstract":"","PeriodicalId":55588,"journal":{"name":"Australian Prescriber","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/1b/15/austprescr-45-182.PMC9584788.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40688202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Australian PrescriberPub Date : 2022-10-01Epub Date: 2022-09-01DOI: 10.18773/austprescr.2022.060
{"title":"Diroximel fumarate for multiple sclerosis.","authors":"","doi":"10.18773/austprescr.2022.060","DOIUrl":"https://doi.org/10.18773/austprescr.2022.060","url":null,"abstract":"Diroximel fumarate is another molecule that is rapidly hydrolysed to monomethyl fumarate after oral administration. Although food reduces the maximum concentration, capsules of diroximel fumarate can be taken with or without food. Most of the twicedaily dose is expired as carbon dioxide. No dose adjustments are recommended for patients with renal or hepatic impairment. Pharmacokinetic drug interactions are unlikely.","PeriodicalId":55588,"journal":{"name":"Australian Prescriber","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b3/9b/austprescr-45-180.PMC9584786.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40688210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Australian PrescriberPub Date : 2022-10-01Epub Date: 2022-08-18DOI: 10.18773/austprescr.2022.055
{"title":"Erratum: Approach to the diagnosis of secondary hypertension in adults [Correction].","authors":"","doi":"10.18773/austprescr.2022.055","DOIUrl":"https://doi.org/10.18773/austprescr.2022.055","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.18773/austprescr.2021.038.].</p>","PeriodicalId":55588,"journal":{"name":"Australian Prescriber","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/53/90/austprescr-45-183a.PMC9584793.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40688211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Australian PrescriberPub Date : 2022-10-01Epub Date: 2022-10-04DOI: 10.18773/austprescr.2022.054
Jimmy Zhu, Lyn March
{"title":"Treating osteoporosis: risks and management.","authors":"Jimmy Zhu, Lyn March","doi":"10.18773/austprescr.2022.054","DOIUrl":"https://doi.org/10.18773/austprescr.2022.054","url":null,"abstract":"<p><p>Osteoporosis, osteopenia and minimal trauma fractures are becoming increasingly common in the ageing population. Fractures cause increases in morbidity and mortality and have a significant financial impact on the healthcare system and society Addressing risk factors for osteoporosis early may prevent or delay the onset of fractures and use of drugs. Calcium and vitamin D supplementation may benefit people with a high risk of deficiency (e.g. institutionalised older people) but may not be required in people without risk factors. Impact and resistance exercises and physical activity can increase bone density and prevent falls Antiresorptive drugs such as bisphosphonates and denosumab remain first-line treatment options for osteoporosis. The ongoing need for bisphosphonates should be assessed after five years and treatment may then be interrupted in some patients. Progressive bone loss will recur slowly. Denosumab therapy should not be interrupted without switching to another therapy, as post-treatment bone loss can progress rapidly. All patients will need ongoing monitoring and most will require some long-term therapy once started Raloxifene may be considered in women who do not tolerate first-line antiresorptive drugs. Romosozumab is a new anabolic treatment for osteoporosis and, together with teriparatide, is subsidised as second-line therapy for individuals with severe disease and multiple fractures. Specialist referral should be considered for patients who sustain fractures while undergoing osteoporosis therapy.</p>","PeriodicalId":55588,"journal":{"name":"Australian Prescriber","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/bf/74/austprescr-45-150.PMC9584792.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40688213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Australian PrescriberPub Date : 2022-10-01Epub Date: 2022-10-04DOI: 10.18773/austprescr.2022.051
Michael Lowy, Vijayasarathi Ramanathan
{"title":"Erectile dysfunction: causes, assessment and management options.","authors":"Michael Lowy, Vijayasarathi Ramanathan","doi":"10.18773/austprescr.2022.051","DOIUrl":"https://doi.org/10.18773/austprescr.2022.051","url":null,"abstract":"<p><p>Erectile dysfunction is one of the most common male sexual dysfunctions. The diagnosis can usually be made by a detailed history and examination. Men with erectile dysfunction benefit from multimodal management strategies. These include lifestyle modification, medical treatment and psychosexual counselling and therapy. An oral phosphodiesterase-5 inhibitor is often prescribed for erectile dysfunction. Providing simple and clear instructions is critical to realise the full benefits of these drugs. Those with severe vascular disease or a history of pelvic surgery may not respond to phosphodiesterase-5 inhibitors. Anxiety or unrealistic expectations can also result in a poor response.</p>","PeriodicalId":55588,"journal":{"name":"Australian Prescriber","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0d/48/austprescr-45-159.PMC9584785.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40688209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bariatric surgery and medicines: from first principles to practice.","authors":"Teresa Girolamo, Rosemary Allin","doi":"10.18773/austprescr.2022.053","DOIUrl":"https://doi.org/10.18773/austprescr.2022.053","url":null,"abstract":"<p><p>Obesity is a major public health issue with significant health and financial costs. Almost one in three Australian adults are living with obesity Bariatric surgery can have a role in the management of obesity. There is evidence for its effectiveness in preventing or reversing chronic health conditions The type of bariatric surgery can significantly impact the absorption, distribution, metabolism or elimination of orally administered drugs. Some changes can be predicted from pharmacokinetic and physiological effects, but management should be individualised The effect of weight loss itself after bariatric surgery may require drug doses to be altered A review of the patient's medicines and ongoing follow-up are important before and after surgery to ensure optimal outcomes.</p>","PeriodicalId":55588,"journal":{"name":"Australian Prescriber","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3b/76/austprescr-45-162.PMC9584784.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10429472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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