{"title":"[The EEG of patients with acute manic psychoses before, during and after treatment with high doses of d-propranolol and dl-propranolol (author's transl)].","authors":"K Coulin, O Simon, H M Emrich, D von Zerssen","doi":"10.1007/BF00345588","DOIUrl":"https://doi.org/10.1007/BF00345588","url":null,"abstract":"<p><p>Six manic patients, drug-free for at least 10 days, were treated with high doses (up to 3,000 mg/day, corresponding serum levels up to 1,600 ng/ml) of d-propranolol or dl-propranolol in a double-blind, placebo-controlled study. The EEG's of these patients were studied over a maximum period of 21 days. All 82 EEG's were normal, they showed neither epileptic patterns nor any other signs for hypersynchronisation, as a possible side-effect of propranolol, nor other abnormalities, due to the manic condition. Analysis by fast-fourier-transformation produced no difference between the effect of d-propranolol or dl-propranolol on EEG compared intra- and inter-hemispherically by power-spectra, cross-spectra, phase-differences and coherences. At high serum levels (more than 1,000 ng/ml) there was a corresponding increase of power and a drop in frequency of the alpha-activity, maximally--1.1 c/s, which probably depended on the serum level. This result is in agreement with the hypothesis of a direct antimanic effect of the drug and comparable to the clinical effect of lithium, which produces similar changes in EEG. A comparison of the propranolol-induced EEG changes with EEG changes usually induced by sedative drugs, contradicts the hypothesis that the antimatic properties of propranolol are caused by unspecific sedation.</p>","PeriodicalId":55482,"journal":{"name":"Archiv Fur Psychiatrie Und Nervenkrankheiten","volume":"231 4","pages":"323-31"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00345588","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18099122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Schizophrenia's classical subtypes. A family heredity study.","authors":"C Scharfetter","doi":"10.1007/BF00342723","DOIUrl":"https://doi.org/10.1007/BF00342723","url":null,"abstract":"<p><p>A genetic family study of the classical schizophrenic subgroups (33 hebephrenics, 38 catatonics, 69 paranoid schizophrenics) demonstrated a tendency towards differences in the global morbidity risk of schizophrenia (greatest in the relatives of catatonics) and a tendency towards a predominance of homotypical secondary cases. However, as these results are statistically not significant, they cannot be used as arguments in discussing the genetic separation of schizophrenic subtypes.</p>","PeriodicalId":55482,"journal":{"name":"Archiv Fur Psychiatrie Und Nervenkrankheiten","volume":"231 5","pages":"443-7"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00342723","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18140980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Brachial neuropathy--a vascular cause? Two case reports.","authors":"B Hindfelt","doi":"10.1007/BF00343698","DOIUrl":"https://doi.org/10.1007/BF00343698","url":null,"abstract":"<p><p>The pathogenesis of brachial neuropathy remains unknown though an infectious or allergic disorder has been postulated. The causes are probably diverse. Two patients are presented suffering from brachial neuropathy of presumed vascular origin.</p>","PeriodicalId":55482,"journal":{"name":"Archiv Fur Psychiatrie Und Nervenkrankheiten","volume":"232 2","pages":"179-81"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00343698","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18172253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sir Karl Popper.","authors":"J Eccles","doi":"10.1007/BF00343359","DOIUrl":"https://doi.org/10.1007/BF00343359","url":null,"abstract":"","PeriodicalId":55482,"journal":{"name":"Archiv Fur Psychiatrie Und Nervenkrankheiten","volume":"232 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00343359","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17809633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Auditory evoked potentials to verbal stimuli in health, aphasic, and right hemisphere damaged subjects. Pathway effects and parallels to language processing and attention.","authors":"A Rothenberger, J Szirtes, R Jürgens","doi":"10.1007/BF00343837","DOIUrl":"https://doi.org/10.1007/BF00343837","url":null,"abstract":"<p><p>Acoustic evoked potentials to meaningful words were recorded in healthy, aphasic, and right hemisphere-damaged subjects under four conditions: monaural left and right, binaural, and dichotic stimulation. Four major findings emerged. First, healthy and brain-damaged subjects differed in amplitude and latency values of the N1 and P2 components. In healthy subjects N1 was greater and P2 smaller than in aphasics. Both components peaked earlier inpatients than in normals. Second, evoked potentials of healthy subjects showed a late sustained component which was decreased in aphasics. Third, the latencies of P1 and N1 as well as the amplitude of N1 showed a \"pathway effect\", i.e. shorter latency and greater amplitude to contralateral stimulation. Fourth, under the dichotic condition, P1 and N1 peaked earlier over the left hemisphere. The N1 amplitude behaved differently in the three groups depending upon stimulating conditions. It is suggested that these differences reflect linguistic coding and related attentional processes in patients and normals.</p>","PeriodicalId":55482,"journal":{"name":"Archiv Fur Psychiatrie Und Nervenkrankheiten","volume":"231 2","pages":"155-70"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00343837","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18112509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The recovery after delirium tremens investigated by psychological testing (author's transl)].","authors":"P Steck, E Holzbach, A Rausche","doi":"10.1007/BF00345593","DOIUrl":"https://doi.org/10.1007/BF00345593","url":null,"abstract":"<p><p>Following admission with delirium tremens to the University of Würzburg mental hospital, 83 alcoholics were investigated on their fourth day and their fourth week after finishing therapy for the delirium. They were investigated by psychological tests for achievement, resulting in 13 variables, and by a personality inventory. Of the 13 variables of achievement 4 increased significantly from the first investigation to the second, one was for verbal thinking, another was for numerical thinking, and finally they were two tests for attention. The personality inventory scores showed 3 significant changes indicating a clinical improvement: \"nervousness\", \"depression\", and \"inhibition\". For 7 variables of achievement the patients scored significantly below the normal average score, these were the 2 numerical tests, all variables of the memory tests, the verbal test, and 1 variable of the attention test. Except for the last test the average scores remained significantly below the normal average at the second investigation. The results of 5 scales of the personality inventory were significantly different to the norm in the first investigation; there were no differences on the second date.</p>","PeriodicalId":55482,"journal":{"name":"Archiv Fur Psychiatrie Und Nervenkrankheiten","volume":"231 4","pages":"375-90"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00345593","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18130826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R Cohen, A Glöckner-Rist, M Lutz, T Maier, E Meier
{"title":"Cognitive impairments of aphasics in picture sorting and matching tasks.","authors":"R Cohen, A Glöckner-Rist, M Lutz, T Maier, E Meier","doi":"10.1007/BF02141783","DOIUrl":"https://doi.org/10.1007/BF02141783","url":null,"abstract":"<p><p>On the basis of earlier experiments showing a differential deficit of aphasics in picture sorting and matching tasks, two experiments were conducted to test the conjecture of a specific deficit of aphasics in the analytical appraisal of individual features. Broca's and Wernicke's aphasics--according to clinical diagnoses and the Aachener Aphasie Test--were compared with patients having right-hemisphere lesions or left-hemisphere lesions without aphasia. Both groups of aphasics differed from the control groups in the sorting task, irrespective of the sorting criterion, but the differences were small. The picture matching task did not discriminate between groups. Obviously, the basic assumption has to be modified with respect to specific conditions of task requirements. The experimental literature is reviewed.</p>","PeriodicalId":55482,"journal":{"name":"Archiv Fur Psychiatrie Und Nervenkrankheiten","volume":"232 3","pages":"223-34"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02141783","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18172256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Neurophysiologic aspects of psychoorganic deficiency problems of depressive disorders of the involutional age].","authors":"J Böning","doi":"10.1007/BF02141784","DOIUrl":"https://doi.org/10.1007/BF02141784","url":null,"abstract":"<p><p>From a multidimensional viewpoint 40 depressive patients of involutional age (mean age 55 years) were evaluated in terms of an operationally defined deficiency syndrome, i.e. vital reduction per organic brain coloration to establish a neurobiologic matrix of correlation between the level of clinical psychopathology and neurophysiology. A subtle diagnosis by means of evoked potentials (SEP and VEP) measuring the neuronal infrastructure allows for a global evaluation of sensory-specific \"cortical-subcortical functional integrity\", otherwise missed in terms of the conventional EEG. In both vitally reduced patients and in probands who were diagnosed as having an organic brain syndrome because of clinical psychopathologic phenomenology, impaired bioelectric signal processing, increased neuropsychological deficits, risk factors and enlargement of the third ventricle were measured together with a chronic course of the nosologically classified disease. Compared with depressive patients who may have any deficiency factor, and healthy elderly probands (mean age 86 years), a deficiency syndrome is suggested as being defined as a polysystemic aging process which is dynamically induced by endogenous and exogenous factors, thus, being time dependent. Although there are correlative results between the disciplines, an abnormal (neuronal) functional diagram should only be used in a pathoplastic sense as an indicative and associative reaction of the CNS to premature aging processes at various levels.</p>","PeriodicalId":55482,"journal":{"name":"Archiv Fur Psychiatrie Und Nervenkrankheiten","volume":"232 3","pages":"235-50"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02141784","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18172257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Temporal slow activity of the EEG in old age.","authors":"A Kazis, A Karlovasitou, D Xafenias","doi":"10.1007/BF00343998","DOIUrl":"https://doi.org/10.1007/BF00343998","url":null,"abstract":"","PeriodicalId":55482,"journal":{"name":"Archiv Fur Psychiatrie Und Nervenkrankheiten","volume":"231 6","pages":"547-54"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00343998","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18153826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Peripheral motor neuropathy caused by excessive intake of dapsone (Avlosulfon).","authors":"I Rosén, R Sörnäs","doi":"10.1007/BF00343366","DOIUrl":"https://doi.org/10.1007/BF00343366","url":null,"abstract":"<p><p>A case of selective peripheral motor polyneuropathy caused by excessive intake of dapsone is described. The condition was characterized by a peripheral muscle weakness in all limbs, normal sensitivity and present, although weak, muscle reflexes. Neurophysiologically, low amplitude muscle responses, prolonged distal latencies and reduced motor conduction velocities were found together with electromyographic signs of denervation. Sensory neurography was normal. The patient showed a complete clinical recovery and a marked neurophysiological restitution after termination of the excessive drug intake. The patient was found to acetylate dapsone at a slow rate. The case is compared with those previously reported in the literature.</p>","PeriodicalId":55482,"journal":{"name":"Archiv Fur Psychiatrie Und Nervenkrankheiten","volume":"232 1","pages":"63-9"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00343366","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17355130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}