Biology Bulletin最新文献_第10页

Drosophila Tak1 Mediates the Condensation and Deubiquitinase Activity of Otu in a Kinase-Independent Manner 果蝇 Tak1 以一种与激酶无关的方式介导奥图的缩聚和去泛素酶活性

IF 0.5 4区生物学

Biology Bulletin Pub Date : 2024-03-26 DOI: 10.1134/s1062359023605013

Chuchu Zhang, Xueli Shao, Zhuolan Xia, Yihua Xiao, Baoyi Hu, Yulong Yang, Xiangyun Li, Zhen Zhang, Abdul Qadeer, Yangyang Zhu

{"title":"Drosophila Tak1 Mediates the Condensation and Deubiquitinase Activity of Otu in a Kinase-Independent Manner","authors":"Chuchu Zhang, Xueli Shao, Zhuolan Xia, Yihua Xiao, Baoyi Hu, Yulong Yang, Xiangyun Li, Zhen Zhang, Abdul Qadeer, Yangyang Zhu","doi":"10.1134/s1062359023605013","DOIUrl":"https://doi.org/10.1134/s1062359023605013","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Abstract</h3>In the intricate molecular world, post-translational modifications play pivotal roles in modulating protein activity and function. The Drosophila melanogaster genome encodes an array of enzymes to mediate these processes. Here, we elucidate a previously unrecognized connection between the Drosophila transforming growth factor-β-activated kinase 1 (dTak1) and the deubiquitinase Ovarian tumor (Otu). We demonstrate that dTak1 mediates both the phase-separated condensation and the deubiquitinase enzymatical activity of Otu in a manner independent of its kinase function. Using a combination of biochemical assays and in vivo genetic interactions, our findings highlight the significance of dTak1 in orchestrating the assembly of Otu condensates, and consequently, in the regulation of Otu’s biological functions. Our studies underscore the multifaceted nature of protein-protein interactions and open up avenues for exploring non-traditional roles of kinases in cellular processes.","PeriodicalId":55366,"journal":{"name":"Biology Bulletin","volume":"49 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140313640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New Lichenicolous Phyllopsora (Ramalinaceae) Species on Phaeophyscia from India 印度 Phaeophyscia 上的地衣菌 Phyllopsora（Ramalinaceae）新种

IF 0.5 4区生物学

Biology Bulletin Pub Date : 2024-03-26 DOI: 10.1134/s1062359023605657

Pooja Maurya, Gaurav K. Mishra, Dalip K. Upreti

引用次数: 0

New Records of Lichenicolous Fungi Inhabiting Cladonia from India 印度地衣真菌的新记录

IF 0.5 4区生物学

Biology Bulletin Pub Date : 2024-03-26 DOI: 10.1134/s1062359023606055

引用次数: 0

Recent Species’ Range Expansion in the Himalayan Highlands: New Distribution Records of Naturalized Alien Plants from Ladakh, India 喜马拉雅高原最近的物种分布范围扩张：印度拉达克归化外来植物的新分布记录

IF 0.5 4区生物学

Biology Bulletin Pub Date : 2024-03-26 DOI: 10.1134/s1062359023606079

Shabir A. Zargar, Anzar Ahmad Khuroo, Zafar A. Reshi, Aijaz Hassan Ganie

引用次数: 0

Regulation of Ovary Function in Aged Mice by Reactive Oygen Species through the PI3K/Akt/mTOR Pathway 活性氧通过 PI3K/Akt/mTOR 途径调控老年小鼠的卵巢功能

IF 0.5 4区生物学

Biology Bulletin Pub Date : 2024-03-26 DOI: 10.1134/s1062359023604640

Li Huang, Duanheng Wang, Ailing Zhou, Mingming Qian, Chong Zhou

{"title":"Regulation of Ovary Function in Aged Mice by Reactive Oygen Species through the PI3K/Akt/mTOR Pathway","authors":"Li Huang, Duanheng Wang, Ailing Zhou, Mingming Qian, Chong Zhou","doi":"10.1134/s1062359023604640","DOIUrl":"https://doi.org/10.1134/s1062359023604640","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Abstract</h3>In this study, we aimed to explore the effect and underlying mechanism of aging in female ovarian function in mice. The mice at the age of 10 months and 7 weeks were used as the aged model and the young control. The estrus cycle and serum peripheral blood and the number of follicles, oocytes and litter size were also calculated for analysis of ovarian function. Ovarian cells were collected for reactive oxygen species (ROS) and Annexin V staining. Antioxidant and apoptotic proteins BAX and Caspase-3 and phosphoinositol-3-kinase (PI3K)/protein kinase B (Akt)/mammalian target of rapamycin (mTOR) pathway in ovaries were also detected. The results showed that compared to the young control, the aged mice exhibited ovarian dysfunction with disrupted estrus cycle and hormone production, accompanied by decreases in the numbers of follicles, oocytes and litter size. The oxidative damage in aged ovarian tissues was induced with increased Malondialdehyde content and reduced activities of Catalase and Superoxide Dismutase enzymes, as well as high level of ROS accumulation and apoptosis in ovarian cells. Furthermore, the expression levels of BAX, Caspase-3 and PI3K, Akt, mTOR and their phosphorylated forms were obviously regulated in the aged ovaries. Thus, these results above suggest oxidative damage with high level of ROS is obviously induced in ovarian tissues of aged mice, and this accumulation mediates apoptosis of ovarian cells, involving with improved expression of apoptotic protein BAX and Caspase-3, ultimately leads to ovarian dysfunction through the PI3K/Akt/mTOR pathway.","PeriodicalId":55366,"journal":{"name":"Biology Bulletin","volume":"187 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140313653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Methyl Jasmonate’s Role in Alleviating Salt Stress-Induced Challenges in Narcissus Growth 茉莉酸甲酯在缓解盐胁迫对水仙生长造成的挑战中的作用

IF 0.5 4区生物学

Biology Bulletin Pub Date : 2024-03-26 DOI: 10.1134/s1062359023605694

Raha Tabrizi Dooz, Davood Naderi, Sepideh Kalatehjari, Hossein Ali Asadi Gharneh, Marzieh Ghanbari Jahromi

{"title":"Methyl Jasmonate’s Role in Alleviating Salt Stress-Induced Challenges in Narcissus Growth","authors":"Raha Tabrizi Dooz, Davood Naderi, Sepideh Kalatehjari, Hossein Ali Asadi Gharneh, Marzieh Ghanbari Jahromi","doi":"10.1134/s1062359023605694","DOIUrl":"https://doi.org/10.1134/s1062359023605694","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Abstract</h3>High soil salinity, a result of salt stress, poses a significant obstacle to crop cultivation, particularly for ornamental plants like narcissus. Plant growth regulators, such as methyl jasmonate (MeJA), have the potential to mitigate the impact of stressful conditions. This study involved different MeJA concentrations (0, 50, 100, and 200 µM) and varying levels of salt stress (4 and 8 dS m–1), along with a control level, in a pot experiment conducted using a complete randomized block design with three replicates at the Research Greenhouse, Islamic Azad University, Isfahan (Khorasgan) Branch. The research revealed that salt stress led to a substantial increase in leaf proline and flavonoid levels, as well as electrolyte leakage (EL), hydrogen peroxide (H2O2), malondialdehyde (MDA), catalase (CAT), and superoxide dismutase (SOD) enzymatic activities. These increases were more pronounced when MeJA was applied concurrently with a decrease in EL, H2O2, and MDA. Conversely, salt stress was observed to reduce chlorophyll and carotenoid levels, relative water content (RWC), flower fresh weight, flower longevity on the plant, and flowering duration. This underscores MeJA’s potential as a growth regulator that safeguards narcissus against salinity toxicity. The findings indicate that 100 µM MeJA activates an effective mechanism to mitigate the adverse effects of salinity.","PeriodicalId":55366,"journal":{"name":"Biology Bulletin","volume":"80 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140313646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New Data on Aquatic Flora of Dagestan 关于达吉斯坦水生植物群的新数据

IF 0.5 4区生物学

Biology Bulletin Pub Date : 2024-03-26 DOI: 10.1134/s1062359023605554

引用次数: 0

Macro- and Microstructural Features from the Feathers of Four Columbidae Species 四种哥伦布科鸟类羽毛的宏观和微观结构特征

IF 0.5 4区生物学

Biology Bulletin Pub Date : 2024-03-26 DOI: 10.1134/s106235902360650x

Swapna Devi Ray, Olga Silaeva, Goldin Quadros, Prateek Dey, Padmanabhan Pramod, Ram Pratap Singh

{"title":"Macro- and Microstructural Features from the Feathers of Four Columbidae Species","authors":"Swapna Devi Ray, Olga Silaeva, Goldin Quadros, Prateek Dey, Padmanabhan Pramod, Ram Pratap Singh","doi":"10.1134/s106235902360650x","DOIUrl":"https://doi.org/10.1134/s106235902360650x","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">\u0000Abstract—</h3>Plumology is being used in a variety of avian research fields such as from ecology and evolution to prey-predator relationship. However, very few systematic studies have been conducted in India using plumology. The paper compares macro- and micro-structural feathers’ features from four species of family Columbidae viz. the Spotted dove (Spilopelia chinensis), Grey-fronted green pigeon (Treron affinis), Eurasian collared dove (Streptopelia decaocto) and Common pigeon (Columba livia) from different Indian localities. A morphometric analysis of the downy and contour feathers’ structures of the listed species was carried out. Since the feathers were taken from significantly damaged carcasses, it was necessary to determine the pterylae of the flying feathers to which the latter belong. Morphometric features of feathers viz. calamus, rachis, vane and mounted barb length were measured. An atypical for Columbidae feature presence of villi has been observed but only for T. affinis species. The presence of typical pigmented quadrilobed nodes was noted in all Columbidae species. Pigmented and non-pigmented plain pronged nodes and plain swollen nodes were observed. The presence of three different nodes on barbules and nodes’ pigmentation may be considered as key taxonomic characteristics for studied Columbidae species. The feather comparison method made it possible to identify pterylae of studied feathers.","PeriodicalId":55366,"journal":{"name":"Biology Bulletin","volume":"44 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140313728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chloroplast Genome Sequence and Phylogenetic Analysis of Medicinal Plant Pinellia ternata 药用植物半夏的叶绿体基因组序列和系统发育分析

IF 0.5 4区生物学

Biology Bulletin Pub Date : 2024-02-09 DOI: 10.1134/s106235902360472x

{"title":"Chloroplast Genome Sequence and Phylogenetic Analysis of Medicinal Plant Pinellia ternata","authors":"","doi":"10.1134/s106235902360472x","DOIUrl":"https://doi.org/10.1134/s106235902360472x","url":null,"abstract":" <h3>Abstract</h3> Pinellia ternata, as one of the traditional Chinese medicines, has a significant effect on eliminating dampness, stopping vomiting and calm the adverse-rising energy. There are few researches on the structural characteristics of the chloroplast genome of P. ternata, which is not conducive to its further development. Therefore, we studied the chloroplast genome sequence of P. ternata to provide scientific basis for the development of P. ternata and phylogenetic analysis of Araceae. We fabricate the complete chloroplast genomes of P. ternata using Illumina (HiSeq X) sequencing technology. The chloroplast genome of P. ternata has the same gene order and organization as the chloroplast genomes of other Araceae. The P. ternata complete chloroplast genomes is 163 711 bp in length, exhibits a conserved quadripartite structure with a large single-copy (LSC; 92 562 bp) region, and a small single-copy (SSC; 23 805 bp) region interspersed between inverted repeat (IRa/IRb; 25 474 bp) region. A total of 128 unique genes were annotated, including 83 protein-coding genes, 37 tRNA, and 8 rRNA. 143 SSR loci were retrieved from the genome, with mononucleotide is the most frequently distributed type, and hexanucleotides are the rarest type. In addition, 50 long repeats sequences were found in tandem repeats. We made phylogenetic trees from 18 Araceae species and 2 Caldesia species using ML method. This study provides a valuable reference for the systematic location and chloroplast genome information of Pinellia ternata in Araceae. ","PeriodicalId":55366,"journal":{"name":"Biology Bulletin","volume":"15 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139771390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Differential Expression of MicroRNAs in the Kidneys of Rats Following Sustained Swimming Exercise 持续游泳运动后大鼠肾脏中 MicroRNA 的差异表达

IF 0.5 4区生物学

Biology Bulletin Pub Date : 2024-02-09 DOI: 10.1134/s1062359023603063

Junling Li, Fengyuan Sun, Rongguang Hu, Xianwei Zhou, Anmin Zhang

{"title":"Differential Expression of MicroRNAs in the Kidneys of Rats Following Sustained Swimming Exercise","authors":"Junling Li, Fengyuan Sun, Rongguang Hu, Xianwei Zhou, Anmin Zhang","doi":"10.1134/s1062359023603063","DOIUrl":"https://doi.org/10.1134/s1062359023603063","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Abstract</h3>Swimming exercise is reported to have protective effects on kidney function. Previous studies have indicated that microRNAs (miRNAs) are important for normal development, physiology, and pathophysiology of the kidney. Previous publications reported that swimming could modify miRNA expression profiles in the heart and brain. We studied the differential expression of miRNA in the kidneys of rats following sustained swimming exercise twice a day for 6 consecutive weeks. Small RNA libraries were made from the kidneys of sedentary control (SC) and sustained swimming exercised (SE) animals to identify the expression of miRNAs using high-throughput (deep) sequencing technology. We identified 521 and 516 known miRNAs and revealed 328 and 312 novel miRNA candidates with a total of 849 and 828 miRNAs in the kidneys of rats from the SC and SE libraries, respectively. Seventeen miRNAs were differentially expressed, of which 10 miRNAs were increased and 7 miRNAs were decreased in response to swimming exercise. The results showed that sustained swimming exercise could modulate renal miRNAs in rats. These differentially modified miRNA-s were investigated employing Gene Ontology (GO) terminologies and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways. The results implied that these swimming-responsive miRNAs may interact with many types of target genes to regulate renal functions. Analysis of KEGG pathways found that the significantly enriched target genes of the modified miRNAs were involved in the thyroid signaling (ko04919) and Hippo signaling pathways (ko04390). Our study data suggest that sustained swimming exercise could induce deferential expression of renal miRNAs, which might modulate an adaptive response of the kidney.","PeriodicalId":55366,"journal":{"name":"Biology Bulletin","volume":"15 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139771401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0