Current Opinion in Obstetrics & Gynecology最新文献_第10页

GnRH agonist trigger in poor prognosis patients undergoing a multicycle approach through DuoStim or consecutive stimulations: a SWOT analysis. 通过 DuoStim 或连续刺激对预后不良患者进行多周期治疗的 GnRH 激动剂触发：SWOT 分析。

IF 2.1 4区医学

Current Opinion in Obstetrics & Gynecology Pub Date : 2024-06-01 Epub Date: 2024-03-26 DOI: 10.1097/GCO.0000000000000947

Alberto Vaiarelli, Alessandro Ruffa, María Cerrillo, Juan Antonio García-Velasco

{"title":"GnRH agonist trigger in poor prognosis patients undergoing a multicycle approach through DuoStim or consecutive stimulations: a SWOT analysis.","authors":"Alberto Vaiarelli, Alessandro Ruffa, María Cerrillo, Juan Antonio García-Velasco","doi":"10.1097/GCO.0000000000000947","DOIUrl":"10.1097/GCO.0000000000000947","url":null,"abstract":"Purpose of review: Identify the most recent and significant evidence regarding the ovulation trigger within the framework of a multicycle approach through DuoStim, providing valuable insights for improving treatment strategies in patients with a poor prognosis.Recent findings: The trigger method plays a pivotal role in optimizing in-vitro fertilization (IVF) stimulation, influencing oocyte retrieval and maturation rates, as well as follicle recruitment in consecutive ovarian stimulations such as double stimulation. Decision-making involves multiple factors and, while guidelines exist for conventional stimulation, specific recommendations for the multicycle approach are not well established.Summary: The different methods for inducing oocyte maturation underscore the need for personalization of IVF protocols. The GnRH agonist trigger induces rapid luteolysis and establishes favorable hormonal conditions that do not adversely affect the recruitment of consecutive follicular waves in the context of DuoStim. It serves as a valid alternative to hCG in freeze-all cycles. This strategy might enhance the safety and flexibility of ovarian stimulations with no impact on oocyte competence and IVF efficacy.","PeriodicalId":55194,"journal":{"name":"Current Opinion in Obstetrics & Gynecology","volume":"36 3","pages":"124-133"},"PeriodicalIF":2.1,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140868981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Abstinence for sperm sample collection and ART outcome: an unsubstantiated myth. 禁欲采集精子样本与抗逆转录病毒疗法的结果：一个未经证实的神话。

IF 2.2 4区医学

Current Opinion in Obstetrics & Gynecology Pub Date : 2024-06-01 Epub Date: 2024-03-26 DOI: 10.1097/GCO.0000000000000946

Peter N Schlegel

引用次数: 0

Ideal frozen embryo transfer regime. 理想的冷冻胚胎移植制度

IF 2.1 4区医学

Current Opinion in Obstetrics & Gynecology Pub Date : 2024-06-01 Epub Date: 2024-01-31 DOI: 10.1097/GCO.0000000000000943

Juan Castillo, Shahar Kol

{"title":"Ideal frozen embryo transfer regime.","authors":"Juan Castillo, Shahar Kol","doi":"10.1097/GCO.0000000000000943","DOIUrl":"10.1097/GCO.0000000000000943","url":null,"abstract":"Purpose of review: This review aims to compare evidence on four criteria (embryo implantation, obstetric outcomes, patient convenience, and IVF-unit efficiency) by analyzing published research on different endometrial preparation methods for frozen embryo transfer (FET).Recent findings: While the artificial-FET cycle provides advantages in scheduling and implantation, it falls short in ensuring optimal obstetric outcomes. In contrast, natural-FET ensures embryo implantation conditions if ovulation is correctly identified. Supplementing with exogenous progesterone shields against low corpus luteum progesterone secretion, crucial for positive obstetric outcomes. In mNC-FET, ovulation is hCG-triggered, closely resembling natural cycles and reducing monitoring visits for enhanced patient convenience.Letrozole is a recommended option for anovulatory patients, preserving endometrial thickness. It is cost-effective, less likely to induce multifollicular development than gonadotropins, and better tolerated.In a novel approach, the natural-proliferative-phase-FET initiates progesterone in an unmediated ovulatory cycle at 7 mm endometrial thickness, combining the benefits of a natural proliferative endometrium with the convenience of scheduled artificial cycles.Summary: The artificial cycle offers scheduling advantages, but may compromise obstetric outcomes. Natural FET relies on accurate ovulation timing for successful implantation. mNC-FET simplifies the process using hCG induction, minimizing clinic visits for improved convenience. Letrozole is highlighted as a cost-effective and well tolerated option in anovulatory patients. A recent innovative approach combines elements of natural and artificial cycles, showing promise for FET procedures.","PeriodicalId":55194,"journal":{"name":"Current Opinion in Obstetrics & Gynecology","volume":" ","pages":"148-154"},"PeriodicalIF":2.1,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139652240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Not all platelet-rich plasma are created equal. 并非所有的富血小板血浆都是一样的。

IF 2.1 4区医学

Current Opinion in Obstetrics & Gynecology Pub Date : 2024-06-01 Epub Date: 2024-02-05 DOI: 10.1097/GCO.0000000000000944

Manuel Muñoz Cantero

{"title":"Not all platelet-rich plasma are created equal.","authors":"Manuel Muñoz Cantero","doi":"10.1097/GCO.0000000000000944","DOIUrl":"10.1097/GCO.0000000000000944","url":null,"abstract":"Purpose of review: This review aims to elucidate potential variations in clinical outcomes resulting from the use of different types of platelet-rich plasma (PRPs) in reproductive medicine. It seeks to explore the reasons behind the diverse results reported in various studies and assess the general features distinguishing different PRP formulations.Recent findings: PRPs have found applications across diverse medical fields, generating controversy due to the variability in outcomes. The field of reproductive medicine, despite its limited published studies, is encountering a similar challenge as it integrates these treatments.Summary: The multitude of PRP product brands in the market, coupled with 'home-made' PRPs, poses a significant barrier to establishing a common protocol for the preparation of standardized PRP products. This impediment hinders widespread adoption by clinicians, particularly in endometrial or ovarian treatments. Drawing from evidence in other medical disciplines, this review endeavors to compile essential characteristics that PRPs must possess, aiming to mitigate the impact of variables affecting results in forthcoming studies.","PeriodicalId":55194,"journal":{"name":"Current Opinion in Obstetrics & Gynecology","volume":" ","pages":"118-123"},"PeriodicalIF":2.1,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139704096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Walking on thin endometrium. 在薄薄的子宫内膜上行走

IF 2.2 4区医学

Current Opinion in Obstetrics & Gynecology Pub Date : 2024-06-01 Epub Date: 2024-03-20 DOI: 10.1097/GCO.0000000000000948

Baris Ata, Begum Mathyk, Savci Telek, Erkan Kalafat

引用次数: 0

An update on the current indications for in vitro maturation. 体外成熟的最新适应症。

IF 2.2 4区医学

Current Opinion in Obstetrics & Gynecology Pub Date : 2024-06-01 Epub Date: 2024-01-31 DOI: 10.1097/GCO.0000000000000942

Vu N-A Ho, Tuong M Ho, Lan N Vuong, Juan García-Velasco

{"title":"An update on the current indications for in vitro maturation.","authors":"Vu N-A Ho, Tuong M Ho, Lan N Vuong, Juan García-Velasco","doi":"10.1097/GCO.0000000000000942","DOIUrl":"10.1097/GCO.0000000000000942","url":null,"abstract":"Purpose of review: In vitro maturation has become a significant component of modern assisted reproductive techniques. Published data have been supported for the safety and effectiveness of in vitro maturation treatment. In recent years, potential indications for in vitro maturation (IVM) have been a topic of interest and investigation.Recent findings: Significant improvements in technique enhancement and data publication for evaluating the efficacy of IVM have been achieved. Recent studies have shown that IVM could offer several advantages over in vitro fertilization. Currently, there are growing indications for IVM beyond the commonly mentioned indication of infertile women with polycystic ovary syndrome. Additionally, some potential candidates might have significant advantages for IVM, such as women diagnosed with gonadotropin resistance ovary syndrome or those seeking fertility preservation. With a better understanding of IVM, from basic science to clinical practice, it can be applied safely, effectively, and affordably to a broader range of patients, making it a more accessible and patient-friendly option.Summary: Despite the possibly acknowledged limitations, the potential of in vitro maturation cannot be denied. As this technique becomes increasingly accessible to patients and more continuous efforts are dedicated to advancing this technique, the impact of in vitro maturation is expected.","PeriodicalId":55194,"journal":{"name":"Current Opinion in Obstetrics & Gynecology","volume":" ","pages":"173-180"},"PeriodicalIF":2.2,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139652239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advancements in the application of uterine ultrasound elastography. 子宫超声弹性成像技术的应用进展。

IF 2.2 4区医学

Current Opinion in Obstetrics & Gynecology Pub Date : 2024-06-01 Epub Date: 2024-03-26 DOI: 10.1097/GCO.0000000000000949

Francesca Barrett, Stephanie Willson, Marie Werner

{"title":"Advancements in the application of uterine ultrasound elastography.","authors":"Francesca Barrett, Stephanie Willson, Marie Werner","doi":"10.1097/GCO.0000000000000949","DOIUrl":"10.1097/GCO.0000000000000949","url":null,"abstract":"Purpose of review: This article reviews recent advances in ultrasound elastography in diagnosing and evaluating the normal nongravid uterus and the infertile uterus in the gynecologic patient.Recent findings: Focusing on the most recent primary literature, studies have demonstrated new findings among a breadth of gynecologic clinical settings. Studies in the nongravid uterus have found that menopausal status, age, and menstrual phase have not been associated with changes in uterine tissue stiffness. Focusing on myometrial disease, there have been conflicting data regarding the ability to distinguish uterine fibroids from adenomyosis. One area of expanding research surrounding uterine elastography includes the infertile population, where ongoing studies attempt to provide a predictive model using shear wave elastography (SWE) in patients undergoing in-vitro fertilization.Summary: Ultrasound elastography has become an increasingly studied and utilized tool in assessing physiologic and pathologic processes in the field of gynecology. Evaluating tissue stiffness through strain and SWE can serve to improve diagnosis of various uterine and cervical lesions, as well as prognosticate outcomes after fertility treatments. This growing area of research will continue to establish the role and application of ultrasound elastography into clinical practice.","PeriodicalId":55194,"journal":{"name":"Current Opinion in Obstetrics & Gynecology","volume":"36 3","pages":"181-185"},"PeriodicalIF":2.2,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140866839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Editorial introductions. 编辑介绍。

IF 2.2 4区医学

Current Opinion in Obstetrics & Gynecology Pub Date : 2024-06-01 Epub Date: 2024-04-25 DOI: 10.1097/GCO.0000000000000954

引用次数: 0

Poor ovarian response classification systems in the clinical setting - time for an update? 临床环境中的卵巢不良反应分类系统--是时候更新了？

IF 2.2 4区医学

Current Opinion in Obstetrics & Gynecology Pub Date : 2024-06-01 Epub Date: 2024-03-27 DOI: 10.1097/GCO.0000000000000950

Andres Reig, Emre Seli

{"title":"Poor ovarian response classification systems in the clinical setting - time for an update?","authors":"Andres Reig, Emre Seli","doi":"10.1097/GCO.0000000000000950","DOIUrl":"10.1097/GCO.0000000000000950","url":null,"abstract":"Purpose of review: Poor ovarian response (POR) remains a key challenge to the success of assisted reproductive technology. Here, we offer a comprehensive review of the two main classification systems for POR, discussing their promises and pitfalls, evaluating their performance, and exploring potential avenues for improving upon these definitions of POR.Recent findings: The Bologna criteria represented the first meaningful attempt to create a universal POR definition. Subsequently, the POSEIDON classification system was published to provide a more nuanced view of POR, classifying patients into four groups based on age and ovarian reserve markers. A recent study evaluated the likelihood of achieving at least one euploid embryo for transfer and found that, indeed, these classification systems are effective predictors of this outcome.While these criteria provide an effective counseling tool, several limitations - not considering underlying conditions, selecting somewhat arbitrary cutoffs, and evaluating the number of oocytes retrieved regardless of maturity - highlight the importance of improving upon these systems to create a more useful tool to more accurately predict ovarian response for clinical and research purposes.Summary: In the era of personalized medicine, it is time to reconsider whether diagnostic criteria for a continuous metric such as ovarian response should be based on meeting all-or-nothing thresholds for specific parameters.","PeriodicalId":55194,"journal":{"name":"Current Opinion in Obstetrics & Gynecology","volume":"36 3","pages":"192-199"},"PeriodicalIF":2.2,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140872109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Editorial introductions. 编辑介绍。

IF 2.2 4区医学

Current Opinion in Obstetrics & Gynecology Pub Date : 2024-04-01 Epub Date: 2024-02-29 DOI: 10.1097/GCO.0000000000000937

引用次数: 0