Frontiers of Radiation Therapy and Oncology最新文献_第10页

The Cyberknife: practical experience with treatment planning and delivery. 射波刀:治疗计划和交付的实践经验。

Frontiers of Radiation Therapy and Oncology Pub Date : 2007-01-01 DOI: 10.1159/000106033

Vernon Smith, Cynthia F Chuang

引用次数: 1

Lung cancer: a model for implementing stereotactic body radiation therapy into practice. 肺癌:立体定向全身放射治疗的实践模式。

Frontiers of Radiation Therapy and Oncology Pub Date : 2007-01-01 DOI: 10.1159/0000106047

R. Timmerman, R. Abdulrahman, B. Kavanagh, John L. Meyer

{"title":"Lung cancer: a model for implementing stereotactic body radiation therapy into practice.","authors":"R. Timmerman, R. Abdulrahman, B. Kavanagh, John L. Meyer","doi":"10.1159/0000106047","DOIUrl":"https://doi.org/10.1159/0000106047","url":null,"abstract":"Primary and metastatic tumors to the lung have been principle targets for the noninvasive high-doseper- fraction treatment programs now officially called stereotactic body radiation therapy (SBRT). Highly focused treatment delivery to moving lung targets requires accurate assessment of tumor position throughout the respiratory cycle. Measures to account for this motion, either by tracking (chasing), gating, or inhibition (breath hold and abdominal compression) must be employed in order to avoid large margins of error that would expose uninvolved normal tissues. The treatments use image guidance and related treatment delivery technology for the purpose of escalating the radiation dose to the tumor itself with as little radiation dose to the surrounding normal tissues as possible. Clinical trials have demonstrated superior local control with SBRT as compared with conventionally fractionated radiotherapy. While late toxicity requires further careful assessment, acute and subacute toxicity are remarkably infrequent. Radiographic and local tissue effects consistent with bronchial damage and downstream collapse with fibrosis are common, especially with adequate doses capable of ablating tumor targets. As such, great care must be taken when employing SBRT near the serially functioning central chest structures including the esophagus and major airways. While mechanisms of this injury remain elusive, ongoing prospective trials offer the hope of finding the ideal application for SBRT in treating pulmonary targets.","PeriodicalId":55140,"journal":{"name":"Frontiers of Radiation Therapy and Oncology","volume":"40 1","pages":"368-85"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64391184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 26

Malignant melanoma--sentinel lymph node biopsy and surgical procedures. 恶性黑色素瘤，前哨淋巴结活检和外科手术。

Frontiers of Radiation Therapy and Oncology Pub Date : 2006-01-01 DOI: 10.1159/000090857

R Kaufmann

引用次数: 3

Malignant melanoma: PET/CT as a staging procedure. 恶性黑色素瘤:PET/CT作为分期程序。

Frontiers of Radiation Therapy and Oncology Pub Date : 2006-01-01 DOI: 10.1159/000090860

Stefan P Müller

引用次数: 7

Kaposi's sarcoma--radiotherapeutic aspects. 卡波西氏肉瘤——放射治疗方面。

Frontiers of Radiation Therapy and Oncology Pub Date : 2006-01-01 DOI: 10.1159/000090803

M Niewald, C Rübe

引用次数: 1

Skin and other reactions to radiotherapy--clinical presentation and radiobiology of skin reactions. 放射治疗的皮肤和其他反应——皮肤反应的临床表现和放射生物学。

Frontiers of Radiation Therapy and Oncology Pub Date : 2006-01-01 DOI: 10.1159/000090854

Wolfgang Dörr

{"title":"Skin and other reactions to radiotherapy--clinical presentation and radiobiology of skin reactions.","authors":"Wolfgang Dörr","doi":"10.1159/000090854","DOIUrl":"https://doi.org/10.1159/000090854","url":null,"abstract":"The skin represented the dose-limiting organ in radiotherapy over long periods of time. In the first third of the 20th century, radiotherapy was associated with deposition of significant radiation doses in the superficial compartments of the skin. Therefore, all major radiobiological principles, such as effects of fractionation on radiation sensitivity or volume/area effects, were initially based on observations in epidermal radiation reactions. The development of radiation sources producing mega-voltage X-rays resulted in translocation of dose maxima into the subcutaneous soft tissue. With this, and with the introduction of multiple-field irradiation techniques, severe radiation effects in the skin were almost completely prevented. However, skin reactions are still relevant to critical skin areas, such as intertriginous regions. Also, the treatment of skin tumours, which requires high skin doses, is associated with substantial skin effects. Combinations of radiotherapy, e.g. with chemotherapy or UV exposure, can significantly aggravate skin effects. Moreover, accidental radiation exposure is frequently associated with significant skin doses. Therefore, early and late reactions of the skin must still be considered clinically relevant.","PeriodicalId":55140,"journal":{"name":"Frontiers of Radiation Therapy and Oncology","volume":"39 ","pages":"96-101"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000090854","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25785388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 17

The role of radiotherapy in the management of malignant melanoma. 放射治疗在恶性黑色素瘤治疗中的作用。

Frontiers of Radiation Therapy and Oncology Pub Date : 2006-01-01 DOI: 10.1159/000090858

S Marnitz

引用次数: 4

Classification of primary cutaneous lymphomas. 原发性皮肤淋巴瘤的分类。

Frontiers of Radiation Therapy and Oncology Pub Date : 2006-01-01 DOI: 10.1159/000090801

Chalid Assaf, Matthias Steinhoff, Sylke Gellrich, Wolfram Sterry

引用次数: 8

Potential of radiation therapy in the multimodal management of merkel cell carcinoma. 放射治疗在默克尔细胞癌多模式治疗中的潜力。

Frontiers of Radiation Therapy and Oncology Pub Date : 2006-01-01 DOI: 10.1159/000090853

G Becker, D Bottke

引用次数: 6

Merkel cell carcinoma--clinical presentation and treatment. 默克尔细胞癌的临床表现和治疗。

Frontiers of Radiation Therapy and Oncology Pub Date : 2006-01-01 DOI: 10.1159/000090806

Ingrid Moll

引用次数: 10