InternistPub Date : 2022-03-01Epub Date: 2021-11-26DOI: 10.1007/s00108-021-01210-x
O Kherbouche, W Ehrhardt, H Schweneker, R R Plentz, L P Graf
{"title":"[Thrombus in all four heart chambers in a 67-year-old female patient with pulmonary artery embolism and open foramen ovale].","authors":"O Kherbouche, W Ehrhardt, H Schweneker, R R Plentz, L P Graf","doi":"10.1007/s00108-021-01210-x","DOIUrl":"10.1007/s00108-021-01210-x","url":null,"abstract":"<p><p>A 67-year-old woman presented to the emergency department due to acute dyspnea. Computed tomography of the chest showed a pronounced bilateral pulmonary artery embolism. Echocardiography demonstrated a large floating thrombus in the right atrium and right ventricle, which extended through a persistent foramen ovale via the left atrium into the left ventricle. A thrombectomy was later successfully performed.</p>","PeriodicalId":54924,"journal":{"name":"Internist","volume":" ","pages":"321-324"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39661183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
InternistPub Date : 2022-03-01Epub Date: 2022-01-17DOI: 10.1007/s00108-022-01264-5
Mirja Mittermaier, Christian Sina, Jutta G Richter, Matthias Raspe, Patrick Stais, Jörg Vehreschild, Sebastian Wolfrum, Christina Anthes, Martin Möckel
{"title":"[Practical use of digital health applications (DiGA) in internal medicine].","authors":"Mirja Mittermaier, Christian Sina, Jutta G Richter, Matthias Raspe, Patrick Stais, Jörg Vehreschild, Sebastian Wolfrum, Christina Anthes, Martin Möckel","doi":"10.1007/s00108-022-01264-5","DOIUrl":"10.1007/s00108-022-01264-5","url":null,"abstract":"<p><p>Since 2020 physicians can prescribe digital health applications (DiGA), also colloquially known as apps on prescription, which are reimbursed by the statutory health insurance when they are approved by the Federal Institute for Drugs and Medical Devices (BfArM) and are included in the DiGA Ordinance. Currently, there is one approved DiGA (indication obesity) for internal medicine. There are many questions on the practical use of the DiGA, ranging from the prescription, the effectiveness, the complexities and reimbursement as well as the liability risks. The DiGA are innovative new means, which maybe support internal medicine physicians in the diagnostics and treatment in the future. The benefits in this field of indications are limited by unclarified issues, especially on the prescription practice and the currently low number of DiGA available in internal medicine.</p>","PeriodicalId":54924,"journal":{"name":"Internist","volume":" ","pages":"245-254"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39826951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
InternistPub Date : 2022-03-01Epub Date: 2022-02-09DOI: 10.1007/s00108-021-01257-w
Stephan C Bischoff
{"title":"[Food sensitivities of the digestive tract-Part 2: Food intolerances].","authors":"Stephan C Bischoff","doi":"10.1007/s00108-021-01257-w","DOIUrl":"10.1007/s00108-021-01257-w","url":null,"abstract":"<p><p>Adverse reactions to food affect about one third of the population. They are based on very different mechanisms and are triggered by specific foods. They are divided into food intolerances, which manifest mainly in the gastrointestinal tract and food allergies, which can also cause extraintestinal symptoms and have an immunological genesis. In adults, food intolerances are significantly more common than food allergies with a prevalence of approximately 10-20%. The most important food intolerances are sugar intolerances, such as lactose and fructose intolerance but intolerances to wheat also play an increasing role. The diagnostics of food intolerances require extensive exclusion diagnostics, whereby in particular irritable bowel syndrome and intestinal dysbiosis must be differentiated. The therapy of food intolerance is primarily based on a targeted elimination diet. In this advanced education article the most important food intolerances are discussed.</p>","PeriodicalId":54924,"journal":{"name":"Internist","volume":" ","pages":"281-290"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39902774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
InternistPub Date : 2022-02-01DOI: 10.1007/s00108-021-01258-9
{"title":"Kongresse des BDI.","authors":"","doi":"10.1007/s00108-021-01258-9","DOIUrl":"https://doi.org/10.1007/s00108-021-01258-9","url":null,"abstract":"","PeriodicalId":54924,"journal":{"name":"Internist","volume":"63 2","pages":"193-197"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820369/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39745996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
InternistPub Date : 2022-02-01Epub Date: 2022-01-14DOI: 10.1007/s00108-021-01248-x
Christoph Fiehn
{"title":"[Treatment of rheumatoid arthritis and spondylarthritis with biologics].","authors":"Christoph Fiehn","doi":"10.1007/s00108-021-01248-x","DOIUrl":"https://doi.org/10.1007/s00108-021-01248-x","url":null,"abstract":"<p><p>Biologics are an integral part of modern strategies for treatment of rheumatoid arthritis (RA) and spondylarthritis (SpA), including psoriatic arthritis (PsA). Biologics are biotechnologically produced proteins that have inhibiting effects on humoral and cellular components of rheumatic inflammation. Substance classes used in rheumatology are tumor necrosis factor (TNF)-alpha, interleukin (IL)-1, IL‑6, IL-12, IL-17 and IL-23 inhibitors effective against cytokines as well as the T lymphocyte activation inhibitor abatacept and the B lymphocyte-depleting rituximab. There are clear recommendations for the use of biologics for RA patients inadequately responding to one or more conventional synthetic disease-modifying antirheumatic drugs and for ankylosing spondylitis (AS) and nonradiographical axial SpA patients with an inadequate response to at least two nonsteroidal antirheumatic drugs. For PsA the recommended use depends on the most prominent manifestations in each case. Treatment with biologics should follow the treat to target principle, with a defined and validated treatment target. Treatment in cases of RA and SpA should target remission or at least a low or minimum disease activity. The safety of treatment with biologics has been intensively investigated. There are very specific contraindications for individual substance classes with a focus on an increased risk of infections. The standard procedure before starting treatment with biologics includes the exclusion of latent tuberculosis and hepatitis B. The TNF-alpha inhibitors have a protective effect with respect to myocardial infarction, stroke and venous thromboembolism.</p>","PeriodicalId":54924,"journal":{"name":"Internist","volume":"63 2","pages":"135-142"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759427/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39697650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
InternistPub Date : 2022-02-01Epub Date: 2021-12-09DOI: 10.1007/s00108-021-01191-x
A Nuttebaum, P Ackermann, C Scholz
{"title":"[73/f-Conspicuous palpable findings of the right breast : Preparation for the medical specialist examination: part 124].","authors":"A Nuttebaum, P Ackermann, C Scholz","doi":"10.1007/s00108-021-01191-x","DOIUrl":"10.1007/s00108-021-01191-x","url":null,"abstract":"","PeriodicalId":54924,"journal":{"name":"Internist","volume":"63 Suppl 1","pages":"121-127"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39794970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
InternistPub Date : 2022-02-01Epub Date: 2021-09-16DOI: 10.1007/s00108-021-01146-2
A Arlt, C Meinhardt
{"title":"[41/f-Abdominal pain in the upper right-hand side : Preparation for the medical specialist examination: part 112].","authors":"A Arlt, C Meinhardt","doi":"10.1007/s00108-021-01146-2","DOIUrl":"10.1007/s00108-021-01146-2","url":null,"abstract":"","PeriodicalId":54924,"journal":{"name":"Internist","volume":"63 Suppl 1","pages":"60-64"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39441883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
InternistPub Date : 2022-02-01Epub Date: 2022-01-04DOI: 10.1007/s00108-021-01230-7
L Helbig, C Misgeld
{"title":"[81/f-Congested neck veins and cardiac murmur : Preparation for the medical specialist examination: part 108].","authors":"L Helbig, C Misgeld","doi":"10.1007/s00108-021-01230-7","DOIUrl":"10.1007/s00108-021-01230-7","url":null,"abstract":"","PeriodicalId":54924,"journal":{"name":"Internist","volume":"63 Suppl 1","pages":"41-46"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39660805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}