Journal of International Advanced Otology最新文献

{"title":"Sensorineural Hearing Impairment Recovery after Transmastoidal Surgery for a Petrous Apex Cholesterol Granuloma: A Case Report.","authors":"Stan van Keulen,&nbsp;Walter J Szweryn,&nbsp;Thijs T G Jansen,&nbsp;Stijn Bekkers,&nbsp;Henricus P M Kunst","doi":"10.5152/iao.2022.21349","DOIUrl":"https://doi.org/10.5152/iao.2022.21349","url":null,"abstract":"<p><p>Cholesterol granulomas are the most common primary lesions of the petrous apex. Although their benign character, impingement of critical neurovascular structures can cause significant symptomatology such as hearing impairment. We present unique results after treatment of a cholesterol granuloma located in the petrous apex causing sensorineural hearing impairment. A transmastoidal approach was performed using an intraoperative computed tomography-guided navigation system. The video, which is included for reference, illustrates clear drainage of the cyst and drain positioning. The hearing improved completely in the lower frequencies at 500 and 1000 Hz and with a 19 dB improvement in overall bone conduction in the affected ear.</p>","PeriodicalId":54793,"journal":{"name":"Journal of International Advanced Otology","volume":"18 5","pages":"447-450"},"PeriodicalIF":1.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/22/88/jiao-18-5-447.PMC9524395.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40700032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mucosal Melanoma of Eustachian Tube: A Case Report.","authors":"Yung Jee Kang,&nbsp;Min Bum Kim,&nbsp;Sang Duk Hong,&nbsp;Yang-Sun Cho","doi":"10.5152/iao.2022.21573","DOIUrl":"https://doi.org/10.5152/iao.2022.21573","url":null,"abstract":"Mucosal melanoma originating from the eustachian tube is very rare, and only 15 cases were reported so far. In this study, we report a case of mucosal melanoma from the eustachian tube which was surgically managed, followed by chemoradiotherapy. A 53-year-old man presented with a history of recurrent idiopathic hemotympanum and a dark red mass in the nasopharynx protruding from the eustachian tube orifice. Under an impression of mucosal melanoma from the eustachian tube, en-bloc surgical removal was performed using the infratemporal fossa approach type C combined with a transnasal endoscopic approach followed by postoperative chemoradiotherapy. However, the disease progressed to lung metastasis, and the patient died of the disease at 13 months postoperatively. The presenting case showed a poor progression despite a margin-free surgical resection followed by chemoradiotherapy. Additional trial of new treatment options is necessary to improve the poor prognosis.","PeriodicalId":54793,"journal":{"name":"Journal of International Advanced Otology","volume":"18 5","pages":"455-458"},"PeriodicalIF":1.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d0/3d/jiao-18-5-455.PMC9524376.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40351677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional Outcomes of Single-Stage Ossiculoplasty in Chronic Otitis Media With or Without Cholesteatoma.","authors":"Seongbin Park,&nbsp;Kang Hyeon Lim,&nbsp;Sung Jin Lim,&nbsp;Dong Heun Park,&nbsp;Yoon Chan Rah,&nbsp;June Choi","doi":"10.5152/iao.2022.21360","DOIUrl":"https://doi.org/10.5152/iao.2022.21360","url":null,"abstract":"<p><strong>Background: </strong>Two-stage ossiculoplasty has been widely used for hearing improvement in chronic otitis media with or without cholesteatoma. However, the outcomes of single-stage ossiculoplasty have not been fully clarified.The aim of this study is to determine whether the outcomes of single-stage ossiculoplasty are comparable with those of 2-stage ossiculoplasty in chronic otitis media with or without cholesteatoma.</p><p><strong>Methods: </strong>Medical records of 191 cases (187 patients) who underwent single-stage ossiculoplasty from January 2011 to May 2018 at our hospital were retrospectively reviewed.</p><p><strong>Results: </strong>Polycel and titanium were used in 56 and 135 cases, respectively. In chronic otitis media without cholesteatoma, the success rate of polycel and titanium partial ossicular replacement prosthesis was 80.7% and 81.6%, respectively. In chronic otitis media with cholesteatoma, the success rate of polycel and titanium partial ossicular replacement prosthesis was 63.6% and 64.6%, respectively, while that of polycel and titanium total ossicular replacement prosthesis was 45.9% and 47.8%, respectively.</p><p><strong>Conclusion: </strong>These results suggest that single-stage ossiculoplasty is a suitable option for recovering postoperative hearing in chronic otitis media with or without cholesteatoma. Thus, if middle ear inflammation can be sufficiently treated in the first stage, single-stage ossiculoplasty is a suitable option for chronic otitis media with or without cholesteatoma.</p>","PeriodicalId":54793,"journal":{"name":"Journal of International Advanced Otology","volume":"18 5","pages":"415-419"},"PeriodicalIF":1.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9a/ed/jiao-18-5-415.PMC9524377.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40700033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Cytotoxic and Ototoxic Effects of Lipoplatin and Cisplatin in Neuroblastoma In Vivo Tumor Model.","authors":"Hande Evin Eskicioğlu, Yüksel Olgun, Tekincan Çağrı Aktaş, Safiye Aktas, Efsun Kolatan, Efe Serinan, Zekiye Altun, Günay Kırkım, Osman Yılmaz, Nur Olgun","doi":"10.5152/iao.2022.21268","DOIUrl":"10.5152/iao.2022.21268","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to compare the cytotoxic, cytostatic, and ototoxic effects of lipoplatin compared to cisplatin application in the subcutaneous xenograft nude mouse neuroblastoma tumor model.</p><p><strong>Methods: </strong>In this study, C1300 neuroblastoma cells were administered subcutaneously to 21 male nude mice. When the tumor reached 150 mm3 diameter, mice were randomized into 3 groups. Saline, cisplatin, and lipoplatin were given intraperitoneally. The auditory function tests were performed before administration and 72 hours after administration. Mice were sacrificed and the tumor and cochlea were removed after 72 hours. Histopathologic evaluation of necrosis and apoptosis was determined by the TdT-mediated dUTP-biotin nick end labeling (TUNEL) method. Cyclooxygenase 2, superoxide dismutase 2, and inducible nitric oxide synthase levels were determined by immunohistochemistry in tissue samples.</p><p><strong>Results: </strong>Apoptosis and necrosis rates were higher in lipoplatin group than in cisplatin group (P=.035 and P=.010, respectively) in tumor tissue. In the spiral ganglion, apoptosis and necrosis were lower in the lipoplatin group than in cisplatin group (P=.002 and P=.002, respectively). Cyclooxygenase 2 pattern in the cochlea was positive in both control and lipoplatin group and negative in cisplatin group (P=.001). Superoxide dismutase 2 and inducible nitric oxide synthase 2 protein expressions showed no difference between groups. The auditory functions were similar to baseline values and had a better threshold value in lipoplatin group than cisplatin group.</p><p><strong>Conclusion: </strong>For the treatment of neuroblastoma, the use of lipoplatin seems to be beneficial in reducing side effects of cisplatin. We recommend that the mechanism of these properties of lipoplatin should be evaluated in further studies.</p>","PeriodicalId":54793,"journal":{"name":"Journal of International Advanced Otology","volume":"18 5","pages":"392-398"},"PeriodicalIF":1.2,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8d/f0/jiao-18-5-392.PMC9524363.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40351760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Titanium Prostheses for Treating Posttraumatic Ossicular Chain Disruption.","authors":"Lukasz Plichta,&nbsp;Aleksandra Dabkowska,&nbsp;Sandra Wawszczyk-Frohlich,&nbsp;Henryk Skarzynski,&nbsp;Piotr Henryk Skarzynski","doi":"10.5152/iao.2022.21369","DOIUrl":"https://doi.org/10.5152/iao.2022.21369","url":null,"abstract":"<p><strong>Background: </strong>Posttraumatic chain disruption may be caused by blunt head trauma, barotrauma, or a penetrating foreign body. In cases of severe damage to the incus, or its absence, a titanium prosthesis is a good option for reconstructing the ossicular chain.</p><p><strong>Methods: </strong>A retrospective analysis was performed on 24 cases of posttraumatic ossicular chain disruption that had been treated with a titanium partial or total ossicular replacement prosthesis. Air conduction, bone conduction, and air-bone gap were measured before, 6-12 months after, and more than 2 years after the operation. Hearing thresholds were calculated as the mean of 4 frequencies (0.5, 1, 2, and 4 kHz).</p><p><strong>Results: </strong>The most common cause of ossicular chain disruption was blunt head trauma due to a traffic accident (9 of 24 cases), and there were also a diverse group of foreign bodies which caused damage. In cases where the incus was absent, or significantly damaged, titanium ossiculoplasties were performed (partial or total ossicular replacement prosthesis depending on the presence of the stapes superstructure). Analysis showed a significant improvement in average air conduction threshold and in air-bone gap after surgery (P < .05). Closure of the air-bone gap to within 20 dB was observed in 67% of patients.</p><p><strong>Conclusions: </strong>Although posttraumatic ossicular chain disruption is not common, it is suspected whenever conductive hearing loss persists for several months after injury. In such cases, ossiculoplasty with a titanium prosthesis is likely to provide satisfactory audiological results.</p>","PeriodicalId":54793,"journal":{"name":"Journal of International Advanced Otology","volume":"18 5","pages":"411-414"},"PeriodicalIF":1.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2c/9f/jiao-18-5-411.PMC9524405.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40351761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Behavioral Evaluation of 3 Smartphone-Based Hearing Aid Apps for Patients with Mild Hearing Loss: An Exploratory Pilot Study.","authors":"Miseung Koo,&nbsp;Willy Nguyen,&nbsp;Jun Ho Lee,&nbsp;Seung-Ha Oh,&nbsp;Moo Kyun Park","doi":"10.5152/iao.2022.21469","DOIUrl":"https://doi.org/10.5152/iao.2022.21469","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to evaluate the behavioral performance of a selection of currently available hearing aid apps in patients with mild hearing loss.</p><p><strong>Methods: </strong>We investigated 3 user-friendly hearing aid apps (EarMachine, Sound Amplifier, and Petralex) with real-ear measurement, warbletone audiometry, word recognition testing in unaided and aided conditions, and hearing-in-noise tests in quiet and noise-front conditions in a group of users with mild hearing impairment (n=7) as a pilot for a future long-term investigation. Results from the apps were compared with those of a conventional hearing aid.</p><p><strong>Results: </strong>Hearing aids showed greater gain at 1 and 3 kHz than hearing aid apps in real-ear insertion gain of real-ear measurements. Hearing aids tended to have greater gain than hearing aid apps at 2 and 3 kHz in the sound field audiometry test. The clinical performance of the listeners tended to be better when using a hearing aid and Petralex (13% and 6% improvement in word recognition score, respectively), while EarMachine and Sound Amplifier conferred limited user benefit. The hearing aid apps did not improve signal-to-noise ratio in comparison with the unaided condition in the hearing-in-noise test.</p><p><strong>Conclusions: </strong>Some hearing aid apps were beneficial for patients with mild hearing loss in terms of amplification, but participants using the apps showed no improvements in hearing-in-noise tests.</p>","PeriodicalId":54793,"journal":{"name":"Journal of International Advanced Otology","volume":"18 5","pages":"399-404"},"PeriodicalIF":1.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3a/f0/jiao-18-5-399.PMC9524353.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40351759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical Outcomes of Using Temporoparietal Fasciocutaneus and Temporoparietal Pedicle Flap for Auricular Reconstruction.","authors":"Zwierz Aleksander,&nbsp;Masna Krystyna","doi":"10.5152/iao.2022.21545","DOIUrl":"https://doi.org/10.5152/iao.2022.21545","url":null,"abstract":"<p><strong>Background: </strong>Temporoparietal fasciocutaneus and temporoparietal fascial pedicle flaps play an important role among many techniques for auricular reconstruction. Because of their unique characteristics, the flaps based on the superficial temporal artery may be used for various types of reconstruction.</p><p><strong>Methods: </strong>In this article, we present several applications of the temporoparietal fasciocutaneus and temporoparietal fascial pedicle flaps in the reconstruction of defects after ear resection, including the use of the sandwich flap.</p><p><strong>Results: </strong>Our experiences presented in this case series confirm the reconstructive potential of the flaps, also in patients in whom the Vistafix® system was used for reconstruction of the ear.</p><p><strong>Conclusions: </strong>In all cases described herein, the use of the pedicle flaps resulted in optimal healing and satisfactory cosmetic and functional outcomes.</p>","PeriodicalId":54793,"journal":{"name":"Journal of International Advanced Otology","volume":"15 5","pages":"426-432"},"PeriodicalIF":1.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3d/ba/jiao-18-5-426.PMC9524409.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40351762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expression of c-Jun and KROX-20 Following Facial Nerve Injury and Recovery in Rats.","authors":"In Hyeok Kim,&nbsp;Jae Min Lee,&nbsp;Jun Yang Jung,&nbsp;Hwa Sung Rim,&nbsp;Dae Woong Kang,&nbsp;Sang Hoon Kim,&nbsp;Seung Geun Yeo","doi":"10.5152/iao.2022.21367","DOIUrl":"https://doi.org/10.5152/iao.2022.21367","url":null,"abstract":"<p><strong>Background: </strong>This study evaluated whether recovery from facial paralysis was associated with the expression of Krox-20 and c-Jun genes that are shown to be related to facial nerve regeneration after facial nerve compression and cutting.</p><p><strong>Methods: </strong>The left facial nerves of 24 male Sprague-Dawley rats aged 6 weeks were subjected to crushing or cutting injury. Whisker movements of the vibrissae muscle and blink reflexes of the eyelids were measured on days 4 and 14 after facial nerve injury. The facial nerves on both sides were removed, and the expression of c-Jun and Krox-20 proteins was evaluated by Western blotting.</p><p><strong>Results: </strong>The level of expression of Krox-20 on day 4 was lower in the crushing group, especially in the cutting group than in the control group (P < .05), but there was no statistically significant difference on day 14 (P > .05). The expression of c-Jun expression was significantly higher in the crushing and cutting groups than in the control group on days 4 and 14 (P < .05).</p><p><strong>Conclusion: </strong>The degree of facial paralysis was more severe and the recovery rate was lower in the cutting group than in the crushing group. The levels of expression of Krox-20 and c-Jun were associated with facial nerve regeneration after facial nerve injury.</p>","PeriodicalId":54793,"journal":{"name":"Journal of International Advanced Otology","volume":"18 5","pages":"420-425"},"PeriodicalIF":1.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/00/53/jiao-18-5-420.PMC9524407.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40701470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cochlear Implantation for Patients with a Vestibular Schwannoma: Effect on Tinnitus Handicap.","authors":"Niels West,&nbsp;Marie Bunne,&nbsp;Hjalte Sass,&nbsp;Per Cayé-Thomasen","doi":"10.5152/iao.2022.21541","DOIUrl":"https://doi.org/10.5152/iao.2022.21541","url":null,"abstract":"<p><strong>Background: </strong>Tinnitus is a common symptom among individuals with a vestibular schwannoma. In recent years, cochlear implantation, often combined with tumor resection, is an increasingly used option in the management of these patients. The existing literature does not account well for the effect of treatment on tinnitus burden. Thus, this paper reports the effect of cochlear implantation on tinnitus in a cohort of vestibular schwannoma patients.</p><p><strong>Methods: </strong>Individuals with vestibular schwannoma undergoing cochlear implantation were retrospectively reviewed for tinnitus burden, as evaluated by the Tinnitus Handicap Inventory, administered before and after implantation. The outcome measures were total Tinnitus Handicap Inventory score and scores from each of the Tinnitus Handicap Inventory subdomains (functional, emotional, and catastrophic). In addition, the existing literature on tinnitus in cochlear implanted vestibular schwannoma patients was reviewed.</p><p><strong>Results: </strong>Tumor management consisted of simultaneous resection (77%), previous resection (9%), observation (9%) and radiation (5%). Complete Tinnitus Handicap Inventory evaluation was available for 17 patients. After implantation, the median THItotal changed from 18 to 10 (P = .0006), the subdomain THIfunctional from 10 to 3 (P = .006), the THIemotional from 3 to 0 (P = .023) and the THIcatastrophic from 6 to 1 (P = .004). In the scarcely reported tinnitus outcomes in the literature, most but not all cases experienced a decrease in tinnitus.</p><p><strong>Conclusions: </strong>The tinnitus burden is significantly reduced by cochlear implantation in individuals with a vestibular schwannoma. This agrees with findings for other etiologies indicating cochlear implantation and supports the eligibility for hearing rehabilitation with a cochlear implant for this specific group of patients.</p>","PeriodicalId":54793,"journal":{"name":"Journal of International Advanced Otology","volume":"18 5","pages":"382-387"},"PeriodicalIF":1.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6b/33/jiao-18-5-382.PMC9524396.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40351756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Diagnostic Value of 1.5T Versus 3.0T Magnetic Resonance Imaging Intratympanic Gadolinium Inner Ear Enhancement in Patients with Meniere's Disease.","authors":"Yonping Han,&nbsp;Junyi Zhang,&nbsp;Lei Lui,&nbsp;Xia Gao,&nbsp;Lei Wu,&nbsp;Xueqin Du,&nbsp;Wenjie Fan,&nbsp;Ying Xing,&nbsp;Xi Chen","doi":"10.5152/iao.2022.21496","DOIUrl":"https://doi.org/10.5152/iao.2022.21496","url":null,"abstract":"<p><strong>Background: </strong>A comparative study of 1.5T and 3.0T magnetic resonance imaging inner ear gadolinium enhancement was carried out to further explore the practicality and universality of 1.5T magnetic resonance imaging in the diagnosis of inner ear labyrinthine hydrops positive imaging.</p><p><strong>Methods: </strong>This dual case-control study was conducted on 25 patients with Meniere's disease (experimental group), diagnosed by People's Hospital of Ordos Dongsheng District between April 2017 and April 2019 and 51 patients with Meniere's disease (control group), diagnosed by People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine between March 2010 and February 2011 and published on Chinese Medical Journal in 2011. Both groups were injected with gadolinium diluent into bilateral tympanic chambers through the tympanic membrane, and 3 dimensional-Fluid Attenuated Inversion Recovery (FLAIR) magnetic resonance imaging scanning of the inner ear was performed 24 hours later. The results of the 2 groups were observed, calculated, and statistically processed.</p><p><strong>Results: </strong>The positive rate of membranous labyrinthine hydrops was 96% (24/25) in the experimental group and 96.1% (49/51) in the control group. The results are very close.</p><p><strong>Conclusion: </strong>In clinical diagnoses of Meniere's disease, 1.5T magnetic resonance imaging and 3.0T magnetic resonance imaging have the same value and significance.</p>","PeriodicalId":54793,"journal":{"name":"Journal of International Advanced Otology","volume":"18 5","pages":"388-391"},"PeriodicalIF":1.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/58/3f/jiao-18-5-388.PMC9524368.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40351758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}