{"title":"Preparation and Preliminary Scale-Up Validation of Polycaprolactone Microspheres for Facial Filling Based on Intelligent Algorithm Optimization","authors":"Shuhui Kang, Hao Sui, Ruixuan Wang, Xiaoya Pang, Yuchao Qiao, Min Zhang, 赵志娟, Lixia Qiu, Ling Tong, Yunlan Li, Qingping Tian","doi":"10.1080/00222348.2026.2718429","DOIUrl":"https://doi.org/10.1080/00222348.2026.2718429","url":null,"abstract":"To simultaneously achieve the goals of minimizing particle size within the 25–40 μm range and obtaining the narrowest possible particle size distribution (lowest Span value), the formulations of polycaprolactone microspheres (PCL-MS) were screened. After applying single-factor studies and the Box-Behnken design method, formulation optimization was conducted via the Nondominated Sorting Genetic Algorithm-II. From the Pareto non-inferiority solution sets containing 30 formulations, the 12th and 21st formulations were selected for experimental verification, since they were the closest to the target. The scale of formulation 21 was magnified tenfold. The resulting PCL-MS exhibited no significant changes in particle size or Span value. Scanning electron microscopy revealed a smooth, rounded MS surface, and organic solvent residue testing met regulatory requirements. This fully demonstrated the applicability of the optimized formulation under scaled-up conditions, providing a formulation reference for industrial quality control of PCL-MS.","PeriodicalId":54787,"journal":{"name":"Journal of Macromolecular Science Part B-Physics","volume":"1 1","pages":"1-16"},"PeriodicalIF":0.0,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148861220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fabrication of an Asymmetric PCL-HAP/CS Bilayer Composite Membrane with Dual Osteogenic and Fibrogenic Functions for Guided Bone Regeneration","authors":"Guijuan Li, Enhui Wang, Kangkang Zhao, Wei Xia, Fuli Tian, Yanqiang Li","doi":"10.1080/00222348.2026.2650554","DOIUrl":"https://doi.org/10.1080/00222348.2026.2650554","url":null,"abstract":"","PeriodicalId":54787,"journal":{"name":"Journal of Macromolecular Science Part B-Physics","volume":"1 1","pages":"1-28"},"PeriodicalIF":0.0,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147877386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Suwei Gao, Yucheng Wang, Liang Li, Xi Chang Wang, Qiaofeng Wei, Shuyue Zhu, Rangtong Liu
{"title":"Preparation of Wave Absorbing Coatings Blended Waterborne Polyurethane with Nano Fe <sub>3</sub> O <sub>4</sub> /MWCNTs and Their Electromagnetic Absorption Properties","authors":"Suwei Gao, Yucheng Wang, Liang Li, Xi Chang Wang, Qiaofeng Wei, Shuyue Zhu, Rangtong Liu","doi":"10.1080/00222348.2025.2612240","DOIUrl":"https://doi.org/10.1080/00222348.2025.2612240","url":null,"abstract":"","PeriodicalId":54787,"journal":{"name":"Journal of Macromolecular Science Part B-Physics","volume":"1 1","pages":"1-24"},"PeriodicalIF":0.0,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147888185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"3D-Printed Auricular Scaffold Based on Porous UHMWPE Reinforced with PVA/CS Double-Network Hydrogel","authors":"Jian Yao, Jifan Zhan, Hanwu Liu, Tingting Yan","doi":"10.1080/00222348.2025.2572793","DOIUrl":"https://doi.org/10.1080/00222348.2025.2572793","url":null,"abstract":"Auricular reconstruction remains a significant challenge in tissue engineering due to the auricle’s complex anatomy and functional requirements. To address the limitations of autologous cartilage grafts, we developed a composite scaffold consisting of porous ultra-high molecular weight polyethylene (UHMWPE) integrated with a polyvinyl alcohol/chitosan (PVA/CS) double-network hydrogel reinforced with 2 wt% nano-hydroxyapatite (HA). The scaffold was fabricated via powder sintering and physical crosslinking and exhibited high porosity (>41%), a tensile strength of 2.80 MPa, and enhanced water retention. The addition of HA improved both the mechanical strength and antibacterial properties of the composite. The hydrogel component demonstrated stable swelling behavior, hemolysis rates below 5%, and good cytocompatibility. These findings demonstrate that the UHMWPE/PVA-CS/HA composite scaffold, combining the rigidity of a sintered porous framework with the flexibility and bioactivity of a reinforced hydrogel, offers a novel and promising platform for patient-specific auricular reconstruction with balanced mechanical, biological, and antibacterial properties.","PeriodicalId":54787,"journal":{"name":"Journal of Macromolecular Science Part B-Physics","volume":"1 1","pages":"1-25"},"PeriodicalIF":0.0,"publicationDate":"2025-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147911582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Guangming Zhou, Tao Liu, Lihu Fu, Bingyan Yu, Simiao Yu, Zian Xu, Shiyuan Xu, Jie Liu, Gang Lu
{"title":"Preparation and Characterization of Polyethyleneimine/Sorbitan Monooleate Blended Polypropylene Antifogging Films","authors":"Guangming Zhou, Tao Liu, Lihu Fu, Bingyan Yu, Simiao Yu, Zian Xu, Shiyuan Xu, Jie Liu, Gang Lu","doi":"10.1080/00222348.2025.2562451","DOIUrl":"https://doi.org/10.1080/00222348.2025.2562451","url":null,"abstract":"","PeriodicalId":54787,"journal":{"name":"Journal of Macromolecular Science Part B-Physics","volume":"1 1","pages":"1-15"},"PeriodicalIF":0.0,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147903130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}